ATE285778T1 - Topische verabreichung von bestimmten azapriranen zur vorbeugung oder behandlung von hautzuständen, die mit hautzellhyperproliferation und/oder immunologisch vermittelten krankheiten verbunden sind - Google Patents
Topische verabreichung von bestimmten azapriranen zur vorbeugung oder behandlung von hautzuständen, die mit hautzellhyperproliferation und/oder immunologisch vermittelten krankheiten verbunden sindInfo
- Publication number
- ATE285778T1 ATE285778T1 AT97930236T AT97930236T ATE285778T1 AT E285778 T1 ATE285778 T1 AT E285778T1 AT 97930236 T AT97930236 T AT 97930236T AT 97930236 T AT97930236 T AT 97930236T AT E285778 T1 ATE285778 T1 AT E285778T1
- Authority
- AT
- Austria
- Prior art keywords
- prevention
- treatment
- conditions associated
- skin
- azapriranes
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 210000003491 skin Anatomy 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 210000004927 skin cell Anatomy 0.000 title 1
- 238000011200 topical administration Methods 0.000 title 1
- PWMYMKOUNYTVQN-UHFFFAOYSA-N 3-(8,8-diethyl-2-aza-8-germaspiro[4.5]decan-2-yl)-n,n-dimethylpropan-1-amine Chemical compound C1C[Ge](CC)(CC)CCC11CN(CCCN(C)C)CC1 PWMYMKOUNYTVQN-UHFFFAOYSA-N 0.000 abstract 1
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 206010012442 Dermatitis contact Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 206010039793 Seborrhoeic dermatitis Diseases 0.000 abstract 1
- SERHTTSLBVGRBY-UHFFFAOYSA-N atiprimod Chemical compound C1CC(CCC)(CCC)CCC11CN(CCCN(CC)CC)CC1 SERHTTSLBVGRBY-UHFFFAOYSA-N 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 208000010247 contact dermatitis Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 210000002510 keratinocyte Anatomy 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000017983 photosensitivity disease Diseases 0.000 abstract 1
- 208000008742 seborrheic dermatitis Diseases 0.000 abstract 1
- 229950006315 spirogermanium Drugs 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 239000012049 topical pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/672,728 US5843936A (en) | 1996-06-28 | 1996-06-28 | Topical administration of azaspiranes to prevent or treat skin conditions associated with hyperproliferation of keratinocytes |
| PCT/US1997/011220 WO1998000145A1 (en) | 1996-06-28 | 1997-06-26 | Topical administration of certain azaspiranes to prevent or treat skin conditions associated with hyperproliferation of skin cells and/or immunologically mediated disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE285778T1 true ATE285778T1 (de) | 2005-01-15 |
Family
ID=24699756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97930236T ATE285778T1 (de) | 1996-06-28 | 1997-06-26 | Topische verabreichung von bestimmten azapriranen zur vorbeugung oder behandlung von hautzuständen, die mit hautzellhyperproliferation und/oder immunologisch vermittelten krankheiten verbunden sind |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5843936A (de) |
| EP (1) | EP0909173B1 (de) |
| JP (1) | JP2000514798A (de) |
| AT (1) | ATE285778T1 (de) |
| AU (1) | AU734702B2 (de) |
| CA (1) | CA2257875C (de) |
| DE (1) | DE69732108T2 (de) |
| ES (1) | ES2234021T3 (de) |
| WO (1) | WO1998000145A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100540630B1 (ko) * | 2002-12-12 | 2006-01-11 | 정장수 | 요철형의 절삭날이 형성된 결합형 절삭구로 구성된 드릴공구 |
| US7887842B2 (en) | 2003-02-07 | 2011-02-15 | Teikoku Pharma Usa, Inc. | Methods of administering a dermatological agent to a subject |
| KR101218854B1 (ko) | 2005-11-01 | 2013-01-09 | 사이더로믹스, 엘엘씨 | 갈륨 화합물을 이용한 구강 및 표면 미생물의 성장 제어 |
| CN101489519B (zh) * | 2006-07-14 | 2013-05-08 | 宝洁公司 | 能够同时递送强化护理和总体护理的护理制品 |
| CA2682745C (en) * | 2007-04-02 | 2014-12-23 | Sideromics, Llc | Methods for preventing or treating infectious diseases caused by extracellular microorganisms, including antimicrobial-resistant strains thereof, using gallium compounds |
| CA2935511C (en) | 2014-01-07 | 2023-04-04 | Babita Agrawal | Immunomodulatory compositions comprising heat-killed caulobacter crescentus and methods of use thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE788490A (fr) * | 1971-09-08 | 1973-01-02 | Geschickter Fund Med Res | Azaspiranes substitues par du silicium ou du germanium, leur preparation et compositions pharmaceutiques les contenant |
| US4291030A (en) * | 1980-07-25 | 1981-09-22 | Unimed, Inc. | Method of lowering blood cholesterol |
| US4468393A (en) * | 1982-12-06 | 1984-08-28 | Unimed, Inc. | Treatment of arthritis |
| US4686104A (en) * | 1985-04-30 | 1987-08-11 | Sloan-Kettering Institute For Cancer Research | Methods of treating bone disorders |
| US4654333A (en) * | 1986-02-18 | 1987-03-31 | Unimed, Inc. | Treatment of multiple sclerosis |
| US4963557A (en) * | 1987-09-28 | 1990-10-16 | Smithkline Beecham Corporation | Immunomodulatory azaspiranes |
| US5064835A (en) * | 1990-03-01 | 1991-11-12 | Merck & Co., Inc. | Hydroxymacrolide derivatives having immunosuppressive activity |
| AU658577B2 (en) * | 1990-08-10 | 1995-04-27 | Smithkline Beecham Corporation | Immunosuppressive compositions |
| US5246706A (en) * | 1991-07-19 | 1993-09-21 | Cygnus Therapeutic Systems | Device for administering bimakalim transdermally |
| GB9217116D0 (en) * | 1992-08-13 | 1992-09-23 | Smithkline Beecham Corp | Methods |
-
1996
- 1996-06-28 US US08/672,728 patent/US5843936A/en not_active Expired - Fee Related
-
1997
- 1997-06-26 DE DE69732108T patent/DE69732108T2/de not_active Expired - Fee Related
- 1997-06-26 CA CA002257875A patent/CA2257875C/en not_active Expired - Fee Related
- 1997-06-26 AT AT97930236T patent/ATE285778T1/de not_active IP Right Cessation
- 1997-06-26 AU AU34119/97A patent/AU734702B2/en not_active Ceased
- 1997-06-26 ES ES97930236T patent/ES2234021T3/es not_active Expired - Lifetime
- 1997-06-26 WO PCT/US1997/011220 patent/WO1998000145A1/en not_active Ceased
- 1997-06-26 EP EP97930236A patent/EP0909173B1/de not_active Expired - Lifetime
- 1997-06-26 JP JP10504321A patent/JP2000514798A/ja not_active Ceased
- 1997-07-29 US US08/902,503 patent/US5916885A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000514798A (ja) | 2000-11-07 |
| DE69732108D1 (de) | 2005-02-03 |
| CA2257875A1 (en) | 1998-01-08 |
| EP0909173A1 (de) | 1999-04-21 |
| CA2257875C (en) | 2007-08-28 |
| DE69732108T2 (de) | 2005-12-22 |
| EP0909173B1 (de) | 2004-12-29 |
| US5843936A (en) | 1998-12-01 |
| AU734702B2 (en) | 2001-06-21 |
| ES2234021T3 (es) | 2005-06-16 |
| WO1998000145A1 (en) | 1998-01-08 |
| AU3411997A (en) | 1998-01-21 |
| US5916885A (en) | 1999-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |