ATE280434T1 - Massenspektrometrie verfahren unter verwendung zusatslicher wechselspannungssignale - Google Patents
Massenspektrometrie verfahren unter verwendung zusatslicher wechselspannungssignaleInfo
- Publication number
- ATE280434T1 ATE280434T1 AT92919964T AT92919964T ATE280434T1 AT E280434 T1 ATE280434 T1 AT E280434T1 AT 92919964 T AT92919964 T AT 92919964T AT 92919964 T AT92919964 T AT 92919964T AT E280434 T1 ATE280434 T1 AT E280434T1
- Authority
- AT
- Austria
- Prior art keywords
- ions
- low power
- component
- trap
- mass spectrometry
- Prior art date
Links
- 238000004949 mass spectrometry Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 150000002500 ions Chemical class 0.000 abstract 7
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 238000010494 dissociation reaction Methods 0.000 abstract 3
- 230000005593 dissociations Effects 0.000 abstract 3
- 230000000153 supplemental effect Effects 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000005040 ion trap Methods 0.000 abstract 1
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
- H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
- H01J49/0063—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by applying a resonant excitation voltage
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/4205—Device types
- H01J49/424—Three-dimensional ion traps, i.e. comprising end-cap and ring electrodes
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/426—Methods for controlling ions
- H01J49/427—Ejection and selection methods
- H01J49/4285—Applying a resonant signal, e.g. selective resonant ejection matching the secular frequency of ions
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electron Tubes For Measurement (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/753,325 US5200613A (en) | 1991-02-28 | 1991-08-30 | Mass spectrometry method using supplemental AC voltage signals |
| PCT/US1992/007345 WO1993005533A1 (en) | 1991-08-30 | 1992-08-28 | Mass spectrometry method using supplemental ac voltage signals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE280434T1 true ATE280434T1 (de) | 2004-11-15 |
Family
ID=25030166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92919964T ATE280434T1 (de) | 1991-08-30 | 1992-08-28 | Massenspektrometrie verfahren unter verwendung zusatslicher wechselspannungssignale |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5200613A (de) |
| EP (1) | EP0601118B1 (de) |
| JP (1) | JP3038917B2 (de) |
| AT (1) | ATE280434T1 (de) |
| CA (1) | CA2116344C (de) |
| DE (1) | DE69233438T2 (de) |
| WO (1) | WO1993005533A1 (de) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5451782A (en) * | 1991-02-28 | 1995-09-19 | Teledyne Et | Mass spectometry method with applied signal having off-resonance frequency |
| US5381007A (en) * | 1991-02-28 | 1995-01-10 | Teledyne Mec A Division Of Teledyne Industries, Inc. | Mass spectrometry method with two applied trapping fields having same spatial form |
| US5206507A (en) * | 1991-02-28 | 1993-04-27 | Teledyne Mec | Mass spectrometry method using filtered noise signal |
| US5274233A (en) * | 1991-02-28 | 1993-12-28 | Teledyne Mec | Mass spectrometry method using supplemental AC voltage signals |
| US5134286A (en) * | 1991-02-28 | 1992-07-28 | Teledyne Cme | Mass spectrometry method using notch filter |
| US5436445A (en) * | 1991-02-28 | 1995-07-25 | Teledyne Electronic Technologies | Mass spectrometry method with two applied trapping fields having same spatial form |
| DE69321165T2 (de) * | 1992-05-29 | 1999-06-02 | Varian Associates, Inc., Palo Alto, Calif. | Verfahren zur Verwendung eines Massenspektrometers |
| US5404011A (en) * | 1992-05-29 | 1995-04-04 | Varian Associates, Inc. | MSn using CID |
| US5457315A (en) * | 1994-01-11 | 1995-10-10 | Varian Associates, Inc. | Method of selective ion trapping for quadrupole ion trap mass spectrometers |
| US5381006A (en) * | 1992-05-29 | 1995-01-10 | Varian Associates, Inc. | Methods of using ion trap mass spectrometers |
| US5479012A (en) * | 1992-05-29 | 1995-12-26 | Varian Associates, Inc. | Method of space charge control in an ion trap mass spectrometer |
| DE4316737C1 (de) * | 1993-05-19 | 1994-09-01 | Bruker Franzen Analytik Gmbh | Verfahren zur digitalen Erzeugung einer zusätzlichen Wechselspannung für die resonante Anregung von Ionen in Ionenfallen |
| DE4316738C2 (de) * | 1993-05-19 | 1996-10-17 | Bruker Franzen Analytik Gmbh | Auswurf von Ionen aus Ionenfallen durch kombinierte elektrische Dipol- und Quadrupolfelder |
| ATE188139T1 (de) | 1993-06-28 | 2000-01-15 | Shimadzu Corp | Quadrupol mit einem von der resonanzfrequenz abweichenden angelegten signal |
| DE4324233C1 (de) * | 1993-07-20 | 1995-01-19 | Bruker Franzen Analytik Gmbh | Verfahren zur Auswahl der Reaktionspfade in Ionenfallen |
| DE4425384C1 (de) * | 1994-07-19 | 1995-11-02 | Bruker Franzen Analytik Gmbh | Verfahren zur stoßinduzierten Fragmentierung von Ionen in Ionenfallen |
| US5696376A (en) * | 1996-05-20 | 1997-12-09 | The Johns Hopkins University | Method and apparatus for isolating ions in an ion trap with increased resolving power |
| DE19932839B4 (de) * | 1999-07-14 | 2007-10-11 | Bruker Daltonik Gmbh | Fragmentierung in Quadrupol-Ionenfallenmassenspektrometern |
| JP3470671B2 (ja) * | 2000-01-31 | 2003-11-25 | 株式会社島津製作所 | イオントラップ型質量分析装置における広帯域信号生成方法 |
| WO2002025265A1 (en) * | 2000-09-20 | 2002-03-28 | Hitachi, Ltd. | Probing method using ion trap mass spectrometer and probing device |
| JP4631219B2 (ja) * | 2001-06-26 | 2011-02-16 | 株式会社島津製作所 | イオントラップ型質量分析装置 |
| JPWO2003041116A1 (ja) * | 2001-11-07 | 2005-03-03 | 株式会社日立ハイテクノロジーズ | 質量分析方法及びイオントラップ質量分析計 |
| US6710336B2 (en) | 2002-01-30 | 2004-03-23 | Varian, Inc. | Ion trap mass spectrometer using pre-calculated waveforms for ion isolation and collision induced dissociation |
| US6838665B2 (en) * | 2002-09-26 | 2005-01-04 | Hitachi High-Technologies Corporation | Ion trap type mass spectrometer |
| JP3936908B2 (ja) * | 2002-12-24 | 2007-06-27 | 株式会社日立ハイテクノロジーズ | 質量分析装置及び質量分析方法 |
| WO2005116378A2 (en) * | 2004-05-24 | 2005-12-08 | University Of Massachusetts | Multiplexed tandem mass spectrometry |
| US7772549B2 (en) | 2004-05-24 | 2010-08-10 | University Of Massachusetts | Multiplexed tandem mass spectrometry |
| JP4653972B2 (ja) * | 2004-06-11 | 2011-03-16 | 株式会社日立ハイテクノロジーズ | イオントラップ/飛行時間型質量分析装置および質量分析方法 |
| US7102129B2 (en) * | 2004-09-14 | 2006-09-05 | Thermo Finnigan Llc | High-Q pulsed fragmentation in ion traps |
| US6949743B1 (en) | 2004-09-14 | 2005-09-27 | Thermo Finnigan Llc | High-Q pulsed fragmentation in ion traps |
| US7656236B2 (en) * | 2007-05-15 | 2010-02-02 | Teledyne Wireless, Llc | Noise canceling technique for frequency synthesizer |
| US8334506B2 (en) | 2007-12-10 | 2012-12-18 | 1St Detect Corporation | End cap voltage control of ion traps |
| US8179045B2 (en) * | 2008-04-22 | 2012-05-15 | Teledyne Wireless, Llc | Slow wave structure having offset projections comprised of a metal-dielectric composite stack |
| US7973277B2 (en) | 2008-05-27 | 2011-07-05 | 1St Detect Corporation | Driving a mass spectrometer ion trap or mass filter |
| US8178835B2 (en) * | 2009-05-07 | 2012-05-15 | Thermo Finnigan Llc | Prolonged ion resonance collision induced dissociation in a quadrupole ion trap |
| FR2950697B1 (fr) * | 2009-09-25 | 2011-12-09 | Biomerieux Sa | Procede de detection de molecules par spectrometrie de masse |
| US9202660B2 (en) | 2013-03-13 | 2015-12-01 | Teledyne Wireless, Llc | Asymmetrical slow wave structures to eliminate backward wave oscillations in wideband traveling wave tubes |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4540884A (en) * | 1982-12-29 | 1985-09-10 | Finnigan Corporation | Method of mass analyzing a sample by use of a quadrupole ion trap |
| EP0409362B1 (de) * | 1985-05-24 | 1995-04-19 | Finnigan Corporation | Betriebsverfahren für eine Ionenfalle |
| US4686367A (en) * | 1985-09-06 | 1987-08-11 | Finnigan Corporation | Method of operating quadrupole ion trap chemical ionization mass spectrometry |
| US5107109A (en) * | 1986-03-07 | 1992-04-21 | Finnigan Corporation | Method of increasing the dynamic range and sensitivity of a quadrupole ion trap mass spectrometer |
| US4761545A (en) * | 1986-05-23 | 1988-08-02 | The Ohio State University Research Foundation | Tailored excitation for trapped ion mass spectrometry |
| US4749860A (en) * | 1986-06-05 | 1988-06-07 | Finnigan Corporation | Method of isolating a single mass in a quadrupole ion trap |
| US4771172A (en) * | 1987-05-22 | 1988-09-13 | Finnigan Corporation | Method of increasing the dynamic range and sensitivity of a quadrupole ion trap mass spectrometer operating in the chemical ionization mode |
| DE3886922T2 (de) * | 1988-04-13 | 1994-04-28 | Bruker Franzen Analytik Gmbh | Methode zur Massenanalyse einer Probe mittels eines Quistors und zur Durchführung dieses Verfahrens entwickelter Quistor. |
| EP0362432A1 (de) * | 1988-10-07 | 1990-04-11 | Bruker Franzen Analytik GmbH | Methode zur Massenanalyse einer Probe |
| ATE101942T1 (de) * | 1989-02-18 | 1994-03-15 | Bruker Franzen Analytik Gmbh | Verfahren und geraet zur massenbestimmung von proben mittels eines quistors. |
| US5075547A (en) * | 1991-01-25 | 1991-12-24 | Finnigan Corporation | Quadrupole ion trap mass spectrometer having two pulsed axial excitation input frequencies and method of parent and neutral loss scanning and selected reaction monitoring |
| CA2101152C (en) * | 1991-02-28 | 1999-03-30 | Paul E. Kelley | Mass spectrometry method using supplemental ac voltage signals |
| US5134286A (en) * | 1991-02-28 | 1992-07-28 | Teledyne Cme | Mass spectrometry method using notch filter |
-
1991
- 1991-08-30 US US07/753,325 patent/US5200613A/en not_active Expired - Lifetime
-
1992
- 1992-08-28 WO PCT/US1992/007345 patent/WO1993005533A1/en not_active Ceased
- 1992-08-28 EP EP92919964A patent/EP0601118B1/de not_active Expired - Lifetime
- 1992-08-28 AT AT92919964T patent/ATE280434T1/de not_active IP Right Cessation
- 1992-08-28 JP JP05505338A patent/JP3038917B2/ja not_active Expired - Lifetime
- 1992-08-28 CA CA002116344A patent/CA2116344C/en not_active Expired - Lifetime
- 1992-08-28 DE DE69233438T patent/DE69233438T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07502138A (ja) | 1995-03-02 |
| DE69233438T2 (de) | 2005-03-03 |
| DE69233438D1 (de) | 2004-11-25 |
| CA2116344A1 (en) | 1993-03-18 |
| WO1993005533A1 (en) | 1993-03-18 |
| JP3038917B2 (ja) | 2000-05-08 |
| US5200613A (en) | 1993-04-06 |
| EP0601118A4 (en) | 1995-08-23 |
| EP0601118A1 (de) | 1994-06-15 |
| EP0601118B1 (de) | 2004-10-20 |
| CA2116344C (en) | 2002-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |