ATE280578T1 - Kombination von einem den retinoinsäure metabolismus blockierenden arzneimittel und einem tocopherol - Google Patents
Kombination von einem den retinoinsäure metabolismus blockierenden arzneimittel und einem tocopherolInfo
- Publication number
- ATE280578T1 ATE280578T1 AT98966615T AT98966615T ATE280578T1 AT E280578 T1 ATE280578 T1 AT E280578T1 AT 98966615 T AT98966615 T AT 98966615T AT 98966615 T AT98966615 T AT 98966615T AT E280578 T1 ATE280578 T1 AT E280578T1
- Authority
- AT
- Austria
- Prior art keywords
- tocopherol
- combination
- retinoic acid
- acid metabolism
- metabolism blocking
- Prior art date
Links
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 3
- 229930003799 tocopherol Natural products 0.000 title abstract 2
- 229960001295 tocopherol Drugs 0.000 title abstract 2
- 239000011732 tocopherol Substances 0.000 title abstract 2
- 235000010384 tocopherol Nutrition 0.000 title abstract 2
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 title abstract 2
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 title 1
- 230000000903 blocking effect Effects 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 230000004060 metabolic process Effects 0.000 title 1
- 229930002330 retinoic acid Natural products 0.000 title 1
- 229960001727 tretinoin Drugs 0.000 title 1
- 229930003427 Vitamin E Natural products 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 150000001448 anilines Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000012440 retinoic acid metabolism blocking agent Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 239000011709 vitamin E Substances 0.000 abstract 1
- 229940046009 vitamin E Drugs 0.000 abstract 1
- 235000019165 vitamin E Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97204019 | 1997-12-19 | ||
| PCT/EP1998/008127 WO1999032098A2 (en) | 1997-12-19 | 1998-12-12 | Combination of a ramba and a tocopherol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE280578T1 true ATE280578T1 (de) | 2004-11-15 |
Family
ID=8229088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98966615T ATE280578T1 (de) | 1997-12-19 | 1998-12-12 | Kombination von einem den retinoinsäure metabolismus blockierenden arzneimittel und einem tocopherol |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6265425B1 (de) |
| EP (1) | EP1037629B1 (de) |
| JP (1) | JP2001526215A (de) |
| AT (1) | ATE280578T1 (de) |
| AU (1) | AU2413399A (de) |
| DE (1) | DE69827295T2 (de) |
| DK (1) | DK1037629T3 (de) |
| ES (1) | ES2232034T3 (de) |
| PT (1) | PT1037629E (de) |
| SI (1) | SI1037629T1 (de) |
| WO (1) | WO1999032098A2 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| US7636680B2 (en) * | 2001-10-03 | 2009-12-22 | Starmine Corporation | Methods and systems for measuring performance of a security analyst |
| WO2003053411A1 (en) | 2001-12-19 | 2003-07-03 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
| WO2006074147A2 (en) | 2005-01-03 | 2006-07-13 | Myriad Genetics, Inc. | Nitrogen containing bicyclic compounds and therapeutical use thereof |
| CN1984660B (zh) * | 2003-07-03 | 2010-12-15 | 美瑞德生物工程公司 | 作为天冬氨酸特异性半胱氨酸蛋白酶活化剂和细胞程序死亡诱导剂的4-芳基氨基-喹唑啉 |
| US8309562B2 (en) * | 2003-07-03 | 2012-11-13 | Myrexis, Inc. | Compounds and therapeutical use thereof |
| WO2006028970A1 (en) | 2004-09-02 | 2006-03-16 | Cengent Therapeutics, Inc. | Derivatives of thiazole and thiadiazole inhibitors of tyrosine phosphatases |
| US8258145B2 (en) | 2005-01-03 | 2012-09-04 | Myrexis, Inc. | Method of treating brain cancer |
| EP1981343B8 (de) | 2006-01-17 | 2015-06-24 | Stiefel Laboratories, Inc. | Behandlung von entzündungserkrankungen mit triazolverbindungen |
| EP1991530A1 (de) * | 2006-02-21 | 2008-11-19 | Amgen Inc. | Cinnolinderivate als phosphodiesterase-10-hemmer |
| WO2009051213A1 (ja) * | 2007-10-19 | 2009-04-23 | The University Of Tokyo | 白斑治療剤および色素沈着促進方法 |
-
1998
- 1998-12-12 DK DK98966615T patent/DK1037629T3/da active
- 1998-12-12 US US09/581,891 patent/US6265425B1/en not_active Expired - Fee Related
- 1998-12-12 PT PT98966615T patent/PT1037629E/pt unknown
- 1998-12-12 ES ES98966615T patent/ES2232034T3/es not_active Expired - Lifetime
- 1998-12-12 EP EP98966615A patent/EP1037629B1/de not_active Expired - Lifetime
- 1998-12-12 AU AU24133/99A patent/AU2413399A/en not_active Abandoned
- 1998-12-12 DE DE69827295T patent/DE69827295T2/de not_active Expired - Fee Related
- 1998-12-12 SI SI9830728T patent/SI1037629T1/xx unknown
- 1998-12-12 JP JP2000525089A patent/JP2001526215A/ja not_active Withdrawn
- 1998-12-12 WO PCT/EP1998/008127 patent/WO1999032098A2/en not_active Ceased
- 1998-12-12 AT AT98966615T patent/ATE280578T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT1037629E (pt) | 2005-03-31 |
| WO1999032098A3 (en) | 1999-08-19 |
| AU2413399A (en) | 1999-07-12 |
| DE69827295D1 (de) | 2004-12-02 |
| WO1999032098A2 (en) | 1999-07-01 |
| EP1037629B1 (de) | 2004-10-27 |
| DE69827295T2 (de) | 2006-02-09 |
| US6265425B1 (en) | 2001-07-24 |
| DK1037629T3 (da) | 2005-03-07 |
| SI1037629T1 (en) | 2005-04-30 |
| JP2001526215A (ja) | 2001-12-18 |
| ES2232034T3 (es) | 2005-05-16 |
| EP1037629A2 (de) | 2000-09-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0012136A (pt) | Inibidores de reabsorção de norepinefrina altamente seletivos e métodos de uso dos mesmos | |
| ATE280578T1 (de) | Kombination von einem den retinoinsäure metabolismus blockierenden arzneimittel und einem tocopherol | |
| BRPI0411255A (pt) | composto, composição farmacêutica, uso de um composto, métodos de tratar um distúrbio de um paciente, e, processo para a preparação de um composto | |
| NO20001087D0 (no) | Medikament for forlengelse av muskelfunksjon eller behandling av muskelforstyrrelser eller -sykdommer | |
| TR199801180T2 (xx) | Aneljestik etkiye sahip yeni bile�ikler. | |
| AU7031500A (en) | Therapeutic quinazoline compounds | |
| NO20042596L (no) | Inbibitorer av 11-beta-hydroksy steroid dehydrogenase type 1 | |
| WO2004089380A3 (en) | Pharmaceutical use of fused 1,2,4-triazoles | |
| ATE79619T1 (de) | Arzneimittel. | |
| AU2506388A (en) | Azelastine-containing medicaments for application in the nose and/or at the eye | |
| YU49026B (sh) | UPOTREBA 17 Гџ -(N-TERC-BUTILKARBAMOIL)-4-AZA-5-ALFA-ANDROST-1-3-ON ZA PROIZVODNJU LEKA ZA TRETIRANJE ANDROGENE ALOPECIJE | |
| MY123193A (en) | Novel 2-(iminomethyl)amino-phenyl derivatives,preparation,application as medicines and compositions containing same | |
| MXPA05003253A (es) | Nuevos derivados de pirimidinamida y el uso de los mismos. | |
| MY124146A (en) | Novel 2-(iminomethyl) amino-phenyl derivatives, preparation, application as medicines and pharmaceutical compositions containing same | |
| WO1998009599A3 (en) | The new use of dicaffeoylquinic acid for treating hepatitis b and the diseases related with retrovirus, and the new caffeoylquinic acid derivatives | |
| CA2215470A1 (fr) | Composes biaryles heterocycliques, compositions pharmaceutiques et cosmetiques les contenant et utilisations | |
| DE60222383D1 (de) | Medikament zur verabreichung von amifostin und verwandten wirkstoffen | |
| EA200501223A1 (ru) | Терапевтическая система, содержащая амоксициллин и клавулановую кислоту | |
| CA2340734A1 (en) | Optically active pyridyl-4h-1,2,4-oxadiazine derivative and its use in the treatment of vascular diseases | |
| HUP9701284A2 (hu) | 2,3-Benzodiazepin-származékok felhasználása az endogén opioid rendszerrel összefüggő betegségek és állapotok kezelésére, és megelőzésére alkalmas gyógyászati készítmények előállítására | |
| TR199801184T2 (xx) | Analjezik tesirli yeni bile�ikler. | |
| TW349864B (en) | Use of N-(pyridinyl)-1H-indol-a-amines for the preparation of a medicament for the treatment of obsessive-compulsive disorders | |
| SE9800905L (sv) | Ny terapi vid glomerulonefrit | |
| DK1492539T3 (da) | Statin-terapi til forögelse af kognitiv funktion | |
| NO984651L (no) | Anvendelse av benzonaftalenderivater for fremstilling av medikamenter for behandling av sykdommer i sentralnervesystemet |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1037629 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |