ATE295200T1 - Hautbehandlungsvorrichtung zur verlängerten transdermalen verabreichung von medikamenten - Google Patents

Hautbehandlungsvorrichtung zur verlängerten transdermalen verabreichung von medikamenten

Info

Publication number
ATE295200T1
ATE295200T1 AT00984209T AT00984209T ATE295200T1 AT E295200 T1 ATE295200 T1 AT E295200T1 AT 00984209 T AT00984209 T AT 00984209T AT 00984209 T AT00984209 T AT 00984209T AT E295200 T1 ATE295200 T1 AT E295200T1
Authority
AT
Austria
Prior art keywords
skin
stretching
micropathways
medications
treatment device
Prior art date
Application number
AT00984209T
Other languages
English (en)
Inventor
Michel J N Cormier
Joseph C Trautman
Hyunok L Kim
Ahmad P Samiee
Armand P Neukermans
Bruce P Edwards
Wai-Loong Lim
Andrew I Poutiatine
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE295200T1 publication Critical patent/ATE295200T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT00984209T 1999-12-10 2000-12-07 Hautbehandlungsvorrichtung zur verlängerten transdermalen verabreichung von medikamenten ATE295200T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17270499P 1999-12-10 1999-12-10
PCT/US2000/033582 WO2001041864A1 (en) 1999-12-10 2000-12-07 Skin treatment apparatus for sustained transdermal drug delivery

Publications (1)

Publication Number Publication Date
ATE295200T1 true ATE295200T1 (de) 2005-05-15

Family

ID=22628847

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00984209T ATE295200T1 (de) 1999-12-10 2000-12-07 Hautbehandlungsvorrichtung zur verlängerten transdermalen verabreichung von medikamenten

Country Status (19)

Country Link
US (2) US20020111600A1 (de)
EP (1) EP1239917B1 (de)
JP (1) JP4312407B2 (de)
KR (1) KR100832754B1 (de)
CN (1) CN100402106C (de)
AT (1) ATE295200T1 (de)
AU (1) AU782610B2 (de)
CA (1) CA2393537C (de)
DE (1) DE60020159T2 (de)
DK (1) DK1239917T3 (de)
ES (1) ES2238333T3 (de)
HK (1) HK1048773B (de)
HU (1) HU225467B1 (de)
IL (1) IL150091A0 (de)
MX (1) MXPA02005765A (de)
NO (1) NO323128B1 (de)
PT (1) PT1239917E (de)
WO (1) WO2001041864A1 (de)
ZA (1) ZA200204597B (de)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6595947B1 (en) * 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US6440096B1 (en) * 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
RU2272618C2 (ru) * 2000-09-08 2006-03-27 Алза Корпорейшн Способы ингибирования уменьшения трансдермального движения лекарственного средства посредством ингибирования закрытия путей
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US6821281B2 (en) 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
US6663820B2 (en) * 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
US20040120964A1 (en) * 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
EP1439870B1 (de) * 2001-10-29 2009-01-14 Becton, Dickinson and Company Vorrichtung für die abgabe einer substanz
JP4435569B2 (ja) * 2001-11-26 2010-03-17 ソニー ドイチュラント ゲゼルシャフト ミット ベシュレンクテル ハフツング 常温に近い温度で製造され及び動作する、化学的検出材料としての半導体材料の用途
US7578954B2 (en) 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
KR20060108682A (ko) * 2003-10-24 2006-10-18 알자 코포레이션 경피 약물 전달을 증대시키기 위한 전처리 방법 및 장치
KR20060113730A (ko) * 2003-12-18 2006-11-02 노보 노르디스크 에이/에스 피부 스트레칭 수단을 가진 노즐 장치
CA2552385C (en) * 2003-12-29 2013-07-23 3M Innovative Properties Company Medical devices and kits including same
AU2005228145B2 (en) 2004-03-24 2011-03-03 Corium Pharma Solutions, Inc. Transdermal delivery device
US7591806B2 (en) * 2004-05-18 2009-09-22 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
ATE504328T1 (de) 2004-11-18 2011-04-15 3M Innovative Properties Co Mikronadelanordungsapplikator und halter
KR20070102669A (ko) 2004-11-18 2007-10-19 쓰리엠 이노베이티브 프로퍼티즈 컴파니 로우-프로파일 미세 바늘 어레이 인가 장치
WO2006108185A1 (en) 2005-04-07 2006-10-12 3M Innovative Properties Company System and method for tool feedback sensing
US8048017B2 (en) * 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US8043250B2 (en) * 2005-05-18 2011-10-25 Nanomed Devices, Inc. High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
WO2007002523A2 (en) 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
CA2613111C (en) 2005-06-27 2015-05-26 3M Innovative Properties Company Microneedle array applicator device and method of array application
US20070078414A1 (en) * 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
EP2258441A3 (de) * 2005-09-02 2011-09-21 Intercell USA, Inc. Vorrichtungen für die transkutane Abgabe von Vakzinen und transdermale Abgabe von Arzneimitteln
WO2007064486A1 (en) 2005-11-30 2007-06-07 3M Innovative Properties Company Microneedle arrays and methods of use thereof
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US20080214987A1 (en) * 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
US10525246B2 (en) 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
JP5553612B2 (ja) 2007-01-22 2014-07-16 コリウム インターナショナル, インコーポレイテッド マイクロニードルアレイ用アプリケータ
WO2008130587A2 (en) 2007-04-16 2008-10-30 Corium International, Inc. Solvent-cast microneedle arrays containing active
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
US8150505B2 (en) * 2007-05-03 2012-04-03 Path Scientific, Llc Method and apparatus for the formation of multiple microconduits
CA2695731C (en) * 2007-08-06 2018-04-03 Transderm, Inc. Microneedle arrays formed from polymer films
US8876856B2 (en) * 2007-12-24 2014-11-04 Peter Ar-Fu Lam Human skin treatment arrangement
US8940013B2 (en) * 2007-12-24 2015-01-27 Peter Ar-Fu Lam Human skin treatment arrangement
US9066738B2 (en) * 2008-07-14 2015-06-30 Syneron Medical Ltd. Devices and methods for percutaneous energy delivery
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル, インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
US20130012891A1 (en) * 2011-07-05 2013-01-10 Yossi Gross Skin-treatment and drug-delivery devices
US20140316323A1 (en) * 2011-11-16 2014-10-23 The Royal Institution for the Advancement of Learn ing/ Mcgill University Device, use thereof and method for reducing scarring of wound
EP2931356B1 (de) 2012-12-14 2019-03-06 Mindera Corporation Verfahren und vorrichtungen zur erkennung und erfassung von biomarkern
RU2698095C2 (ru) 2012-12-21 2019-08-22 Кориум Интернэшнл, Инк. Микроматрица для доставки терапевтического средства и способы использования
BR122020006959B1 (pt) 2013-03-12 2022-04-26 Corium, Inc Aplicador de microprojeções
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
WO2014144973A1 (en) 2013-03-15 2014-09-18 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
AU2014233695A1 (en) 2013-03-15 2015-10-01 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
US10194935B2 (en) * 2013-12-31 2019-02-05 L'oreal Shear-induced dermal infusion
WO2015122838A1 (en) * 2014-02-14 2015-08-20 Chee Yen Lim Rapidly dissolvable microneedles with drug-impregnated tips
US20160279401A1 (en) 2015-03-27 2016-09-29 Allergan, Inc. Dissolvable microneedles for skin treatment
EP3188714A1 (de) 2014-09-04 2017-07-12 Corium International, Inc. Mikrostrukturanordnung, verfahren zur herstellung und verfahren zur verwendung
CA3238290A1 (en) 2015-04-17 2016-10-20 Georgia Tech Research Corporation Drug delivery device with housing and separable microneedles
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
WO2017135474A1 (en) * 2016-02-05 2017-08-10 Nitto Denko Corporation Transdermal permeant application device
CN106492341B (zh) * 2016-11-11 2019-07-26 王春花 粉雾眉的纹绣控制方法及装置
EP3582752A1 (de) 2017-02-17 2019-12-25 Allergan, Inc. Mikronadelanordnung mit wirkstoff
US12433510B2 (en) 2017-12-21 2025-10-07 Georgia Tech Research Corporation Methods and systems for improved collection of interstitial fluid
CN108245742A (zh) * 2018-01-19 2018-07-06 苏州英诺迈医学科技服务有限公司 一种胰岛素注射装置
US20210007887A1 (en) * 2018-03-27 2021-01-14 Kao Corporation Heating implement
JP6647607B1 (ja) * 2019-04-25 2020-02-14 株式会社グリーンフィールド 開口器具及び人工芝への固定具の打ち込み方法
JP7267549B2 (ja) * 2019-05-14 2023-05-02 学校法人 関西大学 穿刺補助具
CN115666635A (zh) * 2020-05-04 2023-01-31 新泽西州立罗格斯大学 使用抽吸来增强细胞的透化和转染的系统和方法
KR20230165746A (ko) 2020-11-30 2023-12-05 민데라 코포레이션 마이크로니들 디바이스 및 방법, 및 피부 병태 어세이
CN117813069A (zh) * 2021-06-16 2024-04-02 尼欧迪纳生物科学公司 具有可移除的毂的张紧式输注系统
JP2024154435A (ja) * 2021-07-21 2024-10-31 テルモ株式会社 血管穿刺支援装置
CN114632259B (zh) * 2022-02-23 2024-09-03 黄雄仙 防漏上药的瘢痕上药设备
CN120478822B (zh) * 2025-06-24 2025-10-28 西安市新希望医疗器械有限公司 一种定向型中药透皮施药设备

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
US4114619A (en) * 1975-11-21 1978-09-19 Wolfgang Wagner Automatic injecting apparatus
US4787888A (en) * 1987-06-01 1988-11-29 University Of Connecticut Disposable piezoelectric polymer bandage for percutaneous delivery of drugs and method for such percutaneous delivery (a)
EP0429842B1 (de) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
JP2936678B2 (ja) * 1990-09-05 1999-08-23 アイシン精機株式会社 クラツクセンサーを用いた暖房便座
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
SE9101022D0 (sv) * 1991-01-09 1991-04-08 Paal Svedman Medicinsk suganordning
US5199952A (en) * 1991-04-09 1993-04-06 Morf, Inc. Bird injection system
US5171215A (en) * 1991-08-22 1992-12-15 Flanagan Dennis F Endermic method and apparatus
JPH05199952A (ja) * 1992-01-30 1993-08-10 Matsushita Electric Ind Co Ltd 電動送風機
US5486196A (en) * 1992-02-13 1996-01-23 Medchem Products, Inc. Apparatus for the closure of wide skin defects by stretching of skin
CA2205444A1 (en) 1994-12-09 1996-06-13 Novartis Ag Transdermal system
AU5869796A (en) 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
WO1996037155A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
DE19525607A1 (de) * 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5857983A (en) * 1996-05-17 1999-01-12 Mercury Diagnostics, Inc. Methods and apparatus for sampling body fluid
KR100453132B1 (ko) * 1996-12-20 2004-10-15 앨자 코포레이션 경피 약제 플럭스를 향상시키기 위한 장치 및 방법
US5860957A (en) * 1997-02-07 1999-01-19 Sarcos, Inc. Multipathway electronically-controlled drug delivery system
PT1037686E (pt) * 1997-12-11 2005-10-31 Alza Corp Aparelho para potenciar o fluxo de agente transdermico
CN1161164C (zh) * 1997-12-11 2004-08-11 阿尔扎有限公司 用于通过体表导入或提取质剂的装置
JP2000189453A (ja) * 1998-12-28 2000-07-11 Nichiban Co Ltd 医療用粘着テ―プ
WO2000074763A2 (en) * 1999-06-04 2000-12-14 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance

Also Published As

Publication number Publication date
CA2393537A1 (en) 2001-06-14
EP1239917B1 (de) 2005-05-11
MXPA02005765A (es) 2003-01-28
ES2238333T3 (es) 2005-09-01
ZA200204597B (en) 2004-09-29
NO20022721D0 (no) 2002-06-07
KR20020060996A (ko) 2002-07-19
CA2393537C (en) 2009-02-03
DE60020159D1 (de) 2005-06-16
KR100832754B1 (ko) 2008-05-27
NO323128B1 (no) 2007-01-08
JP2003516205A (ja) 2003-05-13
EP1239917A1 (de) 2002-09-18
CN1423571A (zh) 2003-06-11
US20040181203A1 (en) 2004-09-16
CN100402106C (zh) 2008-07-16
HUP0204002A2 (en) 2003-03-28
HK1048773A1 (en) 2003-04-17
JP4312407B2 (ja) 2009-08-12
US20020111600A1 (en) 2002-08-15
IL150091A0 (en) 2002-12-01
DK1239917T3 (da) 2005-08-22
AU2087001A (en) 2001-06-18
HU225467B1 (en) 2006-12-28
AU782610B2 (en) 2005-08-11
NO20022721L (no) 2002-08-07
DE60020159T2 (de) 2005-10-06
HK1048773B (en) 2005-10-14
WO2001041864A1 (en) 2001-06-14
PT1239917E (pt) 2005-08-31

Similar Documents

Publication Publication Date Title
DE60020159D1 (de) Hautbehandlungsvorrichtung zur verlängerten transdermalen verabreichung von medikamenten
CA2416383A1 (en) Solution-, dispersion- or emulsion-producing film dermatics
AU2074301A (en) Device and method for enhancing microprotrusion skin piercing
DE50313125D1 (de) Medizinischer Clip
BR0215804A (pt) Sistema e método para movimento e distensão de tecido plástico
MX9101787A (es) Formulaciones,metodos y dispositivos anticonceptivos transdermicos
MXPA02008423A (es) Dispositivo para tratamiento con aupresion y metodos para su uso.
DE60122919D1 (de) Gesichtsmaske mit streck-und rückzugsfähigkeiten
DK0486863T3 (da) Antacidum-præparat med forlænget opholdstid i maven
DK0770384T3 (da) Faste, vandfrie farmaceutiske sammensætninger til vaginal anvendelse
WO2004034872A3 (en) Ambulatory cyclic traction device
ES1036662Y (es) Dispositivo para el estiramiento y el aumento de la flexibilidad del pie.
EA200501402A1 (ru) Устройство для анальгезирующей иммобилизации сломанных рёбер
ZA892091B (en) Rolled matrix device having enhanced ability to unroll and method for its production
DE60141596D1 (de) Transdermales system zur verabreichung von loratadin und dessen verwendung
UA26091C2 (uk) Основа для одержання препарату, який впливає hа ткаhинний обміh і модулює процеси імуhітету в біологічhих системах, та біологічhо активhа харчова добавка "міпро-віт"
DK0637956T3 (da) Anvendelse af remacemid til behandling af Parkinsonˆs sygdom
ES1029783Y (es) Dispositivo para el tratamiento del sindrome y rehabilitacion en el heroinomano.
RU2000125849A (ru) Устройство для создания физиологической гиперкапнии у человека
ATE383467T1 (de) Bahnbehandlungsvorrichtung mit befeuchtungseinrichtung
RU99114798A (ru) Устройство для гиперкоррекции мужского полового члена
ATE530698T1 (de) Textilbehandlungsvorrichtung
BR8001274U (pt) Dispositivo de contenção
ES1030503Y (es) Dispositivo para sujetar y fijar el remate del cosido de un calzado.
LT2002101A (en) A mechanical massage device

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1239917

Country of ref document: EP

REN Ceased due to non-payment of the annual fee