ATE290902T1 - Vorrichtung zur iontophoretischen verabreichung von medikamenten mit internen sensoren - Google Patents

Vorrichtung zur iontophoretischen verabreichung von medikamenten mit internen sensoren

Info

Publication number
ATE290902T1
ATE290902T1 AT00922164T AT00922164T ATE290902T1 AT E290902 T1 ATE290902 T1 AT E290902T1 AT 00922164 T AT00922164 T AT 00922164T AT 00922164 T AT00922164 T AT 00922164T AT E290902 T1 ATE290902 T1 AT E290902T1
Authority
AT
Austria
Prior art keywords
reservoir
medication
internal sensors
housing
sensor
Prior art date
Application number
AT00922164T
Other languages
English (en)
Inventor
Ying Sun
Stephen J Wisniewski
Ralph W Oakeson
Jonas C T Wang
Original Assignee
Johnson & Johnson Consumer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson Consumer filed Critical Johnson & Johnson Consumer
Application granted granted Critical
Publication of ATE290902T1 publication Critical patent/ATE290902T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0412Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/0436Material of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pipeline Systems (AREA)
  • Control Of Conveyors (AREA)
AT00922164T 1999-04-16 2000-04-13 Vorrichtung zur iontophoretischen verabreichung von medikamenten mit internen sensoren ATE290902T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12980799P 1999-04-16 1999-04-16
PCT/US2000/009955 WO2000062857A1 (en) 1999-04-16 2000-04-13 Electrotransport delivery system comprising internal sensors

Publications (1)

Publication Number Publication Date
ATE290902T1 true ATE290902T1 (de) 2005-04-15

Family

ID=22441691

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00922164T ATE290902T1 (de) 1999-04-16 2000-04-13 Vorrichtung zur iontophoretischen verabreichung von medikamenten mit internen sensoren

Country Status (8)

Country Link
US (1) US6678554B1 (de)
EP (1) EP1171195B1 (de)
JP (1) JP4180244B2 (de)
AT (1) ATE290902T1 (de)
AU (1) AU4239300A (de)
CA (1) CA2370349C (de)
DE (1) DE60018726T2 (de)
WO (1) WO2000062857A1 (de)

Families Citing this family (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4414517B2 (ja) * 1999-09-01 2010-02-10 久光製薬株式会社 イオントフォレーシス用デバイス構造体
US7404815B2 (en) * 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US20020115960A1 (en) * 2000-08-24 2002-08-22 Redding Bruce K. Substance delivery system
US6908448B2 (en) * 2001-08-24 2005-06-21 Dermisonics, Inc. Substance delivery device
EP1469903A2 (de) * 2001-09-28 2004-10-27 BioValve Technologies, Inc. Mikronadel mit membran
DE10205373B4 (de) * 2002-02-09 2007-07-19 Aloys Wobben Brandschutz
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
US20070020321A1 (en) * 2003-01-16 2007-01-25 Redding Bruce K Method for enhancing attenuation characteristic of absorbent materials useful with dermal and transdermal substance delivery systems
US6872292B2 (en) * 2003-01-28 2005-03-29 Microlin, L.C. Voltage modulation of advanced electrochemical delivery system
CN1774239A (zh) * 2003-01-29 2006-05-17 埃-皮尔制药公司 用于胃肠道的有效药物递送
US20050058701A1 (en) * 2003-01-29 2005-03-17 Yossi Gross Active drug delivery in the gastrointestinal tract
US20040267240A1 (en) * 2003-01-29 2004-12-30 Yossi Gross Active drug delivery in the gastrointestinal tract
US7476222B2 (en) 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of reducing the appearance of pigmentation with galvanic generated electricity
US7479133B2 (en) 2003-06-30 2009-01-20 Johnson & Johnson Consumer Companies, Inc. Methods of treating acne and rosacea with galvanic generated electricity
US8734421B2 (en) 2003-06-30 2014-05-27 Johnson & Johnson Consumer Companies, Inc. Methods of treating pores on the skin with electricity
US7507228B2 (en) 2003-06-30 2009-03-24 Johnson & Johnson Consumer Companies, Inc. Device containing a light emitting diode for treatment of barrier membranes
US7486989B2 (en) 2003-06-30 2009-02-03 Johnson & Johnson Consumer Companies, Inc. Device for delivery of oxidizing agents to barrier membranes
US7477941B2 (en) 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of exfoliating the skin with electricity
US7477939B2 (en) 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of treating a wound with galvanic generated electricity
US7480530B2 (en) 2003-06-30 2009-01-20 Johnson & Johnson Consumer Companies, Inc. Device for treatment of barrier membranes
US7477938B2 (en) 2003-06-30 2009-01-13 Johnson & Johnson Cosumer Companies, Inc. Device for delivery of active agents to barrier membranes
US7477940B2 (en) 2003-06-30 2009-01-13 J&J Consumer Companies, Inc. Methods of administering an active agent to a human barrier membrane with galvanic generated electricity
WO2005004980A1 (en) * 2003-07-14 2005-01-20 Power Paper Ltd. Method, apparatus, and kit for onychomycosis treatment using electrokinetic transport of substances
CN1636505B (zh) * 2004-01-09 2011-11-09 希森美康株式会社 提取器具、提取装置和血糖值测量装置
WO2005084257A2 (en) * 2004-02-26 2005-09-15 Vpn Solutions, Llc Composite thin-film glucose sensor
CA2572870A1 (en) * 2004-07-06 2006-01-12 Transpharma Medical Ltd. Delivery system for transdermal immunization
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
US20060135906A1 (en) * 2004-11-16 2006-06-22 Akihiko Matsumura Iontophoretic device and method for administering immune response-enhancing agents and compositions
JP4728631B2 (ja) * 2004-11-30 2011-07-20 Tti・エルビュー株式会社 イオントフォレーシス装置
US7590444B2 (en) * 2004-12-09 2009-09-15 Tti Ellebeau, Inc. Iontophoresis device
US20060263257A1 (en) * 2004-12-13 2006-11-23 Beauchamp Jesse L Optical gas sensor based on dyed high surface area substrates
WO2006072887A1 (en) * 2005-01-05 2006-07-13 Eyegate Pharma Sa Ocular iontophoresis device for delivering sirna and aptamers
JP4731931B2 (ja) * 2005-02-03 2011-07-27 Tti・エルビュー株式会社 イオントフォレーシス装置
JP4793806B2 (ja) * 2005-03-22 2011-10-12 Tti・エルビュー株式会社 イオントフォレーシス装置
JP2006296511A (ja) * 2005-04-15 2006-11-02 Transcutaneous Technologies Inc 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ
US7856263B2 (en) 2005-04-22 2010-12-21 Travanti Pharma Inc. Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis
US20060258973A1 (en) * 2005-04-27 2006-11-16 Kevin Volt Micro-current Iontophoretic Percutaneous Absorptive Patch
JP2008540023A (ja) * 2005-05-19 2008-11-20 イー−ピル ファーマ リミティド 組織における一酸化窒素生成のための摂取可能デバイス
US20060265031A1 (en) * 2005-05-20 2006-11-23 Medtronic, Inc. Operation indicator for a portable therapy delivery device
JP2006334164A (ja) * 2005-06-02 2006-12-14 Transcutaneous Technologies Inc イオントフォレーシス装置及びその制御方法
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
JP2007000342A (ja) * 2005-06-23 2007-01-11 Transcutaneous Technologies Inc 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置
US20070027426A1 (en) * 2005-06-24 2007-02-01 Transcutaneous Technologies Inc. Iontophoresis device to deliver active agents to biological interfaces
JPWO2007010900A1 (ja) * 2005-07-15 2009-01-29 Tti・エルビュー株式会社 貼付位置表示機能付き経皮吸収用パッチ及びイオントフォレーシス装置
WO2007018589A2 (en) * 2005-07-28 2007-02-15 Bio-Rad Laboratories, Inc. Separation of proteins based on isoelectric point using solid-phase buffers
JP2007037868A (ja) * 2005-08-05 2007-02-15 Transcutaneous Technologies Inc 経皮投与装置及びその制御方法
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US20070088331A1 (en) * 2005-08-18 2007-04-19 Transcutaneous Technologies Inc. Method and apparatus for managing active agent usage, and active agent injecting device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
US20090254018A1 (en) * 2005-08-24 2009-10-08 Mizuo Nakayama Electrode assembly for freezing-type iontophoresis device
WO2007026672A1 (ja) * 2005-08-29 2007-03-08 Transcu Ltd. イオントフォレーシス用汎用性電解液組成物
WO2007029611A1 (ja) * 2005-09-06 2007-03-15 Tti Ellebeau, Inc. イオントフォレーシス装置
US20070112294A1 (en) * 2005-09-14 2007-05-17 Transcutaneous Technologies Inc. Iontophoresis device
KR20080047600A (ko) * 2005-09-15 2008-05-29 티티아이 엘뷰 가부시키가이샤 로드형 이온토포레시스 장치
KR20080056200A (ko) * 2005-09-16 2008-06-20 티티아이 엘뷰 가부시키가이샤 카테터형 이온토포레시스 장치
US20070066934A1 (en) * 2005-09-19 2007-03-22 Transport Pharmaceuticals, Inc. Electrokinetic delivery system and methods therefor
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate
US20070073212A1 (en) * 2005-09-28 2007-03-29 Takehiko Matsumura Iontophoresis apparatus and method to deliver active agents to biological interfaces
JPWO2007037324A1 (ja) * 2005-09-28 2009-04-09 Tti・エルビュー株式会社 乾燥型イオントフォレーシス用電極構造体
US20090299265A1 (en) * 2005-09-30 2009-12-03 Tti Ellebeau, Inc. Electrode Assembly for Iontophoresis Having Shape-Memory Separator and Iontophoresis Device Using the Same
EP1944057A4 (de) * 2005-09-30 2009-02-18 Tti Ellebeau Inc Iontophorese-gerät zur kontrolle der dosis und zeit der verabreichung eines schlafinduzierenden und analeptischen mittels
JP2009509659A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
US20070078376A1 (en) * 2005-09-30 2007-04-05 Smith Gregory A Functionalized microneedles transdermal drug delivery systems, devices, and methods
AU2006299520A1 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Iontophoresis device to deliver multiple active agents to biological interfaces
WO2007041386A2 (en) * 2005-09-30 2007-04-12 Vyteris, Inc. Pulsatile delivery of gonadotropin-releasing hormone from a pre-loaded integrated electrotransport patch
US20070135754A1 (en) * 2005-09-30 2007-06-14 Hidero Akiyama Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same
KR20080080087A (ko) * 2005-09-30 2008-09-02 티티아이 엘뷰 가부시키가이샤 신규 약학 담체를 이용한 경피 약물 전달시스템, 장치 및방법
JP2009509677A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 小胞封入活性物質のイオントフォレーシス送達
US20070078445A1 (en) * 2005-09-30 2007-04-05 Curt Malloy Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces
US20070232983A1 (en) * 2005-09-30 2007-10-04 Smith Gregory A Handheld apparatus to deliver active agents to biological interfaces
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
US8550743B2 (en) 2005-09-30 2013-10-08 Medtronic, Inc. Sliding lock device
WO2007041118A1 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Iontophoretic device and method of delivery of active agents to biological interface
EP1928542A1 (de) * 2005-09-30 2008-06-11 Tti Ellebeau, Inc. Verfahren und system zum nachweis von fehlfunktionen in einer iontophorese-vorrichtung, die wirkstoffe an biologische schnittstellen abgibt
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
US8099162B2 (en) 2005-11-29 2012-01-17 Eyegate Pharma, S.A.S. Ocular iontophoresis device
FR2893852B1 (fr) * 2005-11-29 2010-09-03 Eyegate Pharma Sa Dispositif d'iontophorese oculaire
US20080033338A1 (en) * 2005-12-28 2008-02-07 Smith Gregory A Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
US20080033398A1 (en) * 2005-12-29 2008-02-07 Transcutaneous Technologies Inc. Device and method for enhancing immune response by electrical stimulation
EP1965858A2 (de) * 2005-12-30 2008-09-10 Tti Ellebeau, Inc. System und verfahren zur fernsteuerung eines iontophoresegerätes
WO2007079193A2 (en) * 2005-12-30 2007-07-12 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
US20080004564A1 (en) * 2006-03-30 2008-01-03 Transcutaneous Technologies Inc. Controlled release membrane and methods of use
JP2009542685A (ja) * 2006-07-05 2009-12-03 Tti・エルビュー株式会社 自己組織性樹脂状高分子を有する送達装置及びその使用方法
US20080077076A1 (en) * 2006-08-29 2008-03-27 Transcutaneous Technologies Inc. Iontophoresis device and method for operation with a usb (universal serial bus) power source
CN101528300A (zh) * 2006-09-05 2009-09-09 Tti优而美株式会社 使用感应电源的透皮药物输送系统、装置和方法
US8048069B2 (en) * 2006-09-29 2011-11-01 Medtronic, Inc. User interface for ablation therapy
US20080193514A1 (en) * 2006-11-02 2008-08-14 Transcu Ltd. Compostions and methods for iontophoresis delivery of active ingredients through hair follicles
KR20090106492A (ko) 2006-12-01 2009-10-09 티티아이 엘뷰 가부시키가이샤 경피성 전달 장치와 같은 장치에 전력을 제공하거나 제어하기 위한 시스템, 장치, 및 방법
WO2008131072A1 (en) * 2007-04-17 2008-10-30 Transport Pharmaceuticals, Inc. Current density detection and control system and method for an electrokinetic delivery of medicaments
US8945114B2 (en) * 2007-04-26 2015-02-03 Medtronic, Inc. Fluid sensor for ablation therapy
AU2008254748A1 (en) * 2007-05-18 2008-11-27 Tti Ellebeau, Inc. Transdermal delivery devices assuring an improved release of an active principle through a biological interface
US9037229B2 (en) * 2007-10-09 2015-05-19 Syneron Medical Ltd Magnetic patch coupling
WO2009057173A1 (en) * 2007-11-02 2009-05-07 M & T S.R.L. Device for localized transfer of a filler
KR101287351B1 (ko) 2007-12-05 2013-07-23 시네론 메디컬 리미티드 피부 치료장치용 캐리어
WO2009090632A2 (en) 2008-01-17 2009-07-23 Syneron Medical Ltd. A hair removal apparatus for personal use and the method of using same
MX2010007407A (es) * 2008-01-24 2010-08-16 Syneron Medical Ltd Dispositivo, aparato, y metodo para tratamiento de tejido adiposo.
JP2011522616A (ja) * 2008-06-04 2011-08-04 セブンス センス バイオシステムズ,インコーポレーテッド シングルステップ診断のための組成物および方法
US8150525B2 (en) 2008-08-27 2012-04-03 Johnson & Johnson Consumer Companies, Inc. Treatment of hyperhydrosis
US20100069877A1 (en) * 2008-09-10 2010-03-18 Smith Gregory A Apparatus and method to dispense hpc-based viscous liquids into porous substrates, e.g., continuous web-based process
WO2010032235A1 (en) * 2008-09-21 2010-03-25 Syneron Medical Ltd. A method and apparatus for personal skin treatment
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
US9041541B2 (en) * 2010-01-28 2015-05-26 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
WO2010101626A1 (en) 2009-03-02 2010-09-10 Seventh Sense Biosystems, Inc. Techniques and devices associated with blood sampling
US20100286587A1 (en) * 2009-05-07 2010-11-11 Yossi Gross Sublingual electrical drug delivery
US20100286628A1 (en) * 2009-05-07 2010-11-11 Rainbow Medical Ltd Gastric anchor
US8414559B2 (en) * 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
US20110066175A1 (en) * 2009-05-07 2011-03-17 Rainbow Medical Ltd. Gastric anchor
CA2760467A1 (en) * 2009-05-08 2010-11-11 Isis Biopolymer, Inc. Iontophoretic device with improved counterelectrode
TW201121604A (en) * 2009-06-09 2011-07-01 Tti Ellebeau Inc Long life high capacity electrode, device, and method of manufacture
WO2011053787A2 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Systems and methods for application to skin and control of actuation, delivery and/or perception thereof
US8744567B2 (en) 2009-11-13 2014-06-03 Johnson & Johnson Consumer Companies, Inc. Galvanic skin treatment device
WO2011065972A2 (en) * 2009-11-24 2011-06-03 Seventh Sense Biosystems, Inc. Patient-enacted sampling technique
CN102811754B (zh) * 2010-01-13 2017-05-17 第七感生物系统有限公司 流体的快速输送和/或抽出
CN102791197B (zh) * 2010-01-13 2016-03-23 第七感生物系统有限公司 取样装置接口
DE102010021975B4 (de) * 2010-05-28 2020-01-16 Dräger Safety AG & Co. KGaA Elektrochemischer Gassensor und Verwendung eines elektrochemischen Gassensors zum Nachweis von Blausäure
US20120016308A1 (en) 2010-07-16 2012-01-19 Seventh Sense Biosystems, Inc. Low-pressure packaging for fluid devices
USD678534S1 (en) 2010-07-20 2013-03-19 Iontera, Inc. Iontophoretic device for application to the brow/forehead of a person
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
WO2012064802A1 (en) 2010-11-09 2012-05-18 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
EP3236259A1 (de) 2011-04-29 2017-10-25 Seventh Sense Biosystems, Inc. Plasma- oder serumherstellung und entfernung von flüssigkeiten bei reduziertem druck
ITTO20110374A1 (it) * 2011-04-29 2012-10-30 Igea S P A Metodo di controllo di un dispositivo di elettro-porazione
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
JP6121400B2 (ja) 2011-04-29 2017-04-26 セブンス センス バイオシステムズ,インコーポレーテッド 流体の送達および/または受け取り
BR112014008952B1 (pt) * 2011-10-28 2020-06-02 Koninklijke Philips N.V. Sensor para medição de uma concentração de gás solúvel em fluido, e, sistema para o monitoramento e/ou a ventilação do paciente de um paciente
RU2686427C2 (ru) * 2011-12-08 2019-04-25 Пилоджикс Л.П. Устройство и способ для стимуляции роста волос и/или предотвращения выпадения волос
US11110272B2 (en) * 2011-12-08 2021-09-07 Pilogics L.P. Apparatus for stimulating hair growth and/or preventing hair loss
WO2013190537A1 (en) * 2012-06-18 2013-12-27 Michael Tavger Method and system for delivering solution into the pores of recipient human skin
US9744353B2 (en) * 2012-11-14 2017-08-29 Teva Pharmaceuticals International Gmbh Detection of presence and alignment of a therapeutic agent in an iontophoretic drug delivery device
MX2017009193A (es) 2015-01-22 2017-12-12 Eyegate Pharmaceuticals Inc Lente de contacto iontoforetica.
CN107405483A (zh) * 2015-03-09 2017-11-28 皇家飞利浦有限公司 离子电渗的设备、装置和方法
WO2017119519A1 (ko) * 2016-01-05 2017-07-13 바이오센서연구소 주식회사 약물 전달을 위한 이온토포레시스 장치 및 그를 제조하는 방법
US9901735B1 (en) * 2016-08-04 2018-02-27 Y-Brain Inc Ancillary device for electrical stimulation device and electrical stimulation device
EP3421080B1 (de) * 2017-06-28 2021-05-05 Fundación Tecnalia Research & Innovation Vorrichtung zur kontrollierten und überwachten transdermalen wirkstofffreisetzung und verwendung davon
BR112020002359A2 (pt) * 2017-08-04 2020-09-01 Solenis Technologies Cayman, L.P. método para determinar a concentração de inibidor de depósito em água salgada com um eletrodo de íon seletivo de cálcio/magnésio
US12527950B2 (en) * 2018-07-09 2026-01-20 NanoCav, LLC Electroporation devices and methods of cell transfection

Family Cites Families (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1017883B (de) 1954-07-08 1957-10-17 Fellows Gear Shaper Co Schalt- und Vorschubeinrichtung fuer Zahnradherstellungsmaschinen
US3315665A (en) 1963-10-11 1967-04-25 Norman A Macleod Method and apparatus for therapy of skin tissue
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
CA1029288A (en) 1973-05-29 1978-04-11 William J. O'malley Silicone pressure-sensitive adhesive
US3950158A (en) 1974-05-31 1976-04-13 American Medical Products Company Urea cold pack having an inner bag provided with a perforated seal
US4231372A (en) 1974-11-04 1980-11-04 Valleylab, Inc. Safety monitoring circuit for electrosurgical unit
US4071028A (en) 1976-02-17 1978-01-31 Perkins George C Radio frequency cautery instrument and control unit therefor
US4141359A (en) 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4301794A (en) 1978-10-18 1981-11-24 Robert Tapper Method for iontophoretic treatment
US4340047A (en) 1978-10-18 1982-07-20 Robert Tapper Iontophoretic treatment apparatus
US4230105A (en) 1978-11-13 1980-10-28 Merck & Co., Inc. Transdermal delivery of drugs
WO1981003271A1 (en) 1980-05-13 1981-11-26 American Hospital Supply Corp A multipolar electrosurgical device
US4805616A (en) 1980-12-08 1989-02-21 Pao David S C Bipolar probes for ophthalmic surgery and methods of performing anterior capsulotomy
US4674499A (en) 1980-12-08 1987-06-23 Pao David S C Coaxial bipolar probe
US4406658A (en) 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
US4925671A (en) 1981-11-24 1990-05-15 Flexcon Company, Inc. Silicone pressure sensitive adhesive and uses
US5385544A (en) 1992-08-12 1995-01-31 Vidamed, Inc. BPH ablation method and apparatus
JPS60174716A (ja) 1984-02-21 1985-09-09 Yamanouchi Pharmaceut Co Ltd パツチ剤
US4655767A (en) 1984-10-29 1987-04-07 Dow Corning Corporation Transdermal drug delivery devices with amine-resistant silicone adhesives
US4747819A (en) 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US4655766A (en) 1985-08-01 1987-04-07 Alza Corporation Fluid imbibing pump with self-regulating skin patch
US4744788A (en) 1986-01-13 1988-05-17 Mercer Jr Leo C Method of using a surgical clip for cholangiography
US4722726A (en) 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4752285B1 (en) 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
US4767402A (en) 1986-07-08 1988-08-30 Massachusetts Institute Of Technology Ultrasound enhancement of transdermal drug delivery
US5042975A (en) 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US4731049A (en) 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery
US5013293A (en) 1987-05-28 1991-05-07 Drug Delivery Systems Inc. Pulsating transdermal drug delivery system
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4898920A (en) 1987-10-15 1990-02-06 Dow Corning Corporation Adhesive compositions, controlled release compositions and transdermal delivery device
DE68925030T2 (de) 1988-01-21 1996-07-25 Massachusetts Inst Technology Molekültransport durch gewebe mit der verwendung von elektroporation.
US5749847A (en) 1988-01-21 1998-05-12 Massachusetts Institute Of Technology Delivery of nucleotides into organisms by electroporation
US5547467A (en) 1988-01-21 1996-08-20 Massachusettes Institute Of Technology Method for rapid temporal control of molecular transport across tissue
WO1989006989A1 (en) 1988-01-29 1989-08-10 The Regents Of The University Of California Iontophoretic non-invasive sampling or delivery device
US5362307A (en) 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
JPH01122037U (de) 1988-02-12 1989-08-18
US4994267A (en) 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
US5438984A (en) 1988-09-08 1995-08-08 Sudor Partners Apparatus and method for the collection of analytes on a dermal patch
US5496266A (en) 1990-04-30 1996-03-05 Alza Corporation Device and method of iontophoretic drug delivery
US4927408A (en) 1988-10-03 1990-05-22 Alza Corporation Electrotransport transdermal system
US4979948A (en) 1989-04-13 1990-12-25 Purdue Research Foundation Method and apparatus for thermally destroying a layer of an organ
US5125928A (en) 1989-04-13 1992-06-30 Everest Medical Corporation Ablation catheter with selectively deployable electrodes
US5135478A (en) 1989-05-10 1992-08-04 Drug Delivery Systems Inc. Multi-signal electrical transdermal drug applicator
US5252334A (en) 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
EP0429842B1 (de) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US5036861A (en) 1990-01-11 1991-08-06 Sembrowich Walter L Method and apparatus for non-invasively monitoring plasma glucose levels
US5147916A (en) 1990-02-21 1992-09-15 Dow Corning Corporation Hot-melt silicone pressure sensitive adhesive composition and related methods and articles
US5115805A (en) 1990-02-23 1992-05-26 Cygnus Therapeutic Systems Ultrasound-enhanced delivery of materials into and through the skin
US5098430A (en) 1990-03-16 1992-03-24 Beacon Laboratories, Inc. Dual mode electrosurgical pencil
US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
US5213568A (en) * 1990-03-30 1993-05-25 Medtronic Inc. Activity controlled electrotransport drug delivery device
US5162410A (en) 1990-04-13 1992-11-10 Dow Corning Corporation Hot-melt silicon pressure sensitive adhesives with phenyl-containing siloxane fluid additive and related methods and articles
US5282799A (en) 1990-08-24 1994-02-01 Everest Medical Corporation Bipolar electrosurgical scalpel with paired loop electrodes
DE4032471C2 (de) 1990-10-12 1997-02-06 Delma Elektro Med App Elektrochirurgische Vorrichtung
US5224927A (en) 1990-11-01 1993-07-06 Robert Tapper Iontophoretic treatment system
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
US5156591A (en) 1990-12-13 1992-10-20 S. I. Scientific Innovations Ltd. Skin electrode construction and transdermal drug delivery device utilizing same
SE9101022D0 (sv) 1991-01-09 1991-04-08 Paal Svedman Medicinsk suganordning
US5182938A (en) 1991-02-22 1993-02-02 Nordson Corporation Method and apparatus for detecting bubbles in pressurized liquid dispensing systems
US5571149A (en) 1991-05-21 1996-11-05 E.P., Inc. Non-intrusive analgesic neuroaugmentive and iontophoretic delivery apparatus and management system
US5383917A (en) 1991-07-05 1995-01-24 Jawahar M. Desai Device and method for multi-phase radio-frequency ablation
US5232702A (en) 1991-07-22 1993-08-03 Dow Corning Corporation Silicone pressure sensitive adhesive compositons for transdermal drug delivery devices and related medical devices
DE69314363T2 (de) 1992-02-03 1998-02-19 Lifescan Inc Verbesserter oxidativer Kupplungsfarbstoff zur spektrophotometrischen Quantitativen Analyse von Analyten
JP2572823Y2 (ja) 1992-02-13 1998-05-25 株式会社アドバンス 簡易採血器
GB9204218D0 (en) 1992-02-27 1992-04-08 Goble Nigel M A surgical cutting tool
DK168420B1 (da) 1992-03-27 1994-03-28 Coloplast As Varmebandage
US5540681A (en) 1992-04-10 1996-07-30 Medtronic Cardiorhythm Method and system for radiofrequency ablation of tissue
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5542916A (en) 1992-08-12 1996-08-06 Vidamed, Inc. Dual-channel RF power delivery system
JPH0670987A (ja) 1992-08-28 1994-03-15 Katsuro Tachibana 薬物投与・体液採取ユニット及び装置
US5545161A (en) 1992-12-01 1996-08-13 Cardiac Pathways Corporation Catheter for RF ablation having cooled electrode with electrically insulated sleeve
US5658892A (en) 1993-01-15 1997-08-19 The General Hospital Corporation Compound delivery using high-pressure impulse transients
US5614502A (en) 1993-01-15 1997-03-25 The General Hospital Corporation High-pressure impulse transient drug delivery for the treatment of proliferative diseases
US5386837A (en) 1993-02-01 1995-02-07 Mmtc, Inc. Method for enhancing delivery of chemotherapy employing high-frequency force fields
US5993434A (en) 1993-04-01 1999-11-30 Genetronics, Inc. Method of treatment using electroporation mediated delivery of drugs and genes
US5533971A (en) 1993-09-03 1996-07-09 Alza Corporation Reduction of skin irritation during electrotransport
US5540669A (en) 1993-09-30 1996-07-30 Becton, Dickinson And Company Iontophoretic drug delivery system and method for using same
KR0134152B1 (ko) 1994-05-23 1998-04-14 이형도 의약품 투여용 피부흠집 형성장치
DE69519023T2 (de) * 1994-06-24 2001-06-13 Cygnus, Inc. Einrichtung zur iontophoretischen probennahme
US5771890A (en) 1994-06-24 1998-06-30 Cygnus, Inc. Device and method for sampling of substances using alternating polarity
US5609151A (en) 1994-09-08 1997-03-11 Medtronic, Inc. Method for R-F ablation
US5563031A (en) 1994-09-08 1996-10-08 Lifescan, Inc. Highly stable oxidative coupling dye for spectrophotometric determination of analytes
US5514130A (en) 1994-10-11 1996-05-07 Dorsal Med International RF apparatus for controlled depth ablation of soft tissue
NO180024C (no) 1994-10-11 1997-01-29 Oerjan G Martinsen Måling av fuktighet i hud
US5785705A (en) 1994-10-11 1998-07-28 Oratec Interventions, Inc. RF method for controlled depth ablation of soft tissue
JPH10510175A (ja) 1994-12-09 1998-10-06 ノバルティス アクチェンゲゼルシャフト 経皮システム
US5897553A (en) 1995-11-02 1999-04-27 Medtronic, Inc. Ball point fluid-assisted electrocautery device
US5573778A (en) 1995-03-17 1996-11-12 Adhesives Research, Inc. Drug flux enhancer-tolerant pressure sensitive adhesive composition
US5853383A (en) 1995-05-03 1998-12-29 Alza Corporation Preparation for formulations for electrotransport drug delivery
GB2303208B (en) 1995-07-08 1998-01-21 Akio Usui Viscous liquid exothermic composition,exothermic device made thereof and manufacturing method of exothermic device
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5780050A (en) 1995-07-20 1998-07-14 Theratech, Inc. Drug delivery compositions for improved stability of steroids
US5658583A (en) 1995-07-28 1997-08-19 Zhang; Jie Apparatus and methods for improved noninvasive dermal administration of pharmaceuticals
US5693052A (en) 1995-09-01 1997-12-02 Megadyne Medical Products, Inc. Coated bipolar electrocautery
US5735273A (en) 1995-09-12 1998-04-07 Cygnus, Inc. Chemical signal-impermeable mask
AU722471B2 (en) 1995-10-17 2000-08-03 Lifescan, Inc. Blood glucose strip having reduced sensitivity to hematocrit
US5718955A (en) 1996-03-12 1998-02-17 The Procter & Gamble Company Composite for controlling oxygen flux into thermal cells
US5869326A (en) 1996-09-09 1999-02-09 Genetronics, Inc. Electroporation employing user-configured pulsing scheme
US5893885A (en) 1996-11-01 1999-04-13 Cordis Webster, Inc. Multi-electrode ablation catheter
US6055043A (en) 1997-06-05 2000-04-25 Gn Nettest New York, Inc. Method and apparatus for using phase modulation to reduce coherence/polarization noise in reflectometers
US6117660A (en) 1997-06-10 2000-09-12 Cytopulse Sciences, Inc. Method and apparatus for treating materials with electrical fields having varying orientations
US6055453A (en) 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
CA2313698C (en) 1997-12-11 2008-04-15 Alza Corporation Device for enhancing transdermal agent flux
DE69806963T2 (de) 1997-12-11 2002-11-21 Alza Corp., Mountain View Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
US6104952A (en) 1998-01-07 2000-08-15 Tu; Lily Chen Devices for treating canker sores, tissues and methods thereof
US6120493A (en) 1998-01-27 2000-09-19 Genetronics, Inc. Method for the introduction of therapeutic agents utilizing an electroporation apparatus
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
DE19908737A1 (de) 1999-03-01 2000-09-28 Flabeg Gmbh Elektrochromes Element
AU761949B2 (en) * 1999-04-13 2003-06-12 Hisamitsu Pharmaceutical Co. Inc. Iontophoresis device

Also Published As

Publication number Publication date
DE60018726D1 (de) 2005-04-21
US6678554B1 (en) 2004-01-13
EP1171195A1 (de) 2002-01-16
CA2370349A1 (en) 2000-10-26
JP4180244B2 (ja) 2008-11-12
EP1171195B1 (de) 2005-03-16
DE60018726T2 (de) 2006-04-13
JP2002541935A (ja) 2002-12-10
AU4239300A (en) 2000-11-02
WO2000062857A1 (en) 2000-10-26
CA2370349C (en) 2013-01-29

Similar Documents

Publication Publication Date Title
ATE290902T1 (de) Vorrichtung zur iontophoretischen verabreichung von medikamenten mit internen sensoren
DE69133328D1 (de) Vorrichtung zur iontophoretischen verabreichung
ATE167404T1 (de) Vorrichtung zur iontophoretischen verabreichung von medikamenten und verfahren für ihre herstellung
ATE123660T1 (de) Vorrichtung und verfahren zur erneuerung von elektroden während der iontophorese.
EP1302218A3 (de) Iontophoretische auslösbare Lieferungsvorrichtung zur Verminderung von elektrischen Empfindungen
JPS63500009A (ja) 経皮薬剤アプリケ−タ用プログラマブル・コントロ−ラおよび取り付けシステム
DE69315579D1 (de) Vorrichtung zur verabreichung von medikamenten
DK0643600T3 (da) Iontoforetisk medikamentafgivelsesapparat
AU607925B2 (en) Programmable constant current source transdermal drug delivery system
MXPA02011842A (es) Dispositivo de suministro electrocinetico.
DE60110245D1 (de) Vorrichtung zur transdermalen verabreichung von medikamenten und entsprechendes herstellungsverfahren
GB1524634A (en) Atomiser devices
WO2004108209B1 (en) Electrical stimulator and garment electrode connection system
DE69220808D1 (de) Vorrichtung zur verabreichung von heilmitteln
DE60039902D1 (de) Inhalationsvernebler
CA2084734A1 (en) Iontophoresis system having features for reducing skin irritation
MX9204304A (es) Dispositivo de suministro transdermico.
WO2003002184A8 (en) Electro-acupuncture device with d-shaped stimulation electrodes
JP2001095928A (ja) イオン導入法による薬剤投入装置
ATE194296T1 (de) Vorrichtung zur transdermalen abgabe von medikamenten durch iontophorese
EP0337642A3 (de) Vorrichtung zur transdermalen Applikation von Arzneimitteln
DE69512083D1 (de) Vorrichtung zur erhöhung der wirkstoffsverabreichung durch elektrotransport
AP9700984A0 (en) Single-use device for delivering an active liquid into a body cavity.
GB2372705A (en) A hand-held self-administered iontophoretic drug applicator with roller-ball skin electrode
AU1612588A (en) Pulsating transdermal drug delivery system

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties