ATE279411T1 - Fluorszierende marker - Google Patents

Fluorszierende marker

Info

Publication number
ATE279411T1
ATE279411T1 AT99937054T AT99937054T ATE279411T1 AT E279411 T1 ATE279411 T1 AT E279411T1 AT 99937054 T AT99937054 T AT 99937054T AT 99937054 T AT99937054 T AT 99937054T AT E279411 T1 ATE279411 T1 AT E279411T1
Authority
AT
Austria
Prior art keywords
fluorescent markers
compounds
medicaments
chem
diagnosis
Prior art date
Application number
AT99937054T
Other languages
English (en)
Inventor
Yoshimitsu Nagao
Susumu Ito
Original Assignee
Daiichi Pure Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pure Chemicals Co Ltd filed Critical Daiichi Pure Chemicals Co Ltd
Application granted granted Critical
Publication of ATE279411T1 publication Critical patent/ATE279411T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032Methine dyes, e.g. cyanine dyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/005Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056Peptides, proteins, polyamino acids
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/086Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines more than five >CH- groups
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Vessels And Coating Films For Discharge Lamps (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
AT99937054T 1998-08-12 1999-08-12 Fluorszierende marker ATE279411T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22824198 1998-08-12
PCT/JP1999/004382 WO2000009502A1 (en) 1998-08-12 1999-08-12 Fluorescent labelling reagents

Publications (1)

Publication Number Publication Date
ATE279411T1 true ATE279411T1 (de) 2004-10-15

Family

ID=16873380

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99937054T ATE279411T1 (de) 1998-08-12 1999-08-12 Fluorszierende marker

Country Status (6)

Country Link
US (1) US6403625B1 (de)
EP (1) EP1104761B1 (de)
AT (1) ATE279411T1 (de)
AU (1) AU5197599A (de)
DE (1) DE69921151T2 (de)
WO (1) WO2000009502A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1329493A (zh) * 1998-12-02 2002-01-02 辉瑞产品公司 恢复p53家族蛋白质的构象稳定性的方法和组合物
KR20030011777A (ko) * 2000-02-28 2003-02-11 다이이치 가가쿠 야쿠힝 가부시키가이샤 장수명 여기형 형광을 이용하는 측정방법
US7524974B2 (en) * 2002-07-08 2009-04-28 Tetsuo Nagano Fluorescent probe
WO2004040296A1 (ja) * 2002-10-16 2004-05-13 Daiichi Pure Chemicals Co., Ltd. パーオキシナイトライト測定用試薬
US7696245B2 (en) * 2003-03-28 2010-04-13 Sekisui Medical Co., Ltd. Fluorescent probe for zinc
JP2005194244A (ja) * 2004-01-09 2005-07-21 Shigenobu Yano 亜鉛イオン蛍光センサー
EP1765172B1 (de) * 2004-06-18 2013-04-24 Elmaleh, David R. Intravaskuläre bildgebende vorrichtung und ihre verwendungen
WO2007091661A1 (ja) * 2006-02-08 2007-08-16 National Institute Of Advanced Industrial Science And Technology 分子イメージングに適した糖鎖修飾リポソームならびにその利用および製造
CN102844044B (zh) 2010-02-04 2016-10-26 摩尔弗泰克有限公司 氯毒素多肽和结合物及其应用
EP3165533B1 (de) 2010-05-11 2020-04-08 Fred Hutchinson Cancer Research Center Chlorotoxin-varianten und -konjugate sowie verfahren zu deren verwendung
DK2598174T3 (da) 2010-07-30 2019-06-24 Smartdyelivery Gmbh Målemetode til bestemmelse af en organfunktion
US9314304B2 (en) 2010-12-08 2016-04-19 Lumicell, Inc. Methods and system for image guided cell ablation with microscopic resolution
CA2913029A1 (en) 2012-12-10 2014-06-19 Fred Hutchinson Cancer Research Center Lipocalin fusion partners
US9763577B2 (en) * 2013-03-14 2017-09-19 Lumicell, Inc. Imaging agent for detection of diseased cells
US11559580B1 (en) 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
US12048732B2 (en) 2016-04-15 2024-07-30 Blaze Bioscience, Inc. Methods of treating breast cancer
EP3755381B1 (de) * 2018-02-21 2025-01-01 Sorbonne Université Auf entzündungen gerichtete, optische kontrastmittel
US12527880B2 (en) * 2018-08-31 2026-01-20 The Regents Of The University Of California Cyanine-based telodendrimers and uses for treating cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE580869A (de) 1957-06-05
JP3394566B2 (ja) * 1993-07-16 2003-04-07 富士写真フイルム株式会社 癌の光化学療法用医薬組成物
FR2710060B1 (fr) * 1993-09-17 1995-11-17 Rech Biolog Et Procédé de préparation de benz[e]indoles substitués de pureté élevée et leurs sels alcalins.
JP3896176B2 (ja) * 1996-05-21 2007-03-22 浜松ホトニクス株式会社 近赤外線蛍光トレーサーおよび蛍光イメージング方法

Also Published As

Publication number Publication date
EP1104761A4 (de) 2001-12-12
AU5197599A (en) 2000-03-06
WO2000009502A1 (en) 2000-02-24
EP1104761B1 (de) 2004-10-13
EP1104761A1 (de) 2001-06-06
DE69921151T2 (de) 2005-06-02
DE69921151D1 (de) 2004-11-18
US6403625B1 (en) 2002-06-11

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Legal Events

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