ATE290103T1 - Verfahren zur herstellung eines biochip sowie biochip - Google Patents

Verfahren zur herstellung eines biochip sowie biochip

Info

Publication number: ATE290103T1
Authority: AT; Austria
Prior art keywords: biochip; pyrrole; functionalised; microtroughs; electropolymerisation
Prior art date: 1998-12-16

Application number

AT99958329T

Other languages

English (en)

Inventor

Charles Rosilio

Patrice Caillat

Original Assignee

Commissariat Energie Atomique

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-16

Filing date

1999-12-15

Publication date

2005-03-15

1999-12-15 Application filed by Commissariat Energie Atomique filed Critical Commissariat Energie Atomique

2005-03-15 Application granted granted Critical

2005-03-15 Publication of ATE290103T1 publication Critical patent/ATE290103T1/de

Links

238000000018 DNA microarray Methods 0.000 title abstract 5
238000004519 manufacturing process Methods 0.000 title 1
KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 6
238000000034 method Methods 0.000 abstract 3
229920001577 copolymer Polymers 0.000 abstract 2
239000000758 substrate Substances 0.000 abstract 2
108091034117 Oligonucleotide Proteins 0.000 abstract 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
229920001940 conductive polymer Polymers 0.000 abstract 1
230000000977 initiatory effect Effects 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
230000001737 promoting effect Effects 0.000 abstract 1
239000000523 sample Substances 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
- B01J2219/00317—Microwell devices, i.e. having large numbers of wells
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00653—Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00709—Type of synthesis
- B01J2219/00713—Electrochemical synthesis
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Urology & Nephrology (AREA)
Biotechnology (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cell Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Peptides Or Proteins (AREA)

AT99958329T 1998-12-16 1999-12-15 Verfahren zur herstellung eines biochip sowie biochip ATE290103T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9815883A FR2787582B1 (fr)	1998-12-16	1998-12-16	Procede de fabrication d'une biopuce et biopuce
PCT/FR1999/003141 WO2000036145A1 (fr)	1998-12-16	1999-12-15	Procede de fabrication d'une biopuce et biopuce

Publications (1)

Publication Number	Publication Date
ATE290103T1 true ATE290103T1 (de)	2005-03-15

Family

ID=9534034

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99958329T ATE290103T1 (de)	1998-12-16	1999-12-15	Verfahren zur herstellung eines biochip sowie biochip

Country Status (7)

Country	Link
US (1)	US6803228B1 (de)
EP (1)	EP1141391B1 (de)
JP (1)	JP2002532699A (de)
AT (1)	ATE290103T1 (de)
DE (1)	DE69924010T2 (de)
FR (1)	FR2787582B1 (de)
WO (1)	WO2000036145A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2789401B1 (fr) *	1999-02-08	2003-04-04	Cis Bio Int	Procede de fabrication de matrices de ligands adresses sur un support
US7407746B2 (en) *	2001-02-08	2008-08-05	Ngk Insulators, Ltd.	Biochip and method for producing the same
FR2821575B1 (fr) *	2001-03-02	2003-10-24	Commissariat Energie Atomique	Procede de greffage organique localise sans masque sur des protions conductrices ou semiconductrices de surfaces composites
FR2824143B1 (fr) *	2001-04-27	2003-06-27	Commissariat Energie Atomique	Utilisations d'un dispositif miniature de separation et d'isolement d'objets biologiques et procedes mis en oeuvre
FR2823999B1 (fr) *	2001-04-27	2003-06-27	Commissariat Energie Atomique	Dispositif miniature de separation et d'isolement d'objets biologiques et utilisations
FR2831275B1 (fr) *	2001-10-18	2004-01-30	Commissariat Energie Atomique	Substrat revetu d'un film organique transparent et procede de fabrication
US6908678B2 (en)	2002-01-18	2005-06-21	Advanced Gene Technology, Corp.	Plastic slides for the fabrication of biochips
FR2847581B1 (fr) *	2002-11-21	2007-03-23	Commissariat Energie Atomique	Procede de fixation d'une proteine sur un polymere a base de pyrrole et son utilisation pour la fabrication d'un capteur
FR2849038B1 (fr) *	2002-12-19	2005-03-11	Apibio	Nouveaux pyrroles substitues avec des oligonucleotides, polymeres electroactifs et leurs utilisations
DE10305957A1 (de) *	2003-02-12	2005-02-03	GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF)	Elektrisch leitfähiger Kunststoff-Formkörper
FR2861609B1 (fr)	2003-10-31	2006-02-03	Commissariat Energie Atomique	Procede de repartition de gouttes d'un liquide d'interet sur une surface
US20060121501A1 (en) *	2004-10-22	2006-06-08	Stanislaw Burzynski	Method for immobilizing molecular probes to a semiconductor oxide surface
RU2298797C2 (ru) *	2005-05-03	2007-05-10	Закрытое акционерное общество Научный центр "БИАХРОМ"	Биочип и способ его изготовления
EP1939621B1 (de) *	2005-09-16	2014-11-19	Azbil Corporation	Verfahren zur herstellung des biochipsubstrats und verfahren zur herstellung des biochips
JP4755871B2 (ja) *	2005-09-16	2011-08-24	株式会社山武	バイオチップ用基板及びバイオチップの製造方法
JP4763402B2 (ja) *	2005-09-26	2011-08-31	株式会社山武	バイオチップの製造方法及びバイオチップ用基板
FR2903590B1 (fr) *	2006-07-13	2013-05-10	Commissariat Energie Atomique	Dispositif de prelevement cellulaire par contact
FR2927169B1 (fr) *	2008-02-05	2013-01-11	Commissariat Energie Atomique	Procede de fonctionnalisation de la surface d'un pore
US9079999B2 (en) *	2008-02-26	2015-07-14	Rigoberto Advincula	Methods for preparing polymer coatings by electrochemical grafting of polymer brushes, compositions prepared thereby and compositions for preparing the coatings
FR2959568A1 (fr)	2010-04-28	2011-11-04	Commissariat Energie Atomique	Procede et dispositif pour detecter et quantifier un analyte avec recyclage des reactifs
JP5704995B2 (ja) *	2011-03-31	2015-04-22	一般財団法人電力中央研究所	修飾電極、並びに、フローセル、測定装置、及び測定方法
CN103616426B (zh)	2013-12-02	2016-05-11	中国科学院上海应用物理研究所	一种用于快速生化分析的集成式的微流控电化学生物传感系统及其使用方法
WO2016043078A1 (ja) *	2014-09-19	2016-03-24	国立大学法人新潟大学	基質抗原同時検出バイオセンサ、電極、基質抗原同時検出方法、および、プログラム
GB2561173A (en)	2017-04-03	2018-10-10	Univ Dublin City	Microfluidic device for detection of analytes
US12496612B2 (en)	2021-01-08	2025-12-16	Surmodics, Inc.	Coating application system and methods for coating rotatable medical devices

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FR2480314A1 (fr) *	1980-04-11	1981-10-16	Commissariat Energie Atomique	Procede de depot par electropolymerisation de films minces organiques sur des surfaces conductrices de l'electricite en particulier sur des surfaces metalliques, et films minces ainsi obtenus
CA1311715C (en) *	1985-12-20	1992-12-22	Stanley J. Jasne	Method for the electropolymerization of conductive polymers
EP0402554B1 (de) *	1989-06-12	1993-11-18	Honda Giken Kogyo Kabushiki Kaisha	Verfahren zur Stabilisierung von elektroaktiven Polymerelektroden
US5846708A (en) *	1991-11-19	1998-12-08	Massachusetts Institiute Of Technology	Optical and electrical methods and apparatus for molecule detection
FR2696043B1 (fr) *	1992-09-18	1994-10-14	Commissariat Energie Atomique	Support à réseau d'éléments résistifs en polymère conducteur et son procédé de fabrication.
FR2703359B1 (fr) *	1993-03-31	1995-06-23	Cis Bio Int	Copolymère nucléotide(s)/polymère conducteur électronique ; son procédé de préparation et son utilisation .
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FR2714077B1 (fr) *	1993-12-21	1996-03-08	Lorraine Laminage	Procédé et bain de dépôt électrolytique de polypyrrole sur une surface de métal oxydable par électropolymérisation.
US6090947A (en) *	1996-02-26	2000-07-18	California Institute Of Technology	Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
US5810989A (en) *	1997-09-04	1998-09-22	Motorola, Inc.	Photoelectric synthesis of DNA or protein probe arrays
WO2000004193A1 (en) *	1998-07-20	2000-01-27	Yale University	Method for detecting nucleic acids using target-mediated ligation of bipartite primers
US6312896B1 (en) *	1998-09-17	2001-11-06	Igen Inaternational, Inc.	Assays for measuring nucleic acid binding proteins and enzyme activities

1998
- 1998-12-16 FR FR9815883A patent/FR2787582B1/fr not_active Expired - Fee Related
1999
- 1999-12-15 JP JP2000588392A patent/JP2002532699A/ja not_active Withdrawn
- 1999-12-15 DE DE69924010T patent/DE69924010T2/de not_active Expired - Fee Related
- 1999-12-15 EP EP99958329A patent/EP1141391B1/de not_active Expired - Lifetime
- 1999-12-15 US US09/868,043 patent/US6803228B1/en not_active Expired - Fee Related
- 1999-12-15 WO PCT/FR1999/003141 patent/WO2000036145A1/fr not_active Ceased
- 1999-12-15 AT AT99958329T patent/ATE290103T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
FR2787582B1 (fr)	2001-01-12
FR2787582A1 (fr)	2000-06-23
EP1141391B1 (de)	2005-03-02
EP1141391A1 (de)	2001-10-10
DE69924010T2 (de)	2006-04-13
DE69924010D1 (de)	2005-04-07
US6803228B1 (en)	2004-10-12
WO2000036145A1 (fr)	2000-06-22
JP2002532699A (ja)	2002-10-02

Legal Events

Date	Code	Title	Description
2005-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69924010D1 (de)	2005-04-07	Verfahren zur herstellung eines biochip sowie biochip
Khademhosseini et al.	2003	Direct patterning of protein‐and cell‐resistant polymeric monolayers and microstructures
US9090118B2 (en)	2015-07-28	Water pressure transfer method, a transfer film for water pressure transfer and a water pressure transfer article
CN101622542B (zh)	2013-06-12	微芯片的制造方法
US7220452B2 (en)	2007-05-22	Multilayer transfer patterning using polymer-on-polymer stamping
WO2004071644A3 (en)	2005-03-24	Surface modification of substrates
WO2002056021A3 (en)	2003-09-18	Polymer brushes for immobilizing molecules to a surface
WO2004106659A3 (en)	2006-06-08	Print methodology for applying polymer materials to roofing materials
DE60027309D1 (de)	2006-05-24	Polymerverzweigungen zur immobilisierung von molekülen auf oberflächen oder substraten, wobei die polymere wasserlösliche oder wasserdispergierbare segmente und sonden aufweisen
ATE403553T1 (de)	2008-08-15	Verfahren zur herstellung von bildern, die sehr beständig sind
DE60122578D1 (de)	2006-10-05	Verfahren und vorrichtung zur auswahl von tientenstrahldruck parametern
ATE230629T1 (de)	2003-01-15	Verfahren zur herstellung von strukturierten, selbstorganisierten molekularen monolagen einzelner molekularer spezies, insbesondere von substanzbibliotheken
DE602005022701D1 (de)	2010-09-16	Verfahren zur herstellung von mehrschichtigen cholesterischen optischen flüssigkristallkörpern
RU2741506C2 (ru)	2021-01-26	Способ получения штампа на основе полиорганосилоксанов, штамп на основе полиорганосилоксанов, применение его для процесса печати и способ впечатывания с его использованием
Park et al.	2007	Dual functional, polymeric self-assembled monolayers as a facile platform for construction of patterns of biomolecules
ATE254152T1 (de)	2003-11-15	Zusammensetzung, basierend auf vernetzbarem, wasserdispergierbarem acrylpolymer, verfahren und verwendung
ATE332340T1 (de)	2006-07-15	Verfahren zum drucken eines substrates und so erhaltener artikel
ATE393670T1 (de)	2008-05-15	Verfahren zur herstellung eines gegenstandes von verschiedenen aneinander klebenden, durch polyaddition härtenden silikonschichten
Jang et al.	2015	Agarose‐Assisted Micro‐Contact Printing for High‐Quality Biomolecular Micro‐Patterns
EP1724018A3 (de)	2008-07-09	Substrat und Vorrichtung für einen Bioassay sowie Verfahren zur Substratherstellung
EP2174765A3 (de)	2010-06-09	Verfahren zum Folienhinterspritzen
ATE388768T1 (de)	2008-03-15	Verfahren zur beschichtung von trägern
Wang et al.	2009	Patterning bio-molecules for cell attachment at single cell levels in PDMS microfluidic chips
ATE481641T1 (de)	2010-10-15	Verfahren zur fixierung eines proteins auf einem pyrrolpolymerisat, und dessen verwendung zur herstellung eines sensors
Lee et al.	2003	Pattern generation of cells on a polymeric surface using surface functionalization and microcontact printing