ATE285590T1 - Methode und vorrichtung zur aufnahme dreidimensionaler abbildungen von schwebend gehaltenen mikroobjekten unter verwendung hochauflösender mikroskopie - Google Patents

Methode und vorrichtung zur aufnahme dreidimensionaler abbildungen von schwebend gehaltenen mikroobjekten unter verwendung hochauflösender mikroskopie

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Publication number
ATE285590T1
ATE285590T1 AT02292658T AT02292658T ATE285590T1 AT E285590 T1 ATE285590 T1 AT E285590T1 AT 02292658 T AT02292658 T AT 02292658T AT 02292658 T AT02292658 T AT 02292658T AT E285590 T1 ATE285590 T1 AT E285590T1
Authority
AT
Austria
Prior art keywords
receptacle
data sets
microobjects
floated
capturing
Prior art date
Application number
AT02292658T
Other languages
English (en)
Inventor
Spencer Shorte
Torsten Mueller
Thomas Schnelle
Original Assignee
Evotec Technologies Gmbh
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evotec Technologies Gmbh, Pasteur Institut filed Critical Evotec Technologies Gmbh
Application granted granted Critical
Publication of ATE285590T1 publication Critical patent/ATE285590T1/de

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Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/18Arrangements with more than one light path, e.g. for comparing two specimens
    • G02B21/20Binocular arrangements
    • G02B21/22Stereoscopic arrangements
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365Control or image processing arrangements for digital or video microscopes
    • G02B21/367Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N2015/144Imaging characterised by its optical setup
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N2015/144Imaging characterised by its optical setup
    • G01N2015/1445Three-dimensional imaging, imaging in different image planes, e.g. under different angles or at different depths, e.g. by a relative motion of sample and detector, for instance by tomography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N2015/1452Adjustment of focus; Alignment

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT02292658T 2002-10-25 2002-10-25 Methode und vorrichtung zur aufnahme dreidimensionaler abbildungen von schwebend gehaltenen mikroobjekten unter verwendung hochauflösender mikroskopie ATE285590T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02292658A EP1413911B1 (de) 2002-10-25 2002-10-25 Methode und Vorrichtung zur Aufnahme dreidimensionaler Abbildungen von schwebend gehaltenen Mikroobjekten unter Verwendung hochauflösender Mikroskopie

Publications (1)

Publication Number Publication Date
ATE285590T1 true ATE285590T1 (de) 2005-01-15

Family

ID=32050117

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02292658T ATE285590T1 (de) 2002-10-25 2002-10-25 Methode und vorrichtung zur aufnahme dreidimensionaler abbildungen von schwebend gehaltenen mikroobjekten unter verwendung hochauflösender mikroskopie

Country Status (6)

Country Link
US (1) US7738695B2 (de)
EP (1) EP1413911B1 (de)
AT (1) ATE285590T1 (de)
AU (1) AU2003298099A1 (de)
DE (1) DE60202374T2 (de)
WO (1) WO2004038484A2 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050036674A1 (en) * 2003-08-13 2005-02-17 Bar Ilan University Method and system for determining shape of an object from a planar top view thereof
DE102004023466B4 (de) * 2004-05-12 2008-11-13 Evotec Technologies Gmbh Verfahren und Vorrichtung zur Sammlung von suspendierten Partikeln
US9041938B2 (en) 2006-05-02 2015-05-26 California Institute Of Technology Surface wave assisted structures and systems
US8822894B2 (en) 2011-01-07 2014-09-02 California Institute Of Technology Light-field pixel for detecting a wavefront based on a first intensity normalized by a second intensity
US7768654B2 (en) 2006-05-02 2010-08-03 California Institute Of Technology On-chip phase microscope/beam profiler based on differential interference contrast and/or surface plasmon assisted interference
US8055034B2 (en) * 2006-09-13 2011-11-08 Fluidigm Corporation Methods and systems for image processing of microfluidic devices
US8050516B2 (en) * 2006-09-13 2011-11-01 Fluidigm Corporation Methods and systems for determining a baseline during image processing
DE102006052925A1 (de) * 2006-11-09 2008-05-15 Evotec Technologies Gmbh Feldkäfig und zugehöriges Betriebsverfahren
US8224066B2 (en) * 2007-05-29 2012-07-17 Gerd Haeusler Method and microscopy device for the deflectometric detection of local gradients and the three-dimensional shape of an object
WO2009029843A1 (en) * 2007-08-31 2009-03-05 The General Hospital Corporation System and method for self-interference fluoresence microscopy, and computer-accessible medium associated therewith
DE102007045897A1 (de) * 2007-09-26 2009-04-09 Carl Zeiss Microimaging Gmbh Verfahren zur mikroskopischen dreidimensionalen Abbildung einer Probe
FR2923054B1 (fr) * 2007-10-24 2009-12-11 Centre Nat Rech Scient Procede et dispositif de reconstruction du volume d'un objet a partir d'une sequence d'images de coupes dudit objet
JP2009115891A (ja) * 2007-11-02 2009-05-28 Univ Of Tokyo 走査型顕微鏡および標本画像取得方法
WO2009111573A2 (en) 2008-03-04 2009-09-11 California Institute Of Technology Optofluidic microscope device with photosensor array
US8325349B2 (en) 2008-03-04 2012-12-04 California Institute Of Technology Focal plane adjustment by back propagation in optofluidic microscope devices
WO2009111577A1 (en) * 2008-03-04 2009-09-11 California Institute Of Technology Methods of using optofluidic microscope devices
FR2929417B1 (fr) 2008-03-27 2010-05-21 Univ Paris 13 Procede de determination d'une representation tridimensionnelle d'un objet a partir de points, programme d'ordinateur et systeme d'imagerie correspondant
FR2929416B1 (fr) * 2008-03-27 2010-11-05 Univ Paris 13 Procede de determination d'une representation tridimensionnelle d'un objet a partir d'une sequence d'images en coupe, produit programme d'ordinateur, procede d 'analyse d'un objet et systeme d'imagerie correspondants
US8155409B2 (en) * 2008-04-17 2012-04-10 Ruprecht-Karls-Universitat Wave field microscope with sub-wavelength resolution and methods for processing microscopic images to detect objects with sub-wavelength dimensions
US8039776B2 (en) 2008-05-05 2011-10-18 California Institute Of Technology Quantitative differential interference contrast (DIC) microscopy and photography based on wavefront sensors
US8693742B2 (en) * 2008-12-17 2014-04-08 The Regents Of The University Of Colorado Three-dimensional single-molecule fluorescence imaging beyond the diffraction limit using a double-helix point spread function
CN102292662A (zh) 2009-01-21 2011-12-21 加州理工学院 用于计算深度切片的定量微分干涉差(dic)设备
US8416400B2 (en) * 2009-06-03 2013-04-09 California Institute Of Technology Wavefront imaging sensor
US8633432B2 (en) * 2009-09-21 2014-01-21 California Institute Of Technology Reflective focusing and transmissive projection device
WO2011047053A2 (en) * 2009-10-13 2011-04-21 California Institute Of Technology Holographically illuminated imaging devices
WO2011106324A2 (en) 2010-02-23 2011-09-01 California Institute Of Technology Nondiffracting beam detection devices for three-dimensional imaging
CN102792151B (zh) 2010-03-23 2015-11-25 加州理工学院 用于2d和3d成像的超分辨率光流体显微镜
US8620065B2 (en) 2010-04-09 2013-12-31 The Regents Of The University Of Colorado Methods and systems for three dimensional optical imaging, sensing, particle localization and manipulation
WO2012033957A2 (en) 2010-09-09 2012-03-15 California Institute Of Technology Delayed emission detection devices and methods
US9693034B2 (en) 2011-12-13 2017-06-27 The Board Of Trustees Of The Leland Stanford Junior University Apparatus and method for localizing objects for distance and/or in three dimensions using a spiral point spread function
US10955331B2 (en) 2012-06-22 2021-03-23 The Regents Of The University Of Colorado, A Body Corporate Imaging or measurement methods and systems
US9091628B2 (en) 2012-12-21 2015-07-28 L-3 Communications Security And Detection Systems, Inc. 3D mapping with two orthogonal imaging views
WO2014144820A1 (en) * 2013-03-15 2014-09-18 The Regents Of The University Of Colorado 3-d localization and imaging of dense arrays of particles
US10036735B2 (en) 2013-08-26 2018-07-31 The Regents Of The University Of Colorado, A Body Corporate Imaging through scattering media with high signal to noise ratio and resolution
US9810893B2 (en) 2014-03-27 2017-11-07 The Board Of Trustees Of The Leland Stanford Junior University Phase mask imaging with characterization of rotational mobility
EP3215806A4 (de) 2014-11-05 2018-06-06 The Regents Of The University Of Colorado 3d-bildgebung, entfernungsmessung und/oder verfolgung mit aktiver beleuchtung und konstruktion einer punktausbreitungsfunktion
US10416065B2 (en) * 2014-12-16 2019-09-17 Celldynamics I.S.R.L. Device for real time analysis of particles suspended in a fluid and method for the analysis of said particles
WO2016157346A1 (ja) * 2015-03-27 2016-10-06 株式会社ニコン 顕微鏡装置、観察方法、及び制御プログラム
US10341640B2 (en) 2015-04-10 2019-07-02 The Board Of Trustees Of The Leland Stanford Junior University Multi-wavelength phase mask
US11327004B2 (en) 2016-03-02 2022-05-10 Arizona Board Of Regents On Behalf Of Arizona State University Live-cell computed tomography
JP6681068B2 (ja) * 2016-06-14 2020-04-15 国立研究開発法人理化学研究所 データ復元装置、顕微鏡システム、およびデータ復元方法
US11315292B2 (en) 2017-03-02 2022-04-26 Arizona Board Of Regents On Behalf Of Arizona State University Live-cell computed tomography
CN112005278A (zh) * 2018-04-27 2020-11-27 惠普发展公司,有限责任合伙企业 非旋转非均匀电场对象旋转
US11481964B2 (en) 2018-04-27 2022-10-25 Hewlett-Packard Development Company, L.P. Three dimensional volume imaging
US11543356B2 (en) * 2018-10-29 2023-01-03 Hewlett-Packard Development Company, L.P. Rotation and flat-form imaging for microscopic objects
CN114166699A (zh) * 2021-11-12 2022-03-11 清华大学深圳国际研究生院 一种悬浮颗粒体积的光学测量装置和方法
DE102022117214A1 (de) 2022-07-11 2024-01-11 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Ptychographisches Bildgebungsverfahren und -system
US12467939B2 (en) 2022-07-15 2025-11-11 The George Washington University Optical probe for measuring wall-shear stress
CN115091107B (zh) * 2022-08-24 2023-04-25 中国工程物理研究院激光聚变研究中心 一种用于激光加工的高精度装夹装置及装夹方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3129471B2 (ja) * 1991-06-01 2001-01-29 科学技術振興事業団 マルチビーム微粒子操作方法
ATE171393T1 (de) * 1994-02-24 1998-10-15 Fraunhofer Ges Forschung Formen von mikropartikeln in elektrischen feldkaefigen
DE59610763D1 (de) * 1995-02-08 2003-11-13 Dietmar Schwertner Verfahren und anordnung zur hochauflösenden stereomikroskopie mit erweiterter raumtiefe
US5620857A (en) * 1995-06-07 1997-04-15 United States Of America, As Represented By The Secretary Of Commerce Optical trap for detection and quantitation of subzeptomolar quantities of analytes
DE19653661C1 (de) * 1996-12-20 1998-05-20 Guenter Prof Dr Fuhr Verfahren und Vorrichtung zur Mikropartikelpositionierung in Feldkäfigen
DE19757785B4 (de) * 1997-12-28 2005-09-01 Günter Prof. Dr. Fuhr Verfahren zur Bestimmung optisch induzierter Kräfte
DE19859461A1 (de) * 1998-12-22 2000-06-29 Evotec Biosystems Ag Verfahren und Vorrichtung zur konvektiven Bewegung von Flüssigkeiten in Mikrosystemen
DE19859460C2 (de) * 1998-12-22 2001-02-22 Guenter Fuhr Verfahren und Vorrichtung zur elektro-optischen Einzelpartikelspektroskopie
DE19903001A1 (de) * 1999-01-26 2000-08-24 Evotec Biosystems Ag Verfahren und Vorrichtung zur Detektion mikroskopisch kleiner Objekte
CN1181337C (zh) * 2000-08-08 2004-12-22 清华大学 微流体系统中实体分子的操纵方法及相关试剂盒
US6806899B1 (en) * 1999-07-17 2004-10-19 David F. Schaack Focusing systems for perspective dimensional measurements and optical metrology
JP2001108619A (ja) * 1999-10-12 2001-04-20 Minolta Co Ltd 分析装置、試料操作針および試料取り出し方法
US6891671B1 (en) * 2000-04-18 2005-05-10 Gary Greenberg Apparatus and methods for creating real-time 3-D images and constructing 3-D models of an object imaged in an optical system
US7065242B2 (en) * 2000-03-28 2006-06-20 Viewpoint Corporation System and method of three-dimensional image capture and modeling
EP1205540A1 (de) * 2000-11-10 2002-05-15 Evotec OAI AG Verfahren zur Vitalitätsmessung an Zellen
US6678413B1 (en) * 2000-11-24 2004-01-13 Yiqing Liang System and method for object identification and behavior characterization using video analysis
US7312085B2 (en) * 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
DE10352416B4 (de) * 2003-11-10 2005-10-20 Evotec Technologies Gmbh Verfahren und Vorrichtungen zur Untersuchung eines deformierbaren Objekts
JP4276929B2 (ja) * 2003-11-18 2009-06-10 株式会社日立ハイテクノロジーズ 荷電粒子線色収差補正装置および該収差補正装置を搭載した荷電粒子線装置

Also Published As

Publication number Publication date
EP1413911A1 (de) 2004-04-28
WO2004038484A3 (en) 2004-05-27
AU2003298099A1 (en) 2004-05-13
US7738695B2 (en) 2010-06-15
WO2004038484A2 (en) 2004-05-06
DE60202374D1 (de) 2005-01-27
EP1413911B1 (de) 2004-12-22
AU2003298099A8 (en) 2004-05-13
US20060126921A1 (en) 2006-06-15
DE60202374T2 (de) 2005-12-08

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