ATE296839T1 - Antikörper zur krebsbehandlung und -diagnose - Google Patents
Antikörper zur krebsbehandlung und -diagnoseInfo
- Publication number
- ATE296839T1 ATE296839T1 AT00912115T AT00912115T ATE296839T1 AT E296839 T1 ATE296839 T1 AT E296839T1 AT 00912115 T AT00912115 T AT 00912115T AT 00912115 T AT00912115 T AT 00912115T AT E296839 T1 ATE296839 T1 AT E296839T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- application
- diagnosis
- daf
- directed against
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12226299P | 1999-03-01 | 1999-03-01 | |
| PCT/US2000/005352 WO2000052054A2 (en) | 1999-03-01 | 2000-02-29 | Antibodies for cancer therapy and diagnosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE296839T1 true ATE296839T1 (de) | 2005-06-15 |
Family
ID=22401661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00912115T ATE296839T1 (de) | 1999-03-01 | 2000-02-29 | Antikörper zur krebsbehandlung und -diagnose |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7288249B2 (de) |
| EP (1) | EP1157041B1 (de) |
| JP (1) | JP2002543044A (de) |
| AT (1) | ATE296839T1 (de) |
| AU (1) | AU770952B2 (de) |
| CA (1) | CA2361877A1 (de) |
| DE (1) | DE60020529T2 (de) |
| ES (1) | ES2243240T3 (de) |
| IL (2) | IL144559A0 (de) |
| PT (1) | PT1157041E (de) |
| WO (1) | WO2000052054A2 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030180290A1 (en) * | 1995-06-07 | 2003-09-25 | Idec Pharmaceuticals Corporation | Anti-CD80 antibody having ADCC activity for ADCC mediated killing of B cell lymphoma cells alone or in combination with other therapies |
| EP1157041B1 (de) | 1999-03-01 | 2005-06-01 | Genentech, Inc. | Antikörper zur krebsbehandlung und -diagnose |
| SE0000597D0 (sv) * | 2000-02-24 | 2000-02-24 | Active Biotech Ab | Novel antibody |
| US7097840B2 (en) * | 2000-03-16 | 2006-08-29 | Genentech, Inc. | Methods of treatment using anti-ErbB antibody-maytansinoid conjugates |
| US20020115065A1 (en) * | 2000-08-28 | 2002-08-22 | Ton Logtenberg | Differentially expressed epitopes and uses thereof |
| CA2421751C (en) * | 2000-09-11 | 2014-02-11 | Donald W. Kufe | Muc1 extracellular domain and cancer treatment compositions and methods derived therefrom |
| US7611711B2 (en) | 2001-01-17 | 2009-11-03 | Vegenics Limited | VEGFR-3 inhibitor materials and methods |
| US20030103971A1 (en) * | 2001-11-09 | 2003-06-05 | Kandasamy Hariharan | Immunoregulatory antibodies and uses thereof |
| CA2436180C (en) * | 2001-01-31 | 2011-11-08 | Idec Pharmaceutical Corporation | Immunoregulatory antibodies and uses thereof |
| US7189800B2 (en) | 2001-03-27 | 2007-03-13 | Samuel Bogoch | Replikin peptides in rapid replication of glioma cells and in influenza epidemics |
| US7774144B2 (en) | 2001-10-26 | 2010-08-10 | Samuel Bogoch | System and method for identifying complex patterns of amino acids |
| NZ592340A (en) | 2001-03-27 | 2012-12-21 | Elenore S Bogoch | A method for making a virus vaccine compising Replikin peptides |
| EP1270732A1 (de) * | 2001-06-21 | 2003-01-02 | Schuler, Gerold | Transfektion von eukaryotischen Zellen mit linearen Polynukleotiden mittels Elektroporation |
| IL160659A0 (en) * | 2001-09-05 | 2004-08-31 | Genentech Inc | Methods for the identification of polypeptide antigens associated with disorders involving aberrant cell proliferation and compositions useful for the treatment of such disorders |
| ES2288900T3 (es) * | 2001-10-05 | 2008-02-01 | Affimed Therapeutics Ag | Anticuerpo de origen humano para inhibir la agregacion de trombocitos. |
| US8455627B2 (en) * | 2001-10-05 | 2013-06-04 | Affimed Therapeutics, Ag | Human antibody specific for activated state of platelet integrin receptor GPIIb/IIIa |
| US8435529B2 (en) | 2002-06-14 | 2013-05-07 | Immunomedics, Inc. | Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy |
| US9745380B2 (en) * | 2002-03-01 | 2017-08-29 | Immunomedics, Inc. | RS7 antibodies |
| CA2478047C (en) | 2002-03-01 | 2014-01-21 | Immunomedics, Inc. | Rs7 antibodies |
| US9770517B2 (en) * | 2002-03-01 | 2017-09-26 | Immunomedics, Inc. | Anti-Trop-2 antibody-drug conjugates and uses thereof |
| WO2004013180A2 (en) * | 2002-08-01 | 2004-02-12 | Immunomedics, Inc. | Alpha-fetoprotein immu31 antibodies and fusion proteins and methods of use thereof |
| GB2392723B (en) * | 2002-09-04 | 2005-01-12 | Bioinvent Int Ab | Screening methods |
| GB0227644D0 (en) * | 2002-11-27 | 2003-01-08 | Cancer Rec Tech Ltd | Specific binding members and uses thereof |
| US8088387B2 (en) | 2003-10-10 | 2012-01-03 | Immunogen Inc. | Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates |
| US8494781B2 (en) | 2003-06-06 | 2013-07-23 | Samuel Bogoch | Systems and methods for identifying replikin scaffolds and uses of said replikin scaffolds |
| AU2004293502B2 (en) * | 2003-11-28 | 2010-12-02 | National Research Council Of Canada | Anticarcinoma antibodies and uses thereof |
| EP1749538A4 (de) * | 2004-03-31 | 2009-11-11 | Kirin Pharma Kk | Verfahren zur auslösung der differenzierung von regulatorischen t-zellen und ihrer proliferation mit gpi-anker-protein-agonisten und medizinische zusammensetzung dafür |
| US9254315B2 (en) | 2004-04-28 | 2016-02-09 | Samuel Bogoch | Systems and methods for identifying replikin scaffolds and uses of said replikin scaffolds |
| EP1623996A1 (de) * | 2004-08-06 | 2006-02-08 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Verbessertes Verfahren zur Auswahl eines Proteins von einer Bibliothek |
| WO2006049498A1 (en) * | 2004-11-05 | 2006-05-11 | Modiquest B.V. | Means and methods for isolating and/or identifying a target molecule |
| US20050181479A1 (en) * | 2005-03-04 | 2005-08-18 | Medimmune, Inc. | Periplasmic expression of antibodies using a single signal sequence |
| WO2006117782A2 (en) * | 2005-05-04 | 2006-11-09 | Quark Pharmaceuticals, Inc. | Recombinant antibodies against cd55 and cd59 and uses thereof |
| US8211648B2 (en) * | 2005-07-22 | 2012-07-03 | Kalobios Pharmaceuticals, Inc. | Secretion of antibodies without signal peptides from bacteria |
| WO2007033167A2 (en) * | 2005-09-12 | 2007-03-22 | The Regents Of The University Of Michigan | Compositions and methods for detecting and treating cancer |
| TW200812615A (en) | 2006-03-22 | 2008-03-16 | Hoffmann La Roche | Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2 |
| WO2008156914A2 (en) | 2007-05-30 | 2008-12-24 | Samuel Bogoch | Synthetic replikin peptides against pathogenic infection of invertebrates in aquaculture |
| ES2672769T3 (es) | 2007-08-29 | 2018-06-18 | Sanofi | Anticuerpos anti-CXCR5 humanizados, derivados de los mismos y sus usos |
| AU2013203265B2 (en) * | 2007-08-29 | 2016-06-23 | Sanofi | Humanized anti-CXCR5 antibodies, derivatives thereof and their uses |
| US8541183B2 (en) | 2007-09-11 | 2013-09-24 | Cancer Prevention And Cure, Ltd. | Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof |
| EP2088432A1 (de) * | 2008-02-11 | 2009-08-12 | MorphoSys AG | Verfahren zur Identifikation eines Antikörpers oder eines Targets |
| US9233148B2 (en) | 2009-01-09 | 2016-01-12 | Samuel Bogoch | Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza |
| ES2703714T3 (es) | 2009-03-12 | 2019-03-12 | Cancer Prevention & Cure Ltd | Métodos de identificación, evaluación, prevención y terapia de enfermedades pulmonares y kits de los mismos, incluida la identificación, evaluación, prevención y terapia de enfermedades en base al género |
| NZ596603A (en) | 2009-05-29 | 2013-07-26 | Morphosys Ag | A collection of antibodies or fragments having properties relevant to developability |
| US9320784B2 (en) | 2009-08-07 | 2016-04-26 | Samuel Bogoch | Peptides shared among lethal cancers and therapeutic compositions comprising said peptides |
| SG189950A1 (en) | 2010-11-19 | 2013-06-28 | Morphosys Ag | A collection and methods for its use |
| EP2702411A4 (de) | 2011-04-29 | 2015-07-22 | Cancer Prevention & Cure Ltd | Verfahren zur identifikation und diagnose von lungenkrankheiten mithilfe von klassifizierungssystemen und kits dafür |
| GB201116364D0 (en) | 2011-09-22 | 2011-11-02 | Bioinvent Int Ab | Screening methods and uses thereof |
| US9592289B2 (en) | 2012-03-26 | 2017-03-14 | Sanofi | Stable IgG4 based binding agent formulations |
| US9382329B2 (en) | 2012-08-14 | 2016-07-05 | Ibc Pharmaceuticals, Inc. | Disease therapy by inducing immune response to Trop-2 expressing cells |
| US9797907B2 (en) | 2015-04-22 | 2017-10-24 | Immunomedics, Inc. | Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells |
| KR101875912B1 (ko) * | 2016-10-13 | 2018-07-06 | 한국원자력연구원 | 암 표적 치료를 위한 방사성 동위원소가 표지된 cd55 표적 항체 및 이의 용도 |
| CN110709936A (zh) | 2017-04-04 | 2020-01-17 | 肺癌蛋白质组学有限责任公司 | 用于早期肺癌预后的基于血浆的蛋白质概况分析 |
| US20220088193A1 (en) * | 2019-02-20 | 2022-03-24 | Agonox, Inc. | Anti-CD55 Antibodies and Related Compositions and Methods |
| CN116646088B (zh) * | 2023-07-27 | 2023-12-01 | 广东省人民医院 | 一种预测方法、装置、设备及介质 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS63500797A (ja) * | 1985-05-24 | 1988-03-24 | ニユ−ヨ−ク ユニバ−シイテイ | 崩壊加速因子に対するモノクロ−ン抗体、その生成方法および使用 |
| US5374548A (en) | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
| ATE130764T1 (de) | 1988-10-17 | 1995-12-15 | Cancer Res Campaign Tech | Anti-idiotyp antikörper induktion eines antitumorenresponses. |
| ES2136092T3 (es) | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
| US5733743A (en) | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| WO1994026787A1 (en) | 1993-05-07 | 1994-11-24 | The Board Of Trustees Of The Leland Stanford Junior University | Method for generating cell type specific phage antibody libraries |
| WO1995015982A2 (en) | 1993-12-08 | 1995-06-15 | Genzyme Corporation | Process for generating specific antibodies |
| JP3562834B2 (ja) | 1994-06-01 | 2004-09-08 | 孝夫 辻 | 便中daf分子の検査方法 |
| WO1997002479A2 (en) | 1995-06-30 | 1997-01-23 | Yale University | Human monoclonal anti-tumor antibodies |
| PT1516628E (pt) | 1995-07-27 | 2013-09-24 | Genentech Inc | Formulação de proteína liofilizada isotónica estável |
| DK0934526T3 (da) | 1996-10-08 | 2003-05-05 | Bisys B V U | Fremgangsmåder og midler til udvælgelse af peptider og proteiner, der har specifik affinitet til et mål |
| US5985543A (en) | 1996-10-11 | 1999-11-16 | The Trustees Of The University Of Pennsylvania | Compositions and methods for detection of antibody binding to cells |
| AU6451998A (en) | 1997-03-06 | 1998-09-22 | Bard Diagnostic Sciences, Inc. | Screening and treatment using complement regulator or receptor proteins |
| DK0979281T3 (da) * | 1997-05-02 | 2005-11-21 | Genentech Inc | Fremgangsmåde til fremstilling af multispecifikke antistoffer med heteromultimere og fælles bestanddele |
| GB9804065D0 (en) * | 1998-02-26 | 1998-04-22 | Cancer Res Campaign Tech | Tumour associated antigen 791Tgp72 |
| US6794128B2 (en) | 1998-04-24 | 2004-09-21 | The Regents Of The University Of California | Methods of selecting internalizing antibodies |
| EP1157041B1 (de) | 1999-03-01 | 2005-06-01 | Genentech, Inc. | Antikörper zur krebsbehandlung und -diagnose |
| US20030129677A1 (en) * | 2000-05-12 | 2003-07-10 | Martens Mark G. | Diagnostic method for screening complement regulatory protein levels |
| WO2007033167A2 (en) * | 2005-09-12 | 2007-03-22 | The Regents Of The University Of Michigan | Compositions and methods for detecting and treating cancer |
-
2000
- 2000-02-29 EP EP00912115A patent/EP1157041B1/de not_active Revoked
- 2000-02-29 JP JP2000602278A patent/JP2002543044A/ja not_active Withdrawn
- 2000-02-29 ES ES00912115T patent/ES2243240T3/es not_active Expired - Lifetime
- 2000-02-29 PT PT00912115T patent/PT1157041E/pt unknown
- 2000-02-29 AT AT00912115T patent/ATE296839T1/de not_active IP Right Cessation
- 2000-02-29 AU AU33898/00A patent/AU770952B2/en not_active Expired
- 2000-02-29 CA CA002361877A patent/CA2361877A1/en not_active Abandoned
- 2000-02-29 DE DE60020529T patent/DE60020529T2/de not_active Revoked
- 2000-02-29 IL IL14455900A patent/IL144559A0/xx active IP Right Grant
- 2000-02-29 WO PCT/US2000/005352 patent/WO2000052054A2/en not_active Ceased
-
2001
- 2001-07-25 IL IL144559A patent/IL144559A/en not_active IP Right Cessation
-
2003
- 2003-05-28 US US10/447,331 patent/US7288249B2/en not_active Expired - Lifetime
-
2007
- 2007-06-19 US US11/765,336 patent/US20080166698A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000052054A3 (en) | 2001-08-23 |
| EP1157041B1 (de) | 2005-06-01 |
| EP1157041A2 (de) | 2001-11-28 |
| JP2002543044A (ja) | 2002-12-17 |
| AU3389800A (en) | 2000-09-21 |
| DE60020529D1 (de) | 2005-07-07 |
| WO2000052054A2 (en) | 2000-09-08 |
| CA2361877A1 (en) | 2000-09-08 |
| AU770952B2 (en) | 2004-03-11 |
| PT1157041E (pt) | 2005-10-31 |
| US7288249B2 (en) | 2007-10-30 |
| US20080166698A1 (en) | 2008-07-10 |
| DE60020529T2 (de) | 2006-04-27 |
| IL144559A0 (en) | 2002-05-23 |
| IL144559A (en) | 2006-12-10 |
| US20030219434A1 (en) | 2003-11-27 |
| ES2243240T3 (es) | 2005-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1157041 Country of ref document: EP |
|
| RZN | Patent revoked |