ATE279426T1 - VERFAHREN ZUR HERSTELLUNG VON AZA-MAKROLIDEN MIT 4ß(R)-NH2 - Google Patents
VERFAHREN ZUR HERSTELLUNG VON AZA-MAKROLIDEN MIT 4ß(R)-NH2Info
- Publication number
- ATE279426T1 ATE279426T1 AT00900224T AT00900224T ATE279426T1 AT E279426 T1 ATE279426 T1 AT E279426T1 AT 00900224 T AT00900224 T AT 00900224T AT 00900224 T AT00900224 T AT 00900224T AT E279426 T1 ATE279426 T1 AT E279426T1
- Authority
- AT
- Austria
- Prior art keywords
- macrolids
- aza
- producing
- stereoselective
- compound
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000707 stereoselective effect Effects 0.000 abstract 2
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 238000006073 displacement reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 230000000269 nucleophilic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9900459A FR2788524B1 (fr) | 1999-01-18 | 1999-01-18 | Procede utile pour transformer la fonction 4"(s)-oh du motif cladinose d'un aza macrolide en 4"(r)-nh2 |
| PCT/FR2000/000089 WO2000042056A1 (fr) | 1999-01-18 | 2000-01-17 | Procede pour preparer un aza-macrolide avec 4'' (r)- nh¿2? |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE279426T1 true ATE279426T1 (de) | 2004-10-15 |
Family
ID=9540950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00900224T ATE279426T1 (de) | 1999-01-18 | 2000-01-17 | VERFAHREN ZUR HERSTELLUNG VON AZA-MAKROLIDEN MIT 4ß(R)-NH2 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | USRE40040E1 (de) |
| EP (1) | EP1144428B1 (de) |
| JP (1) | JP2003505340A (de) |
| AT (1) | ATE279426T1 (de) |
| AU (1) | AU768838B2 (de) |
| BR (1) | BRPI0007593B8 (de) |
| CA (1) | CA2359967C (de) |
| DE (1) | DE60014849T2 (de) |
| DK (1) | DK1144428T3 (de) |
| ES (1) | ES2232414T3 (de) |
| FR (1) | FR2788524B1 (de) |
| NZ (1) | NZ513025A (de) |
| PT (1) | PT1144428E (de) |
| WO (1) | WO2000042056A1 (de) |
| ZA (1) | ZA200105825B (de) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55151598A (en) * | 1979-05-11 | 1980-11-26 | Taisho Pharmaceut Co Ltd | Erythromycin a derivative and its preparation |
| CA2064634C (en) * | 1991-04-04 | 1998-08-04 | James V. Heck | 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions |
| EP0549040A1 (de) * | 1991-12-20 | 1993-06-30 | Merck & Co. Inc. | Verfahren zur Herstellung von 4"-Derivaten von 9-Deoxo-8a-Aza-8a-Alkyl-8a-Homoerythromycin A |
| PT679657E (pt) * | 1994-04-27 | 2003-11-28 | Novartis Ag | Nucleosidos e oligonucleotidos com grupos 2'-eter |
| JP2003512290A (ja) * | 1997-09-10 | 2003-04-02 | メルク エンド カムパニー インコーポレーテッド | 家畜抗菌剤としての８ａ−アザライド |
| GB9806029D0 (en) * | 1998-03-20 | 1998-05-20 | Merck & Co Inc | 8a-Azalides as veterinary antimicrobial agents |
-
1999
- 1999-01-18 FR FR9900459A patent/FR2788524B1/fr not_active Expired - Lifetime
-
2000
- 2000-01-17 EP EP00900224A patent/EP1144428B1/de not_active Expired - Lifetime
- 2000-01-17 AU AU19870/00A patent/AU768838B2/en not_active Expired
- 2000-01-17 ES ES00900224T patent/ES2232414T3/es not_active Expired - Lifetime
- 2000-01-17 CA CA2359967A patent/CA2359967C/en not_active Expired - Lifetime
- 2000-01-17 BR BRPI0007593A patent/BRPI0007593B8/pt not_active IP Right Cessation
- 2000-01-17 DE DE60014849T patent/DE60014849T2/de not_active Expired - Lifetime
- 2000-01-17 DK DK00900224T patent/DK1144428T3/da active
- 2000-01-17 PT PT00900224T patent/PT1144428E/pt unknown
- 2000-01-17 WO PCT/FR2000/000089 patent/WO2000042056A1/fr not_active Ceased
- 2000-01-17 NZ NZ513025A patent/NZ513025A/en not_active IP Right Cessation
- 2000-01-17 AT AT00900224T patent/ATE279426T1/de active
- 2000-01-17 JP JP2000593623A patent/JP2003505340A/ja active Pending
-
2001
- 2001-07-16 ZA ZA200105825A patent/ZA200105825B/en unknown
-
2005
- 2005-09-09 US US11/223,912 patent/USRE40040E1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2232414T3 (es) | 2005-06-01 |
| DE60014849D1 (de) | 2004-11-18 |
| CA2359967A1 (en) | 2000-07-20 |
| CA2359967C (en) | 2011-08-30 |
| DK1144428T3 (da) | 2005-02-14 |
| BR0007593A (pt) | 2001-11-06 |
| BR0007593B1 (pt) | 2014-01-28 |
| ZA200105825B (en) | 2002-05-08 |
| EP1144428A1 (de) | 2001-10-17 |
| FR2788524B1 (fr) | 2002-04-26 |
| NZ513025A (en) | 2003-11-28 |
| EP1144428B1 (de) | 2004-10-13 |
| AU1987000A (en) | 2000-08-01 |
| USRE40040E1 (en) | 2008-01-29 |
| PT1144428E (pt) | 2005-02-28 |
| JP2003505340A (ja) | 2003-02-12 |
| FR2788524A1 (fr) | 2000-07-21 |
| BRPI0007593B8 (pt) | 2021-05-25 |
| WO2000042056A1 (fr) | 2000-07-20 |
| AU768838B2 (en) | 2004-01-08 |
| DE60014849T2 (de) | 2006-03-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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