ATE291427T1 - Verwendung von optisch reinem (+)-norcisapride für die behandlung des reizdarmsyndroms - Google Patents

Verwendung von optisch reinem (+)-norcisapride für die behandlung des reizdarmsyndroms

Info

Publication number
ATE291427T1
ATE291427T1 AT99927431T AT99927431T ATE291427T1 AT E291427 T1 ATE291427 T1 AT E291427T1 AT 99927431 T AT99927431 T AT 99927431T AT 99927431 T AT99927431 T AT 99927431T AT E291427 T1 ATE291427 T1 AT E291427T1
Authority
AT
Austria
Prior art keywords
irgitable
norcisapride
treatment
bowel syndrome
optically pure
Prior art date
Application number
AT99927431T
Other languages
English (en)
Inventor
Paul D Rubin
Timothy J Barberich
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Application granted granted Critical
Publication of ATE291427T1 publication Critical patent/ATE291427T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99927431T 1998-06-15 1999-06-10 Verwendung von optisch reinem (+)-norcisapride für die behandlung des reizdarmsyndroms ATE291427T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8922498P 1998-06-15 1998-06-15
US12227599P 1999-03-01 1999-03-01
PCT/US1999/013099 WO1999065571A2 (en) 1998-06-15 1999-06-10 Use of optically pure (+)-norcisapride for treating apnea, bulimia and other disorders

Publications (1)

Publication Number Publication Date
ATE291427T1 true ATE291427T1 (de) 2005-04-15

Family

ID=26780365

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99927431T ATE291427T1 (de) 1998-06-15 1999-06-10 Verwendung von optisch reinem (+)-norcisapride für die behandlung des reizdarmsyndroms

Country Status (26)

Country Link
US (4) US6048879A (de)
EP (1) EP1089733B1 (de)
JP (1) JP2002518352A (de)
KR (3) KR20060067986A (de)
CN (1) CN1312717A (de)
AR (1) AR019671A1 (de)
AT (1) ATE291427T1 (de)
AU (1) AU4433399A (de)
BG (1) BG105096A (de)
BR (1) BR9911299A (de)
CA (1) CA2333666A1 (de)
CZ (1) CZ20004737A3 (de)
DE (1) DE69924375T2 (de)
ES (1) ES2237110T3 (de)
HK (1) HK1040058A1 (de)
HU (1) HUP0102203A3 (de)
IL (1) IL140118A0 (de)
IS (1) IS5756A (de)
NO (1) NO20006357L (de)
NZ (3) NZ526943A (de)
PL (1) PL345275A1 (de)
PT (1) PT1089733E (de)
SI (1) SI1089733T1 (de)
SK (1) SK19052000A3 (de)
TR (7) TR200103055T2 (de)
WO (1) WO1999065571A2 (de)

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US20060241164A1 (en) * 1998-02-27 2006-10-26 The Board Of Trustees Of The University Of Illinoi Pharmacological treatment for sleep apnea
US7160898B2 (en) * 2001-12-14 2007-01-09 Board Of Trustees Of The University Of Illinois Pharmacological treatment for sleep apnea
TR200003707T2 (tr) 1998-06-15 2001-06-21 Sepracor Inc. Apne , bulimi ve başka bozuklukların tedavi edilmesi için optik açıdan saf (-) norsisapridin kullanımı
WO2000051582A2 (en) * 1999-03-01 2000-09-08 Sepracor Inc. Methods for treating apnea and apnea disorders using optically pure r(+)ondansetron
EP1435238A1 (de) * 1999-03-01 2004-07-07 Sepracor Inc. Verfahren zur Behandlung von Apnoe und Apnoe-Erkrankungen mit optisch reinem R(+)Ondansetron
US6353005B1 (en) 1999-03-02 2002-03-05 Sepracor, Inc. Method and compositions using (+) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist
CA2817619A1 (en) 2001-06-08 2002-12-08 Abbott Laboratories (Bermuda) Ltd. Methods of administering anti-tnf.alpha. antibodies
US20040220153A1 (en) * 2002-09-24 2004-11-04 Jost-Price Edward Roydon Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
US7613515B2 (en) * 2003-02-03 2009-11-03 Enteromedics Inc. High frequency vagal blockage therapy
US7444183B2 (en) * 2003-02-03 2008-10-28 Enteromedics, Inc. Intraluminal electrode apparatus and method
US20040172084A1 (en) 2003-02-03 2004-09-02 Knudson Mark B. Method and apparatus for treatment of gastro-esophageal reflux disease (GERD)
US7844338B2 (en) * 2003-02-03 2010-11-30 Enteromedics Inc. High frequency obesity treatment
US20050070974A1 (en) * 2003-09-29 2005-03-31 Knudson Mark B. Obesity and eating disorder stimulation treatment with neural block
US20050070970A1 (en) * 2003-09-29 2005-03-31 Knudson Mark B. Movement disorder stimulation with neural block
US7803195B2 (en) * 2004-06-03 2010-09-28 Mayo Foundation For Medical Education And Research Obesity treatment and device
US20060020298A1 (en) * 2004-07-20 2006-01-26 Camilleri Michael L Systems and methods for curbing appetite
US20060020277A1 (en) * 2004-07-20 2006-01-26 Gostout Christopher J Gastric reshaping devices and methods
US7833279B2 (en) * 2004-11-12 2010-11-16 Enteromedics Inc. Pancreatic exocrine secretion diversion apparatus and method
JP2008524332A (ja) 2004-12-20 2008-07-10 コレジウム ファーマシューティカル， インク． 睡眠傷害のための医薬組成物
US7822486B2 (en) * 2005-08-17 2010-10-26 Enteromedics Inc. Custom sized neural electrodes
US7672727B2 (en) * 2005-08-17 2010-03-02 Enteromedics Inc. Neural electrode treatment
GB0524668D0 (en) * 2005-12-02 2006-01-11 Novartis Ag Organic compounds
WO2007098202A2 (en) 2006-02-16 2007-08-30 Imthera Medical, Inc. An rfid based apparatus, system, and method for therapeutic treatment of a patient
JP2011500143A (ja) 2007-10-09 2011-01-06 イムセラ・メディカル・インコーポレーテッド 選択的刺激のための装置、システム、及び方法
WO2010042404A1 (en) 2008-10-09 2010-04-15 Imthera Medical, Inc. Method of stimulating a hypoglossal nerve for controlling the position of a patient's tongue
AU2010318651A1 (en) 2009-11-10 2012-05-03 Imthera Medical, Inc. System for stimulating a hypoglossal nerve for controlling the position of a patient's tongue
US8825164B2 (en) 2010-06-11 2014-09-02 Enteromedics Inc. Neural modulation devices and methods
WO2015134747A1 (en) 2014-03-06 2015-09-11 Mayo Foundation For Medical Education And Research Apparatus and methods of inducing weight loss using blood flow control

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Also Published As

Publication number Publication date
KR20010052739A (ko) 2001-06-25
WO1999065571A2 (en) 1999-12-23
NO20006357L (no) 2001-02-13
KR20060017570A (ko) 2006-02-23
HUP0102203A3 (en) 2001-12-28
IS5756A (is) 2000-12-08
TR200103055T2 (tr) 2002-06-21
EP1089733A2 (de) 2001-04-11
TR200103057T2 (tr) 2002-06-21
PL345275A1 (en) 2001-12-03
TR200103059T2 (tr) 2002-06-21
PT1089733E (pt) 2005-08-31
HK1040058A1 (zh) 2002-05-24
BR9911299A (pt) 2001-03-13
AU4433399A (en) 2000-01-05
CA2333666A1 (en) 1999-12-23
TR200103054T2 (tr) 2002-06-21
NZ526943A (en) 2004-11-26
TR200103058T2 (tr) 2002-06-21
DE69924375T2 (de) 2005-08-11
WO1999065571A3 (en) 2000-04-20
KR20060067986A (ko) 2006-06-20
NZ508824A (en) 2003-10-31
US6048879A (en) 2000-04-11
US6835740B2 (en) 2004-12-28
CZ20004737A3 (cs) 2001-10-17
HUP0102203A2 (hu) 2001-11-28
IL140118A0 (en) 2002-02-10
TR200003708T2 (tr) 2001-06-21
SI1089733T1 (en) 2005-06-30
JP2002518352A (ja) 2002-06-25
CN1312717A (zh) 2001-09-12
ES2237110T3 (es) 2005-07-16
US6369079B1 (en) 2002-04-09
US20020147220A1 (en) 2002-10-10
BG105096A (en) 2002-02-28
SK19052000A3 (sk) 2001-06-11
EP1089733B1 (de) 2005-03-23
TR200103056T2 (tr) 2002-06-21
AR019671A1 (es) 2002-03-13
NO20006357D0 (no) 2000-12-13
DE69924375D1 (de) 2005-04-28
US20050154018A1 (en) 2005-07-14
NZ535135A (en) 2006-04-28

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