ATE290868T1 - Verwendung von 19-nor-vitamin-d-verbindungen zur vorbeugung von hyperphosphatemie bei nierenkrankheiten - Google Patents

Verwendung von 19-nor-vitamin-d-verbindungen zur vorbeugung von hyperphosphatemie bei nierenkrankheiten

Info

Publication number: ATE290868T1
Authority: AT; Austria
Prior art keywords: vitamin; compounds; kidney disease; analogs; pth
Prior art date: 1995-07-13

Application number

AT96926066T

Other languages

English (en)

Inventor

Hector F Deluca

Eduardo Slatopolsky

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-13

Filing date

1996-07-09

Publication date

2005-04-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23997158&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE290868(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-07-09 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

2005-04-15 Application granted granted Critical

2005-04-15 Publication of ATE290868T1 publication Critical patent/ATE290868T1/de

Links

PKFBWEUIKKCWEW-WEZTXPJVSA-N (1r,3r)-5-[(2e)-2-[(1r,3as,7ar)-1-[(2r)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1C[C@@H](O)C[C@H](O)C1 PKFBWEUIKKCWEW-WEZTXPJVSA-N 0.000 title abstract 2
208000017169 kidney disease Diseases 0.000 title abstract 2
201000005991 hyperphosphatemia Diseases 0.000 title 1
102000003982 Parathyroid hormone Human genes 0.000 abstract 3
108090000445 Parathyroid hormone Proteins 0.000 abstract 3
239000000199 parathyroid hormone Substances 0.000 abstract 3
229960001319 parathyroid hormone Drugs 0.000 abstract 3
210000002966 serum Anatomy 0.000 abstract 2
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
208000005770 Secondary Hyperparathyroidism Diseases 0.000 abstract 1
230000000125 calcaemic effect Effects 0.000 abstract 1
239000011575 calcium Substances 0.000 abstract 1
229910052791 calcium Inorganic materials 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
201000006370 kidney failure Diseases 0.000 abstract 1
BPKAHTKRCLCHEA-UBFJEZKGSA-N paricalcitol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](\C=C\[C@H](C)C(C)(C)O)C)=C\C=C1C[C@@H](O)C[C@H](O)C1 BPKAHTKRCLCHEA-UBFJEZKGSA-N 0.000 abstract 1
230000003173 phosphatemic effect Effects 0.000 abstract 1
239000011574 phosphorus Substances 0.000 abstract 1
229910052698 phosphorus Inorganic materials 0.000 abstract 1
230000028327 secretion Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Obesity (AREA)
Nutrition Science (AREA)
Rheumatology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT96926066T 1995-07-13 1996-07-09 Verwendung von 19-nor-vitamin-d-verbindungen zur vorbeugung von hyperphosphatemie bei nierenkrankheiten ATE290868T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/502,288 US5597815A (en)	1995-07-13	1995-07-13	Prevention of hyperphosphatemia in kidney disorder patients
PCT/US1996/011486 WO1997002826A2 (en)	1995-07-13	1996-07-09	Use of 19-nor-vitamin d compounds for the prevention of hyperphosphatemia in kidney disorder patients

Publications (1)

Publication Number	Publication Date
ATE290868T1 true ATE290868T1 (de)	2005-04-15

Family

ID=23997158

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96926066T ATE290868T1 (de)	1995-07-13	1996-07-09	Verwendung von 19-nor-vitamin-d-verbindungen zur vorbeugung von hyperphosphatemie bei nierenkrankheiten

Country Status (12)

Country	Link
US (1)	US5597815A (de)
EP (1)	EP0837681B1 (de)
JP (1)	JP3255926B2 (de)
AT (1)	ATE290868T1 (de)
AU (1)	AU705895B2 (de)
CA (1)	CA2224284C (de)
DE (1)	DE69634483T2 (de)
DK (1)	DK0837681T3 (de)
ES (1)	ES2236742T3 (de)
NZ (1)	NZ313816A (de)
PT (1)	PT837681E (de)
WO (1)	WO1997002826A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2002510304A (ja) *	1997-06-06	2002-04-02	ウイスコンシンアラムナイリサーチフオンデーシヨン	移植体拒絶反応を防ぐためのビタミンｄ化合物の使用
US5939406A (en) *	1997-07-21	1999-08-17	Wisconsin Alumni Research Foundation	18-substituted-19-nor-vitamin D compounds
US6359152B2 (en)	1997-07-21	2002-03-19	Wisconsin Alumni Research Foundation	18-substituted-19-nor-vitamin D compounds
US6136799A (en) *	1998-04-08	2000-10-24	Abbott Laboratories	Cosolvent formulations
DE69913092T2 (de) *	1999-01-27	2004-09-09	Commissariat à l'Energie Atomique	Microassay zur Serienanalyse der Genexpression und Anwendungen davon
CA2420759A1 (en) *	2000-08-30	2003-02-27	Daishiro Miura	Parathyroid hormone production inhibitors containing vitamin d3 derivatives
US7129230B2 (en)	2001-03-12	2006-10-31	Nestec S.A.	Method and product for treating cancer in pets
US6887897B2 (en)	2001-07-31	2005-05-03	Mission Pharmacal Company	Calcium glutarate supplement and phosphorus binder
WO2004062620A2 (en) *	2003-01-13	2004-07-29	Cedars-Sinai Medical Center	Paricalcitol as a chemotherapeutic agent
US20050148557A1 (en) *	2003-07-29	2005-07-07	Jin Tian	Use of Vitamin Ds to treat kidney disease
BRPI0716319A8 (pt) *	2006-10-25	2019-02-05	Aovatechnologies Inc	método para reduzir a absorção de fosfato em um indivíduo animal humano ou não-humano correndo o risco de desenvolver ou que desenvolveu hiperfosfatomia e método para reduzir os efeitos colaterais da terapia de vitamina d em um ser humano
WO2010083613A1 (en) *	2009-01-26	2010-07-29	Cytochroma Inc.	Phosphate management with small molecules

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ232734A (en) *	1989-03-09	1991-11-26	Wisconsin Alumni Res Found	19-nor vitamin d derivatives and pharmaceutical compositions
US5246925A (en) *	1989-03-09	1993-09-21	Wisconsin Alumni Research Foundation	19-nor-vitamin D compounds for use in treating hyperparathyroidism
CA1333616C (en) *	1989-03-09	1994-12-20	Hector F. Deluca	19-nor-vitamin d compounds
GB2229921B (en) *	1989-04-05	1992-12-16	Chugai Pharmaceutical Co Ltd	Treatment for hyperparathyroidism with use of vitamin d derivatives
AU650751B2 (en) *	1991-05-28	1994-06-30	Wisconsin Alumni Research Foundation	Novel synthesis of 19-nor vitamin D compounds
US5086191A (en) *	1991-05-28	1992-02-04	Wisconsin Alumni Research Foundation	Intermediates for the synthesis of 19-nor vitamin D compounds

1995
- 1995-07-13 US US08/502,288 patent/US5597815A/en not_active Expired - Lifetime
1996
- 1996-07-09 AT AT96926066T patent/ATE290868T1/de active
- 1996-07-09 DK DK96926066T patent/DK0837681T3/da active
- 1996-07-09 ES ES96926066T patent/ES2236742T3/es not_active Expired - Lifetime
- 1996-07-09 NZ NZ313816A patent/NZ313816A/en not_active IP Right Cessation
- 1996-07-09 PT PT96926066T patent/PT837681E/pt unknown
- 1996-07-09 AU AU66364/96A patent/AU705895B2/en not_active Expired
- 1996-07-09 WO PCT/US1996/011486 patent/WO1997002826A2/en not_active Ceased
- 1996-07-09 CA CA002224284A patent/CA2224284C/en not_active Expired - Lifetime
- 1996-07-09 DE DE69634483T patent/DE69634483T2/de not_active Expired - Lifetime
- 1996-07-09 EP EP96926066A patent/EP0837681B1/de not_active Expired - Lifetime
- 1996-07-09 JP JP50595697A patent/JP3255926B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU6636496A (en)	1997-02-10
ES2236742T3 (es)	2005-07-16
EP0837681B1 (de)	2005-03-16
MX9800342A (es)	1998-07-31
JP3255926B2 (ja)	2002-02-12
DK0837681T3 (da)	2005-06-13
CA2224284A1 (en)	1997-01-30
DE69634483T2 (de)	2006-04-13
CA2224284C (en)	2003-12-02
US5597815A (en)	1997-01-28
AU705895B2 (en)	1999-06-03
WO1997002826A2 (en)	1997-01-30
WO1997002826A3 (en)	1997-03-13
PT837681E (pt)	2005-06-30
JPH11502862A (ja)	1999-03-09
EP0837681A2 (de)	1998-04-29
NZ313816A (en)	2001-06-29
DE69634483D1 (de)	2005-04-21

Legal Events

Date

Code

Title

Description

2006-01-15

UEP

Publication of translation of european patent specification

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Publication	Publication Date	Title
DE69634483D1 (de)	2005-04-21	Verwendung von 19-nor-vitamin-d-verbindungen zur vorbeugung von hyperphosphatemie bei nierenkrankheiten
KAYE et al.	1970	Arrest of hyperparathyroid bone disease with dihydrotachysterol in patients undergoing chronic hemodialysis
IL139353A (en)	2005-08-31	1alpha-HYDROXY-25-ENE-VITAMIN D, ANALOGS AND USES THEREOF
BG105253A (en)	2001-12-29	Calcium (3s) tetrahydro-3-furanyl(1s,2r)-3-[[(4-aminophenyl)sulfonyl] (isobutyl) amino]-1-benzyl-2-(phosphonooxy)propylcarbamate
ATE61370T1 (de)	1991-03-15	Pharmazeutische zusammensetzungen, die geminale diphosphonate enthalten.
ES270607Y (es)	1984-03-01	Implante de huesos, especialmente protesis para la articulacion de la cadera.
WO2000043402A3 (en)	2000-11-30	Inhibitors of intestinal apical membrane na/phosphate co-transportation
AU7793887A (en)	1988-03-17	Therapeutic composition comprising gamma-linolenic acid and calcium
FR2491334B1 (de)	1983-09-23
EP2241329A3 (de)	2011-03-09	Anti-Interleukin-9 Antikörper oder Anti-Interleukin-9 Rezeptor Antikörper zur Behandlung von bronchialem Hyperreaktionsvermögen
ATE370941T1 (de)	2007-09-15	Modulatoren des vitamin-d-rezeptors
BR9808233A (pt)	2000-05-16	Preparação farmacêutica
PT97337A (pt)	1992-01-31	Metodo para o tratamento de doencas neoplasticas com conjugados do acido difluoroglutamico com folatos e anti-folatos
NO965228D0 (no)	1996-12-06	Pyridylbisfosfonater for anvendelse som terapeutisk middel
NZ222434A (en)	1990-06-26	Tissue factor protein lacking its naturally associated phospholipid
ES8507349A1 (es)	1985-09-01	Una pasta para hemostasis y union temporal de defectos en casos de traumas de huesos
ES2166800T3 (es)	2002-05-01	Procedimiento para la preparacion de o,s-acetales de 2,2-difluoroceteno sililo y o,s-esteres del acido alfa,alfa-difluoro-beta-sililoxi-1,3-dioxolan-4-propanoico.
WO2000010548A3 (en)	2001-11-29	19-nor-vitamin d3 compounds with calcemic activity
Lapatsanis et al.	1976	Two types of nutritional rickets in infants
DE3380923D1 (de)	1990-01-11	Pharmazeutische zusammensetzungen zur behandlung von stoerungen, bedingt durch humanendrogen.
EP0116628A4 (de)	1985-02-18	1-acyl-3-pyridylmethylguanidine und deren verwendung als antihypertensiva.
HUT46842A (en)	1988-12-28	Biocompatible layered body containing calcium phosphate and method for producing same
ATA33585A (de)	1995-01-15	Doppelstocktrogbeute für die zweivölkerbetriebsweise zur gänzlichen schwarmunterbindung
BR0307021A (pt)	2004-11-03	Uso de alquilfosfocolinas no tratamento preventivo de doenças de protozoários
Willvonseder et al.	1976	Immunoreactive Parathyroid Hormone and Calcitonin in Normocalcemic Hypercalciuria