ATE294813T1 - Konjugate von gallensäure mit metallbindenden chelatverbdingungen und die verwendung davon - Google Patents

Konjugate von gallensäure mit metallbindenden chelatverbdingungen und die verwendung davon

Info

Publication number
ATE294813T1
ATE294813T1 AT01911677T AT01911677T ATE294813T1 AT E294813 T1 ATE294813 T1 AT E294813T1 AT 01911677 T AT01911677 T AT 01911677T AT 01911677 T AT01911677 T AT 01911677T AT E294813 T1 ATE294813 T1 AT E294813T1
Authority
AT
Austria
Prior art keywords
bale
conjugates
binding
acid
metal
Prior art date
Application number
AT01911677T
Other languages
English (en)
Inventor
Haen Christoph De
Andrea Beltrami
Enrico Cappelletti
Luciano Lattuada
Mario Virtuani
Original Assignee
Bracco Imaging Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa
Application granted granted Critical
Publication of ATE294813T1 publication Critical patent/ATE294813T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
AT01911677T 2000-02-29 2001-02-21 Konjugate von gallensäure mit metallbindenden chelatverbdingungen und die verwendung davon ATE294813T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI000383A IT1317862B1 (it) 2000-02-29 2000-02-29 Coniugati di acidi biliari con chelati complessi di ioni metallici eloro uso.
PCT/EP2001/001971 WO2001064708A1 (en) 2000-02-29 2001-02-21 Bile acids conjugates with metal ion chelates and the use thereof

Publications (1)

Publication Number Publication Date
ATE294813T1 true ATE294813T1 (de) 2005-05-15

Family

ID=11444243

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01911677T ATE294813T1 (de) 2000-02-29 2001-02-21 Konjugate von gallensäure mit metallbindenden chelatverbdingungen und die verwendung davon

Country Status (8)

Country Link
US (1) US6803030B2 (de)
EP (1) EP1259532B1 (de)
JP (1) JP5052726B2 (de)
AT (1) ATE294813T1 (de)
AU (1) AU4064401A (de)
DE (1) DE60110558T2 (de)
IT (1) IT1317862B1 (de)
WO (1) WO2001064708A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318485B1 (it) * 2000-04-21 2003-08-25 Bracco Spa Uso di derivati di acidi biliari coniugati con complessi di ionimetallici nella visualizzazione diagnostica di sistemi microvascolari
EP1506402A2 (de) * 2002-03-28 2005-02-16 Rutgers, The State University of New Jersey Bis-übergangsmetall-chelat probe
US6919333B2 (en) * 2002-11-12 2005-07-19 Rutgers, The State University Of New Jersey Bis-transition-metal-chelate probes
ATE435035T1 (de) * 2003-01-13 2009-07-15 Bracco Imaging Spa Verbesserte linker für radiopharmazeutische verbindungen
US8420050B2 (en) * 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7226577B2 (en) * 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
US7611692B2 (en) * 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7850947B2 (en) 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
DE102004038134B4 (de) 2004-08-05 2013-07-25 Johann Wolfgang Goethe-Universität Frankfurt am Main Multivalente Chelatoren zum Modifizieren und Organisieren von Zielmolekülen, Verfahren zu ihrer Herstellung sowie ihre Verwendung
JP2008508333A (ja) * 2004-08-05 2008-03-21 ヨハン ウォルフガング ゲーテ−ウニベルジテート フランクフルト アム マイン 標的分子の改変および組織化のための多価キレーター
JP2008528245A (ja) * 2005-02-03 2008-07-31 エピックス ファーマシューティカルズ，インコーポレイテッド 定常状態灌流方法
EP2147684A1 (de) 2008-07-22 2010-01-27 Bracco Imaging S.p.A Selektiv gegen Metallproteasen wirkende Diagnosemittel
BR112015023747B1 (pt) 2013-03-15 2023-04-18 Brigham Young University Uso de um composto antimicrobiano catiônico esteroide (csa) para a preparação de uma composição para tratar, reduzir, ou prevenir inflamação aguda ou crônica e/ou dor aguda ou crônica associada com uma doença ou um sintoma de doença
US11524015B2 (en) 2013-03-15 2022-12-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
US10227376B2 (en) * 2014-08-22 2019-03-12 Brigham Young University Radiolabeled cationic steroid antimicrobials and diagnostic methods
EP3101012A1 (de) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft Neue gadoliniumchelat-verbindung zur verwendung in der magnetresonanzbildgebung
US10226550B2 (en) 2016-03-11 2019-03-12 Brigham Young University Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
RU2755181C2 (ru) 2016-11-28 2021-09-14 Байер Фарма Акциенгезельшафт Новые хелатные соединения гадолиния с высокой релаксивностью для применения в магнитно-резонансной визуализации
US10959433B2 (en) 2017-03-21 2021-03-30 Brigham Young University Use of cationic steroidal antimicrobials for sporicidal activity
IL321215B2 (en) 2018-11-23 2026-05-01 Bayer Ag Contrast media formulation and process for its preparation
US12186328B2 (en) 2019-05-23 2025-01-07 Brigham Young University Use of CSA compounds to stimulate stem cells and hair growth
CN119350421A (zh) * 2024-09-03 2025-01-24 重庆大学 一种一锅法制备沙蟾毒精氨基甲酸酯类化合物的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057302A (en) * 1987-02-13 1991-10-15 Abbott Laboratories Bifunctional chelating agents
NO940115D0 (no) 1994-01-13 1994-01-13 Nycomed Imaging As Kontrastmidler for roentgen- og magnettomografisk avbildning
GB9407812D0 (en) * 1994-04-20 1994-06-15 Nycomed Salutar Inc Compounds
IT1269839B (it) * 1994-05-26 1997-04-15 Bracco Spa Coniugati di acidi biliari, loro derivati con complessi metallici e relativi usi
IT1283218B1 (it) * 1996-03-08 1998-04-16 Bracco Spa Polichelanti, loro complessi con ioni metallici, loro preparazione e loro usi
IT1304501B1 (it) * 1998-12-23 2001-03-19 Bracco Spa Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza

Also Published As

Publication number Publication date
JP2003525306A (ja) 2003-08-26
EP1259532A1 (de) 2002-11-27
DE60110558D1 (de) 2005-06-09
ITMI20000383A1 (it) 2001-08-29
AU4064401A (en) 2001-09-12
US20030113265A1 (en) 2003-06-19
WO2001064708A1 (en) 2001-09-07
DE60110558T2 (de) 2005-09-22
JP5052726B2 (ja) 2012-10-17
EP1259532B1 (de) 2005-05-04
US6803030B2 (en) 2004-10-12
IT1317862B1 (it) 2003-07-15
ITMI20000383A0 (it) 2000-02-29

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