ATE287704T1 - Orodispersible tablette mit hoher homogenität und herstellungsverfahren dafür - Google Patents

Orodispersible tablette mit hoher homogenität und herstellungsverfahren dafür

Info

Publication number
ATE287704T1
ATE287704T1 AT02796830T AT02796830T ATE287704T1 AT E287704 T1 ATE287704 T1 AT E287704T1 AT 02796830 T AT02796830 T AT 02796830T AT 02796830 T AT02796830 T AT 02796830T AT E287704 T1 ATE287704 T1 AT E287704T1
Authority
AT
Austria
Prior art keywords
agent
excipients
grains
microgranules
seconds
Prior art date
Application number
AT02796830T
Other languages
English (en)
Inventor
Edouard Gendrot
Nourredine Nouri
Pascal Suplie
Original Assignee
Ethypharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm Sa filed Critical Ethypharm Sa
Application granted granted Critical
Publication of ATE287704T1 publication Critical patent/ATE287704T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Seasonings (AREA)
AT02796830T 2001-11-05 2002-10-28 Orodispersible tablette mit hoher homogenität und herstellungsverfahren dafür ATE287704T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0114269A FR2831820B1 (fr) 2001-11-05 2001-11-05 Comprime orodispersible presentant une grande homogeneite et son procede de preparation
PCT/FR2002/003690 WO2003039520A1 (fr) 2001-11-05 2002-10-28 Comprime orodispersible presentant une grande homogeneite et son procede de preparation

Publications (1)

Publication Number Publication Date
ATE287704T1 true ATE287704T1 (de) 2005-02-15

Family

ID=8869063

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02796830T ATE287704T1 (de) 2001-11-05 2002-10-28 Orodispersible tablette mit hoher homogenität und herstellungsverfahren dafür

Country Status (10)

Country Link
US (1) US20050019391A1 (de)
EP (1) EP1441704B1 (de)
JP (2) JP4749668B2 (de)
AT (1) ATE287704T1 (de)
CA (1) CA2465753C (de)
DE (1) DE60202794T2 (de)
DK (1) DK1441704T3 (de)
ES (1) ES2236617T3 (de)
FR (1) FR2831820B1 (de)
WO (1) WO2003039520A1 (de)

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US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
ATE346590T1 (de) * 2001-07-26 2006-12-15 Ethypharm Sa Umgehüllte allylamine oder benzylamine enthaltende granulate, verfahren zur herstellung und in der mundhöhle dispergierbare tabletten enthaltend die umgehüllten granulate
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
FR2831820B1 (fr) * 2001-11-05 2004-08-20 Ethypharm Sa Comprime orodispersible presentant une grande homogeneite et son procede de preparation
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
JP4664924B2 (ja) 2003-12-02 2011-04-06 ウーツェーベー ファルマ ゲーエムベーハー 中枢神経因性疼痛の治療のためのペプチド化合物の新規使用
EP1604655A1 (de) 2004-06-09 2005-12-14 Schwarz Pharma Ag Neue Verwendung von Peptidverbindungen zur Behandlung von Trigeminusneuralgie
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ728442A (en) 2004-10-21 2018-05-25 Adare Pharmaceuticals Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
DE102005009240A1 (de) 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
EA019757B1 (ru) 2006-06-15 2014-06-30 ЮСиБи ФАРМА ГМБХ Фармацевтическая композиция с синергетическим противосудорожным эффектом
DE602006014601D1 (de) 2006-08-17 2010-07-08 Gumlink As Harzverkapselter intensivsüsstoff
KR20160083132A (ko) * 2007-06-06 2016-07-11 바스프 에스이 급속 붕해 정제의 제조를 위한 제약 제제
US8685457B2 (en) * 2007-06-06 2014-04-01 Basf Se Pharmaceutical formulation for the production of rapidly disintegrating tablets
JP2010529073A (ja) * 2007-06-06 2010-08-26 ビーエーエスエフ ソシエタス・ヨーロピア チュアブル錠及びトローチ剤製造のための医薬製剤
CN102083410B (zh) * 2007-06-06 2013-04-17 巴斯夫欧洲公司 用于制备迅速崩解的片剂的药物制剂
AU2009240586A1 (en) * 2008-04-24 2009-10-29 Evestra, Inc. Oral contraceptive dosage forms comprising a progestogen dispersed in an enteric polymer and further comprising an estrogen
EP2385769A4 (de) * 2008-12-15 2014-08-20 Valeant Pharmaceuticals Luxembourg S R L Schnell lösliche vitaminformulierung und verfahren zu ihrer anwendung
MX2011009053A (es) * 2009-03-09 2012-04-02 Spi Pharma Inc Excipientes de compresion directa con alta capacidad de compactacion y durables y sistemas de excipiente.
EP2418861A4 (de) * 2009-04-14 2013-01-09 Panasonic Corp Videoanzeigeeinrichtung, brille zum betrachten von video und mit einer videoanzeigeeinrichtung und brille zum betrachten von video ausgestattetes system
NZ624922A (en) 2009-10-01 2016-05-27 Adare Pharmaceuticals Inc Orally administered corticosteroid compositions
AU2010325746B2 (en) 2009-12-02 2016-02-25 Adare Pharmaceuticals S.R.L. Fexofenadine microcapsules and compositions containing them
WO2011112771A1 (en) * 2010-03-11 2011-09-15 Rich Vitamins Llc Quick dissolve nutritional powder
FR2962550B1 (fr) 2010-07-06 2013-06-14 Ethypharm Sa Methode pour lutter contre la soumission chimique, utilisation d'agent colorant pour lutter contre la soumission chimique et composition pharmaceutique permettant la mise en oeuvre de la methode
FR2962331B1 (fr) 2010-07-06 2020-04-24 Ethypharm Forme pharmaceutique pour lutter contre la soumission chimique, methode la mettant en oeuvre
FR2999432B1 (fr) 2012-12-17 2014-12-12 Ethypharm Sa Comprimes orodispersibles obtenus par compression moulage
WO2015034678A2 (en) * 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
TWI728172B (zh) 2016-08-18 2021-05-21 美商愛戴爾製藥股份有限公司 治療嗜伊紅性食道炎之方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2236483B1 (de) * 1973-07-12 1976-11-12 Choay Sa
US4199610A (en) * 1978-09-13 1980-04-22 The Procter & Gamble Company Non-hygroscopic dry instant beverage mixes
JPS57500432A (de) * 1980-03-20 1982-03-11
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
JP3122141B2 (ja) * 1994-01-31 2001-01-09 山之内製薬株式会社 口腔内溶解型圧縮成型物及びその製造法
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
PT922464E (pt) * 1996-07-12 2005-07-29 Daiichi Seiyaku Co Materiais moldados por compressao rapidamente desintegraveis e processo para a sua producao
JP4939680B2 (ja) * 1997-05-27 2012-05-30 武田薬品工業株式会社 固形製剤
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
US6270790B1 (en) * 1998-08-18 2001-08-07 Mxneil-Ppc, Inc. Soft, convex shaped chewable tablets having reduced friability
FR2784895B1 (fr) * 1998-10-23 2004-12-17 Gattefosse Ets Sa Comprime a croquer a gout masque et liberation immediate du principe actif et procede de fabrication
JP2000178183A (ja) * 1998-12-17 2000-06-27 Lion Corp 固形製剤及びその製造方法
FR2790387B1 (fr) * 1999-03-01 2001-05-18 Prographarm Laboratoires Comprime orodispersible presentant une faible friabilite et son procede de preparation
JP2001058944A (ja) * 1999-06-18 2001-03-06 Takeda Chem Ind Ltd 速崩壊性固形製剤
FR2816507B1 (fr) * 2000-11-16 2003-02-28 Ethypharm Lab Prod Ethiques Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules
FR2831820B1 (fr) * 2001-11-05 2004-08-20 Ethypharm Sa Comprime orodispersible presentant une grande homogeneite et son procede de preparation

Also Published As

Publication number Publication date
DK1441704T3 (da) 2005-05-30
EP1441704B1 (de) 2005-01-26
JP4749668B2 (ja) 2011-08-17
DE60202794D1 (de) 2005-03-03
CA2465753A1 (fr) 2003-05-15
US20050019391A1 (en) 2005-01-27
FR2831820B1 (fr) 2004-08-20
JP2011006482A (ja) 2011-01-13
FR2831820A1 (fr) 2003-05-09
EP1441704A1 (de) 2004-08-04
WO2003039520A1 (fr) 2003-05-15
CA2465753C (fr) 2013-05-14
DE60202794T2 (de) 2006-05-18
JP2005511589A (ja) 2005-04-28
ES2236617T3 (es) 2005-07-16

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties