ATE287953T1 - Persephin und verwandte wachstumsfaktoren - Google Patents
Persephin und verwandte wachstumsfaktorenInfo
- Publication number
- ATE287953T1 ATE287953T1 AT97917509T AT97917509T ATE287953T1 AT E287953 T1 ATE287953 T1 AT E287953T1 AT 97917509 T AT97917509 T AT 97917509T AT 97917509 T AT97917509 T AT 97917509T AT E287953 T1 ATE287953 T1 AT E287953T1
- Authority
- AT
- Austria
- Prior art keywords
- persephin
- methods
- growth factors
- mouse
- neurturin
- Prior art date
Links
- 102100036660 Persephin Human genes 0.000 title abstract 5
- 108010070453 persephin Proteins 0.000 title abstract 5
- 239000003102 growth factor Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 230000010558 Gene Alterations Effects 0.000 abstract 1
- 102000034615 Glial cell line-derived neurotrophic factor Human genes 0.000 abstract 1
- 108091010837 Glial cell line-derived neurotrophic factor Proteins 0.000 abstract 1
- 101001136669 Mus musculus Persephin Proteins 0.000 abstract 1
- 102100021584 Neurturin Human genes 0.000 abstract 1
- 108010015406 Neurturin Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 101001136668 Rattus norvegicus Persephin Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hospice & Palliative Care (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61594496A | 1996-03-14 | 1996-03-14 | |
| PCT/US1997/003461 WO1997033911A1 (en) | 1996-03-14 | 1997-03-14 | Persephin and related growth factors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE287953T1 true ATE287953T1 (de) | 2005-02-15 |
Family
ID=24467424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97917509T ATE287953T1 (de) | 1996-03-14 | 1997-03-14 | Persephin und verwandte wachstumsfaktoren |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US6232449B1 (de) |
| EP (1) | EP0886651B1 (de) |
| JP (1) | JP2000507813A (de) |
| AT (1) | ATE287953T1 (de) |
| AU (1) | AU716846B2 (de) |
| CA (1) | CA2225913A1 (de) |
| DE (1) | DE69732350T2 (de) |
| ES (1) | ES2237793T3 (de) |
| NZ (1) | NZ329482A (de) |
| WO (1) | WO1997033911A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5739307A (en) * | 1995-08-28 | 1998-04-14 | Washington University | Polynucleotide encoding neurturin neurotrophic factor |
| US6716600B1 (en) * | 1996-03-14 | 2004-04-06 | Washington University | Persephin and related growth factors |
| DE69732350T2 (de) * | 1996-03-14 | 2005-12-22 | Washington University | Persephin und verwandte wachstumsfaktoren |
| US6222022B1 (en) * | 1996-03-14 | 2001-04-24 | Washington University | Persephin and related growth factors |
| DE19816186A1 (de) * | 1998-04-14 | 1999-10-21 | Univ Muenchen L Maximilians | GDNF-kodierende DNA, Teile davon und GDNF-Varianten |
| WO2000006731A2 (en) * | 1998-07-31 | 2000-02-10 | Washington University | PERSEPHIN ARF, A PROTEIN ENCODED BY UNSPLICED PERSEPHIN mRNA |
| PL346298A1 (en) * | 1998-08-21 | 2002-01-28 | Hannu Sariola | The use of glial cell line-derived neurotrophic factor family-related compounds for regulating spermatogenesis and for preparing male contraceptives |
| US6284540B1 (en) * | 1998-09-29 | 2001-09-04 | Washington University | Artemin, a novel neurotrophic factor |
| FI991197A0 (fi) * | 1999-05-27 | 1999-05-27 | Mart Saarma | Neurotrooppiset tekijät lantionalueen ääreishermoston toimintahäiriön hoitamisessa |
| US6866851B1 (en) * | 1999-12-28 | 2005-03-15 | Washington University | GFRα1-RET specific agonists and methods therefor |
| FI20000403A0 (fi) * | 2000-02-22 | 2000-02-22 | Hannu Sariola | GDNF perhesukuisten yhdisteiden käyttö kivessyövän hoitoon tarkoitettujen tuotteiden valmistamiseksi |
| WO2010144696A1 (en) | 2009-06-11 | 2010-12-16 | Burnham Institute For Medical Research | Directed differentiation of stem cells |
| US9821026B2 (en) * | 2012-06-28 | 2017-11-21 | Instituto De Medicina Molecular | Use of RET agonist molecules for haematopoietic stem cell expansion protocols and transplantation therapy and a RET agonist kit |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5141856A (en) * | 1989-01-05 | 1992-08-25 | Synergen, Inc. | Expression of purified ciliary neurotrophic factor |
| US5011914A (en) * | 1989-01-05 | 1991-04-30 | Collins Franklin D | Purified ciliary neurotrophic factor |
| US5260417A (en) | 1989-04-03 | 1993-11-09 | Genetics Institute, Inc. | Megakaryocyte growth promoting activity protein |
| US5235043A (en) * | 1990-04-06 | 1993-08-10 | Synergen, Inc. | Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins |
| AU679167B2 (en) * | 1991-09-20 | 1997-06-26 | Amgen, Inc. | Glial derived neurotrophic factor |
| EP0721464A4 (de) | 1993-09-01 | 1998-12-30 | Start Technology Partnership | Neuronenregulationsfaktor zur erhöhung der überlebensrate von neuronen |
| AU1443095A (en) * | 1993-12-22 | 1995-07-10 | University Of Medicine And Dentistry Of New Jersey | Novel nucleic acid sequences isolated from glial cells |
| US5739307A (en) * | 1995-08-28 | 1998-04-14 | Washington University | Polynucleotide encoding neurturin neurotrophic factor |
| DE69732350T2 (de) * | 1996-03-14 | 2005-12-22 | Washington University | Persephin und verwandte wachstumsfaktoren |
-
1997
- 1997-03-14 DE DE69732350T patent/DE69732350T2/de not_active Expired - Lifetime
- 1997-03-14 WO PCT/US1997/003461 patent/WO1997033911A1/en not_active Ceased
- 1997-03-14 AT AT97917509T patent/ATE287953T1/de not_active IP Right Cessation
- 1997-03-14 AU AU25804/97A patent/AU716846B2/en not_active Ceased
- 1997-03-14 US US08/981,739 patent/US6232449B1/en not_active Expired - Fee Related
- 1997-03-14 ES ES97917509T patent/ES2237793T3/es not_active Expired - Lifetime
- 1997-03-14 EP EP97917509A patent/EP0886651B1/de not_active Expired - Lifetime
- 1997-03-14 JP JP9532677A patent/JP2000507813A/ja active Pending
- 1997-03-14 NZ NZ329482A patent/NZ329482A/xx unknown
- 1997-03-14 US US09/220,527 patent/US6692943B1/en not_active Expired - Lifetime
- 1997-03-14 CA CA002225913A patent/CA2225913A1/en not_active Abandoned
-
1998
- 1998-07-31 US US09/128,026 patent/US6403335B1/en not_active Expired - Lifetime
- 1998-12-24 US US09/220,616 patent/US6645937B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU716846B2 (en) | 2000-03-09 |
| ES2237793T3 (es) | 2005-08-01 |
| EP0886651A4 (de) | 2001-01-10 |
| NZ329482A (en) | 2000-05-26 |
| CA2225913A1 (en) | 1997-09-18 |
| US6645937B1 (en) | 2003-11-11 |
| DE69732350T2 (de) | 2005-12-22 |
| US6692943B1 (en) | 2004-02-17 |
| AU2580497A (en) | 1997-10-01 |
| WO1997033911A1 (en) | 1997-09-18 |
| DE69732350D1 (de) | 2005-03-03 |
| US6403335B1 (en) | 2002-06-11 |
| US6232449B1 (en) | 2001-05-15 |
| EP0886651B1 (de) | 2005-01-26 |
| EP0886651A1 (de) | 1998-12-30 |
| JP2000507813A (ja) | 2000-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |