ATE293454T1 - Thrombopoietinzusammensetzungen - Google Patents
ThrombopoietinzusammensetzungenInfo
- Publication number
- ATE293454T1 ATE293454T1 AT96914753T AT96914753T ATE293454T1 AT E293454 T1 ATE293454 T1 AT E293454T1 AT 96914753 T AT96914753 T AT 96914753T AT 96914753 T AT96914753 T AT 96914753T AT E293454 T1 ATE293454 T1 AT E293454T1
- Authority
- AT
- Austria
- Prior art keywords
- thrombopoietin
- compositions
- methods
- physiologically acceptable
- adsorption
- Prior art date
Links
- 102000036693 Thrombopoietin Human genes 0.000 title abstract 5
- 108010041111 Thrombopoietin Proteins 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 238000001179 sorption measurement Methods 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 229920005862 polyol Polymers 0.000 abstract 1
- 150000003077 polyols Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/196—Thrombopoietin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Treatment Of Steel In Its Molten State (AREA)
- Display Devices Of Pinball Game Machines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/486,451 US6790439B1 (en) | 1995-06-07 | 1995-06-07 | Thrombopoietin compositions |
| PCT/US1996/007463 WO1996040217A1 (en) | 1995-06-07 | 1996-05-22 | Thrombopoietin compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE293454T1 true ATE293454T1 (de) | 2005-05-15 |
Family
ID=23931938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96914753T ATE293454T1 (de) | 1995-06-07 | 1996-05-22 | Thrombopoietinzusammensetzungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6790439B1 (de) |
| EP (1) | EP0831886B1 (de) |
| JP (2) | JP3479082B2 (de) |
| KR (1) | KR100265222B1 (de) |
| AT (1) | ATE293454T1 (de) |
| AU (1) | AU696944B2 (de) |
| CA (1) | CA2223446A1 (de) |
| DE (1) | DE69634633T2 (de) |
| NZ (2) | NZ505602A (de) |
| TW (1) | TW443934B (de) |
| WO (1) | WO1996040217A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW497972B (en) * | 1995-06-08 | 2002-08-11 | Kirin Brewery | Stable thrombopoietin (TPO)-containing lyophilized compositions |
| US6267958B1 (en) * | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| AU4344697A (en) * | 1996-10-04 | 1998-04-24 | Amgen, Inc. | Pharmaceutical compositions containing an mpl ligand |
| AU2005317166B2 (en) * | 2004-12-15 | 2009-09-10 | Biovitrum Ab (Publ) | Therapeutic formulations of keratinocyte growth factor |
| US7879318B2 (en) | 2006-01-23 | 2011-02-01 | Mcw Research Foundation, Inc. | Method of reducing the effects of ischemia by administration of a thrombopoietin receptor ligand |
| WO2008086025A2 (en) * | 2007-01-10 | 2008-07-17 | Edison Pharmaceuticals, Inc. | Treatment of respiratory chain disorders using compounds having erythropoietin or thrombopoietin activity |
| CA2683317C (en) * | 2007-04-26 | 2014-12-16 | Bayer Healthcare Llc | Stabilization of liquid solutions of recombinant protein for frozen storage |
| US20090291092A1 (en) * | 2008-05-22 | 2009-11-26 | Miller Guy M | Treatment of mitochondrial diseases with an erythropoietin mimetic |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3325223A1 (de) | 1983-07-13 | 1985-01-24 | Hoechst Ag, 6230 Frankfurt | Gegen denaturierung bestaendige, waessrige proteinloesungen, verfahren zu ihrer herstellung und ihre verwendung |
| US5096885A (en) | 1988-04-15 | 1992-03-17 | Genentech, Inc. | Human growth hormone formulation |
| JPH02268681A (ja) * | 1989-04-07 | 1990-11-02 | Green Cross Corp:The | ウロキナーゼ前駆体の安定化方法及び乾燥製剤 |
| US5344644A (en) * | 1991-08-01 | 1994-09-06 | Takeda Chemical Industries, Ltd. | Water-soluble composition for sustained-release |
| DK0955062T3 (da) | 1992-07-31 | 2007-09-17 | Genentech Inc | Vandig formulering indeholdende humant væksthormon |
| US5358708A (en) * | 1993-01-29 | 1994-10-25 | Schering Corporation | Stabilization of protein formulations |
| NZ260909A (en) * | 1993-07-05 | 1995-04-27 | Takeda Chemical Industries Ltd | Production of sustained release preparation by allowing a water-soluble polypeptide to permeate into a biodegradable matrix in an aqueous solution |
| US5580856A (en) * | 1994-07-15 | 1996-12-03 | Prestrelski; Steven J. | Formulation of a reconstituted protein, and method and kit for the production thereof |
-
1995
- 1995-06-07 US US08/486,451 patent/US6790439B1/en not_active Expired - Lifetime
-
1996
- 1996-05-22 NZ NZ505602A patent/NZ505602A/en unknown
- 1996-05-22 KR KR1019970709023A patent/KR100265222B1/ko not_active Expired - Fee Related
- 1996-05-22 NZ NZ308395A patent/NZ308395A/xx unknown
- 1996-05-22 AT AT96914753T patent/ATE293454T1/de not_active IP Right Cessation
- 1996-05-22 EP EP96914753A patent/EP0831886B1/de not_active Expired - Lifetime
- 1996-05-22 WO PCT/US1996/007463 patent/WO1996040217A1/en not_active Ceased
- 1996-05-22 JP JP50067397A patent/JP3479082B2/ja not_active Expired - Fee Related
- 1996-05-22 CA CA002223446A patent/CA2223446A1/en not_active Abandoned
- 1996-05-22 AU AU58023/96A patent/AU696944B2/en not_active Ceased
- 1996-05-22 DE DE69634633T patent/DE69634633T2/de not_active Expired - Fee Related
- 1996-06-26 TW TW085107698A patent/TW443934B/zh not_active IP Right Cessation
-
2000
- 2000-02-10 JP JP2000033823A patent/JP2000198745A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US6790439B1 (en) | 2004-09-14 |
| EP0831886B1 (de) | 2005-04-20 |
| KR100265222B1 (ko) | 2000-09-15 |
| AU696944B2 (en) | 1998-09-24 |
| DE69634633D1 (en) | 2005-05-25 |
| WO1996040217A1 (en) | 1996-12-19 |
| KR19990022542A (ko) | 1999-03-25 |
| NZ505602A (en) | 2001-11-30 |
| DE69634633T2 (de) | 2006-05-18 |
| AU5802396A (en) | 1996-12-30 |
| NZ308395A (en) | 2000-08-25 |
| JP2000198745A (ja) | 2000-07-18 |
| EP0831886A1 (de) | 1998-04-01 |
| TW443934B (en) | 2001-07-01 |
| JP3479082B2 (ja) | 2003-12-15 |
| JPH10510841A (ja) | 1998-10-20 |
| CA2223446A1 (en) | 1996-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0831886 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |