|
US6368801B1
(en)
*
|
2000-04-12 |
2002-04-09 |
Molecular Staging, Inc. |
Detection and amplification of RNA using target-mediated ligation of DNA by RNA ligase
|
|
JP3596868B2
(ja)
*
|
2000-11-24 |
2004-12-02 |
キヤノン株式会社 |
末端標識プローブアレイのプローブの量の評価方法、及び、該標識プローブアレイを用いた標的物質量の評価方法
|
|
JP2004537263A
(ja)
*
|
2000-12-14 |
2004-12-16 |
ジェン−プローブ・インコーポレーテッド |
ポリヌクレオチドの会合速度を増強するための方法およびキット
|
|
ATE346950T1
(de)
*
|
2001-03-09 |
2006-12-15 |
Boston Probes Inc |
Kombinationsoligomere betreffende verfahren, kits und zusammensetzungen
|
|
CA2441021C
(en)
*
|
2001-03-15 |
2013-09-17 |
Exact Sciences Corporation |
Method for alteration detection
|
|
US7195872B2
(en)
*
|
2001-11-09 |
2007-03-27 |
3D Biosurfaces, Inc. |
High surface area substrates for microarrays and methods to make same
|
|
US6946245B2
(en)
|
2001-12-04 |
2005-09-20 |
Quest Diagnostics Investments Incorporated |
Oligonucleotides and methods for detecting hepatitis C viral nucleic acids
|
|
US6686162B2
(en)
|
2001-12-04 |
2004-02-03 |
Quest Diagnostics Investments, Incorporated |
Oligonucleotides and methods for detecting Borrelia burgdorferi
|
|
AU2003212878A1
(en)
*
|
2002-01-30 |
2003-09-02 |
Epigenomics Ag |
Identification of cell differentiation states based on methylation patterns
|
|
EP2112229A3
(de)
|
2002-11-25 |
2009-12-02 |
Sequenom, Inc. |
Verfahren zum Identifizieren des Brustkrebsrisikos und zugehörige Behandlungen
|
|
US9487823B2
(en)
|
2002-12-20 |
2016-11-08 |
Qiagen Gmbh |
Nucleic acid amplification
|
|
CN1791682B
(zh)
*
|
2003-02-26 |
2013-05-22 |
凯利达基因组股份有限公司 |
通过杂交进行的随机阵列dna分析
|
|
US20040259128A1
(en)
*
|
2003-03-24 |
2004-12-23 |
Glenn Kawasaki |
Methods and compositions for detecting the presence of target nucleic acids in a sample
|
|
US20040203005A1
(en)
*
|
2003-04-14 |
2004-10-14 |
White Wanda L. B. |
Dual hybridization of complex nucleic acid samples for sequencing and single-nucleotide polymorphism identification
|
|
EP1668158B1
(de)
*
|
2003-08-11 |
2010-10-20 |
Georgia State University Research Foundation, Inc. |
Rna-nachweis und quantifizierung
|
|
US20050153300A1
(en)
*
|
2004-01-09 |
2005-07-14 |
Quest Diagnostics Incorporated |
Methods and compositions for the detection of mucolipidosis IV mutations
|
|
EP1721011A1
(de)
|
2004-03-01 |
2006-11-15 |
Applera Corporation |
Verfahren, zusammensetzungen und kits zur verwendung bei der polynukleotidamplifikation
|
|
US7575863B2
(en)
|
2004-05-28 |
2009-08-18 |
Applied Biosystems, Llc |
Methods, compositions, and kits comprising linker probes for quantifying polynucleotides
|
|
US20060057595A1
(en)
*
|
2004-09-16 |
2006-03-16 |
Applera Corporation |
Compositions, methods, and kits for identifying and quantitating small RNA molecules
|
|
WO2006052842A2
(en)
|
2004-11-09 |
2006-05-18 |
The Trustees Of The University Of Pennsylvania |
Methods for diagnosis of myelodysplastic syndromes (mds)
|
|
US7700287B2
(en)
*
|
2005-01-28 |
2010-04-20 |
Life Technologies Corporation |
Compositions and methods for terminating a sequencing reaction at a specific location in a target DNA template
|
|
DE602005018840D1
(de)
*
|
2005-04-14 |
2010-02-25 |
Applied Biosystems Llc |
3'-modifizierte oligonukleotide mit pseudoisocytosin-nukleobasenderivaten sowie deren anwendungen als primer oder sonden
|
|
DK1907571T3
(en)
|
2005-06-15 |
2017-08-21 |
Complete Genomics Inc |
NUCLEIC ACID ANALYSIS USING INCIDENTAL MIXTURES OF NON-OVERLAPPING FRAGMENTS
|
|
US7892737B2
(en)
*
|
2005-06-30 |
2011-02-22 |
Life Technologies Corporation |
Compositions, kits and methods pertaining to stability modulation of PNA oligomer/nucleic acid complexes
|
|
EP1762627A1
(de)
|
2005-09-09 |
2007-03-14 |
Qiagen GmbH |
Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
|
|
US7960104B2
(en)
*
|
2005-10-07 |
2011-06-14 |
Callida Genomics, Inc. |
Self-assembled single molecule arrays and uses thereof
|
|
CN101432439B
(zh)
|
2006-02-24 |
2013-07-24 |
考利达基因组股份有限公司 |
Dna阵列上的高通量基因组测序
|
|
SG170028A1
(en)
|
2006-02-24 |
2011-04-29 |
Callida Genomics Inc |
High throughput genome sequencing on dna arrays
|
|
US7951572B2
(en)
*
|
2006-02-27 |
2011-05-31 |
Korea Advanced Institute Of Science And Technology |
Construction of gold nanoparticle-based peptide chip, and assaying enzyme activity and inhibitor effect using secondary ion mass spectrometric analysis thereof
|
|
US8895711B2
(en)
*
|
2006-04-18 |
2014-11-25 |
The Trustees Of The University Of Pennsylvania |
Mutated ACVR1 for diagnosis and treatment of Fibrodyplasia Ossificans Progressiva (FOP)
|
|
US8859752B2
(en)
|
2006-04-18 |
2014-10-14 |
The Trustees Of The University Of Pennsylvania |
SIRNA-based therapy of Fibrodyplasia Ossificans Progressiva (FOP)
|
|
WO2007133703A2
(en)
*
|
2006-05-10 |
2007-11-22 |
Dxterity Diagnostics |
Detection of nucleic acid targets using chemically reactive oligonucleotide probes
|
|
EP3260556B1
(de)
|
2006-05-31 |
2019-07-31 |
Sequenom, Inc. |
Verfahren zur nukleinsäureextraktion aus einer probe
|
|
US8153369B2
(en)
|
2006-06-05 |
2012-04-10 |
Cancer Care Ontario |
Assessment of risk for colorectal cancer
|
|
EP2029726A4
(de)
*
|
2006-06-09 |
2010-07-28 |
Univ Miami |
Beurteilung der zellenzusammensetzung und fraktionelle durchführbarkeit und verwendungen davon
|
|
WO2008070352A2
(en)
|
2006-10-27 |
2008-06-12 |
Complete Genomics, Inc. |
Efficient arrays of amplified polynucleotides
|
|
US20090075343A1
(en)
*
|
2006-11-09 |
2009-03-19 |
Complete Genomics, Inc. |
Selection of dna adaptor orientation by nicking
|
|
US20090105961A1
(en)
*
|
2006-11-09 |
2009-04-23 |
Complete Genomics, Inc. |
Methods of nucleic acid identification in large-scale sequencing
|
|
US20080131880A1
(en)
*
|
2006-11-22 |
2008-06-05 |
Bortolin Laura T |
PNA-DNA oligomers and methods of use thereof
|
|
US7902345B2
(en)
|
2006-12-05 |
2011-03-08 |
Sequenom, Inc. |
Detection and quantification of biomolecules using mass spectrometry
|
|
EP2118298B1
(de)
|
2007-02-08 |
2013-01-09 |
Sequenom, Inc. |
Tests auf nukleinsäurebasis für rhd-typisierung
|
|
US20080194416A1
(en)
*
|
2007-02-08 |
2008-08-14 |
Sigma Aldrich |
Detection of mature small rna molecules
|
|
AU2008222563A1
(en)
|
2007-03-05 |
2008-09-12 |
Cancer Care Ontario |
Assessment of risk for colorectal cancer
|
|
EP2140031A4
(de)
|
2007-03-26 |
2011-04-20 |
Sequenom Inc |
Restriktionsendonukleaseverstärkte polymorphe sequenzerfassung
|
|
US8008010B1
(en)
|
2007-06-27 |
2011-08-30 |
Applied Biosystems, Llc |
Chimeric oligonucleotides for ligation-enhanced nucleic acid detection, methods and compositions therefor
|
|
WO2009032781A2
(en)
|
2007-08-29 |
2009-03-12 |
Sequenom, Inc. |
Methods and compositions for universal size-specific polymerase chain reaction
|
|
US20090061424A1
(en)
*
|
2007-08-30 |
2009-03-05 |
Sigma-Aldrich Company |
Universal ligation array for analyzing gene expression or genomic variations
|
|
WO2009052214A2
(en)
|
2007-10-15 |
2009-04-23 |
Complete Genomics, Inc. |
Sequence analysis using decorated nucleic acids
|
|
US8415099B2
(en)
|
2007-11-05 |
2013-04-09 |
Complete Genomics, Inc. |
Efficient base determination in sequencing reactions
|
|
US7897344B2
(en)
|
2007-11-06 |
2011-03-01 |
Complete Genomics, Inc. |
Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs
|
|
US20090263872A1
(en)
*
|
2008-01-23 |
2009-10-22 |
Complete Genomics Inc. |
Methods and compositions for preventing bias in amplification and sequencing reactions
|
|
US8518640B2
(en)
|
2007-10-29 |
2013-08-27 |
Complete Genomics, Inc. |
Nucleic acid sequencing and process
|
|
WO2009061840A1
(en)
|
2007-11-05 |
2009-05-14 |
Complete Genomics, Inc. |
Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation
|
|
WO2009073629A2
(en)
|
2007-11-29 |
2009-06-11 |
Complete Genomics, Inc. |
Efficient shotgun sequencing methods
|
|
US8592150B2
(en)
|
2007-12-05 |
2013-11-26 |
Complete Genomics, Inc. |
Methods and compositions for long fragment read sequencing
|
|
KR20090081260A
(ko)
*
|
2008-01-23 |
2009-07-28 |
삼성전자주식회사 |
마이크로 어레이 혼성화 검출 방법
|
|
WO2009097368A2
(en)
|
2008-01-28 |
2009-08-06 |
Complete Genomics, Inc. |
Methods and compositions for efficient base calling in sequencing reactions
|
|
WO2009120808A2
(en)
|
2008-03-26 |
2009-10-01 |
Sequenom, Inc. |
Restriction endonuclease enhanced polymorphic sequence detection
|
|
WO2009132028A1
(en)
*
|
2008-04-21 |
2009-10-29 |
Complete Genomics, Inc. |
Array structures for nucleic acid detection
|
|
JP5438922B2
(ja)
*
|
2008-06-25 |
2014-03-12 |
日東電工株式会社 |
核酸の製造方法
|
|
US8476013B2
(en)
|
2008-09-16 |
2013-07-02 |
Sequenom, Inc. |
Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
|
US8962247B2
(en)
|
2008-09-16 |
2015-02-24 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
|
|
IL313131A
(en)
|
2009-02-11 |
2024-07-01 |
Caris Mpi Inc |
Molecular characterization of tumors
|
|
WO2010114599A1
(en)
|
2009-04-01 |
2010-10-07 |
Dx Terity Diagnostics Inc. |
Chemical ligation dependent probe amplification (clpa)
|
|
US8771948B2
(en)
|
2009-04-03 |
2014-07-08 |
Sequenom, Inc. |
Nucleic acid preparation compositions and methods
|
|
US9524369B2
(en)
|
2009-06-15 |
2016-12-20 |
Complete Genomics, Inc. |
Processing and analysis of complex nucleic acid sequence data
|
|
US8728725B2
(en)
*
|
2009-07-06 |
2014-05-20 |
Trilink Biotechnologies |
Chemically modified ligase cofactors, donors and acceptors
|
|
US9631227B2
(en)
|
2009-07-06 |
2017-04-25 |
Trilink Biotechnologies, Inc. |
Chemically modified ligase cofactors, donors and acceptors
|
|
WO2011012280A1
(en)
*
|
2009-07-30 |
2011-02-03 |
Roche Diagnostics Gmbh |
A set of oligonucleotide probes as well as methods and uses related thereto
|
|
US12410463B2
(en)
|
2009-09-18 |
2025-09-09 |
The Trustees Of The University Of Pennsylvania |
Molecular beacons
|
|
CA2779223A1
(en)
|
2009-10-27 |
2011-05-12 |
Caris Mpi, Inc. |
Molecular profiling for personalized medicine
|
|
DK2516680T3
(en)
|
2009-12-22 |
2016-05-02 |
Sequenom Inc |
Method and kits to identify aneuploidy
|
|
US9404160B2
(en)
|
2009-12-22 |
2016-08-02 |
Becton, Dickinson And Company |
Methods for the detection of microorganisms
|
|
US10066257B2
(en)
|
2010-03-29 |
2018-09-04 |
Dxterity Diagnostics Incorporated |
Methods and compositions for detecting target nucleic acids
|
|
US9777332B2
(en)
|
2011-03-31 |
2017-10-03 |
St. Jude Children's Research Hospital |
Methods and compositions for identifying minimal residual disease in acute lymphoblastic leukemia
|
|
WO2013119845A1
(en)
|
2012-02-07 |
2013-08-15 |
Vibrant Holdings, Llc |
Substrates, peptide arrays, and methods
|
|
EP4155401A1
(de)
|
2012-03-02 |
2023-03-29 |
Sequenom, Inc. |
Verfahren und prozesse zur nichtinvasiven beurteilung genetischer variationen
|
|
US9920361B2
(en)
|
2012-05-21 |
2018-03-20 |
Sequenom, Inc. |
Methods and compositions for analyzing nucleic acid
|
|
KR101974577B1
(ko)
*
|
2012-05-21 |
2019-05-02 |
삼성전자주식회사 |
나노입자 제작용 주형 및 이를 이용한 나노입자의 제조 방법
|
|
US10504613B2
(en)
|
2012-12-20 |
2019-12-10 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
US20140093873A1
(en)
|
2012-07-13 |
2014-04-03 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
|
US10006909B2
(en)
|
2012-09-28 |
2018-06-26 |
Vibrant Holdings, Llc |
Methods, systems, and arrays for biomolecular analysis
|
|
EP2929050A1
(de)
|
2012-12-10 |
2015-10-14 |
AdvanDx, Inc. |
Verwendung von sonden zur massenspektrometrischen identifizierung von mikroorganismen oder zellen und relevanten erkrankungen von interesse
|
|
US9896728B2
(en)
|
2013-01-29 |
2018-02-20 |
Arcticrx Ltd. |
Method for determining a therapeutic approach for the treatment of age-related macular degeneration (AMD)
|
|
US9289502B2
(en)
|
2013-03-08 |
2016-03-22 |
Emerald Therapeutics, Inc. |
Preparation of oligo conjugates
|
|
EP3597774A1
(de)
|
2013-03-13 |
2020-01-22 |
Sequenom, Inc. |
Primer zur analyse der dna-methylierung
|
|
WO2015138774A1
(en)
|
2014-03-13 |
2015-09-17 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
WO2015191777A2
(en)
|
2014-06-10 |
2015-12-17 |
Dxterity Diagnostics Incorporated |
Devices and methods for collecting and stabilizing biological samples
|
|
GB201612011D0
(en)
|
2016-07-11 |
2016-08-24 |
Glaxosmithkline Ip Dev Ltd |
Novel processes for the production of oligonucleotides
|
|
EP3299472A1
(de)
*
|
2016-09-27 |
2018-03-28 |
Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts |
Verfahren zur markierung von oligonukleotidsonden
|
|
EP3736324A1
(de)
|
2016-09-30 |
2020-11-11 |
The Governing Council Of The University Of Toronto |
System zur identifizierung und zum targeting einzelner zellen in einer heterogenen population zur selektiven extraktion von zellgehalt
|
|
WO2018218250A2
(en)
|
2017-05-26 |
2018-11-29 |
Vibrant Holdings, Llc |
Photoactive compounds and methods for biomolecule detection and sequencing
|
|
GB201721307D0
(en)
|
2017-12-19 |
2018-01-31 |
Glaxosmithkline Ip Dev Ltd |
Novel processes for the production of oligonucleotides
|
|
WO2019202536A1
(en)
|
2018-04-18 |
2019-10-24 |
St. Jude Children's Research Hospital |
Genotyping assays to identify mutations in xaf1
|
|
EP3790985B1
(de)
|
2018-05-09 |
2026-04-15 |
Vibrant Holdings, LLC |
Verfahren zur synthese eines polynukleotidarrays unter verwendung von fotootaktivierten mitteln
|
|
KR20210111254A
(ko)
|
2018-11-30 |
2021-09-10 |
캐리스 엠피아이, 아이엔씨. |
차세대 분자 프로파일링
|
|
US20220280544A1
(en)
*
|
2019-07-24 |
2022-09-08 |
Tohoku University |
Chimeric molecule, pharmaceutical composition, method for cleaving target nucleic acid, and kit for target nucleic acid cleavage or diagnosis
|
|
IL293489A
(en)
|
2019-12-02 |
2022-08-01 |
Caris Mpi Inc |
predictor of pan-cancer platinum response
|
|
WO2023069429A1
(en)
*
|
2021-10-19 |
2023-04-27 |
Oncogenuity, Inc. |
Peptide nucleic acid compositions and methods of use for gene editing
|