ATE293699T1 - Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligand - Google Patents
Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligandInfo
- Publication number
- ATE293699T1 ATE293699T1 AT96904817T AT96904817T ATE293699T1 AT E293699 T1 ATE293699 T1 AT E293699T1 AT 96904817 T AT96904817 T AT 96904817T AT 96904817 T AT96904817 T AT 96904817T AT E293699 T1 ATE293699 T1 AT E293699T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor
- nucleotide sequence
- expression cassette
- target
- polypeptide
- Prior art date
Links
- 230000014509 gene expression Effects 0.000 title abstract 9
- 239000003446 ligand Substances 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title abstract 2
- 108700001094 Plant Genes Proteins 0.000 title 1
- 230000023603 positive regulation of transcription initiation, DNA-dependent Effects 0.000 title 1
- 108020003175 receptors Proteins 0.000 abstract 7
- 102000005962 receptors Human genes 0.000 abstract 7
- 239000002773 nucleotide Substances 0.000 abstract 6
- 125000003729 nucleotide group Chemical group 0.000 abstract 6
- 229920001184 polypeptide Polymers 0.000 abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 6
- 230000001105 regulatory effect Effects 0.000 abstract 4
- 230000001276 controlling effect Effects 0.000 abstract 2
- 230000009418 agronomic effect Effects 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 108020001756 ligand binding domains Proteins 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8217—Gene switch
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
- C12N15/8289—Male sterility
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
- C12N15/829—Female sterility
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- High Energy & Nuclear Physics (AREA)
- Endocrinology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39803795A | 1995-03-03 | 1995-03-03 | |
| PCT/EP1996/000686 WO1996027673A1 (en) | 1995-03-03 | 1996-02-19 | Control of gene expression in plants by receptor mediated transactivation in the presence of a chemical ligand |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE293699T1 true ATE293699T1 (de) | 2005-05-15 |
Family
ID=23573749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96904817T ATE293699T1 (de) | 1995-03-03 | 1996-02-19 | Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligand |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US5880333A (de) |
| EP (1) | EP0813604B1 (de) |
| JP (1) | JPH11500922A (de) |
| AT (1) | ATE293699T1 (de) |
| AU (1) | AU703124B2 (de) |
| CA (1) | CA2213340C (de) |
| DE (1) | DE69634630T2 (de) |
| ES (1) | ES2237764T3 (de) |
| HU (1) | HUP9800353A3 (de) |
| WO (1) | WO1996027673A1 (de) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8901677D0 (en) | 1989-01-26 | 1989-03-15 | Ici Plc | Hybrid seed production |
| ATE293699T1 (de) | 1995-03-03 | 2005-05-15 | Syngenta Participations Ag | Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligand |
| PL323587A1 (en) | 1995-05-26 | 1998-04-14 | Zeneca Ltd | Gene changing-over system including edisone receptor |
| WO1997013864A1 (en) * | 1995-10-10 | 1997-04-17 | Novartis Ag | Juvenile hormone or one of its agonists as a chemical ligand to control gene expression in plants by receptor mediated transactivation |
| US6610828B1 (en) | 1996-05-24 | 2003-08-26 | Syngenta Limited | Heliothis ecdysone receptor |
| EP0823480A1 (de) * | 1996-08-06 | 1998-02-11 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Kontrollierte Genexpression in Pflanzen |
| GB9703681D0 (en) * | 1997-02-21 | 1997-04-09 | Gene Shears Pty Ltd | Protein complemention |
| US6784340B1 (en) * | 1998-01-28 | 2004-08-31 | The Rockefeller University | Chemical inducible promoter used to obtain transgenic plants with a silent marker |
| PT1054985E (pt) | 1998-02-20 | 2012-07-03 | Syngenta Ltd | Produção de semente híbrida |
| US6333318B1 (en) * | 1998-05-14 | 2001-12-25 | The Salk Institute For Biological Studies | Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto |
| US6258603B1 (en) * | 1998-06-17 | 2001-07-10 | Rohm And Haas Company | Ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
| CA2336207C (en) | 1998-09-10 | 2004-03-23 | Pioneer Hi-Bred International, Inc. | Ecdysone receptors and methods for their use |
| GB9828660D0 (en) | 1998-12-24 | 1999-02-17 | Cambridge Advanced Tech | Control of gene expression in eukaryotes |
| US7420049B2 (en) * | 1999-06-18 | 2008-09-02 | Ceres, Inc. | Sequence-determined DNA fragments encoding AP2 domain proteins |
| US20060235218A1 (en) * | 1999-12-08 | 2006-10-19 | Nickolai Alexandrov | Sequence-determined DNA fragments encoding thioredoxin proteins |
| WO2001062780A1 (en) * | 2000-02-24 | 2001-08-30 | The Salk Institute For Biological Studies | Gene expression system based on chimeric receptors |
| EP1263977A2 (de) | 2000-02-28 | 2002-12-11 | Yale University | Verfahren und zusammensetzungen zur reduction oder eliminierung der verbreitung eines transgens |
| AU2001249315A1 (en) | 2000-03-22 | 2001-10-03 | Rheogene, Inc. | Ecdysone receptor-based inducible gene expression system |
| US20040033600A1 (en) | 2001-03-21 | 2004-02-19 | Palli Subba Reddy | Ecdysone receptor-based inducible gene expression system |
| AU2011213797B2 (en) * | 2000-03-22 | 2013-05-02 | Intrexon Corporation | Ecdysone receptor-based inducible gene expression system |
| AU2001252944A1 (en) * | 2000-03-24 | 2001-10-08 | City Of Hope | Methods of modulating drug clearance mechanisms by altering SXR activity |
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| EP1356066A2 (de) * | 2000-10-24 | 2003-10-29 | Syngenta Participations AG | Kontrolle der pflanzengenexpression |
| WO2002057293A2 (en) | 2001-01-22 | 2002-07-25 | Sangamo Biosciences, Inc. | Modified zinc finger binding proteins |
| WO2002066614A2 (en) * | 2001-02-20 | 2002-08-29 | Rheogene Holdings, Inc. | Chimeric retinoid x receptors and their use in a novel ecdysone receptor-based inducible gene expression system |
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| EP1373470B1 (de) | 2001-02-20 | 2013-04-24 | Intrexon Corporation | Neue substitutionsmutantenrezeptoren und ihre verwendung in einem induzierbaren genexpressionssystem auf basis eines nukleären rezeptors |
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| WO2015009760A1 (en) | 2013-07-15 | 2015-01-22 | Donald Danforth Plant Science Center | Enhanced oil production and stress tolerance in plants |
| AU2015317862A1 (en) | 2014-09-17 | 2017-04-06 | Intrexon Corporation | Boron-containing diacylhydrazine compounds |
| UY37343A (es) | 2016-07-25 | 2018-02-28 | Intrexon Corp | Control del fenotipo en plantas |
| WO2018076335A1 (en) | 2016-10-31 | 2018-05-03 | Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences | Compositions and methods for enhancing abiotic stress tolerance |
| WO2018089527A1 (en) | 2016-11-09 | 2018-05-17 | Intrexon Corporation | Frataxin expression constructs |
| EP3568474A1 (de) | 2017-01-10 | 2019-11-20 | Intrexon Corporation | Modulation der expression von polypeptiden über neue genschalterexpressionssysteme |
| CA3065930A1 (en) | 2017-06-07 | 2018-12-13 | Intrexon Corporation | Expression of novel cell tags |
| IL277128B2 (en) | 2018-03-06 | 2025-11-01 | Precigen Inc | Hepatitis b vaccines and uses of the same |
| KR20250136930A (ko) | 2018-03-06 | 2025-09-16 | 프레시전 인코포레이티드 | 사람 파필로마바이러스 백신 및 이의 용도 |
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| US4833080A (en) * | 1985-12-12 | 1989-05-23 | President And Fellows Of Harvard College | Regulation of eucaryotic gene expression |
| GB8901677D0 (en) * | 1989-01-26 | 1989-03-15 | Ici Plc | Hybrid seed production |
| US5262300A (en) * | 1988-11-30 | 1993-11-16 | The Salk Institute For Biological Studies | Receptors: their identification, characterization, preparation and use |
| ES2152920T3 (es) * | 1990-02-09 | 2001-02-16 | Salk Inst For Biological Studi | Composiciones receptoras de retinoides y metodos. |
| AU7492291A (en) * | 1990-02-26 | 1991-09-18 | Board Of Trustees Of The Leland Stanford Junior University | Identification and expression of insect steroid receptor dna sequences |
| JPH11508121A (ja) * | 1990-03-22 | 1999-07-21 | ザ ソーク インスティテュート フォア バイオロジカル スタディーズ | 昆虫レチノイドレセプター組成物および方法 |
| CA2042447C (en) * | 1990-06-12 | 1999-09-28 | Marc C. Albertsen | Control of microsporogenesis by externally inducible promoter sequences |
| CA2100582A1 (en) * | 1991-03-18 | 1992-09-19 | David J. Mangelsdorf | Response element compositions and assays employing same |
| WO1993003162A1 (en) * | 1991-08-08 | 1993-02-18 | Genentech, Inc. | Ecdysteroid dependent regulation of genes in mammalian cells |
| EP0611395A1 (de) * | 1991-11-05 | 1994-08-24 | Novartis AG | Aussergewoehnlich suesser mais |
| GB9123554D0 (en) * | 1991-11-06 | 1992-01-02 | Hamilton John G | Ventilation device |
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| EP0745121B1 (de) * | 1992-05-14 | 2007-06-20 | Baylor College Of Medicine | Mutierte steroidhormonrezeptoren, methoden für ihre benutzung und molekularer schalter für gentherapie |
| CA2137462A1 (en) * | 1992-07-02 | 1994-01-20 | Ronald M. Evans | Multimeric forms of members of the steroid/thyroid superfamily of receptors with the ultraspiracle receptor |
| US5409823A (en) * | 1992-09-24 | 1995-04-25 | Ciba-Geigy Corporation | Methods for the production of hybrid seed |
| US5691196A (en) * | 1992-12-31 | 1997-11-25 | American Cyanamid Company | Recombinant nucleic acid containing a response element |
| IL110298A (en) * | 1993-07-13 | 1999-04-11 | Brann Mark Robert | Identification of ligands by selective amplification of cells transfected with receptors |
| ATE293699T1 (de) | 1995-03-03 | 2005-05-15 | Syngenta Participations Ag | Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligand |
| PL323587A1 (en) * | 1995-05-26 | 1998-04-14 | Zeneca Ltd | Gene changing-over system including edisone receptor |
-
1996
- 1996-02-19 AT AT96904817T patent/ATE293699T1/de not_active IP Right Cessation
- 1996-02-19 WO PCT/EP1996/000686 patent/WO1996027673A1/en not_active Ceased
- 1996-02-19 DE DE69634630T patent/DE69634630T2/de not_active Expired - Lifetime
- 1996-02-19 ES ES96904817T patent/ES2237764T3/es not_active Expired - Lifetime
- 1996-02-19 EP EP96904817A patent/EP0813604B1/de not_active Expired - Lifetime
- 1996-02-19 CA CA2213340A patent/CA2213340C/en not_active Expired - Fee Related
- 1996-02-19 JP JP8526556A patent/JPH11500922A/ja active Pending
- 1996-02-19 AU AU48782/96A patent/AU703124B2/en not_active Ceased
- 1996-02-19 HU HU9800353A patent/HUP9800353A3/hu unknown
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1998
- 1998-01-21 US US09/010,050 patent/US5880333A/en not_active Expired - Lifetime
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1999
- 1999-01-20 US US09/234,190 patent/US6147282A/en not_active Expired - Lifetime
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- 2001-03-21 US US09/813,589 patent/US6939711B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5880333A (en) | 1999-03-09 |
| AU703124B2 (en) | 1999-03-18 |
| DE69634630D1 (de) | 2005-05-25 |
| EP0813604A1 (de) | 1997-12-29 |
| ES2237764T3 (es) | 2005-08-01 |
| HUP9800353A3 (en) | 2001-01-29 |
| WO1996027673A1 (en) | 1996-09-12 |
| US6939711B2 (en) | 2005-09-06 |
| HUP9800353A2 (hu) | 1998-05-28 |
| CA2213340A1 (en) | 1996-09-12 |
| US20010022004A1 (en) | 2001-09-13 |
| JPH11500922A (ja) | 1999-01-26 |
| CA2213340C (en) | 2011-07-26 |
| DE69634630T2 (de) | 2005-11-10 |
| US6147282A (en) | 2000-11-14 |
| EP0813604B1 (de) | 2005-04-20 |
| AU4878296A (en) | 1996-09-23 |
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