ATE281456T1 - Aminotriazolopyridinderivate als adenosinrezeptorliganden - Google Patents

Aminotriazolopyridinderivate als adenosinrezeptorliganden

Info

Publication number
ATE281456T1
ATE281456T1 AT01991804T AT01991804T ATE281456T1 AT E281456 T1 ATE281456 T1 AT E281456T1 AT 01991804 T AT01991804 T AT 01991804T AT 01991804 T AT01991804 T AT 01991804T AT E281456 T1 ATE281456 T1 AT E281456T1
Authority
AT
Austria
Prior art keywords
aminotriazolopyridine
derivatives
receptor ligands
adenosine receptor
adenosine
Prior art date
Application number
AT01991804T
Other languages
English (en)
Inventor
Bernd Brodbeck
Matthias Heinrich Nettekoven
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE281456T1 publication Critical patent/ATE281456T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT01991804T 2000-12-15 2001-12-07 Aminotriazolopyridinderivate als adenosinrezeptorliganden ATE281456T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00127567 2000-12-15
PCT/EP2001/014399 WO2002048145A1 (en) 2000-12-15 2001-12-07 Aminotriazolopyridiine derivatives as adenosine receptor ligands

Publications (1)

Publication Number Publication Date
ATE281456T1 true ATE281456T1 (de) 2004-11-15

Family

ID=8170683

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01991804T ATE281456T1 (de) 2000-12-15 2001-12-07 Aminotriazolopyridinderivate als adenosinrezeptorliganden

Country Status (21)

Country Link
US (1) US6506772B1 (de)
EP (1) EP1347974B1 (de)
JP (1) JP4049672B2 (de)
KR (1) KR100540628B1 (de)
CN (1) CN1221551C (de)
AR (1) AR031799A1 (de)
AT (1) ATE281456T1 (de)
AU (2) AU2002231674B2 (de)
BR (1) BR0116193A (de)
CA (1) CA2437006C (de)
DE (1) DE60106974T2 (de)
DK (1) DK1347974T3 (de)
ES (1) ES2230387T3 (de)
GT (1) GT200100253A (de)
MX (1) MXPA03005334A (de)
PA (1) PA8534701A1 (de)
PE (1) PE20020666A1 (de)
PT (1) PT1347974E (de)
UY (1) UY27074A1 (de)
WO (1) WO2002048145A1 (de)
ZA (1) ZA200304481B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0213172A (pt) * 2001-10-08 2004-09-14 Hoffmann La Roche Amida do ácido 8-amino-[1,2,4]triazolo[1,5-a]piridina-6-carboxìlico
EP1556053A4 (de) * 2002-10-31 2006-04-19 Amgen Inc Entzündungshemmende mittel
UA91341C2 (ru) 2004-07-15 2010-07-26 Амр Текнолоджи, Інк. Арил- и гетероарилзамещенные тетрагидроизохинолины и их применение для блокирования обратного захвата норэпинефрина, допамина и серотонина
AU2007272009A1 (en) * 2006-07-12 2008-01-17 Syngenta Limited Triazolopyridine derivatives as herbicides
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
JP5739415B2 (ja) * 2009-05-12 2015-06-24 ブリストル−マイヤーズ スクウィブ カンパニー （Ｓ）−７−（［１，２，４］トリアゾロ［１，５−ａ］ピリジン−６−イル）−４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロイソキノリンの結晶形態およびその使用
CN102595902B (zh) * 2009-05-12 2015-04-29 阿尔巴尼分子研究公司 7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉及其用途
ES2446971T3 (es) 2009-05-12 2014-03-11 Albany Molecular Research, Inc. Tetrahidroisoquinolinas sustituidas con arilo, heteroarilo, y heterociclo y su uso
WO2013043518A1 (en) 2011-09-22 2013-03-28 Merck Sharp & Dohme Corp. Imidazopyridyl compounds as aldosterone synthase inhibitors
EP2757883B1 (de) * 2011-09-22 2021-01-13 Merck Sharp & Dohme Corp. Triazolopyridylverbindungen als aldosteronsynthasehemmer
WO2020054712A1 (ja) * 2018-09-12 2020-03-19 日本化薬株式会社 有害生物防除剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356894A (en) 1990-05-29 1994-10-18 Rodney Peter W Morpholinyl substituted [1,2,4]-triazolo[1,5-a]triazine as antagonist
GB9226735D0 (en) 1992-12-22 1993-02-17 Ici Plc Azole derivatives
AU2639299A (en) 1998-02-24 1999-09-15 Kyowa Hakko Kogyo Co. Ltd. Remedies/preventives for parkinson's disease
US6355653B1 (en) 1999-09-06 2002-03-12 Hoffmann-La Roche Inc. Amino-triazolopyridine derivatives

Also Published As

Publication number Publication date
KR100540628B1 (ko) 2006-01-11
JP4049672B2 (ja) 2008-02-20
PA8534701A1 (es) 2002-08-26
PE20020666A1 (es) 2002-07-27
ZA200304481B (en) 2004-09-09
GT200100253A (es) 2002-07-31
MXPA03005334A (es) 2004-04-02
AU3167402A (en) 2002-06-24
US6506772B1 (en) 2003-01-14
EP1347974B1 (de) 2004-11-03
AR031799A1 (es) 2003-10-01
UY27074A1 (es) 2002-07-31
AU2002231674B2 (en) 2006-07-06
KR20030061446A (ko) 2003-07-18
CN1486314A (zh) 2004-03-31
JP2004521096A (ja) 2004-07-15
DE60106974T2 (de) 2005-11-03
CA2437006C (en) 2009-10-27
BR0116193A (pt) 2003-09-23
CN1221551C (zh) 2005-10-05
CA2437006A1 (en) 2002-06-20
WO2002048145A1 (en) 2002-06-20
EP1347974A1 (de) 2003-10-01
PT1347974E (pt) 2005-02-28
DK1347974T3 (da) 2005-03-14
DE60106974D1 (de) 2004-12-09
ES2230387T3 (es) 2005-05-01

Similar Documents

Publication Publication Date Title
ATE253067T1 (de) Diazabicyloderivate als nikotin-acetylcholin- rezeptorliganden
DOP2001000220A (es) Derivados de imidazol
CY2011002I1 (el) N-πυρραζολικοι αγωνιστες του α2α υποδοχεα
ATE293618T1 (de) 4, 5, 6, 7-tetrahydroindazolderivate als antitumormittel
DE60130463D1 (de) Pyrimidin-derivate
NO20024766L (no) Etylendiaminderivater
ATE360620T1 (de) Imidazolderivate
PT1303521E (pt) Derivados de tetra-hidro-heterocicloazepinil-pirimidina
ATE306265T1 (de) Benzothiazolderivate als adenosin-rezeptor- liganden
PL373953A1 (en) 7-amino-benzothiazole derivatives as adenosine receptor ligands
DE60114852D1 (de) Chinazolin-derivate als alpha-1 adrenerge antagonisten
DE60137061D1 (de) Platin-verbindungen als antitumorwirkstoffe
ATE334114T1 (de) Substituierte c-cyclohexylmethylamin-derivate
AR028602A1 (es) Derivados de pirrol
DE60305058D1 (de) Imidazoquinoline derivate als adenosine a3 rezeptor liganden
ATE293619T1 (de) Pyridinderivate als nmda-rezeptorliganden
IL162444A0 (en) Triazolo-quinolin derivatives useful as adenosine receptor ligands
AR028282A1 (es) Derivados de aminofenil pirimidona
DE60106974D1 (de) Aminotriazolopyridinderivate als adenosinrezeptorliganden
ATE282021T1 (de) Substituierte aminomethyl-phenyl- cyclohexanderivate
DE60003072D1 (de) Thiazolidindion-derivate als antidiabetika
ATE272045T1 (de) Substituierte 1-aminobutan-3-ol-derivate
DE60214408D1 (de) 5-METHOXY-8-ARYL-i1,2,4öTRIAZOLOi1,5-AöPYRIDINE DERIVATIVE ALS ADENOSIN-REZEPTOR ANTAGONISTEN
PT1246791E (pt) Derivados de aminometilfenilciclo-hexanona
DE60012953D1 (de) 3-amino-2-phenylpiperidinderivate als substanz p antagonisten

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1347974

Country of ref document: EP