ATE280574T1 - PLASTER CONTAINING ISOSORBIDE DINITRATE - Google Patents

PLASTER CONTAINING ISOSORBIDE DINITRATE

Info

Publication number
ATE280574T1
ATE280574T1 AT98900046T AT98900046T ATE280574T1 AT E280574 T1 ATE280574 T1 AT E280574T1 AT 98900046 T AT98900046 T AT 98900046T AT 98900046 T AT98900046 T AT 98900046T AT E280574 T1 ATE280574 T1 AT E280574T1
Authority
AT
Austria
Prior art keywords
isosorbide dinitrate
adhesive composition
adhesive
weight
component
Prior art date
Application number
AT98900046T
Other languages
German (de)
Inventor
Osafumi Hidaka
Satoshi Murakami
Yoshifusa Tachimori
Michisuke Ohe
Original Assignee
Teijin Ltd
Teysan Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd, Teysan Pharmaceuticals Co Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of ATE280574T1 publication Critical patent/ATE280574T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to an isosorbide dinitrate-containing patch, in which an adhesive layer comprising an adhesive composition is formed on a flexible support, and the adhesive composition consists of an acrylic-based adhesive (A), a polyvinyl acetate-based adhesive (B), a plasticizing component (C) and isosorbide dinitrate (D), and satisfies the following weight ratios (1) through (3) of each of the components: (1) A:B = 70:30 to 10:90, (2) the weight ratio of the component C based on the adhesive composition is 10 to 40% by weight, and (3) the weight ratio of the component D based on the adhesive composition is 20 to 35% by weight. Provided is a patch excellent in percutaneous absorption, handleability, resistance to skin irritation, sustained release, adhesivity, etc. <IMAGE>
AT98900046T 1997-01-07 1998-01-06 PLASTER CONTAINING ISOSORBIDE DINITRATE ATE280574T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP65197 1997-01-07
JP26164597 1997-09-26
PCT/JP1998/000009 WO1998030210A1 (en) 1997-01-07 1998-01-06 Patch containing isosorbide dinitrate

Publications (1)

Publication Number Publication Date
ATE280574T1 true ATE280574T1 (en) 2004-11-15

Family

ID=26333670

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98900046T ATE280574T1 (en) 1997-01-07 1998-01-06 PLASTER CONTAINING ISOSORBIDE DINITRATE

Country Status (13)

Country Link
US (1) US6319515B1 (en)
EP (1) EP0900565B1 (en)
JP (1) JP3865787B2 (en)
KR (1) KR100337962B1 (en)
CN (1) CN1102384C (en)
AT (1) ATE280574T1 (en)
AU (1) AU735387B2 (en)
CA (1) CA2248167C (en)
DE (1) DE69827210T2 (en)
ES (1) ES2230666T3 (en)
NZ (1) NZ332192A (en)
TW (1) TW577750B (en)
WO (1) WO1998030210A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7365900A (en) 1999-09-08 2001-04-10 Nitromed, Inc. Methods of treating and preventing congestive heart failure with hydralazine compounds and isosorbide dinitrate or isosorbide mononitrate
US7708989B2 (en) * 1999-10-29 2010-05-04 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
US6635273B1 (en) 1999-10-29 2003-10-21 Trustees Of Boston University Methods of treating vascular diseases characterized by nitric oxide insufficiency
US7537785B2 (en) * 1999-10-29 2009-05-26 Nitromed, Inc. Composition for treating vascular diseases characterized by nitric oxide insufficiency
US7235237B2 (en) * 1999-10-29 2007-06-26 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
WO2001066095A1 (en) * 2000-03-07 2001-09-13 Teijin Limited Stretchable patch
JP5021124B2 (en) * 2001-08-29 2012-09-05 日東電工株式会社 Medical adhesive composition, medical adhesive tape and transdermal absorption tape formulation using the same
DE10341933A1 (en) * 2003-09-11 2005-04-14 Lts Lohmann Therapie-Systeme Ag Medicated skin patches containing essential oils for the treatment of colds and methods of making the same
USD537947S1 (en) * 2004-06-10 2007-03-06 Hisamitsu Pharmaceutical Co., Inc. Medical patch
US20060014828A1 (en) * 2004-07-16 2006-01-19 Nitromed, Inc. Compositions and methods related to heart failure
USD545441S1 (en) * 2004-12-01 2007-06-26 Hisamitsu Pharmaceutical Co., Inc. Medical patch
JP2006288887A (en) * 2005-04-13 2006-10-26 Nitto Denko Corp Patch preparation
WO2007065303A1 (en) * 2005-12-09 2007-06-14 Beijing Kangbeide Pharmaceutical Technology Development Co., Ltd. Transdermal patch containing isosorbide dinitrate and bisoprolol
AU2007217980A1 (en) * 2006-02-17 2007-08-30 Nitromed, Inc. Methods using hydralazine compounds and isosorbide dinitrate or isosorbide mononitrate
AU2007254283A1 (en) * 2006-05-16 2007-11-29 Nitromed, Inc. Solid dosage formulations of hydralazine compounds
JP5237112B2 (en) * 2006-12-01 2013-07-17 日東電工株式会社 Transdermal absorption preparation
KR101408488B1 (en) * 2006-12-01 2014-06-17 닛토덴코 가부시키가이샤 Method for prevention of discoloration with time of donepezil-containing skin adhesive preparation
JP5235384B2 (en) * 2007-11-08 2013-07-10 リンテック株式会社 Attached sheet
RU2483729C2 (en) * 2008-05-30 2013-06-10 Нитто Денко Корпорейшн Percutaneously absorbable preparation
EP2279739B2 (en) † 2008-05-30 2018-02-28 Nitto Denko Corporation Donepezil-containing patch preparation and packaging thereof
JP2010163367A (en) * 2009-01-13 2010-07-29 Nitto Denko Corp Patch and patch preparation
CA2807065A1 (en) * 2010-07-29 2012-02-02 Santen Pharmaceutical Co., Ltd. Drug support body, and method for producing same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57116011A (en) 1981-01-08 1982-07-19 Nitto Electric Ind Co Ltd Pharmaceutical preparation
EP0223524B1 (en) * 1985-11-08 1991-10-23 Nitto Denko Corporation Use of adhesive dermal bandages and dermal percutaneous preparations
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
ES2055291T5 (en) * 1989-12-28 2000-03-01 Nitto Denko Corp ACRYLIC GEL MATERIAL AND ACRYLIC GEL PREPARATION.
JP3223212B2 (en) 1993-04-28 2001-10-29 ライオン株式会社 Detergent composition
JP2945244B2 (en) 1993-05-24 1999-09-06 帝三製薬株式会社 Patch containing isosorbide dinitrate using vinyl acetate adhesive
JP3081413B2 (en) 1993-06-03 2000-08-28 帝三製薬株式会社 Method for producing patch containing isosorbide dinitrate using mixed adhesive
ES2122140T3 (en) * 1993-12-30 1998-12-16 Rotta Res Bv TRANSDERMIC PATCH WITH ISOSORBIDE DINITRATE AS AN ACTIVE INGREDIENT.
CA2184389A1 (en) 1994-02-28 1995-08-31 Takao Fujii Patch containing isosorbide dinitrate and prepared by using adhesive mixture

Also Published As

Publication number Publication date
EP0900565A4 (en) 2001-01-03
KR100337962B1 (en) 2002-10-25
EP0900565B1 (en) 2004-10-27
ES2230666T3 (en) 2005-05-01
CA2248167C (en) 2004-02-03
KR20000064560A (en) 2000-11-06
AU7994498A (en) 1998-08-03
CN1102384C (en) 2003-03-05
TW577750B (en) 2004-03-01
CN1217656A (en) 1999-05-26
NZ332192A (en) 1999-02-25
US6319515B1 (en) 2001-11-20
CA2248167A1 (en) 1998-07-16
DE69827210T2 (en) 2006-03-09
AU735387B2 (en) 2001-07-05
JP3865787B2 (en) 2007-01-10
WO1998030210A1 (en) 1998-07-16
EP0900565A1 (en) 1999-03-10
DE69827210D1 (en) 2004-12-02

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