ATE291021T1 - Oxytocin agonisten - Google Patents

Oxytocin agonisten

Info

Publication number
ATE291021T1
ATE291021T1 AT02732974T AT02732974T ATE291021T1 AT E291021 T1 ATE291021 T1 AT E291021T1 AT 02732974 T AT02732974 T AT 02732974T AT 02732974 T AT02732974 T AT 02732974T AT E291021 T1 ATE291021 T1 AT E291021T1
Authority
AT
Austria
Prior art keywords
oxytocin agonists
general formula
compounds
agonists
group
Prior art date
Application number
AT02732974T
Other languages
English (en)
Inventor
Gary Robert William Pitt
Michael Bryan Ferring Roe
David Philip Ferring Rooker
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Application granted granted Critical
Publication of ATE291021T1 publication Critical patent/ATE291021T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Current-Collector Devices For Electrically Propelled Vehicles (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Tea And Coffee (AREA)
AT02732974T 2001-06-25 2002-06-24 Oxytocin agonisten ATE291021T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0115515.9A GB0115515D0 (en) 2001-06-25 2001-06-25 Oxytocin agonisys
PCT/GB2002/002872 WO2003000692A2 (en) 2001-06-25 2002-06-24 Oxytocin agonists

Publications (1)

Publication Number Publication Date
ATE291021T1 true ATE291021T1 (de) 2005-04-15

Family

ID=9917320

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02732974T ATE291021T1 (de) 2001-06-25 2002-06-24 Oxytocin agonisten

Country Status (22)

Country Link
US (1) US20040235753A1 (de)
EP (1) EP1399436B1 (de)
JP (1) JP2005500317A (de)
KR (1) KR20040010762A (de)
CN (1) CN1606553A (de)
AT (1) ATE291021T1 (de)
CA (1) CA2450480A1 (de)
CZ (1) CZ20033414A3 (de)
DE (1) DE60203290T2 (de)
DK (1) DK1399436T3 (de)
ES (1) ES2239717T3 (de)
GB (1) GB0115515D0 (de)
HU (1) HUP0400368A3 (de)
IL (1) IL159289A0 (de)
MX (1) MXPA03011980A (de)
NO (1) NO20035772L (de)
NZ (1) NZ530035A (de)
PL (1) PL367538A1 (de)
PT (1) PT1399436E (de)
RU (1) RU2309156C2 (de)
WO (1) WO2003000692A2 (de)
ZA (1) ZA200309626B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4179782B2 (ja) 2000-04-26 2008-11-12 富士通株式会社 無線受信装置及び無線通信システム
DK1480998T3 (da) 2002-02-27 2007-03-26 Ferring Bv Mellemprodukter og fremgangsmåder til fremstilling af heptapeptidoxytocinanaloger
EP1449844A1 (de) * 2003-02-14 2004-08-25 Ferring B.V. benzamidderivate als oxytocin-agonisten und vasopressin-antagonisten
EP1512687A1 (de) * 2003-09-05 2005-03-09 Ferring B.V. Piperazine als Oxytocin-Agonisten
EP1632494A1 (de) * 2004-08-24 2006-03-08 Ferring B.V. Vasopressin v1a antagonisten
RU2008114374A (ru) * 2005-10-24 2009-12-10 Вайет (Us) Трициклические соединения, применяемые в качестве агонистов рецептора окситоцина
BRPI0811204A8 (pt) * 2007-05-10 2015-09-22 Bristol Myers Squibb Co Tetra-hidroibenzo-1,4-diazepinas substituídas por arila e heteroarila e uso das mesmas para bloquear a recaptação de norepinefrina, dopamina e serotonina
BRPI0813230A2 (pt) * 2007-06-28 2014-12-23 Novartis Ag Moduladores de calicreína 7
US20100204107A1 (en) * 2007-09-11 2010-08-12 Dorian Bevec Use of urodilatin as a therapeutic agent
WO2009033667A2 (en) * 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
WO2009033820A2 (en) * 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
JP2010538991A (ja) * 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 治療剤としてのsfllr−ohおよびムラミルジペプチドの使用
AU2008303928A1 (en) * 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of NF-KAPPAB inhibitor SN50 and optionally angiotensin III as therapeutic agents in the treatment of EG HBV infection
AR068509A1 (es) * 2007-09-19 2009-11-18 Jerini Ag Antagosnistas del receptor de bradiquinina b1
US8853158B2 (en) 2010-05-25 2014-10-07 Institut National De La Santé Et De La Recherche Médicale (Inserm) Methods for the treatment of a feeding disorder with onset during neonate development using an agonist of the oxytocin receptor
GB201105537D0 (en) * 2011-03-31 2011-05-18 Vantia Ltd New process
CN103159641A (zh) * 2011-12-14 2013-06-19 天津泰普药品科技发展有限公司 托伐普坦中间体2-甲酸-5-(2-甲基苯甲酰氨基)甲苯的制备方法
US10442819B2 (en) 2014-12-05 2019-10-15 Merck Sharp & Dohme Corp. Tricyclic compounds as inhibitors of mutant IDH enzymes
WO2017004674A1 (en) * 2015-07-06 2017-01-12 The University Of Sydney Therapeutic compounds and compositions for treating social disorders and substance use disorders
RU2019120162A (ru) * 2016-12-12 2021-01-12 Де Юниверсити Оф Сидней Непептидные агонисты рецепторов окситоцина
KR20170035351A (ko) 2017-01-06 2017-03-30 셰플러코리아(유) 볼베어링용 케이지
MX2022002751A (es) * 2019-09-06 2022-06-29 Kinoxis Therapeutics Pty Ltd Tratamiento de la abstinencia de opioides.
EP4378526A1 (de) * 2022-11-30 2024-06-05 Université de Strasbourg Nicht peptiderge agonisten des oxytocinrezeptors
EP4378525A1 (de) * 2022-11-30 2024-06-05 Université de Strasbourg Nicht peptiderge agonisten des oxytocinrezeptors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665441B1 (fr) * 1990-07-31 1992-12-04 Sanofi Sa Derives de la n-sulfonyl indoline, leur preparation, les compositions pharmaceutiques en contenant.
PT1149096E (pt) * 1999-02-04 2003-03-31 Wyeth Corp N-oxidos de piridina triciclicos agonistas de vasopressina
GB0000079D0 (en) * 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
GB0015601D0 (en) * 2000-06-26 2000-08-16 Ferring Bv Novel antidiuretic agents

Also Published As

Publication number Publication date
US20040235753A1 (en) 2004-11-25
DK1399436T3 (da) 2005-05-30
WO2003000692A3 (en) 2003-05-15
ZA200309626B (en) 2004-05-12
HUP0400368A2 (hu) 2004-08-30
NZ530035A (en) 2004-06-25
WO2003000692A2 (en) 2003-01-03
RU2003136152A (ru) 2005-05-20
DE60203290T2 (de) 2006-02-02
PT1399436E (pt) 2005-07-29
CN1606553A (zh) 2005-04-13
CZ20033414A3 (en) 2004-05-12
EP1399436B1 (de) 2005-03-16
EP1399436A2 (de) 2004-03-24
ES2239717T3 (es) 2005-10-01
NO20035772L (no) 2003-12-22
HUP0400368A3 (en) 2007-05-29
JP2005500317A (ja) 2005-01-06
KR20040010762A (ko) 2004-01-31
CA2450480A1 (en) 2003-01-03
HK1064666A1 (en) 2005-02-04
PL367538A1 (en) 2005-02-21
DE60203290D1 (de) 2005-04-21
MXPA03011980A (es) 2004-03-26
IL159289A0 (en) 2004-06-01
GB0115515D0 (en) 2001-08-15
RU2309156C2 (ru) 2007-10-27

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