ATE290605T1 - Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen - Google Patents

Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen

Info

Publication number
ATE290605T1
ATE290605T1 AT99930490T AT99930490T ATE290605T1 AT E290605 T1 ATE290605 T1 AT E290605T1 AT 99930490 T AT99930490 T AT 99930490T AT 99930490 T AT99930490 T AT 99930490T AT E290605 T1 ATE290605 T1 AT E290605T1
Authority
AT
Austria
Prior art keywords
reverse transcriptase
dna
drug
assay
amplified
Prior art date
Application number
AT99930490T
Other languages
English (en)
Inventor
Walid M Heneine
Gerardo Garcia Lerma
Shinji Yamamoto
William M Switzer
Thomas M Folks
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE290605T1 publication Critical patent/ATE290605T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
AT99930490T 1998-06-19 1999-06-18 Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen ATE290605T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9005198P 1998-06-19 1998-06-19
PCT/US1999/013957 WO1999066068A2 (en) 1998-06-19 1999-06-18 Method and kit for detecting resistance to antiviral drugs

Publications (1)

Publication Number Publication Date
ATE290605T1 true ATE290605T1 (de) 2005-03-15

Family

ID=22221041

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99930490T ATE290605T1 (de) 1998-06-19 1999-06-18 Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen

Country Status (6)

Country Link
EP (1) EP1100959B1 (de)
AT (1) ATE290605T1 (de)
CA (1) CA2331260C (de)
DE (1) DE69924118T2 (de)
ES (1) ES2237923T3 (de)
WO (1) WO1999066068A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1160332A1 (de) * 2000-05-30 2001-12-05 Amsterdam Support Diagnostics B.V. Verfahren zum Nachweis von enzymatischer Aktivität oder von Resistenz gegen enzymatiche Inhibitoren
WO2001098541A2 (en) * 2000-06-21 2001-12-27 Harris Robert B Measuring viral reverse transcriptase activity
BR112019027993A2 (pt) * 2017-07-04 2020-07-07 Cavidi Ab métodos para avaliar a susceptibilidade de um vírus ao tratamento com um fármaco inibidor de uma enzima do vírus do tipo selvagem, para avaliar se um paciente tratado para uma infecção viral tem necessidade de alterar a terapia farmacológica com um fármaco inibidor da enzima viral e para determinar a carga de um vírus em uma amostra do paciente e a dita resistência do vírus ao tratamento com um fármaco inibidor de uma enzima do vírus do tipo selvagem, e, sistema
CN116732242A (zh) * 2023-03-16 2023-09-12 赛立安生物技术(广州)有限公司 一种用于检测hiv-1蛋白酶区和逆转录酶区耐药突变的引物组、试剂盒及其检测方法
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4248593A (en) * 1992-05-14 1993-12-13 Mark Holodniy Polymerase chain reaction assays for monitoring antiviral therapy
DE69604051T2 (de) * 1995-01-27 1999-12-16 The Government Of The United States Of America, As Represented By The Secretary Verfahren zum sensitiven nachweis von reverser transcriptase
EP0852626B1 (de) * 1996-01-29 2002-04-03 Virologic, Inc. Verfahren und zusammensetzungen zur bestimmung der empfindlichkeit und resistenz gegen antivirale wirkstoffe und screening für antivirale wirkstoffe

Also Published As

Publication number Publication date
WO1999066068A3 (en) 2001-03-29
DE69924118T2 (de) 2005-12-22
CA2331260A1 (en) 1999-12-23
DE69924118D1 (de) 2005-04-14
CA2331260C (en) 2008-03-18
EP1100959B1 (de) 2005-03-09
ES2237923T3 (es) 2005-08-01
WO1999066068A2 (en) 1999-12-23
EP1100959A2 (de) 2001-05-23

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