ATE290221T1 - Verfahren zur herstellung eines mr- kontrastmittels - Google Patents

Verfahren zur herstellung eines mr- kontrastmittels

Info

Publication number
ATE290221T1
ATE290221T1 AT00929722T AT00929722T ATE290221T1 AT E290221 T1 ATE290221 T1 AT E290221T1 AT 00929722 T AT00929722 T AT 00929722T AT 00929722 T AT00929722 T AT 00929722T AT E290221 T1 ATE290221 T1 AT E290221T1
Authority
AT
Austria
Prior art keywords
chamber
hydrogenation
inlet
liquid
solvent removal
Prior art date
Application number
AT00929722T
Other languages
English (en)
Inventor
Oskar Axelsson
Charlotte Olofsson
Axel Morgenstjerne
Georg Hansson
Haukur Johannesson
Jan H Ardenkjaer-Larsen
Original Assignee
Amersham Health As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10853772&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE290221(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amersham Health As filed Critical Amersham Health As
Application granted granted Critical
Publication of ATE290221T1 publication Critical patent/ATE290221T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
AT00929722T 1999-05-19 2000-05-17 Verfahren zur herstellung eines mr- kontrastmittels ATE290221T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9911681.6A GB9911681D0 (en) 1999-05-19 1999-05-19 Process
PCT/GB2000/001897 WO2000071166A2 (en) 1999-05-19 2000-05-17 Process

Publications (1)

Publication Number Publication Date
ATE290221T1 true ATE290221T1 (de) 2005-03-15

Family

ID=10853772

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00929722T ATE290221T1 (de) 1999-05-19 2000-05-17 Verfahren zur herstellung eines mr- kontrastmittels

Country Status (12)

Country Link
US (2) US6872380B2 (de)
EP (2) EP1548454A1 (de)
JP (1) JP2003500369A (de)
KR (1) KR100786476B1 (de)
CN (1) CN1203321C (de)
AT (1) ATE290221T1 (de)
AU (1) AU775374B2 (de)
CA (1) CA2372572C (de)
DE (1) DE60018408T2 (de)
GB (1) GB9911681D0 (de)
RU (1) RU2240828C2 (de)
WO (1) WO2000071166A2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9911679D0 (en) * 1999-05-19 1999-07-21 Nycomed Imaging As Magnetic resonance imaging
US6574496B1 (en) * 1999-05-19 2003-06-03 Amersham Health As Magnetic resonance imaging
GB0219953D0 (en) * 2002-08-29 2002-10-02 Amersham Health R & D Ab An arrangement and a method for providing contrast agents
GB0219952D0 (en) * 2002-08-29 2002-10-02 Amersham Health R & D Ab Method and apparatus for producing contrast agents for magnetic resonance imaging
GB0219954D0 (en) * 2002-08-29 2002-10-02 Amersham Health R & D Ab Method and apparatus for producing contrast agents for magnetic resonance imaging
ES2654520T3 (es) * 2005-10-11 2018-02-14 Huntington Medical Research Institutes Agentes de formación de imágenes y métodos de uso de los mismos
KR101321862B1 (ko) 2006-02-21 2013-10-28 밀리켈빈 테크놀로지스 엘엘씨 과분극화 방법, 시스템 및 조성물
EP2117607A4 (de) 2007-01-11 2012-08-08 Huntington Medical Res Inst Abbildungswirkstoffe und verfahren zu ihrer verwendung
US20080275668A1 (en) * 2007-05-02 2008-11-06 General Electric Company Apparatus and method for fully automated closed system optical measurement of volume
GB2450316A (en) * 2007-06-18 2008-12-24 Univ York Hyperpolarizing nuclei
WO2009046457A2 (en) * 2007-10-05 2009-04-09 Huntington Medical Research Institutes Imaging of genetic material with magnetic resonance
WO2009129265A1 (en) * 2008-04-14 2009-10-22 Huntington Medical Research Institutes Methods and apparatus for pasadena hyperpolarization
DK2349350T3 (en) 2008-10-03 2017-02-27 Bracco Imaging Spa PROCEDURE FOR PREPARING Aqueous SOLUTIONS OF HYPERPOLARIZED MOLECULES
US20110274626A1 (en) 2008-12-10 2011-11-10 University Of York Pulse sequencing with hyperpolarisable nuclei
EP2495333A1 (de) * 2011-03-03 2012-09-05 Roche Diagnostics GmbH Verfahren zum Herstellen eines Testelements zur Untersuchung einer Körperflüssigkeitsprobe und Testelement
WO2013167587A1 (en) 2012-05-07 2013-11-14 Albeda Innovation Aps Intra-operative cancer diagnosis based on a hyperpolarized marker
US9329246B2 (en) * 2012-10-03 2016-05-03 Bruker Biospin Ag Method for hyperpolarization transfer in the liquid state
US9566354B2 (en) 2012-10-23 2017-02-14 Vanderbilt University Systems and methods of performing NMR spectroscopy and MRI
CN103432977B (zh) * 2013-08-29 2015-01-07 中国科学院武汉物理与数学研究所 一种用于磁共振造影剂预极化的级联容器及其方法
CN105683144B (zh) 2013-10-28 2019-06-04 伯拉考成像股份公司 用于制备超极化羧化物化合物的方法
WO2017009856A1 (en) * 2015-07-16 2017-01-19 Aspect Imaging Ltd. Method and system for hyperpolarization of materials used in magnetic resonance imaging
WO2022266662A1 (en) * 2021-06-17 2022-12-22 University Of Florida Research Foundation, Inc. Methods and systems for producing hyperpolarized fluid samples
EP4141464A1 (de) * 2021-08-26 2023-03-01 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Breitbandverfahren zur signalverstärkung von magnetresonanzkontrastmitteln innerhalb von sekunden und deren reinigung
CA3246953A1 (en) * 2022-04-07 2023-10-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services PERFUSION DEVICE FOR THE PREPARATION AND ADMINISTRATION OF MRI PROBES
DE102023133847A1 (de) * 2023-12-04 2025-06-05 Albert-Ludwigs-Universität Freiburg, Körperschaft des öffentlichen Rechts Hyperpolarisator, Hyperpolarisationsanordnung, Verfahren zur Hyperpolarisierung und Verfahren zur Herstellung eines Kontrastmittels
WO2025160283A1 (en) * 2024-01-24 2025-07-31 Vizma Life Sciences, Inc. Contrast agent device

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1276290A (en) * 1917-01-06 1918-08-20 Thomas Bailey Walker Process of and apparatus for hydrogenating fats, oils, waxes, and the like.
US2134571A (en) * 1934-07-27 1938-10-25 American Lurgi Corp Device for the hydrogenation of vegetable or animal oils or fats, fatty acids, or the like
US4194051A (en) * 1975-08-25 1980-03-18 Monsanto Company Asymmetric catalysis
JPH0721149B2 (ja) * 1989-12-04 1995-03-08 ユーオーピー 芳香族炭化水素の連続接触的選択的製造方法
DK0644176T3 (da) * 1993-09-22 1996-02-26 Pfizer Ltd Hydrogenering
IT1283650B1 (it) * 1996-08-02 1998-04-23 Bracco Spa Chelati paramagnetici ad alta relassivita' in siero
EP0951650B1 (de) * 1997-01-08 2003-12-10 Amersham Health AS Verfahren zur bilderzeugung mit magnetischer resonanz
DE19742548C2 (de) * 1997-09-26 1999-10-07 Otten Ernst Wilhelm Magneteinrichtung für Tansport und Aufbewahrung kernspinpolarisierter Gase und Verfahren zur Entnahme dieser Gase
AU1047399A (en) * 1997-11-12 1999-05-31 Nycomed Imaging As Para-hydrogen labelled agents and their use in magnetic resonance imaging
IL143927A0 (en) * 1998-12-30 2002-04-21 Nycomed Amersham Plc Nmr spectroscopic in vitro assay using hyperpolarization

Also Published As

Publication number Publication date
EP1179189A2 (de) 2002-02-13
JP2003500369A (ja) 2003-01-07
EP1179189B1 (de) 2005-03-02
US20020137965A1 (en) 2002-09-26
RU2240828C2 (ru) 2004-11-27
WO2000071166A3 (en) 2001-09-07
AU775374B2 (en) 2004-07-29
AU4772300A (en) 2000-12-12
US7459144B2 (en) 2008-12-02
US6872380B2 (en) 2005-03-29
WO2000071166A2 (en) 2000-11-30
CA2372572C (en) 2008-12-02
DE60018408D1 (de) 2005-04-07
CN1203321C (zh) 2005-05-25
CN1357111A (zh) 2002-07-03
KR100786476B1 (ko) 2007-12-17
DE60018408T2 (de) 2005-12-29
CA2372572A1 (en) 2000-11-30
US20050152840A1 (en) 2005-07-14
GB9911681D0 (en) 1999-07-21
KR20020002463A (ko) 2002-01-09
EP1548454A1 (de) 2005-06-29

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