ATE295837T1 - Antagonisten für calciumkanäle vom n-typ zur behandlung von schmerzen - Google Patents
Antagonisten für calciumkanäle vom n-typ zur behandlung von schmerzenInfo
- Publication number
- ATE295837T1 ATE295837T1 AT02760975T AT02760975T ATE295837T1 AT E295837 T1 ATE295837 T1 AT E295837T1 AT 02760975 T AT02760975 T AT 02760975T AT 02760975 T AT02760975 T AT 02760975T AT E295837 T1 ATE295837 T1 AT E295837T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- treatment
- pain
- antagonists
- type calcium
- Prior art date
Links
- 102000004129 N-Type Calcium Channels Human genes 0.000 title 1
- 108090000699 N-Type Calcium Channels Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000010586 diagram Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0102858A SE0102858D0 (sv) | 2001-08-27 | 2001-08-27 | N-type calcium channel antagonists for the treatment of pain |
| PCT/SE2002/001521 WO2003018561A1 (en) | 2001-08-27 | 2002-08-23 | N-type calcium channel antagonists for the treatment of pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE295837T1 true ATE295837T1 (de) | 2005-06-15 |
Family
ID=20285150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02760975T ATE295837T1 (de) | 2001-08-27 | 2002-08-23 | Antagonisten für calciumkanäle vom n-typ zur behandlung von schmerzen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7153865B2 (de) |
| EP (1) | EP1430030B1 (de) |
| JP (1) | JP2005508894A (de) |
| AT (1) | ATE295837T1 (de) |
| DE (1) | DE60204232T2 (de) |
| SE (1) | SE0102858D0 (de) |
| WO (1) | WO2003018561A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003055866A1 (en) * | 2001-12-21 | 2003-07-10 | Bayer Pharmaceuticals Corporation | Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents |
| WO2004080444A2 (en) * | 2003-03-10 | 2004-09-23 | Dynogen Pharmaceuticals, Inc. | Methods for treating lower urinary tract disorders and the related disorders vulvodynia and vulvar vestibulitis using cav2.2 subunit calcium channel modulators |
| CA2518398A1 (en) * | 2003-03-10 | 2004-09-23 | Schering Corporation | Heterocyclic kinase inhibitors: methods of use and synthesis |
| US7223754B2 (en) | 2003-03-10 | 2007-05-29 | Dynogen Pharmaceuticals, Inc. | Thiazolidinone, oxazolidinone, and imidazolone derivatives for treating lower urinary tract and related disorders |
| WO2005000285A2 (en) * | 2003-06-13 | 2005-01-06 | Dynogen Pharmaceuticals, Inc. | METHODS OF TREATING NON-INFLAMMATORY GASTROINTESTINAL TRACT DISORDERS USING Cav2.2 SUBUNIT CALCIUM CHANNEL MODULATORS |
| WO2006058201A2 (en) * | 2004-11-23 | 2006-06-01 | Reddy Us Therapeutics, Inc. | Heterocyclic and bicyclic compounds, compositions and methods |
| EP1963280B1 (de) | 2005-12-22 | 2015-10-28 | Newron Pharmaceuticals S.p.A. | 2-phenylethylaminoderivate als calcium- und/oder natrium-kanalmodulatoren |
| CA2689561C (en) | 2007-06-15 | 2015-11-17 | Newron Pharmaceuticals S.P.A. | Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators |
| EP2496234A1 (de) | 2009-11-07 | 2012-09-12 | Merck Patent GmbH | Heteroarylaminochinoline als tgf-beta-rezeptorkinase-inhibitoren |
| PT2723710T (pt) | 2011-06-27 | 2016-11-14 | Newron Pharm Spa | Derivados fluorados de arilalquilaminocarboxamida |
| WO2014120995A2 (en) * | 2013-02-01 | 2014-08-07 | Wellstat Therapeutics Corporation | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity |
| EA201591746A1 (ru) | 2013-03-14 | 2016-08-31 | КОНВЕРДЖЕН ЭлЭлСи | Способы и композиции для ингибирования бромодомен-содержащих белков |
| JP6882289B2 (ja) | 2015-11-25 | 2021-06-02 | コンバージーン・リミテッド・ライアビリティ・カンパニーConvergene Llc | 二環式betブロモドメイン阻害剤及びその使用 |
| US10889566B2 (en) * | 2017-08-29 | 2021-01-12 | Chulabhorn Foundation | Derivatives and composition of quinoline and naphthyridine |
| WO2020219168A1 (en) | 2019-04-24 | 2020-10-29 | Convergene, Llc | Small molecule bromodomain inhibitors and uses thereof |
| WO2023081800A1 (en) * | 2021-11-05 | 2023-05-11 | The Regents Of The University Of California | Alpha-2a adrenergic receptor modulators and uses thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1573186A (en) * | 1977-09-14 | 1980-08-20 | Wyeth John & Brother Ltd | 4-aminoquinoline derivatives |
| WO2000064877A1 (en) | 1999-04-26 | 2000-11-02 | Neurogen Corporation | 2-aminoquinolinecarboxamides: neurokinin receptor ligands |
-
2001
- 2001-08-27 SE SE0102858A patent/SE0102858D0/xx unknown
-
2002
- 2002-08-23 JP JP2003523224A patent/JP2005508894A/ja active Pending
- 2002-08-23 WO PCT/SE2002/001521 patent/WO2003018561A1/en not_active Ceased
- 2002-08-23 US US10/488,025 patent/US7153865B2/en not_active Expired - Fee Related
- 2002-08-23 AT AT02760975T patent/ATE295837T1/de not_active IP Right Cessation
- 2002-08-23 DE DE60204232T patent/DE60204232T2/de not_active Expired - Fee Related
- 2002-08-23 EP EP02760975A patent/EP1430030B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005508894A (ja) | 2005-04-07 |
| EP1430030B1 (de) | 2005-05-18 |
| WO2003018561A1 (en) | 2003-03-06 |
| SE0102858D0 (sv) | 2001-08-27 |
| US7153865B2 (en) | 2006-12-26 |
| US20050131020A1 (en) | 2005-06-16 |
| DE60204232T2 (de) | 2006-01-26 |
| DE60204232D1 (de) | 2005-06-23 |
| EP1430030A1 (de) | 2004-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |