ATE285177T1 - Thiole zur förderung des wachstumsvon hömatopoietischen vorläuferzellen - Google Patents

Thiole zur förderung des wachstumsvon hömatopoietischen vorläuferzellen

Info

Publication number
ATE285177T1
ATE285177T1 AT96906519T AT96906519T ATE285177T1 AT E285177 T1 ATE285177 T1 AT E285177T1 AT 96906519 T AT96906519 T AT 96906519T AT 96906519 T AT96906519 T AT 96906519T AT E285177 T1 ATE285177 T1 AT E285177T1
Authority
AT
Austria
Prior art keywords
growth
cells
progenicial
hometopoietic
thiole
Prior art date
Application number
AT96906519T
Other languages
English (en)
Inventor
Robert L Capizzi
Alan F List
Original Assignee
Medimmune Oncology Inc
Univ Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Oncology Inc, Univ Arizona filed Critical Medimmune Oncology Inc
Application granted granted Critical
Publication of ATE285177T1 publication Critical patent/ATE285177T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96906519T 1995-02-17 1996-02-16 Thiole zur förderung des wachstumsvon hömatopoietischen vorläuferzellen ATE285177T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/390,713 US5846958A (en) 1995-02-17 1995-02-17 Methods of using aminothiols to promote hematopoietic progenitor cell growth
PCT/US1996/002188 WO1996025045A1 (en) 1995-02-17 1996-02-16 Thiols to promote hematopoietic progenitor cell growth

Publications (1)

Publication Number Publication Date
ATE285177T1 true ATE285177T1 (de) 2005-01-15

Family

ID=23543611

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96906519T ATE285177T1 (de) 1995-02-17 1996-02-16 Thiole zur förderung des wachstumsvon hömatopoietischen vorläuferzellen

Country Status (10)

Country Link
US (2) US5846958A (de)
EP (1) EP0809437B1 (de)
JP (1) JP4057648B2 (de)
AT (1) ATE285177T1 (de)
AU (1) AU694847B2 (de)
CA (1) CA2213322C (de)
DE (1) DE69634074T2 (de)
ES (1) ES2235183T3 (de)
PT (1) PT809437E (de)
WO (1) WO1996025045A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6573253B2 (en) 1997-02-12 2003-06-03 Medimmune Oncology Inc. Methods for the administration of amifostine and related compounds
US6051563A (en) * 1997-02-12 2000-04-18 U.S. Bioscience, Inc. Methods for the administration of amifostine and related compounds
US5994409A (en) * 1997-12-09 1999-11-30 U.S. Bioscience, Inc. Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds
US6953777B2 (en) * 1999-03-11 2005-10-11 Genetics Indtitute LLC Use of interleukin-11 to prevent immune-mediated cytotoxicity
US6489312B1 (en) * 1999-06-15 2002-12-03 Medimmune Oncology, Inc. Pharmaceutical formulations comprising aminoalkyl phosphorothioates
US7022315B2 (en) * 2000-04-26 2006-04-04 Oregon Health & Science University Administration of a thiol-based chemoprotectant compound
US7053072B2 (en) 2001-05-11 2006-05-30 Medimmune Oncology, Inc. Methods for the administration of amifostine and related compounds
WO2003049693A2 (en) * 2001-12-06 2003-06-19 Wyeth Method and composition for inducing weight loss
US6982080B2 (en) * 2002-03-15 2006-01-03 Wyeth Hydroxyethyl starch—containing polypeptide compositions
WO2004024125A1 (en) * 2002-09-16 2004-03-25 Wyeth Delayed release formulations for oral administration of a polypeptide therapeutic agent and methods of using same
WO2004039336A2 (en) * 2002-10-31 2004-05-13 Oregon Health & Science University Use of thiol-based compositions in treating chemotherapeutic agent-induced thrombocytopenia
US20070148154A1 (en) * 2004-12-17 2007-06-28 Universite Rene Descartes (Paris V) Use of superoxide dismutase mimetics and reductase gultatione in the form of anticancer drugs
WO2007096901A1 (en) * 2006-02-24 2007-08-30 Natco Pharma Limited Novel dihydrate form of amifostine and process for its preparation
US20130230580A1 (en) * 2010-09-14 2013-09-05 Paul S. Frenette Administration of SNS Neuroprotective Agents to Promote Hematopoietic Regeneration
CN108495625B (zh) 2015-11-17 2021-07-27 柏林顿Hc研究集团有限公司 改善对氨基硫醇及其类似物的保护和递送的方法
GB201706544D0 (en) * 2017-04-25 2017-06-07 Plasticell Ltd Method
EP3656847B1 (de) 2017-07-28 2022-08-17 Nissan Chemical Corporation Additivzusammensetzung für kulturmedium, additivverbindung für kulturmedium und verfahren zur kultivierung von zellen oder gewebe unter verwendung davon
GB201817385D0 (en) * 2018-10-25 2018-12-12 Plasticell Ltd Therapy
CN113348017A (zh) 2019-01-30 2021-09-03 日产化学株式会社 酰肼化合物及激酶抑制剂
GB202303026D0 (en) 2023-03-01 2023-04-12 Plasticell Ltd Therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892824A (en) * 1968-12-16 1975-07-01 Southern Res Inst S-{107 -({107 -aminoalkylamino)alkyl dihydrogen phosphorothioates
US4656034A (en) * 1985-05-20 1987-04-07 Survival Technology, Inc. Absorption enhancing agents
EP0394542A1 (de) * 1989-04-25 1990-10-31 American Cyanamid Company Wiederherstellung der Knochenmarkszellen mit synthetischen CSF-Induktoren
AU6647190A (en) * 1989-10-10 1991-05-16 University Of Rochester Method for producing bone marrow growth cell factors
PT100914A (pt) * 1991-09-30 1993-10-29 Jess G Thoene Uso de compostos capazes de sofrer uma permuta mista com dissulfureto, com uma ligacao dissulfureto, no tratamento de infeccao por hiv
US5824664A (en) * 1993-03-26 1998-10-20 U.S. Bioscience, Inc. Suppression of HIV expression by organic thiophosphate

Also Published As

Publication number Publication date
US5846958A (en) 1998-12-08
PT809437E (pt) 2005-05-31
AU694847B2 (en) 1998-07-30
CA2213322A1 (en) 1996-08-22
JP4057648B2 (ja) 2008-03-05
EP0809437A4 (de) 2001-05-09
DE69634074T2 (de) 2006-01-19
US5906984A (en) 1999-05-25
AU4986996A (en) 1996-09-04
JPH11504000A (ja) 1999-04-06
CA2213322C (en) 2008-05-13
WO1996025045A1 (en) 1996-08-22
EP0809437A1 (de) 1997-12-03
ES2235183T3 (es) 2005-07-01
MX9706255A (es) 1998-08-30
DE69634074D1 (de) 2005-01-27
EP0809437B1 (de) 2004-12-22

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