ATE282698T1 - Biotin-operon - Google Patents
Biotin-operonInfo
- Publication number
- ATE282698T1 ATE282698T1 AT92402495T AT92402495T ATE282698T1 AT E282698 T1 ATE282698 T1 AT E282698T1 AT 92402495 T AT92402495 T AT 92402495T AT 92402495 T AT92402495 T AT 92402495T AT E282698 T1 ATE282698 T1 AT E282698T1
- Authority
- AT
- Austria
- Prior art keywords
- biotin
- dna sequence
- operon
- biotin operon
- productivity
- Prior art date
Links
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 title abstract 10
- 229960002685 biotin Drugs 0.000 title abstract 5
- 235000020958 biotin Nutrition 0.000 title abstract 5
- 239000011616 biotin Substances 0.000 title abstract 5
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
- 241000588724 Escherichia coli Species 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 108020004705 Codon Proteins 0.000 abstract 1
- 101100218845 Escherichia coli (strain K12) bioH gene Proteins 0.000 abstract 1
- 101150029327 bioB gene Proteins 0.000 abstract 1
- 238000009395 breeding Methods 0.000 abstract 1
- 230000001488 breeding effect Effects 0.000 abstract 1
- 230000000977 initiatory effect Effects 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/185—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system
- C12P17/186—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system containing a 2-oxo-thieno[3,4-d]imidazol nucleus, e.g. Biotin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23514891 | 1991-09-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE282698T1 true ATE282698T1 (de) | 2004-12-15 |
Family
ID=16981766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92402495T ATE282698T1 (de) | 1991-09-13 | 1992-09-11 | Biotin-operon |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5885792A (de) |
| EP (1) | EP0532426B1 (de) |
| KR (1) | KR100250692B1 (de) |
| AT (1) | ATE282698T1 (de) |
| CA (1) | CA2078043C (de) |
| DE (1) | DE69233447T2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0635572A3 (de) | 1993-06-25 | 1995-03-08 | Hoffmann La Roche | Biotinbiosynthese in Bacillus subtilis. |
| WO1997016560A1 (en) * | 1995-11-02 | 1997-05-09 | Takeda Chemical Industries, Ltd. | Microorganism resistant to threonine analogue and production of biotin |
| JP4087919B2 (ja) * | 1996-04-06 | 2008-05-21 | ディーエスエム アイピー アセッツ ビー．ブイ． | ｄ−ビオチンの発酵による製造 |
| US7743783B2 (en) * | 2006-04-04 | 2010-06-29 | Air Liquide Electronics U.S. Lp | Method and apparatus for recycling process fluids |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1317245C (en) * | 1985-08-26 | 1993-05-04 | Eric F. Fisher | System for biotin synthesis |
| JPS62155081A (ja) * | 1985-12-27 | 1987-07-10 | Shiseido Co Ltd | 新規微生物およびそれを用いる醗酵法によるビオチンの製造法 |
| CA1322735C (en) * | 1987-11-07 | 1993-10-05 | Shinichiro Haze | Microorganism having low acetate forming capability, and process for production of useful substrate using same |
| GB2216530B (en) * | 1988-03-22 | 1992-07-08 | Mini Agriculture & Fisheries | Genetic material for expression of biotin synthetase enzymes |
-
1992
- 1992-09-09 KR KR1019920016532A patent/KR100250692B1/ko not_active Expired - Fee Related
- 1992-09-11 EP EP92402495A patent/EP0532426B1/de not_active Expired - Lifetime
- 1992-09-11 AT AT92402495T patent/ATE282698T1/de not_active IP Right Cessation
- 1992-09-11 CA CA002078043A patent/CA2078043C/en not_active Expired - Fee Related
- 1992-09-11 DE DE69233447T patent/DE69233447T2/de not_active Expired - Fee Related
- 1992-09-14 US US07/944,259 patent/US5885792A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0532426B1 (de) | 2004-11-17 |
| KR100250692B1 (ko) | 2000-04-01 |
| US5885792A (en) | 1999-03-23 |
| CA2078043A1 (en) | 1993-03-14 |
| CA2078043C (en) | 2003-05-20 |
| DE69233447T2 (de) | 2005-04-07 |
| EP0532426A3 (de) | 1994-08-03 |
| DE69233447D1 (de) | 2004-12-23 |
| KR930006156A (ko) | 1993-04-20 |
| EP0532426A2 (de) | 1993-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |