ATE290221T1 - Verfahren zur herstellung eines mr- kontrastmittels - Google Patents

Verfahren zur herstellung eines mr- kontrastmittels

Info

Publication number
ATE290221T1
ATE290221T1 AT00929722T AT00929722T ATE290221T1 AT E290221 T1 ATE290221 T1 AT E290221T1 AT 00929722 T AT00929722 T AT 00929722T AT 00929722 T AT00929722 T AT 00929722T AT E290221 T1 ATE290221 T1 AT E290221T1
Authority
AT
Austria
Prior art keywords
chamber
hydrogenation
inlet
liquid
solvent removal
Prior art date
Application number
AT00929722T
Other languages
English (en)
Inventor
Oskar Axelsson
Charlotte Olofsson
Axel Morgenstjerne
Georg Hansson
Haukur Johannesson
Jan H Ardenkjaer-Larsen
Original Assignee
Amersham Health As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10853772&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE290221(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amersham Health As filed Critical Amersham Health As
Application granted granted Critical
Publication of ATE290221T1 publication Critical patent/ATE290221T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
AT00929722T 1999-05-19 2000-05-17 Verfahren zur herstellung eines mr- kontrastmittels ATE290221T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9911681.6A GB9911681D0 (en) 1999-05-19 1999-05-19 Process
PCT/GB2000/001897 WO2000071166A2 (en) 1999-05-19 2000-05-17 Process

Publications (1)

Publication Number Publication Date
ATE290221T1 true ATE290221T1 (de) 2005-03-15

Family

ID=10853772

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00929722T ATE290221T1 (de) 1999-05-19 2000-05-17 Verfahren zur herstellung eines mr- kontrastmittels

Country Status (12)

Country Link
US (2) US6872380B2 (de)
EP (2) EP1179189B1 (de)
JP (1) JP2003500369A (de)
KR (1) KR100786476B1 (de)
CN (1) CN1203321C (de)
AT (1) ATE290221T1 (de)
AU (1) AU775374B2 (de)
CA (1) CA2372572C (de)
DE (1) DE60018408T2 (de)
GB (1) GB9911681D0 (de)
RU (1) RU2240828C2 (de)
WO (1) WO2000071166A2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6574496B1 (en) * 1999-05-19 2003-06-03 Amersham Health As Magnetic resonance imaging
GB9911679D0 (en) * 1999-05-19 1999-07-21 Nycomed Imaging As Magnetic resonance imaging
GB0219953D0 (en) * 2002-08-29 2002-10-02 Amersham Health R & D Ab An arrangement and a method for providing contrast agents
GB0219954D0 (en) * 2002-08-29 2002-10-02 Amersham Health R & D Ab Method and apparatus for producing contrast agents for magnetic resonance imaging
GB0219952D0 (en) * 2002-08-29 2002-10-02 Amersham Health R & D Ab Method and apparatus for producing contrast agents for magnetic resonance imaging
WO2007044867A2 (en) * 2005-10-11 2007-04-19 Huntington Medical Research Institutes Imaging agents and methods of use thereof
EP1986702A4 (de) * 2006-02-21 2012-12-12 Avrum Belzer Hyperpolarisationsverfahren, systeme und zusammensetzungen
WO2008086534A1 (en) 2007-01-11 2008-07-17 Huntington Medical Research Institutes Imaging agents and methods of use thereof
US20080275668A1 (en) * 2007-05-02 2008-11-06 General Electric Company Apparatus and method for fully automated closed system optical measurement of volume
GB2450316A (en) * 2007-06-18 2008-12-24 Univ York Hyperpolarizing nuclei
US20100233089A1 (en) * 2007-10-05 2010-09-16 Huntington Medical Research Institutes Imaging of genetic material with magnetic resonance
WO2009129265A1 (en) * 2008-04-14 2009-10-22 Huntington Medical Research Institutes Methods and apparatus for pasadena hyperpolarization
US8961933B2 (en) 2008-10-03 2015-02-24 Bracco Imaging S.P.A. Process for the preparation of aqueous solutions of hyperpolarized molecules
EP2374016B1 (de) 2008-12-10 2017-05-10 University of York Impulssequenzierung mit hyperpolarisierbaren kernen
EP2495333A1 (de) * 2011-03-03 2012-09-05 Roche Diagnostics GmbH Verfahren zum Herstellen eines Testelements zur Untersuchung einer Körperflüssigkeitsprobe und Testelement
WO2013167587A1 (en) 2012-05-07 2013-11-14 Albeda Innovation Aps Intra-operative cancer diagnosis based on a hyperpolarized marker
US9329246B2 (en) * 2012-10-03 2016-05-03 Bruker Biospin Ag Method for hyperpolarization transfer in the liquid state
US9566354B2 (en) 2012-10-23 2017-02-14 Vanderbilt University Systems and methods of performing NMR spectroscopy and MRI
CN103432977B (zh) * 2013-08-29 2015-01-07 中国科学院武汉物理与数学研究所 一种用于磁共振造影剂预极化的级联容器及其方法
WO2015063020A1 (en) 2013-10-28 2015-05-07 Bracco Imaging Spa Process for the preparation of hyperpolarized carboxylate compounds
WO2017009856A1 (en) * 2015-07-16 2017-01-19 Aspect Imaging Ltd. Method and system for hyperpolarization of materials used in magnetic resonance imaging
WO2022266662A1 (en) * 2021-06-17 2022-12-22 University Of Florida Research Foundation, Inc. Methods and systems for producing hyperpolarized fluid samples
EP4141464A1 (de) * 2021-08-26 2023-03-01 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Breitbandverfahren zur signalverstärkung von magnetresonanzkontrastmitteln innerhalb von sekunden und deren reinigung
JP2025514650A (ja) * 2022-04-07 2025-05-09 アメリカ合衆国 Ｍｒｉプローブの調製および送達のための注入装置
DE102023133847A1 (de) * 2023-12-04 2025-06-05 Albert-Ludwigs-Universität Freiburg, Körperschaft des öffentlichen Rechts Hyperpolarisator, Hyperpolarisationsanordnung, Verfahren zur Hyperpolarisierung und Verfahren zur Herstellung eines Kontrastmittels
WO2025160283A1 (en) * 2024-01-24 2025-07-31 Vizma Life Sciences, Inc. Contrast agent device

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1276290A (en) * 1917-01-06 1918-08-20 Thomas Bailey Walker Process of and apparatus for hydrogenating fats, oils, waxes, and the like.
US2134571A (en) * 1934-07-27 1938-10-25 American Lurgi Corp Device for the hydrogenation of vegetable or animal oils or fats, fatty acids, or the like
US4194051A (en) * 1975-08-25 1980-03-18 Monsanto Company Asymmetric catalysis
JPH0721149B2 (ja) * 1989-12-04 1995-03-08 ユーオーピー 芳香族炭化水素の連続接触的選択的製造方法
ATE130292T1 (de) * 1993-09-22 1995-12-15 Pfizer Res & Dev Hydrierung.
IT1283650B1 (it) * 1996-08-02 1998-04-23 Bracco Spa Chelati paramagnetici ad alta relassivita' in siero
EP0951650B1 (de) * 1997-01-08 2003-12-10 Amersham Health AS Verfahren zur bilderzeugung mit magnetischer resonanz
DE19742548C2 (de) * 1997-09-26 1999-10-07 Otten Ernst Wilhelm Magneteinrichtung für Tansport und Aufbewahrung kernspinpolarisierter Gase und Verfahren zur Entnahme dieser Gase
KR100600670B1 (ko) * 1997-11-12 2006-07-13 지이 헬스케어 에이에스 파라수소 표지된 작용물질 및 자기공명영상에서의 그의 용도
US7501236B1 (en) * 1998-12-30 2009-03-10 Ge Healthcare Limited NMR spectroscopic in vitro assay using hyperpolarization

Also Published As

Publication number Publication date
KR100786476B1 (ko) 2007-12-17
JP2003500369A (ja) 2003-01-07
CA2372572C (en) 2008-12-02
US6872380B2 (en) 2005-03-29
WO2000071166A2 (en) 2000-11-30
EP1548454A1 (de) 2005-06-29
CN1357111A (zh) 2002-07-03
WO2000071166A3 (en) 2001-09-07
EP1179189A2 (de) 2002-02-13
US7459144B2 (en) 2008-12-02
CA2372572A1 (en) 2000-11-30
US20050152840A1 (en) 2005-07-14
AU775374B2 (en) 2004-07-29
GB9911681D0 (en) 1999-07-21
KR20020002463A (ko) 2002-01-09
CN1203321C (zh) 2005-05-25
DE60018408D1 (de) 2005-04-07
DE60018408T2 (de) 2005-12-29
EP1179189B1 (de) 2005-03-02
AU4772300A (en) 2000-12-12
US20020137965A1 (en) 2002-09-26
RU2240828C2 (ru) 2004-11-27

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