ATE290016T1 - Photoprotein mit verbesserter biolumineszenz - Google Patents

Photoprotein mit verbesserter biolumineszenz

Info

Publication number
ATE290016T1
ATE290016T1 AT02023452T AT02023452T ATE290016T1 AT E290016 T1 ATE290016 T1 AT E290016T1 AT 02023452 T AT02023452 T AT 02023452T AT 02023452 T AT02023452 T AT 02023452T AT E290016 T1 ATE290016 T1 AT E290016T1
Authority
AT
Austria
Prior art keywords
photoprotein
iii
chosen
sequence
region
Prior art date
Application number
AT02023452T
Other languages
English (en)
Inventor
Maria Foti
Stefan Lohmer
Original Assignee
Axxam S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axxam S R L filed Critical Axxam S R L
Application granted granted Critical
Publication of ATE290016T1 publication Critical patent/ATE290016T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Dental Preparations (AREA)
AT02023452T 2002-10-21 2002-10-21 Photoprotein mit verbesserter biolumineszenz ATE290016T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02023452A EP1413584B1 (de) 2002-10-21 2002-10-21 Photoprotein mit verbesserter Biolumineszenz

Publications (1)

Publication Number Publication Date
ATE290016T1 true ATE290016T1 (de) 2005-03-15

Family

ID=32049982

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02023452T ATE290016T1 (de) 2002-10-21 2002-10-21 Photoprotein mit verbesserter biolumineszenz

Country Status (21)

Country Link
US (1) US7601805B2 (de)
EP (1) EP1413584B1 (de)
JP (1) JP4459058B2 (de)
KR (1) KR20050053783A (de)
CN (1) CN1317299C (de)
AT (1) ATE290016T1 (de)
AU (1) AU2003287962B2 (de)
BR (1) BR0306589A (de)
CA (1) CA2503145A1 (de)
DE (1) DE60203123T2 (de)
DK (1) DK1413584T3 (de)
ES (1) ES2237643T3 (de)
HR (1) HRP20050354A2 (de)
IL (1) IL168158A (de)
MX (1) MXPA05004148A (de)
NO (1) NO20051921L (de)
PL (1) PL376323A1 (de)
RS (1) RS54004A (de)
RU (1) RU2340629C2 (de)
WO (1) WO2004035620A1 (de)
ZA (1) ZA200503197B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10342670A1 (de) * 2003-09-16 2005-04-21 Bayer Healthcare Ag Isoliertes Photoprotein mtClytin, sowie dessen Verwendung
EP1700865A1 (de) * 2005-03-11 2006-09-13 AXXAM S.r.l. Photoproteine mit erhöhter Biolumineszenz und deren Verwendung als intrazelluläre Calcium-Indikatoren
EP1808441A1 (de) * 2006-01-11 2007-07-18 AXXAM S.p.A. Lumineszierende Stammzellen, transgene Säugetiere und deren Verwendung
EP1973938B1 (de) * 2006-01-11 2011-04-06 Axxam S.P.A. Leuchtende stammzellen und ihre verwendung
JP2009540299A (ja) 2006-06-05 2009-11-19 カリフォルニア インスティテュート オブ テクノロジー リアルタイムマイクロアレイ
US8637436B2 (en) 2006-08-24 2014-01-28 California Institute Of Technology Integrated semiconductor bioarray
US11001881B2 (en) 2006-08-24 2021-05-11 California Institute Of Technology Methods for detecting analytes
JP5374840B2 (ja) 2006-07-20 2013-12-25 Ｊｎｃ株式会社 カルシウム結合発光蛋白質、それをコードする遺伝子およびその用途
US11525156B2 (en) 2006-07-28 2022-12-13 California Institute Of Technology Multiplex Q-PCR arrays
US8048626B2 (en) 2006-07-28 2011-11-01 California Institute Of Technology Multiplex Q-PCR arrays
US11560588B2 (en) 2006-08-24 2023-01-24 California Institute Of Technology Multiplex Q-PCR arrays
GB0625678D0 (en) 2006-12-21 2007-01-31 Lux Biotechnology Ltd Composition and method for detection of demineralisation
US8431698B2 (en) * 2007-08-29 2013-04-30 Biolume Inc. Bioluminescent endoscopy methods and compounds
DK2324127T3 (en) 2008-08-10 2015-04-27 Kuakini Medical Ct A method of using FOXO3A polymorphisms and haplotypes for predicting and healthy aging and longevity
JP5304275B2 (ja) * 2009-01-29 2013-10-02 Ｊｎｃ株式会社 アポクライティン−ｉｉをコードするコドン最適化核酸およびその使用方法
SG172321A1 (en) * 2009-01-29 2011-07-28 Commw Scient Ind Res Org Measuring g protein coupled receptor activation
US8669103B2 (en) * 2010-11-02 2014-03-11 Promega Corporation Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
PT2635583E (pt) * 2010-11-02 2015-09-11 Promega Corp Derivados da coelenterazina e métodos de utilização da mesma
CA2822594A1 (en) 2010-12-24 2012-06-28 Otsuka Pharmaceutical Co., Ltd. Bioassay method for detecting physiologically active substance
AU2013204332B2 (en) 2012-04-16 2015-07-16 Commonwealth Scientific And Industrial Research Organisation Methods and systems for detecting an analyte or classifying a sample
US9927430B2 (en) 2014-01-29 2018-03-27 Promega Corporation Pro-substrates for live cell applications
WO2015116867A1 (en) 2014-01-29 2015-08-06 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
US9708647B2 (en) 2015-03-23 2017-07-18 Insilixa, Inc. Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
US9499861B1 (en) 2015-09-10 2016-11-22 Insilixa, Inc. Methods and systems for multiplex quantitative nucleic acid amplification
WO2017155858A1 (en) 2016-03-07 2017-09-14 Insilixa, Inc. Nucleic acid sequence identification using solid-phase cyclic single base extension
AU2017358067B2 (en) 2016-11-14 2024-04-18 PPB Technology Pty Ltd Protease sensor molecules
GB201700317D0 (en) 2017-01-09 2017-02-22 Calcivis Ltd Detection device
CA3071994A1 (en) 2017-08-08 2019-02-14 Commonwealth Scientific And Industrial Research Organisation Carbohydrate sensors
WO2019241319A1 (en) * 2018-06-13 2019-12-19 The Research Foundation For The State University Of New York Chromatic bioluminescence as a cellular level readout system of neural activity
JP7687957B2 (ja) 2019-03-14 2025-06-03 インシリクサ， インコーポレイテッド 時間ゲート蛍光ベースの検出のための方法およびシステム
USD1042180S1 (en) 2020-05-28 2024-09-17 Calcivis Limited Dental detection device
RU2770490C1 (ru) * 2021-07-14 2022-04-18 Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр "Красноярский научный центр Сибирского отделения Российской академии наук" Рекомбинантная плазмидная ДНК pET19b-Surv-OL, обеспечивающая синтез гибридного белка сурвивин-обелин (Surv-OL) и гибридный белок, связываемый анти-сурвивин антителами и обладающий биолюминесцентной активностью

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2114175C1 (ru) * 1993-09-14 1998-06-27 Институт белка РАН Способ клонирования нуклеиновых кислот

Also Published As

Publication number Publication date
AU2003287962A1 (en) 2004-05-04
IL168158A (en) 2010-06-16
ES2237643T3 (es) 2005-08-01
RU2005111772A (ru) 2005-09-10
DK1413584T3 (da) 2005-07-04
JP2006517784A (ja) 2006-08-03
PL376323A1 (en) 2005-12-27
CN1317299C (zh) 2007-05-23
HRP20050354A2 (en) 2005-08-31
CA2503145A1 (en) 2004-04-29
WO2004035620A1 (en) 2004-04-29
US7601805B2 (en) 2009-10-13
MXPA05004148A (es) 2005-08-03
KR20050053783A (ko) 2005-06-08
BR0306589A (pt) 2004-11-30
AU2003287962B2 (en) 2010-06-17
US20070065818A1 (en) 2007-03-22
JP4459058B2 (ja) 2010-04-28
DE60203123T2 (de) 2005-07-21
ZA200503197B (en) 2006-06-28
RS54004A (sr) 2006-10-27
CN1705680A (zh) 2005-12-07
HRP20050354B1 (de) 2007-01-31
RU2340629C2 (ru) 2008-12-10
DE60203123D1 (de) 2005-04-07
EP1413584A1 (de) 2004-04-28
EP1413584B1 (de) 2005-03-02
NO20051921L (no) 2005-05-23

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