ATE280388T1 - Verfahren und vorrichtung zur messung von hämostase - Google Patents

Verfahren und vorrichtung zur messung von hämostase

Info

Publication number
ATE280388T1
ATE280388T1 AT00908771T AT00908771T ATE280388T1 AT E280388 T1 ATE280388 T1 AT E280388T1 AT 00908771 T AT00908771 T AT 00908771T AT 00908771 T AT00908771 T AT 00908771T AT E280388 T1 ATE280388 T1 AT E280388T1
Authority
AT
Austria
Prior art keywords
holder
blood sample
measuring
torque
adjacent parts
Prior art date
Application number
AT00908771T
Other languages
English (en)
Inventor
Eli Cohen
Peter R Delmenico
Gabriel Ravin
William R George
John A Lake
Original Assignee
Haemoscope Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haemoscope Corp filed Critical Haemoscope Corp
Application granted granted Critical
Publication of ATE280388T1 publication Critical patent/ATE280388T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G01N11/16—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
    • G01N11/162—Oscillations being torsional, e.g. produced by rotating bodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G01N11/16—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
    • G01N11/162—Oscillations being torsional, e.g. produced by rotating bodies
    • G01N11/167—Sample holder oscillates, e.g. rotating crucible

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Telephone Function (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
AT00908771T 1999-02-22 2000-02-22 Verfahren und vorrichtung zur messung von hämostase ATE280388T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/255,099 US6225126B1 (en) 1999-02-22 1999-02-22 Method and apparatus for measuring hemostasis
PCT/US2000/004538 WO2000049402A1 (en) 1999-02-22 2000-02-22 Method and apparatus for measuring hemostasis

Publications (1)

Publication Number Publication Date
ATE280388T1 true ATE280388T1 (de) 2004-11-15

Family

ID=22966839

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03017870T ATE309535T1 (de) 1999-02-22 2000-02-22 Einen probennapf und eine probenspitze aufweisende napfvorrichtung
AT00908771T ATE280388T1 (de) 1999-02-22 2000-02-22 Verfahren und vorrichtung zur messung von hämostase

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT03017870T ATE309535T1 (de) 1999-02-22 2000-02-22 Einen probennapf und eine probenspitze aufweisende napfvorrichtung

Country Status (8)

Country Link
US (2) US6225126B1 (de)
EP (2) EP1371981B1 (de)
JP (1) JP3478333B2 (de)
AT (2) ATE309535T1 (de)
AU (1) AU3005000A (de)
CA (1) CA2362900C (de)
DE (3) DE60015091T2 (de)
WO (1) WO2000049402A1 (de)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225126B1 (en) * 1999-02-22 2001-05-01 Haemoscope Corporation Method and apparatus for measuring hemostasis
US6797519B2 (en) * 2001-10-10 2004-09-28 Haemoscope Corporation Method and apparatus for diagnosing hemostasis
US6613573B1 (en) * 1999-02-22 2003-09-02 Haemoscope Corporation Method and apparatus for monitoring anti-platelet agents
US8076144B2 (en) * 1999-02-22 2011-12-13 Cora Healthcare, Inc. Protocol for risk stratification of ischemic events and optimized individualized treatment
US7732213B2 (en) * 1999-02-22 2010-06-08 Coramed Healthcare, Inc. Method of evaluating patient hemostasis
US6787363B2 (en) * 1999-02-22 2004-09-07 Haemoscope Corporation Method and apparatus for hemostasis and blood management
US8008086B2 (en) * 1999-02-22 2011-08-30 Cora Healthcare, Inc. Protocol for monitoring direct thrombin inhibition
US7179652B2 (en) * 1999-02-22 2007-02-20 Haemoscope Corporation Protocol for monitoring platelet inhibition
US6989272B1 (en) * 2001-03-06 2006-01-24 David Varon Apparatus and method for processing and testing a biological specimen
AU2003226075B2 (en) * 2002-04-12 2008-09-25 Instrumentation Laboratory Company Immunoassay probe
US6890299B2 (en) * 2003-04-08 2005-05-10 Haemoscope Corporation Method and apparatus for monitoring hemostasis in connection with artificial surface devices
US7524670B2 (en) * 2003-08-05 2009-04-28 Haemoscope Corporation Protocol and apparatus for determining heparin-induced thrombocytopenia
US7892188B2 (en) * 2003-10-22 2011-02-22 Hemosonics, Llc Method and apparatus for characterization of clot formation
US8211386B2 (en) 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
GB0418474D0 (en) 2004-08-12 2004-09-22 Pentapharm Ltd Device with novel and improved surface properties
US7745223B2 (en) * 2004-08-12 2010-06-29 C A Casyso Ag Device with novel and improved surface properties
US7544514B2 (en) * 2004-12-27 2009-06-09 David Varon Method and system for determining platelet-mediated clot formation
US20070059840A1 (en) * 2005-05-16 2007-03-15 Haemoscope Corporation Hemostasis Analysis Device and Method
US20080037363A1 (en) * 2006-08-14 2008-02-14 Michael Joe Brannon Agitation system and method for measuring settling rate of solids from a suspension
US7949498B2 (en) * 2006-10-02 2011-05-24 University Of Virginia Patent Foundation Method, system and computer program product for registration of multi-dimensional datasets
US20080114549A1 (en) * 2006-11-09 2008-05-15 Mark Evan Schafer Rapid response blood analyzer
GB2444956A (en) 2006-12-19 2008-06-25 Pentapharm Ag An apparatus and method for measuring the coagulation characteristics of a test liquid
GB0701821D0 (en) * 2007-02-01 2007-03-14 Pentapharm Ag Diagnostic composition and its use in the determination of coagulation characteristics of a test liquid
EP2202517B1 (de) 2008-12-23 2012-08-08 C A Casyso AG Kartuschenvorrichtung für ein Messsystem zur Messung der viskoelastischen Eigenschaften einer Probenflüssigkeit, zugehöriges Messsystem und zugehöriges Verfahren
US8448499B2 (en) 2008-12-23 2013-05-28 C A Casyso Ag Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method
US8383045B2 (en) * 2009-01-16 2013-02-26 C A Casyso Ag Measuring unit for measuring characteristics of a sample liquid, in particular viscoelastic characteristics of a blood sample
RU2430380C2 (ru) * 2009-12-10 2011-09-27 Государственное образовательное учреждение высшего профессионального образования "Тамбовский государственный технический университет" ГОУ ВПО ТГТУ Способ определения функционального состояния системы гемостаза
EP2371284A1 (de) 2010-03-24 2011-10-05 C A Casyso AG Verfahren und Vorrichtung zur Bestimmung von mindestens einem Auswertungsparameter einer Blutprobe
KR20130010483A (ko) 2010-03-30 2013-01-28 씨 에이 카시소 아게 검사액의 응고 특성의 측정을 위한 조성물
ES2739038T3 (es) 2010-04-08 2020-01-28 Hemosonics Llc Visualización de parámetros hemostáticos
CN103649751B (zh) 2011-02-15 2017-03-29 海默索尼克斯有限公司 用于评估止血的装置、系统和方法
AU2012364909B2 (en) * 2011-02-15 2016-11-24 Hemosonics, Llc Characterization of blood hemostasis and oxygen transport parameters
US20120294767A1 (en) 2011-05-19 2012-11-22 Hemosonics Llc Portable hemostasis analyzer
US10266871B2 (en) 2012-12-18 2019-04-23 Daiichi Sankyo Company, Limited Measurement method for thrombin production
US10823743B1 (en) * 2013-10-28 2020-11-03 Ifirst Medical Technologies, Inc. Methods of measuring coagulation of a biological sample
CN104614539A (zh) * 2013-11-05 2015-05-13 北京乐普医疗科技有限责任公司 一种血栓弹力图仪
CN105004868B (zh) * 2014-04-17 2016-08-31 北京乐普医疗科技有限责任公司 一种多通道血栓弹力图仪及使用方法
WO2015171116A1 (en) 2014-05-05 2015-11-12 Haemonetics Corporation Methodologies and reagents for detecting fibrinolysis and hyperfibrinolysis
EP3175245B1 (de) * 2014-07-31 2019-05-29 Haemonetics Corporation Detektion und klassifizierung von antikoagulans unter verwendung eines gerinnungstests
CN104181311B (zh) * 2014-08-22 2016-02-03 中国科学院苏州生物医学工程技术研究所 一种血栓弹力测试装置
US10816559B2 (en) 2014-09-29 2020-10-27 Ca Casyso Ag Blood testing system and method
US10175225B2 (en) 2014-09-29 2019-01-08 C A Casyso Ag Blood testing system and method
US10539579B2 (en) 2014-09-29 2020-01-21 C A Casyso Gmbh Blood testing system and method
US9897618B2 (en) 2014-09-29 2018-02-20 C A Casyso Gmbh Blood testing system
US10288630B2 (en) 2014-09-29 2019-05-14 C A Casyso Gmbh Blood testing system and method
US9726647B2 (en) 2015-03-17 2017-08-08 Hemosonics, Llc Determining mechanical properties via ultrasound-induced resonance
USD777343S1 (en) 2015-05-28 2017-01-24 C A Casyso Ag Body fluid cartridge device
US10295554B2 (en) * 2015-06-29 2019-05-21 C A Casyso Gmbh Blood testing system and method
EP3317422B1 (de) 2015-07-01 2019-08-28 Leyser Lab GmbH Diagnostischer kit für die analyse der viskoelastizität sowie dessen verwendung
WO2017044055A1 (en) 2015-09-08 2017-03-16 Elbuken Caglar Blood coagulation time measurement method and apparatus
WO2017178034A1 (en) 2016-04-15 2017-10-19 Dynabyte Informationssysteme Gmbh Pipette tip and uses and methods thereof
CN106442952B (zh) * 2016-08-30 2019-02-12 诺泰科生物科技（苏州）有限公司 一种血栓弹力仪及其校准方法
WO2017186186A1 (zh) * 2016-04-29 2017-11-02 诺泰科生物科技（苏州）有限公司 一种血栓弹力仪及检测旋转轴转动角度的方法
JP6924257B2 (ja) 2016-04-29 2021-08-25 ネオテック バイオサイエンス カンパニー リミテッド 蓋取外し装置及び該装置を備えたトロンボエラストグラフ
US11366094B2 (en) * 2016-04-29 2022-06-21 Haemonetics Corporation Thrombelastography device, heating apparatus, blood coagulation analysis system and rotational angle measurement method
WO2017186184A1 (zh) * 2016-04-29 2017-11-02 诺泰科生物科技（苏州）有限公司 一种检测血凝数据的装置
US10801939B2 (en) 2016-04-29 2020-10-13 Neotek Bioscience Co., Ltd. Apparatus for measuring blood coagulation data and use method thereof, connection member and support
CN105807039B (zh) * 2016-04-29 2018-11-23 诺泰科生物科技（苏州）有限公司 血栓弹力仪
CN106153877B (zh) * 2016-06-20 2019-05-07 长春理工大学 溶液相变动态分析装置及测试方法
CN107525915B (zh) * 2016-06-21 2019-10-18 北京航空航天大学 一种血栓弹力图仪
CN109642909B (zh) * 2016-08-29 2022-06-03 藤森工业株式会社 血液凝固检查装置以及血液凝固检查方法
US10473674B2 (en) 2016-08-31 2019-11-12 C A Casyso Gmbh Controlled blood delivery to mixing chamber of a blood testing cartridge
US11596948B2 (en) 2016-11-17 2023-03-07 Enicor Gmbh Coated articles for blood coagulation testing and methods of preparing the same
CN113776989A (zh) 2017-01-26 2021-12-10 埃尼科尔股份有限公司 用于测量样本的粘弹性变化的设备和方法
ES2991730T3 (es) 2017-04-20 2024-12-04 Hemosonics Llc Sistema desechable para el análisis de la función hemostática
CN106970237B (zh) * 2017-05-15 2018-08-17 深圳麦科田生物医疗技术有限公司 一种装卸杯装置及血栓弹力图仪
US10843185B2 (en) 2017-07-12 2020-11-24 Ca Casyso Gmbh Autoplatelet cartridge device
CN107505471B (zh) * 2017-09-06 2023-11-28 中国科学院苏州生物医学工程技术研究所 血栓弹力测试装置
CN107843525A (zh) * 2017-11-27 2018-03-27 世纪亿康（天津）医疗科技发展有限公司 检测凝血功能的样品杯及其应用
CN107957499B (zh) * 2018-01-12 2024-09-24 宝锐生物科技泰州有限公司 血栓弹力图仪
CN110389210B (zh) * 2019-07-02 2024-03-22 中国科学院苏州生物医学工程技术研究所 凝血测试装置
CN110389211B (zh) * 2019-07-02 2024-03-22 中国科学院苏州生物医学工程技术研究所 血液动力学检测装置
WO2021154995A1 (en) 2020-01-29 2021-08-05 Ifirst Medical Technologies, Inc. Medical analyzer and diagnostic sample profiler
CN111707814B (zh) * 2020-07-16 2023-11-07 广州万孚生物技术股份有限公司 一种血栓弹力分析装置及方法
CN113985043B (zh) * 2021-10-27 2025-05-13 阳普医疗科技股份有限公司 一种血栓弹力图仪

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053078A (en) 1958-04-17 1962-09-11 Warren R Jewett Apparatus for testing biological and other fluids
DE2019341C3 (de) * 1970-04-22 1979-12-20 Dr. Eduard Fresenius Chemisch-Pharmazeutische Industrie Kg, 6380 Bad Homburg Einrichtung zur Simulierung von Strömungswirkungen in einer gerinnenden Flüssigkeit, insbesondere in Blut
IT1076740B (it) 1977-04-28 1985-04-27 E L V I Spa Apparecchiatura per la determinazione dei parametri di elasticita' del sangue
DE2741060C2 (de) * 1977-09-13 1982-06-24 Chemisch-pharmazeutische Industrie KG 6380 Bad Homburg Dr. Eduard Fresenius Verfahren und Vorrichtung zur Erfassung der Zustandsänderung einer Flüssigkeit
US4148216A (en) * 1978-01-18 1979-04-10 Do Mau T Apparatus for determining the viscous behavior of a liquid during coagulation thereof
FR2455273A2 (fr) * 1979-04-27 1980-11-21 Probio Dms Perfectionnements apportes aux dispositifs de thromboelastographie
US4317363A (en) * 1980-06-16 1982-03-02 Abbott Laboratories Elastomer instrument
US4695956A (en) * 1984-11-01 1987-09-22 Leveen Eric G Apparatus and method of quantifying hemostasis using oscillations from a transducer immersed in the blood sample
DE3738901A1 (de) 1987-11-17 1989-05-24 Amelung Gmbh Heinrich Vorrichtung zur erfassung der zustandsaenderung einer fluessigkeit
US5223227A (en) * 1989-06-19 1993-06-29 Haemoscope Corporation Disposable pin and cup with reuseable stem and collar for blood coagulation analyzer
CA2018788A1 (en) 1989-06-19 1990-12-19 Leon Zuckerman Disposable pin and cup with reuseable stem and collar for blood coagulation analyzer
IL106330A (en) * 1993-07-14 1998-01-04 Univ Ramot Method and instrument for determining the activity of their plaques in the initial coagulation system
EP0734524B1 (de) * 1994-10-19 1997-05-21 Alexander Calatzis Vorrichtung zum messen der koagulationseigenschaften von test-flüssigkeiten
US5854423A (en) 1996-03-20 1998-12-29 Venegas; Jose G. Apparatus and method for assessment of visco-elasticity and shear adherence strength properties of blood clots
US6225126B1 (en) * 1999-02-22 2001-05-01 Haemoscope Corporation Method and apparatus for measuring hemostasis

Also Published As

Publication number Publication date
DE60023957T2 (de) 2006-05-24
CA2362900C (en) 2005-11-29
EP1157273B1 (de) 2004-10-20
EP1371981A1 (de) 2003-12-17
JP3478333B2 (ja) 2003-12-15
ATE309535T1 (de) 2005-11-15
JP2002537560A (ja) 2002-11-05
US6537819B2 (en) 2003-03-25
EP1371981B1 (de) 2005-11-09
DE60015091D1 (de) 2004-11-25
US6225126B1 (en) 2001-05-01
DE20023639U1 (de) 2005-04-07
DE60015091T2 (de) 2005-03-24
WO2000049402A1 (en) 2000-08-24
US20010053552A1 (en) 2001-12-20
CA2362900A1 (en) 2000-08-24
DE60023957D1 (de) 2005-12-15
EP1157273A1 (de) 2001-11-28
AU3005000A (en) 2000-09-04

Similar Documents

Publication Publication Date Title
DE60015091D1 (de) Verfahren und vorrichtung zur messung von hämostase
ATE347096T1 (de) Verfahren und vorrichtung zum ermitteln von schäden an sich zyklisch bewegenden maschinenelementen
DE68923800D1 (de) Vorrichtung und verfahren zur bestimmung eines analyten in einer flüssigen probe mittels folgereaktionen.
ATE556645T1 (de) Konsolidierte körperflüssigkeits-testvorrichtung und verfahren
DE60306711D1 (de) Verfahren und Vorrichtung zur Sammlung von physiologischen Proben
ATE117800T1 (de) Vorrichtung und verfahren zur bestimmung eines bestandteiles in einer flüssigkeitsprobe.
ATE252233T1 (de) Verfahren zur messung von gaskonzentrationen und mikrohergestellter sensor dafür
DE19781863T1 (de) Lanzette für die Gewinnung von Kapillarpunktions-Blutproben
WO2005001418A3 (en) Method and apparatus for body fluid sampling and analyte sensing
ATE232606T1 (de) Verfahren und vorrichtung zum nachweis von hämolysis in flüssigen proben
DK1077634T3 (da) Monitorering af fysiologiske analytter
EE9700163A (et) Diagnostiline testkandja, selle kasutamine ja meetod vedeliku analüüdi määramiseks
DE68922874D1 (de) Verfahren und Gerät zur Blutdruckmessung.
DE3587187D1 (de) Verfahren und vorrichtung zur messung der rheologischen eigenschaften eines biologischen fluidums wie blut.
EP1287839A3 (de) Messvorrichtung und -verfahren zur Bestimmung von Parametern medizinischer Flüssigkeiten
DE3884946D1 (de) Verfahren und Vorrichtung zur automatischen Blutdruckmessung.
DE60035628D1 (de) Verfahren zur Bestimmung des Reaktionsgrades einer Agglutination
DE68925075D1 (de) Mittel und Verfahren zur Analyse
ES542287A0 (es) Un metodo para detectar una secuencia de polinucleotidos en un analito
DE3884948D1 (de) Verfahren und Vorrichtung zur automatischen Blutdruckmessung.
IT8423926A0 (it) Metodo diagnostico per la valutazione di parametri clinici mediante prelievo diretto dimateriali biologici e dispositivoper la sua attuazione.
DE3750745D1 (de) Verfahren und Gerät zur Messung des systolischen Blutdrucks.
ATE373829T1 (de) Lipidassay-verfahren und reagenz zur verwendung darin
DE69013072D1 (de) Gerät zur Analyse von Bestandteilen von Messflüssigkeiten.
ATE182987T1 (de) Nachweisverfahren und vorrichtung dafür

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties