ATE294188T1 - Peptidische inhibitoren der lfa-1/icam-1 interaktion - Google Patents
Peptidische inhibitoren der lfa-1/icam-1 interaktionInfo
- Publication number
- ATE294188T1 ATE294188T1 AT01942364T AT01942364T ATE294188T1 AT E294188 T1 ATE294188 T1 AT E294188T1 AT 01942364 T AT01942364 T AT 01942364T AT 01942364 T AT01942364 T AT 01942364T AT E294188 T1 ATE294188 T1 AT E294188T1
- Authority
- AT
- Austria
- Prior art keywords
- icam
- interaction
- lfa
- peptidic inhibitors
- peptidic
- Prior art date
Links
- 102100022339 Integrin alpha-L Human genes 0.000 title abstract 2
- 102000015271 Intercellular Adhesion Molecule-1 Human genes 0.000 title abstract 2
- 108010064593 Intercellular Adhesion Molecule-1 Proteins 0.000 title abstract 2
- 108010064548 Lymphocyte Function-Associated Antigen-1 Proteins 0.000 title abstract 2
- 230000003993 interaction Effects 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 102000001189 Cyclic Peptides Human genes 0.000 abstract 1
- 108010069514 Cyclic Peptides Proteins 0.000 abstract 1
- 208000002250 Hematologic Neoplasms Diseases 0.000 abstract 1
- 208000032464 Retinoic acid syndrome Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/483,550 US6649592B1 (en) | 2000-01-14 | 2000-01-14 | Peptide inhibitors of LFA-1/ICAM-1 interaction |
| US09/760,599 US6630447B2 (en) | 2000-01-14 | 2001-01-16 | Peptide inhibitors of LFA-1/ICAM-1 interaction |
| PCT/US2001/001382 WO2001051508A1 (en) | 2000-01-14 | 2001-01-16 | Peptide inhibitors of lfa-1/icam-1 interaction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE294188T1 true ATE294188T1 (de) | 2005-05-15 |
Family
ID=27047693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01942364T ATE294188T1 (de) | 2000-01-14 | 2001-01-16 | Peptidische inhibitoren der lfa-1/icam-1 interaktion |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6630447B2 (de) |
| EP (1) | EP1263778B1 (de) |
| AT (1) | ATE294188T1 (de) |
| AU (1) | AU777721B2 (de) |
| CA (1) | CA2397485A1 (de) |
| DE (1) | DE60110396T2 (de) |
| WO (1) | WO2001051508A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8680059B2 (en) | 1998-05-20 | 2014-03-25 | Biotempt B.V. | Oligopeptide acetate and formulations thereof |
| US6844315B2 (en) | 1998-05-20 | 2005-01-18 | Erasmus Universiteit Rotterdam | Immunoregulator |
| EP1138692A1 (de) | 2000-03-29 | 2001-10-04 | Erasmus Universiteit Rotterdam | Fragmente des menschlichen Choriongonadotropins als Immunoregulatoren |
| US20030220258A1 (en) | 2001-12-21 | 2003-11-27 | Robbert Benner | Treatment of ischemic events |
| USRE43279E1 (en) | 2000-03-29 | 2012-03-27 | Biotemp B.V. | Compositions capable of reducing elevated blood urea concentration |
| US7358330B2 (en) | 2001-03-29 | 2008-04-15 | Biotempt B.V. | Immunoregulatory compositions |
| US7786084B2 (en) | 2001-12-21 | 2010-08-31 | Biotempt B.V. | Treatment of burns |
| US7560433B2 (en) | 2001-12-21 | 2009-07-14 | Biotempt B.V. | Treatment of multiple sclerosis (MS) |
| WO2004032861A2 (en) | 2002-10-11 | 2004-04-22 | Bristol-Myers Squibb Company | Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents |
| US20050048579A1 (en) * | 2003-07-07 | 2005-03-03 | Larson Richard S. | Tertiary structures of ICAM-1/LFA-1 modulators |
| US20050119186A1 (en) * | 2003-07-22 | 2005-06-02 | Larson Richard S. | Potent peptide inhibitors and methods of use |
| CA2544678C (en) | 2003-11-05 | 2013-12-31 | Sunesis Pharmaceuticals, Inc. | Modulators of cellular adhesion |
| TW200616634A (en) | 2004-10-01 | 2006-06-01 | Bristol Myers Squibb Co | Crystalline forms and process for preparing spiro-hydantoin compounds |
| US7186727B2 (en) | 2004-12-14 | 2007-03-06 | Bristol-Myers Squibb Company | Pyridyl-substituted spiro-hydantoin compounds and use thereof |
| DK2444079T3 (en) | 2005-05-17 | 2017-01-30 | Sarcode Bioscience Inc | Compositions and Methods for the Treatment of Eye Diseases |
| JP4846799B2 (ja) | 2005-07-05 | 2011-12-28 | バイオテンプト ベー.フェー. | 腫瘍の治療 |
| EP1864692A1 (de) | 2006-06-07 | 2007-12-12 | Biotempt B.V. | Verwendung von peptiden zum Schutz von Strahlenschäden |
| CN101443080B (zh) * | 2006-03-07 | 2015-01-14 | 比奥滕普特公司 | 肽在控制辐射损伤中的用途 |
| ES2830024T3 (es) | 2007-10-19 | 2021-06-02 | Novartis Ag | Composiciones y métodos para el tratamiento del edema macular |
| WO2009128934A1 (en) | 2008-04-15 | 2009-10-22 | Sarcode Corporation | Topical lfa-1 antagonists for use in localized treatment of immune related disorders |
| US8623322B2 (en) | 2008-06-13 | 2014-01-07 | Stc.Unm | Non-invasive diagnostic agents and methods of diagnosing infectious disease |
| WO2020163876A1 (en) * | 2019-02-08 | 2020-08-13 | The Regents Of The University Of California | Compositions and methods involving layilin |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9613112D0 (en) * | 1996-06-21 | 1996-08-28 | Zeneca Ltd | Chemical compounds |
-
2001
- 2001-01-16 DE DE60110396T patent/DE60110396T2/de not_active Expired - Fee Related
- 2001-01-16 CA CA002397485A patent/CA2397485A1/en not_active Abandoned
- 2001-01-16 US US09/760,599 patent/US6630447B2/en not_active Expired - Lifetime
- 2001-01-16 EP EP01942364A patent/EP1263778B1/de not_active Expired - Lifetime
- 2001-01-16 WO PCT/US2001/001382 patent/WO2001051508A1/en not_active Ceased
- 2001-01-16 AU AU29502/01A patent/AU777721B2/en not_active Ceased
- 2001-01-16 AT AT01942364T patent/ATE294188T1/de not_active IP Right Cessation
-
2003
- 2003-07-08 US US10/615,479 patent/US20050065070A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6630447B2 (en) | 2003-10-07 |
| AU2950201A (en) | 2001-07-24 |
| EP1263778A1 (de) | 2002-12-11 |
| WO2001051508A1 (en) | 2001-07-19 |
| AU777721B2 (en) | 2004-10-28 |
| US20050065070A1 (en) | 2005-03-24 |
| DE60110396D1 (de) | 2005-06-02 |
| DE60110396T2 (de) | 2006-01-19 |
| EP1263778B1 (de) | 2005-04-27 |
| US20010034326A1 (en) | 2001-10-25 |
| CA2397485A1 (en) | 2001-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |