ATE287734T1 - Radionukleiide assoziierte nukleotid- polyphosphate zur bilddarstellung von tumoren - Google Patents

Radionukleiide assoziierte nukleotid- polyphosphate zur bilddarstellung von tumoren

Info

Publication number
ATE287734T1
ATE287734T1 AT98918880T AT98918880T ATE287734T1 AT E287734 T1 ATE287734 T1 AT E287734T1 AT 98918880 T AT98918880 T AT 98918880T AT 98918880 T AT98918880 T AT 98918880T AT E287734 T1 ATE287734 T1 AT E287734T1
Authority
AT
Austria
Prior art keywords
associated nucleotide
imaging tumors
radionuclide
imaging agents
tumor imaging
Prior art date
Application number
AT98918880T
Other languages
English (en)
Inventor
David R Elmaleh
John W Babich
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of ATE287734T1 publication Critical patent/ATE287734T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
AT98918880T 1997-05-01 1998-04-30 Radionukleiide assoziierte nukleotid- polyphosphate zur bilddarstellung von tumoren ATE287734T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/846,999 US6187286B1 (en) 1996-12-27 1997-05-01 Tumor imaging agents, methods and kits
PCT/US1998/008776 WO1998048849A1 (en) 1997-05-01 1998-04-30 Radionuclide associated with nucleotide polyphosphate as tumor imaging agents

Publications (1)

Publication Number Publication Date
ATE287734T1 true ATE287734T1 (de) 2005-02-15

Family

ID=25299526

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98918880T ATE287734T1 (de) 1997-05-01 1998-04-30 Radionukleiide assoziierte nukleotid- polyphosphate zur bilddarstellung von tumoren

Country Status (8)

Country Link
US (1) US6187286B1 (de)
EP (1) EP0975373B1 (de)
JP (2) JP2002500639A (de)
AT (1) ATE287734T1 (de)
AU (1) AU751889B2 (de)
CA (1) CA2287838C (de)
DE (1) DE69828779T2 (de)
WO (1) WO1998048849A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067111B1 (en) 1999-10-25 2006-06-27 Board Of Regents, University Of Texas System Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
IL153218A0 (en) 2000-06-02 2003-07-06 Univ Texas Ethylenedicysteine (ec) -drug conjugates
US7223541B2 (en) * 2001-08-29 2007-05-29 Ge Healthcare Bio-Sciences Corp. Terminal-phosphate-labeled nucleotides and methods of use
US7560254B2 (en) 2001-08-29 2009-07-14 Ge Healthcare Bio-Sciences Corp. Allele specific primer extension
WO2003020734A2 (en) * 2001-08-29 2003-03-13 Amersham Biosciences Corp Labeled nucleoside polyphosphates
US7052839B2 (en) * 2001-08-29 2006-05-30 Amersham Biosciences Corp Terminal-phosphate-labeled nucleotides and methods of use
US7033762B2 (en) 2001-08-29 2006-04-25 Amersham Biosciences Corp Single nucleotide amplification and detection by polymerase
US7256019B2 (en) * 2001-08-29 2007-08-14 Ge Healthcare Bio-Sciences Corp. Terminal phosphate blocked nucleoside polyphosphates
US9050378B2 (en) * 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
US8758723B2 (en) * 2006-04-19 2014-06-24 The Board Of Regents Of The University Of Texas System Compositions and methods for cellular imaging and therapy
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
DE102007036559B4 (de) * 2007-08-03 2015-02-19 Siemens Aktiengesellschaft Verfahren zur Detektion und Lokalisierung eines metabolischen Markers, einschließlich Röntgen-CT-System und Röntgen-Projektions-System zur Durchführung dieses Verfahrens
EP3231804B1 (de) 2008-03-21 2021-03-03 The General Hospital Corporation Verbindungen und zusammensetzungen für den nachweis und die behandlung von morbus alzheimer und verwandten erkrankungen
WO2017139419A1 (en) 2016-02-11 2017-08-17 Qiagen Waltham, Inc. Polyphenolic additives in sequencing-by-synthesis

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
US4440738A (en) * 1982-06-10 1984-04-03 Mallinckrodt, Inc. Stable radiographic imaging agents
US4510125A (en) * 1982-12-08 1985-04-09 Mallinckrodt, Inc. Process for making lyophilized radiographic imaging kit
US5556982A (en) * 1985-01-14 1996-09-17 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
ATE66469T1 (de) * 1985-01-14 1991-09-15 Neorx Corp Metall-radionuklid markiertes protein fuer diagnose und therapie.
US5202451A (en) * 1988-02-17 1993-04-13 Neorx Corporation Anchimeric radiometal chelating compounds
US5602244A (en) * 1988-05-26 1997-02-11 Competitive Technologies, Inc. Polynucleotide phosphorodithioate compounds
US5070877A (en) * 1988-08-11 1991-12-10 Medco Research, Inc. Novel method of myocardial imaging
GB8906708D0 (en) * 1989-03-23 1989-05-10 Foxwell Brian M J Improvements relating to the radiolabelling of proteins
DE69634448T2 (de) * 1995-12-28 2006-04-13 The General Hospital Corp., Boston Verbindungen, verfahren und kits zur bildgebung des kardiovaskulären systems und von thromben

Also Published As

Publication number Publication date
CA2287838A1 (en) 1998-11-05
WO1998048849A9 (en) 1999-04-22
EP0975373A1 (de) 2000-02-02
DE69828779T2 (de) 2006-01-05
AU751889B2 (en) 2002-08-29
AU7171898A (en) 1998-11-24
JP2007297404A (ja) 2007-11-15
JP2002500639A (ja) 2002-01-08
WO1998048849A1 (en) 1998-11-05
EP0975373B1 (de) 2005-01-26
CA2287838C (en) 2007-11-20
US6187286B1 (en) 2001-02-13
DE69828779D1 (de) 2005-03-03

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