ATE279411T1 - Fluorszierende marker - Google Patents

Fluorszierende marker

Info

Publication number
ATE279411T1
ATE279411T1 AT99937054T AT99937054T ATE279411T1 AT E279411 T1 ATE279411 T1 AT E279411T1 AT 99937054 T AT99937054 T AT 99937054T AT 99937054 T AT99937054 T AT 99937054T AT E279411 T1 ATE279411 T1 AT E279411T1
Authority
AT
Austria
Prior art keywords
fluorescent markers
compounds
medicaments
chem
diagnosis
Prior art date
Application number
AT99937054T
Other languages
English (en)
Inventor
Yoshimitsu Nagao
Susumu Ito
Original Assignee
Daiichi Pure Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pure Chemicals Co Ltd filed Critical Daiichi Pure Chemicals Co Ltd
Application granted granted Critical
Publication of ATE279411T1 publication Critical patent/ATE279411T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/086—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines more than five >CH- groups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Vessels And Coating Films For Discharge Lamps (AREA)
AT99937054T 1998-08-12 1999-08-12 Fluorszierende marker ATE279411T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22824198 1998-08-12
PCT/JP1999/004382 WO2000009502A1 (en) 1998-08-12 1999-08-12 Fluorescent labelling reagents

Publications (1)

Publication Number Publication Date
ATE279411T1 true ATE279411T1 (de) 2004-10-15

Family

ID=16873380

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99937054T ATE279411T1 (de) 1998-08-12 1999-08-12 Fluorszierende marker

Country Status (6)

Country Link
US (1) US6403625B1 (de)
EP (1) EP1104761B1 (de)
AT (1) ATE279411T1 (de)
AU (1) AU5197599A (de)
DE (1) DE69921151T2 (de)
WO (1) WO2000009502A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000032175A2 (en) * 1998-12-02 2000-06-08 Pfizer Products Inc. METHODS AND COMPOSITIONS FOR RESTORING CONFORMATIONAL STABILITY OF A PROTEIN OF THE p53 FAMILY
AU3599601A (en) * 2000-02-28 2001-09-03 Daiichi Pure Chemicals Co Ltd Measuring method using long life fluorescence of excitation type
EP1553408A4 (de) * 2002-07-08 2005-08-17 Tetsuo Nagano Fluoreszenzsonde
US20060211122A1 (en) * 2002-10-16 2006-09-21 Tetsuo Nagano Reagents for the measurement of peroxynitrites
US7696245B2 (en) * 2003-03-28 2010-04-13 Sekisui Medical Co., Ltd. Fluorescent probe for zinc
JP2005194244A (ja) * 2004-01-09 2005-07-21 Shigenobu Yano 亜鉛イオン蛍光センサー
EP2438847A3 (de) * 2004-06-18 2012-11-07 David R. Elmaleh Kontrastmittel und dessen Verwendung in einer Intravaskuläre Bildgebungsvorrichtung
WO2007091661A1 (ja) * 2006-02-08 2007-08-16 National Institute Of Advanced Industrial Science And Technology 分子イメージングに適した糖鎖修飾リポソームならびにその利用および製造
JP5858932B2 (ja) 2010-02-04 2016-02-10 モルフォテック, インコーポレイテッド クロロトキシンポリペプチドおよびコンジュゲートならびにその使用
ES2601182T3 (es) * 2010-05-11 2017-02-14 Fred Hutchinson Cancer Research Center Variantes de clorotoxina, conjugados y métodos para su utilización
EP2598174B1 (de) 2010-07-30 2019-03-27 SmartDyeLivery GmbH Messverfahren zur bestimmung einer organfunktion
US9314304B2 (en) 2010-12-08 2016-04-19 Lumicell, Inc. Methods and system for image guided cell ablation with microscopic resolution
SG11201504600UA (en) 2012-12-10 2015-07-30 Hutchinson Fred Cancer Res Methods for screening
WO2014152389A1 (en) 2013-03-14 2014-09-25 Lumicell, Inc. Imaging agent for detection of diseased cells
US11559580B1 (en) 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
US12048732B2 (en) 2016-04-15 2024-07-30 Blaze Bioscience, Inc. Methods of treating breast cancer
EP3755381B1 (de) * 2018-02-21 2025-01-01 Sorbonne Université Auf entzündungen gerichtete, optische kontrastmittel
US12527880B2 (en) * 2018-08-31 2026-01-20 The Regents Of The University Of California Cyanine-based telodendrimers and uses for treating cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE580869A (de) 1957-06-05
JP3394566B2 (ja) 1993-07-16 2003-04-07 富士写真フイルム株式会社 癌の光化学療法用医薬組成物
FR2710060B1 (fr) 1993-09-17 1995-11-17 Rech Biolog Et Procédé de préparation de benz[e]indoles substitués de pureté élevée et leurs sels alcalins.
JP3896176B2 (ja) * 1996-05-21 2007-03-22 浜松ホトニクス株式会社 近赤外線蛍光トレーサーおよび蛍光イメージング方法

Also Published As

Publication number Publication date
EP1104761A1 (de) 2001-06-06
WO2000009502A1 (en) 2000-02-24
DE69921151D1 (de) 2004-11-18
EP1104761A4 (de) 2001-12-12
EP1104761B1 (de) 2004-10-13
US6403625B1 (en) 2002-06-11
AU5197599A (en) 2000-03-06
DE69921151T2 (de) 2005-06-02

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Legal Events

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