ATE292974T1 - Arsentrioxidfreie arsensulfidverbindungen zur behandlung von hämatologischen tumoren - Google Patents

Arsentrioxidfreie arsensulfidverbindungen zur behandlung von hämatologischen tumoren

Info

Publication number
ATE292974T1
ATE292974T1 AT98930630T AT98930630T ATE292974T1 AT E292974 T1 ATE292974 T1 AT E292974T1 AT 98930630 T AT98930630 T AT 98930630T AT 98930630 T AT98930630 T AT 98930630T AT E292974 T1 ATE292974 T1 AT E292974T1
Authority
AT
Austria
Prior art keywords
arsentic
rioxide
treatment
arsenic sulfide
sulfide compounds
Prior art date
Application number
AT98930630T
Other languages
English (en)
Inventor
Daopei Lu
Original Assignee
Daopei Lu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daopei Lu filed Critical Daopei Lu
Application granted granted Critical
Publication of ATE292974T1 publication Critical patent/ATE292974T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/36—Arsenic; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Treating Waste Gases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Iron (AREA)
AT98930630T 1998-04-24 1998-07-06 Arsentrioxidfreie arsensulfidverbindungen zur behandlung von hämatologischen tumoren ATE292974T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN98101635A CN1233476A (zh) 1998-04-24 1998-04-24 治疗急性白血病的药物及其制备方法
PCT/CN1998/000118 WO1999055344A1 (en) 1998-04-24 1998-07-06 Arsenic sulfide compounds and derivatives thereof for the treatment of malignancies

Publications (1)

Publication Number Publication Date
ATE292974T1 true ATE292974T1 (de) 2005-04-15

Family

ID=5216829

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98930630T ATE292974T1 (de) 1998-04-24 1998-07-06 Arsentrioxidfreie arsensulfidverbindungen zur behandlung von hämatologischen tumoren

Country Status (18)

Country Link
US (2) US6733792B1 (de)
EP (2) EP1552841A1 (de)
JP (1) JP2002512967A (de)
KR (1) KR100610388B1 (de)
CN (2) CN1233476A (de)
AT (1) ATE292974T1 (de)
AU (1) AU748795B2 (de)
BR (1) BR9815825A (de)
CA (1) CA2328165A1 (de)
DE (1) DE69829782T2 (de)
ES (1) ES2242286T3 (de)
ID (1) ID27299A (de)
IL (1) IL139208A (de)
NO (1) NO20005315D0 (de)
NZ (2) NZ526746A (de)
PL (1) PL344410A1 (de)
TR (1) TR200003117T2 (de)
WO (1) WO1999055344A1 (de)

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FR2781674B1 (fr) * 1998-07-31 2002-06-28 Inst Nat Sante Rech Med Utilisation de nouveaux agents inducteurs de mort cellulaire en synergie avec les interferons
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AUPR379801A0 (en) 2001-03-19 2001-04-12 Unisearch Limited Use of a substantially cell membrane impermeable compound for treating arthritis
AUPR874601A0 (en) 2001-11-08 2001-11-29 Unisearch Limited Selective targeting of apoptotic cells
EP1474128B1 (de) 2002-01-07 2016-06-01 Board Of Regents, The University Of Texas System S-dimethylarsino-thiosuccinsäure,s-dimethylarsino-2-thiobenzoesäure, s-(dimethylarsino)-glutathion zur krebsbehandlung
US8394422B2 (en) * 2002-04-26 2013-03-12 Centre National De La Recherche Scientifique (Cnrs) Arsenic therapy for autoimmune and/or inflammatory diseases in mice and humans
FR2838965B1 (fr) 2002-04-26 2004-06-25 Centre Nat Rech Scient Therapie par l'arsenic du syndrome autoimmunlymphoproliferatif de type apls chez la souris comme chez l'homme
US20030235571A1 (en) * 2002-06-19 2003-12-25 Gabriel Gojon-Romanillos Systemic treatment of pathological conditions resulting from oxidative stress and/or redox imbalance
EP1563099B1 (de) 2002-11-07 2009-07-22 Newsouth Innovations Pty Limited Induktion der mitochondrialen permeabilitätstransition
EP2641611A3 (de) * 2003-10-17 2013-12-18 Novo Nordisk A/S Kombinationstherapie
TWI411431B (zh) * 2004-07-16 2013-10-11 Texas A & M Univ Sys 有機砷化合物、其用於治療癌症之用途及包含其之醫藥組成物
EP1721615A1 (de) 2005-05-09 2006-11-15 Komipharm International Co., Ltd. Pharmazeutische Zusammensetzung enthaltend Natrium- oder Kaliumarsenit zur Behandlung von Urogenitalkrebs und seinen Metastasen
JP4994374B2 (ja) * 2005-07-29 2012-08-08 ジオファーム オンコロジー， インコーポレイテッド がんを治療するための化合物および方法
US20070134349A1 (en) * 2005-09-19 2007-06-14 Duke University Methods of treating hematological malignancies
US20080233207A1 (en) * 2006-01-04 2008-09-25 Sheptovitsky Yelena G Injectable and Infusable Mercury Compositions and Methods for Treating Cancer
TW200829261A (en) * 2006-09-29 2008-07-16 Ziopharm Oncology Inc Method for controlling angiogenesis in animals
EP2069371B1 (de) 2006-11-01 2013-03-13 NewSouth Innovations Pty Limited Organo-arsenoxid-verbindungen und deren verwendung
CN101903029B (zh) * 2007-11-02 2012-09-26 Zio医药肿瘤学公司 使用有机砷化物的联合治疗
WO2009075870A1 (en) * 2007-12-12 2009-06-18 Ziopharm Oncology, Inc. Compounds and methods for the treatment of cancer
PT2321012T (pt) 2008-08-20 2019-01-11 Solasia Pharma K K Compostos organoarsénicos e métodos para o tratamento de cancro
CA2772411C (en) * 2009-09-10 2017-08-22 Kominox, Inc. Cancer stem cell-targeted and drug resistant cancer therapy
EP3409289B1 (de) 2010-02-26 2020-09-30 Novo Nordisk A/S Stabile, antikörperhaltige zusammensetzungen
RU2012153786A (ru) 2010-05-28 2014-07-10 Ново Нордиск А/С Стабильные многодозовые композиции, содержащие антитело и консервант
FR3004949B1 (fr) * 2013-04-26 2016-02-05 Centre Nat Rech Scient Traitement de maladies autoimmunes et inflammatoires par les composes de l'arsenic as203 et/ou as205 administres par voie locale
CN104434971A (zh) * 2014-02-28 2015-03-25 贺鹏程 一种用于治疗急性早幼粒细胞白血病的复方制剂、及其药物组合物、应用和制备方法
CN108498542A (zh) * 2017-02-24 2018-09-07 四川兴科蓉药业有限责任公司 β-As4S4在制备用于治疗血液系统恶性肿瘤的药物中的用途
WO2019134070A1 (en) * 2018-01-02 2019-07-11 Rui Jin Hospital, Shanghai Jiao Tong University School Of Medicine Panda as novel therapeutic
CN108338990A (zh) * 2018-04-11 2018-07-31 中国医学科学院基础医学研究所 水溶性雄黄固体分散体在制备骨髓造血干/祖细胞红系分化诱导剂中的应用
CN109528646A (zh) * 2018-11-21 2019-03-29 南京泽恒医药技术开发有限公司 一种巯嘌呤混悬液及其制备方法
CN110101713A (zh) * 2019-05-16 2019-08-09 上海交通大学医学院附属第九人民医院 一种三氧化二砷组合物的应用
US20220226372A1 (en) * 2019-05-21 2022-07-21 Medsenic Use of metal ions to potentiate the therapeutic effects of arsenic
CN112870225B (zh) * 2021-02-05 2023-01-06 北京大学人民医院 一种用于高危急性早幼粒细胞白血病诱导期的联合治疗药物
CN116338184B (zh) * 2023-04-24 2025-09-16 峰春源医疗器械(深圳)有限公司 一种高安全性新冠病毒抗原检测试剂盒
NL2039297B1 (en) * 2024-12-11 2025-07-18 Inst Chinese Materia Medica China Academy Of Cms Application of Realgar in the Preparation of Drugs for The Prevention and/or Treatment of Acute Promyelocytic Leukemia

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TR200002243T2 (tr) * 1997-11-10 2000-12-21 Memorial Sloan-Kettering Cancer Center Arsenik trioksitin hazırlanması için işlem ve bunların kanser tedavisi için kullanımı.

Also Published As

Publication number Publication date
DE69829782T2 (de) 2006-03-09
CN1233476A (zh) 1999-11-03
CN1299284A (zh) 2001-06-13
TR200003117T2 (tr) 2001-03-21
NO20005315L (no) 2000-10-20
CA2328165A1 (en) 1999-11-04
HK1034466A1 (en) 2001-10-26
US20040028750A1 (en) 2004-02-12
ID27299A (id) 2001-03-22
KR100610388B1 (ko) 2006-08-09
EP1077709A1 (de) 2001-02-28
NZ526746A (en) 2005-01-28
BR9815825A (pt) 2000-12-12
AU8100998A (en) 1999-11-16
CN1175823C (zh) 2004-11-17
IL139208A (en) 2005-08-31
EP1077709B1 (de) 2005-04-13
NO20005315D0 (no) 2000-10-20
ES2242286T3 (es) 2005-11-01
PL344410A1 (en) 2001-11-05
JP2002512967A (ja) 2002-05-08
IL139208A0 (en) 2001-11-25
DE69829782D1 (de) 2005-05-19
WO1999055344A1 (en) 1999-11-04
EP1077709A4 (de) 2002-06-19
NZ508240A (en) 2003-08-29
US6733792B1 (en) 2004-05-11
EP1552841A1 (de) 2005-07-13
KR20010071160A (ko) 2001-07-28
US7138147B2 (en) 2006-11-21
AU748795B2 (en) 2002-06-13

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