ATE284878T1 - Pharmazeutische verbindungen mit serotonin rezeptor aktivität - Google Patents

Pharmazeutische verbindungen mit serotonin rezeptor aktivität

Info

Publication number
ATE284878T1
ATE284878T1 AT02746452T AT02746452T ATE284878T1 AT E284878 T1 ATE284878 T1 AT E284878T1 AT 02746452 T AT02746452 T AT 02746452T AT 02746452 T AT02746452 T AT 02746452T AT E284878 T1 ATE284878 T1 AT E284878T1
Authority
AT
Austria
Prior art keywords
receptor activity
pharmaceutical compounds
serotonin receptor
compounds
serotonin
Prior art date
Application number
AT02746452T
Other languages
English (en)
Inventor
Jeremy Gilmore
Carlos Lamas-Peteira
Varela Maria Alicia Li Torrado
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE284878T1 publication Critical patent/ATE284878T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02746452T 2001-07-11 2002-06-27 Pharmazeutische verbindungen mit serotonin rezeptor aktivität ATE284878T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36161101P 2001-07-11 2001-07-11
EP01500181 2001-07-11
PCT/US2002/016594 WO2003006455A1 (en) 2001-07-11 2002-06-27 Pharmaceutical compounds with serotonin receptor activity

Publications (1)

Publication Number Publication Date
ATE284878T1 true ATE284878T1 (de) 2005-01-15

Family

ID=56290307

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02746452T ATE284878T1 (de) 2001-07-11 2002-06-27 Pharmazeutische verbindungen mit serotonin rezeptor aktivität

Country Status (3)

Country Link
EP (1) EP1409476B1 (de)
AT (1) ATE284878T1 (de)
WO (1) WO2003006455A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05001631A (es) 2002-08-12 2005-08-19 Takeda Pharmaceutical Derivado de benceno fusionado y su uso.
KR100553398B1 (ko) * 2004-03-12 2006-02-16 한미약품 주식회사 티에노[3,2-c]피리딘 유도체의 제조 방법 및 이에사용되는 중간체
CA2781716A1 (en) 2009-12-04 2011-06-09 Sunovion Pharmaceuticals Inc. Multicyclic thieno compounds and use thereof for the treatment of a neurological disorder
AU2017301769B2 (en) 2016-07-29 2022-07-28 Pgi Drug Discovery Llc Compounds and compositions and uses thereof
SG10202100751YA (en) 2016-07-29 2021-03-30 Sunovion Pharmaceuticals Inc Compounds and compositions and uses thereof
AU2018220509B2 (en) 2017-02-16 2022-04-28 Sumitomo Pharma America, Inc. Methods of treating schizophrenia
SG11202000669VA (en) 2017-08-02 2020-02-27 Sunovion Pharmaceuticals Inc Isochroman compounds and uses thereof
CA3091292A1 (en) 2018-02-16 2019-08-22 Sunovion Pharmaceuticals Inc. Salts, crystal forms, and production methods thereof
JP7703449B2 (ja) 2019-03-14 2025-07-07 スミトモ・ファーマ・アメリカ・インコーポレイテッド イソクロマニル化合物の塩およびその結晶体、ならびにそれらの製造方法、治療用途および医薬組成物
CN110746269A (zh) * 2019-11-06 2020-02-04 山西中医药大学 一种1,3-丙二醇的合成方法
CN115734785A (zh) 2020-04-14 2023-03-03 桑诺维恩药品公司 (S)-(4,5-二氢-7H-噻吩并[2,3-c]吡喃-7-基)-N-甲基甲胺用于治疗神经和精神方面的病症
CN115677719B (zh) * 2022-10-27 2025-03-07 复旦大学 一种芳基并杂环化合物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162803A (en) * 1998-04-08 2000-12-19 American Home Products Corp. Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression
TW520367B (en) * 1998-04-29 2003-02-11 Wyeth Corp Indolyl derivatives as serotonergic agents
TW528754B (en) * 1998-04-29 2003-04-21 Wyeth Corp Indolyl derivatibes as serotonergic agents
WO2000040581A1 (en) * 1999-01-07 2000-07-13 American Home Products Corporation 3,4-dihydro-2h-benzo[1,4]oxazine derivatives

Also Published As

Publication number Publication date
EP1409476B1 (de) 2004-12-15
EP1409476A1 (de) 2004-04-21
WO2003006455A1 (en) 2003-01-23

Similar Documents

Publication Publication Date Title
SE0001899D0 (sv) New compounds
BR0015188A (pt) Composições farmacêuticas
BRPI0417717A (pt) composto, composição farmacêutica, e, uso de um composto
EE200000320A (et) Uudsed ühendid
SE9704544D0 (sv) Novel compounds
BR0208338A (pt) Derivados de piridina
SE0102438D0 (sv) New compounds
SE0201544D0 (sv) Novel compounds and thier use
DE60236541D1 (de) Inhibitoren von 11-beta-hydroxysteroiddehydrogenase typ 1
EE05183B1 (et) Asabitsklilised hendid, nende valmistamine ja kasutamine ravimitena ning neid sisaldav farmatseutiline kompositsioon
SV1999000049A (es) Nuevas dihidropirimidinas 2 heterociclicamente sustituidas ref. lea 32793-sv
ATE303149T1 (de) Orale pharmazeutische zusammensetzung aus cefpodoxim-proxetil
DE60336225D1 (de) Neue pharmazeutische zusammenstezungen, flibanserin polymorph a enthaltend
ATE284878T1 (de) Pharmazeutische verbindungen mit serotonin rezeptor aktivität
SE9902765D0 (sv) Novel compounds
ATE252377T1 (de) Kontrolliert freisetzende pharmazeutische zusammensetzung mit tilidinmesylat als wirkstoff
MY133112A (en) 3-amino-3-arylpropan-1-ol derivatives, and their preparation and use
MY134026A (en) ?-carboline derivatives and its pharmaceutical use against depression and anxiety
MXPA04001419A (es) Isoxazolopiridinonas y su uso en el tratamiento de enfermedad de parkinson.
BR0012553A (pt) Pastilhas contendo ambroxol
BR0114380A (pt) Derivados-1-aminobutan-3-ol-substituìdos
HRP20080597T3 (en) Cancer combination therapy comprising azd2171 and zd1839
MY139613A (en) Novel piperazinyl-pyrazinone derivatives for the treatment of 5-ht2a receptor-related disorders
ATE338567T1 (de) Pharmazeutische zubereitungen, wirkstoffe enthaltend, die sich für unerlaubte verabreichung anbieten
CY1106964T1 (el) Φαρμακα που περιεχουν ν,ν’-διυποκατεστημενες ενωσεις πιπεραζινης και η χρησιμοποιηση τους

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties