ATE295745T1 - Hyaluronsäure-gel, verfahren zur dessen herstellung und hyaluronsäure-gel enthaltendes medizinisches material - Google Patents

Hyaluronsäure-gel, verfahren zur dessen herstellung und hyaluronsäure-gel enthaltendes medizinisches material

Info

Publication number
ATE295745T1
ATE295745T1 AT98936706T AT98936706T ATE295745T1 AT E295745 T1 ATE295745 T1 AT E295745T1 AT 98936706 T AT98936706 T AT 98936706T AT 98936706 T AT98936706 T AT 98936706T AT E295745 T1 ATE295745 T1 AT E295745T1
Authority
AT
Austria
Prior art keywords
hyaluronic acid
acid gel
production
material containing
medical material
Prior art date
Application number
AT98936706T
Other languages
English (en)
Inventor
Yoshiaki Miyata
Akio Okamoto
Masatoshi Kawada
Kazuhiro Oshima
Masamichi Hashimoto
Kazuhiko Arai
Tomio Sawada
Original Assignee
Denki Kagaku Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Denki Kagaku Kogyo Kk filed Critical Denki Kagaku Kogyo Kk
Application granted granted Critical
Publication of ATE295745T1 publication Critical patent/ATE295745T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98936706T 1997-08-22 1998-08-07 Hyaluronsäure-gel, verfahren zur dessen herstellung und hyaluronsäure-gel enthaltendes medizinisches material ATE295745T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP22673497 1997-08-22
JP11756498 1998-04-27
PCT/JP1998/003536 WO1999010385A1 (en) 1997-08-22 1998-08-07 Hyaluronic acid gel, process for producing the same and medical material containing the same

Publications (1)

Publication Number Publication Date
ATE295745T1 true ATE295745T1 (de) 2005-06-15

Family

ID=26455658

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98936706T ATE295745T1 (de) 1997-08-22 1998-08-07 Hyaluronsäure-gel, verfahren zur dessen herstellung und hyaluronsäure-gel enthaltendes medizinisches material

Country Status (11)

Country Link
US (2) US6387413B1 (de)
EP (1) EP1005874B1 (de)
JP (1) JP3359909B2 (de)
KR (1) KR100374666B1 (de)
CN (1) CN1101405C (de)
AT (1) ATE295745T1 (de)
AU (1) AU742675B2 (de)
CA (1) CA2301018C (de)
DE (1) DE69830240T2 (de)
NZ (1) NZ502815A (de)
WO (1) WO1999010385A1 (de)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU742675B2 (en) 1997-08-22 2002-01-10 Denki Kagaku Kogyo Kabushiki Kaisha Hyaluronic acid gel, method of its production and medical material containing it
JP4551563B2 (ja) * 1998-11-10 2010-09-29 電気化学工業株式会社 ヒアルロン酸ゲルの製造方法及び医用材料
KR100730527B1 (ko) * 1999-02-19 2007-06-20 덴끼 가가꾸 고교 가부시키가이샤 히알루론산 겔 조성물과 그의 제조방법 및 그것을함유하는 의용 재료
JP4755795B2 (ja) * 2000-02-03 2011-08-24 電気化学工業株式会社 ヒアルロン酸ゲルの製造方法及びそれを含有する医用材料
JP2001329002A (ja) * 2000-05-25 2001-11-27 Denki Kagaku Kogyo Kk 修飾ヒアルロン酸ゲルとその製造方法及びそれを含有する医用材料
FR2819722B1 (fr) * 2001-01-19 2006-11-24 Corneal Ind Utilisation de l'acide hyaluronique ou d'au moins l'un de ses sels dans le cadre d'un traitemnet chirurgical de la presbytie
JP4990446B2 (ja) * 2001-05-28 2012-08-01 電気化学工業株式会社 関節症治療用注入剤
US7923431B2 (en) 2001-12-21 2011-04-12 Ferrosan Medical Devices A/S Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis
CZ12015U1 (cs) * 2002-01-18 2002-02-25 Cpn Spol. S R.O. Přípravek pro prevenci adheze bandáľe na ránu
JPWO2003084571A1 (ja) * 2002-04-08 2005-08-11 電気化学工業株式会社 骨感染症治療用組成物
EP1507543A4 (de) * 2002-05-09 2006-07-26 Cambridgemed Inc Pharmazeutische zusammensetzung zur behandlung von wunden mit blutplasma oder serum
CN100393322C (zh) * 2002-08-16 2008-06-11 电气化学工业株式会社 分离型医疗材料
US7955288B2 (en) * 2002-12-11 2011-06-07 Ferrosan Medical Devices A/S Gelatine-based materials as swabs
EP1613796B1 (de) 2003-04-10 2017-03-22 Tufts University Konzentrierte wässrige seidenfibroinlösung und deren verwendung
JP4726402B2 (ja) * 2003-06-13 2011-07-20 泰晴 野一色 管腔形成誘導性材料
WO2005000374A1 (ja) * 2003-06-30 2005-01-06 Denki Kagaku Kogyo Kabushiki Kaisha 脊椎・脊髄手術用癒着防止材
CA2554994C (en) * 2004-01-30 2015-05-19 Ferrosan A/S Haemostatic sprays and compositions
US8293890B2 (en) 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
US20050281880A1 (en) * 2004-05-20 2005-12-22 Wei Wang Methods for making injectable polymer hydrogels
KR20070046093A (ko) 2004-07-09 2007-05-02 훼로산 아크티에 셀스카브 히알루론산을 포함하는 지혈 조성물
US20070048391A1 (en) * 2005-08-23 2007-03-01 Cambridgemed, Inc. Composition for reduction of scar formation on wound scar
US7579403B2 (en) * 2006-04-04 2009-08-25 E. I. Du Pont De Nemours And Company Stain resist comprising hyperbranched maleic anhydride-diene polymers
US7579420B2 (en) 2006-04-04 2009-08-25 E. I. Du Pont De Nemours And Company Hyperbranched maleic anhydride-diene polymers
WO2008041514A1 (ja) 2006-09-22 2008-04-10 Kochi University 放射線または抗がん化学療法増感剤
US20100028451A1 (en) 2006-09-26 2010-02-04 Trustees Of Tufts College Silk microspheres for encapsulation and controlled release
WO2009101210A1 (en) * 2008-02-15 2009-08-20 Bone Therapeutics Pharmaceutical composition for use in the treatment or prevention of osteoarticular diseases
KR101784642B1 (ko) 2008-02-15 2017-10-11 본 테라퓨틱스 소시에테아노님 골관절 질환의 치료 및/또는 예방에 사용하기 위한 약학 조성물
CA2716872C (en) 2008-02-29 2015-02-10 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
AU2009288118B2 (en) 2008-09-02 2014-12-11 Allergan, Inc. Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
KR101062068B1 (ko) * 2008-12-01 2011-09-02 포항공과대학교 산학협력단 유착방지용 조성물
JP2011025013A (ja) * 2009-06-25 2011-02-10 Doshisha 癒着防止材及びその製造方法
CN102343110A (zh) * 2010-07-29 2012-02-08 中国科学院化学研究所 消炎促愈合复合功能防粘连载药敷料
JP5730556B2 (ja) * 2010-12-07 2015-06-10 株式会社ブリヂストン ゴムの分析方法
US8398611B2 (en) 2010-12-28 2013-03-19 Depuy Mitek, Inc. Compositions and methods for treating joints
US8455436B2 (en) 2010-12-28 2013-06-04 Depuy Mitek, Llc Compositions and methods for treating joints
JP5461468B2 (ja) * 2011-04-11 2014-04-02 電気化学工業株式会社 ヒアルロン酸ゲルの製造方法及びそれを含有する医用材料
WO2012145652A1 (en) 2011-04-20 2012-10-26 Trustees Of Tufts College Dynamic silk coatings for implantable devices
US8623839B2 (en) * 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
CN104159527B (zh) 2012-03-06 2017-04-12 弗罗桑医疗设备公司 包含止血糊剂的压力容器
JP2015512944A (ja) 2012-04-13 2015-04-30 トラスティーズ・オブ・タフツ・カレッジＴｒｕｓｔｅｅｓ Ｏｆ Ｔｕｆｔｓ Ｃｏｌｌｅｇｅ 絹マイクロスフェアを調製するための方法および組成物
RU2636240C2 (ru) 2012-06-12 2017-11-21 Ферросан Медикал Дивайсиз А/С Сухая гемостатическая композиция
WO2014066884A1 (en) 2012-10-26 2014-05-01 Tufts University Silk-based fabrication techniques to prepare high strength calcium phosphate ceramic scaffolds
TR201905159T4 (tr) 2013-02-15 2019-05-21 Kortuc Inc İntratümöral lokal enjeksiyonda ve taşıyıcı olarak hidrojel ile hidrojen peroksidin kontrollü salımı için kullanılacak radyasyon/kemoterapi sensitizörü.
US10245075B2 (en) * 2013-03-15 2019-04-02 Eurica Califorrniaa Nondestructive means of ectopic pregnancy management
KR101598329B1 (ko) * 2013-03-20 2016-02-29 일동제약주식회사 히알루론산의 제조방법 및 상기 제조방법으로 제조된 히알루론산을 포함하는 유착방지용 조성물
WO2014176458A2 (en) 2013-04-24 2014-10-30 Trustees Of Tufts College Bioresorbable biopolymer anastomosis devices
JP6390873B2 (ja) 2013-06-21 2018-09-19 フェッローサン メディカル ディバイス エー／エス 減圧膨張させた乾燥組成物およびそれを保持するためのシリンジ
EP3017808B1 (de) 2013-07-03 2022-07-13 Ritapharma, Co., Ltd. Wasserlösliches hyaluronsäuregel und verfahren zur herstellung davon
EP3040367A4 (de) * 2013-08-29 2017-04-19 Dainichiseika Color & Chemicals Mfg. Co., Ltd. Verfahren zur herstellung eines wasserunlöslichen formkörpers und wasserunlöslicher formkörper
BR112016013322B1 (pt) 2013-12-11 2020-07-21 Ferrosan Medical Devices A/S métodos para preparação de uma composição seca e para reconstituir uma composição seca, composição seca, uso de uma composição seca, e, kit
WO2015115609A1 (ja) 2014-01-31 2015-08-06 生化学工業株式会社 ジアミン架橋剤、酸性多糖架橋体、及び医用材料
BR112017007466B1 (pt) 2014-10-13 2021-03-02 Ferrosan Medical Devices A/S método para preparar uma composição seca, método para reconstituir a composição seca, pasta, composição seca, recipiente, kit homeostático, e, uso de uma composição seca
KR101521058B1 (ko) 2014-12-08 2015-05-15 이노팜 주식회사 생체적합성 조성물 및 이의 제조방법
US10758645B2 (en) 2014-12-17 2020-09-01 Tufts University Injectable, flexible hydroxyapatite-silk foams for osteochondral and dental repair
RU2705905C2 (ru) 2014-12-24 2019-11-12 Ферросан Медикал Дивайсиз А/С Шприц для удерживания и смешивания первого и второго веществ
US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints
KR101841469B1 (ko) * 2015-01-30 2018-03-23 (주)메디팁 바이오폴리머를 이용한 창상 피복재의 제조방법 및 이를 이용하여 제조된 바이오폴리머를 이용한 창상 피복재
EP3263142A4 (de) * 2015-02-27 2018-10-24 Dainichiseika Color & Chemicals Mfg. Co., Ltd. Medizinisches/kosmetisches material und haftverhinderndes material
JP6298576B2 (ja) * 2015-02-27 2018-03-20 大日精化工業株式会社 医療用材料の製造方法、医療用材料、及び癒着防止材
US20180021477A1 (en) * 2015-02-27 2018-01-25 Dainichiseika Color & Chemicals Mfg. Co., Ltd. Medical material and anti-adhesion material
CA2986981A1 (en) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
CN108601675A (zh) 2015-07-20 2018-09-28 塔夫茨大学 生物可降解的丝质耳管
KR101597794B1 (ko) * 2015-09-22 2016-02-25 바이오플러스 주식회사 겔 시트
WO2017052133A1 (ko) * 2015-09-22 2017-03-30 바이오플러스 주식회사 히알루론산을 이용한 겔 시트 및 그 제조방법
US10864299B2 (en) 2016-04-29 2020-12-15 Trustees Of Tufts College Artificial silk based innervated cornea
WO2018006037A1 (en) 2016-07-01 2018-01-04 Trustees Of Tufts College Innervated artificial skin
US11248313B2 (en) 2016-08-01 2022-02-15 Trustees Of Tufts College Biomimetic mechanical tension driven fabrication of nanofibrillar architecture
CN107029281A (zh) * 2017-04-17 2017-08-11 江苏昌吉永生物科技股份有限公司 一种可吸收止血材料的制备方法
CN107115557B (zh) * 2017-04-17 2019-12-20 江苏昌吉永生物科技股份有限公司 一种医用止血防粘连材料的制备方法
FR3066386B1 (fr) * 2017-05-18 2020-08-28 Bioxis Pharmaceuticals Procede de preparation d'un gel aqueux d'acide hyaluronique
JP6925233B2 (ja) 2017-10-27 2021-08-25 大日精化工業株式会社 化粧料用成形物及びその製造方法
EP4321182A3 (de) 2018-05-09 2024-05-29 Ferrosan Medical Devices A/S Verfahren zur herstellung einer hämostatischen zusammensetzung
CN111001035A (zh) * 2019-12-25 2020-04-14 玉子涛 一种生物活性玻璃复合创面凝胶的制备方法
CN115443292B (zh) * 2020-04-23 2025-02-28 科凝生物制药(深圳)有限公司 生物相容性材料及其制备和使用方法
AU2021292668A1 (en) 2020-06-15 2023-02-09 KORTUC Japan LLC Sensitiser for cancer treatment
TWI840941B (zh) 2022-09-06 2024-05-01 科妍生物科技股份有限公司 製造自體交聯透明質酸凝膠之方法及其產物
CN117281260A (zh) * 2023-11-24 2023-12-26 上海威高医疗技术发展有限公司 一种不含有交联剂的凝胶及其制备方法和应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1086323A (en) 1963-07-18 1967-10-11 Courtaulds Ltd Derivative of carboxy methyl cellulose
DE1577860A1 (de) 1964-10-02 1969-04-17 Metrimpex Magyar Mueszeripari Riss- und Graviermaschine
JPS5111139B2 (de) * 1973-09-20 1976-04-09
EP0010519A1 (de) 1978-10-12 1980-04-30 Battelle Memorial Institute Verfahren zum Vernetzen von Carboxymethylcellulose und durch dieses Verfahren erhaltene Produkte
IT1198449B (it) 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
IT1219587B (it) 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US5143724A (en) * 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
EP0516026A1 (de) 1991-05-28 1992-12-02 Takeda Chemical Industries, Ltd. Hydrogel und Verfahren zu seiner Herstellung
JPH055881A (ja) 1991-06-27 1993-01-14 Sanyo Electric Co Ltd 液晶プロジエクタ
CA2079205C (en) * 1992-09-25 1998-02-10 Rudolf Edgar Falk Use of hyaluronic acid and forms to prevent arterial restenosis
JP3051215B2 (ja) * 1991-08-27 2000-06-12 株式会社資生堂 ヒアルロン酸ゲル及びその製造方法
JP3404557B2 (ja) 1993-09-30 2003-05-12 グンゼ株式会社 架橋ヒアルロン酸及びこれらの複合材料
US5616568A (en) * 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
AU742675B2 (en) 1997-08-22 2002-01-10 Denki Kagaku Kogyo Kabushiki Kaisha Hyaluronic acid gel, method of its production and medical material containing it

Also Published As

Publication number Publication date
CN1267308A (zh) 2000-09-20
AU8561698A (en) 1999-03-16
CA2301018C (en) 2006-06-20
CN1101405C (zh) 2003-02-12
KR100374666B1 (ko) 2003-03-04
EP1005874A4 (de) 2001-02-07
DE69830240D1 (de) 2005-06-23
DE69830240T2 (de) 2005-10-13
NZ502815A (en) 2002-03-01
US6387413B1 (en) 2002-05-14
US6790461B2 (en) 2004-09-14
JP3359909B2 (ja) 2002-12-24
WO1999010385A1 (en) 1999-03-04
EP1005874A1 (de) 2000-06-07
US20020098244A1 (en) 2002-07-25
KR20010023185A (ko) 2001-03-26
EP1005874B1 (de) 2005-05-18
CA2301018A1 (en) 1999-03-04
AU742675B2 (en) 2002-01-10

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