ATE294162T1 - Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid - Google Patents
Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochloridInfo
- Publication number
- ATE294162T1 ATE294162T1 AT02767318T AT02767318T ATE294162T1 AT E294162 T1 ATE294162 T1 AT E294162T1 AT 02767318 T AT02767318 T AT 02767318T AT 02767318 T AT02767318 T AT 02767318T AT E294162 T1 ATE294162 T1 AT E294162T1
- Authority
- AT
- Austria
- Prior art keywords
- lercanidipine hydrochloride
- solvates
- crystalline forms
- lercanidipine
- hydrochloride
- Prior art date
Links
- WMFYOYKPJLRMJI-UHFFFAOYSA-N Lercanidipine hydrochloride Chemical compound Cl.COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)(C)CN(C)CCC(C=2C=CC=CC=2)C=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 WMFYOYKPJLRMJI-UHFFFAOYSA-N 0.000 title 2
- 229960002162 lercanidipine hydrochloride Drugs 0.000 title 2
- 239000012453 solvate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001MI001727A ITMI20011727A1 (it) | 2001-08-06 | 2001-08-06 | Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi |
| PCT/EP2002/008700 WO2003014085A1 (en) | 2001-08-06 | 2002-08-05 | Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE294162T1 true ATE294162T1 (de) | 2005-05-15 |
Family
ID=11448246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02767318T ATE294162T1 (de) | 2001-08-06 | 2002-08-05 | Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1423367B1 (de) |
| JP (1) | JP2005502648A (de) |
| KR (1) | KR100912664B1 (de) |
| CN (1) | CN100494175C (de) |
| AR (1) | AR037230A1 (de) |
| AT (1) | ATE294162T1 (de) |
| AU (1) | AU2002331390B2 (de) |
| BR (1) | BR0211738A (de) |
| DE (1) | DE60203919D1 (de) |
| EA (1) | EA200400279A1 (de) |
| ES (1) | ES2209684T1 (de) |
| HR (1) | HRP20040157A2 (de) |
| HU (1) | HUP0401161A3 (de) |
| IL (2) | IL153916A0 (de) |
| IT (1) | ITMI20011727A1 (de) |
| MX (1) | MXPA04001073A (de) |
| NO (1) | NO20040479L (de) |
| PE (1) | PE20030350A1 (de) |
| PL (1) | PL369449A1 (de) |
| UY (1) | UY27409A1 (de) |
| WO (1) | WO2003014085A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100651212B1 (ko) | 2004-10-27 | 2006-12-01 | 제일약품주식회사 | 무정형 레르카니디핀의 제조방법 |
| AR052918A1 (es) | 2005-02-25 | 2007-04-11 | Recordati Ireland Ltd | Clorhidrato de lercanidipina amorfo |
| WO2007031865A2 (en) | 2005-09-16 | 2007-03-22 | Glenmark Pharmaceuticals Limited | Polymorphic form of lercanidipine hydrochloride and process for the preparation thereof |
| CN101868442A (zh) * | 2007-03-05 | 2010-10-20 | 阿克塔维什集团Ptc公司 | 盐酸乐卡地平多晶型物和1,1,n-三甲基-n-(3,3-二苯基丙基)-2-氨基乙酰醋酸乙酯的改进制法 |
| WO2008136393A1 (ja) * | 2007-04-27 | 2008-11-13 | Ajinomoto Co., Inc. | ラクタム化合物の結晶形およびその製造方法 |
| EP2585051B2 (de) | 2010-06-23 | 2020-04-08 | KRKA, tovarna zdravil, d.d., Novo mesto | Pharmazeutische orale dosierformen mit lercandipin und enalapril und ihren pharmazeutisch akzeptablen salzen |
| WO2012085249A2 (en) | 2010-12-24 | 2012-06-28 | Krka, D.D., Novo Mesto | Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8403866D0 (en) * | 1984-02-14 | 1984-03-21 | Recordati Chem Pharm | Diphenylalkylaminoalkyl esters |
| US5912351A (en) * | 1995-05-12 | 1999-06-15 | Recordati, S.A. Chemical And Pharmaceutical Company | Anhydrous 1,4-Dihydropyridines and salts thereof |
-
2001
- 2001-08-06 IT IT2001MI001727A patent/ITMI20011727A1/it unknown
-
2002
- 2002-08-02 AR ARP020102957A patent/AR037230A1/es not_active Application Discontinuation
- 2002-08-05 EP EP02767318A patent/EP1423367B1/de not_active Expired - Lifetime
- 2002-08-05 PL PL02369449A patent/PL369449A1/xx unknown
- 2002-08-05 HU HU0401161A patent/HUP0401161A3/hu unknown
- 2002-08-05 WO PCT/EP2002/008700 patent/WO2003014085A1/en not_active Ceased
- 2002-08-05 MX MXPA04001073A patent/MXPA04001073A/es not_active Application Discontinuation
- 2002-08-05 JP JP2003519035A patent/JP2005502648A/ja active Pending
- 2002-08-05 ES ES02767318T patent/ES2209684T1/es active Pending
- 2002-08-05 EA EA200400279A patent/EA200400279A1/ru unknown
- 2002-08-05 KR KR1020047001791A patent/KR100912664B1/ko not_active Expired - Fee Related
- 2002-08-05 CN CNB028155114A patent/CN100494175C/zh not_active Expired - Fee Related
- 2002-08-05 DE DE60203919T patent/DE60203919D1/de not_active Expired - Lifetime
- 2002-08-05 AT AT02767318T patent/ATE294162T1/de not_active IP Right Cessation
- 2002-08-05 HR HR20040157A patent/HRP20040157A2/hr not_active Application Discontinuation
- 2002-08-05 IL IL15391602A patent/IL153916A0/xx unknown
- 2002-08-05 BR BR0211738-0A patent/BR0211738A/pt not_active IP Right Cessation
- 2002-08-05 AU AU2002331390A patent/AU2002331390B2/en not_active Ceased
- 2002-08-06 UY UY27409A patent/UY27409A1/es not_active Application Discontinuation
- 2002-08-06 PE PE2002000716A patent/PE20030350A1/es not_active Application Discontinuation
-
2003
- 2003-01-13 IL IL153916A patent/IL153916A/en unknown
-
2004
- 2004-02-03 NO NO20040479A patent/NO20040479L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0401161A3 (en) | 2009-04-28 |
| CN1538958A (zh) | 2004-10-20 |
| WO2003014085A1 (en) | 2003-02-20 |
| KR20040030932A (ko) | 2004-04-09 |
| IL153916A0 (en) | 2003-07-31 |
| EP1423367A1 (de) | 2004-06-02 |
| DE60203919D1 (de) | 2005-06-02 |
| NO20040479L (no) | 2004-02-03 |
| EA200400279A1 (ru) | 2004-06-24 |
| MXPA04001073A (es) | 2005-02-17 |
| HUP0401161A2 (hu) | 2004-09-28 |
| EP1423367B1 (de) | 2005-04-27 |
| HRP20040157A2 (en) | 2004-08-31 |
| IL153916A (en) | 2008-07-08 |
| CN100494175C (zh) | 2009-06-03 |
| AR037230A1 (es) | 2004-11-03 |
| BR0211738A (pt) | 2004-09-28 |
| AU2002331390B2 (en) | 2008-06-05 |
| KR100912664B1 (ko) | 2009-08-17 |
| UY27409A1 (es) | 2003-03-31 |
| PL369449A1 (en) | 2005-04-18 |
| ITMI20011727A0 (it) | 2001-08-06 |
| ES2209684T1 (es) | 2004-07-01 |
| ITMI20011727A1 (it) | 2003-02-06 |
| JP2005502648A (ja) | 2005-01-27 |
| PE20030350A1 (es) | 2003-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |