ATE296839T1 - Antikörper zur krebsbehandlung und -diagnose - Google Patents
Antikörper zur krebsbehandlung und -diagnoseInfo
- Publication number
- ATE296839T1 ATE296839T1 AT00912115T AT00912115T ATE296839T1 AT E296839 T1 ATE296839 T1 AT E296839T1 AT 00912115 T AT00912115 T AT 00912115T AT 00912115 T AT00912115 T AT 00912115T AT E296839 T1 ATE296839 T1 AT E296839T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- application
- diagnosis
- daf
- directed against
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12226299P | 1999-03-01 | 1999-03-01 | |
| PCT/US2000/005352 WO2000052054A2 (en) | 1999-03-01 | 2000-02-29 | Antibodies for cancer therapy and diagnosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE296839T1 true ATE296839T1 (de) | 2005-06-15 |
Family
ID=22401661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00912115T ATE296839T1 (de) | 1999-03-01 | 2000-02-29 | Antikörper zur krebsbehandlung und -diagnose |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7288249B2 (de) |
| EP (1) | EP1157041B1 (de) |
| JP (1) | JP2002543044A (de) |
| AT (1) | ATE296839T1 (de) |
| AU (1) | AU770952B2 (de) |
| CA (1) | CA2361877A1 (de) |
| DE (1) | DE60020529T2 (de) |
| ES (1) | ES2243240T3 (de) |
| IL (2) | IL144559A0 (de) |
| PT (1) | PT1157041E (de) |
| WO (1) | WO2000052054A2 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030180290A1 (en) * | 1995-06-07 | 2003-09-25 | Idec Pharmaceuticals Corporation | Anti-CD80 antibody having ADCC activity for ADCC mediated killing of B cell lymphoma cells alone or in combination with other therapies |
| IL144559A0 (en) | 1999-03-01 | 2002-05-23 | Genentech Inc | Antibodies for cancer therapy and diagnosis |
| SE0000597D0 (sv) * | 2000-02-24 | 2000-02-24 | Active Biotech Ab | Novel antibody |
| US7097840B2 (en) * | 2000-03-16 | 2006-08-29 | Genentech, Inc. | Methods of treatment using anti-ErbB antibody-maytansinoid conjugates |
| US20020115065A1 (en) * | 2000-08-28 | 2002-08-22 | Ton Logtenberg | Differentially expressed epitopes and uses thereof |
| JP5165175B2 (ja) * | 2000-09-11 | 2013-03-21 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | Muc1細胞外ドメインおよびそれから得られた癌治療組成物 |
| US7611711B2 (en) | 2001-01-17 | 2009-11-03 | Vegenics Limited | VEGFR-3 inhibitor materials and methods |
| CN100574803C (zh) * | 2001-01-31 | 2009-12-30 | 拜奥根Idec公司 | 免疫调节抗体在治疗肿瘤性疾病中的用途 |
| US20030103971A1 (en) * | 2001-11-09 | 2003-06-05 | Kandasamy Hariharan | Immunoregulatory antibodies and uses thereof |
| KR100906102B1 (ko) | 2001-03-27 | 2009-07-07 | 사무엘 보고치 | 레플리킨 펩타이드 및 그의 이용 |
| US7189800B2 (en) | 2001-03-27 | 2007-03-13 | Samuel Bogoch | Replikin peptides in rapid replication of glioma cells and in influenza epidemics |
| US7774144B2 (en) | 2001-10-26 | 2010-08-10 | Samuel Bogoch | System and method for identifying complex patterns of amino acids |
| EP1270732A1 (de) * | 2001-06-21 | 2003-01-02 | Schuler, Gerold | Transfektion von eukaryotischen Zellen mit linearen Polynukleotiden mittels Elektroporation |
| NZ531515A (en) * | 2001-09-05 | 2007-11-30 | Genentech Inc | Methods for the identification of polypeptide antigens associated with disorders involving aberrant cell proliferation and compositions useful for the treatment of such disorders |
| ES2288900T3 (es) * | 2001-10-05 | 2008-02-01 | Affimed Therapeutics Ag | Anticuerpo de origen humano para inhibir la agregacion de trombocitos. |
| US8455627B2 (en) * | 2001-10-05 | 2013-06-04 | Affimed Therapeutics, Ag | Human antibody specific for activated state of platelet integrin receptor GPIIb/IIIa |
| US8435529B2 (en) | 2002-06-14 | 2013-05-07 | Immunomedics, Inc. | Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy |
| US9770517B2 (en) * | 2002-03-01 | 2017-09-26 | Immunomedics, Inc. | Anti-Trop-2 antibody-drug conjugates and uses thereof |
| US9745380B2 (en) * | 2002-03-01 | 2017-08-29 | Immunomedics, Inc. | RS7 antibodies |
| CA2478047C (en) * | 2002-03-01 | 2014-01-21 | Immunomedics, Inc. | Rs7 antibodies |
| JP5138867B2 (ja) * | 2002-08-01 | 2013-02-06 | イミューノメディクス、インコーポレイテッド | α−フェトタンパク質Immu31抗体および融合タンパク質ならびにその使用方法 |
| GB2392723B (en) * | 2002-09-04 | 2005-01-12 | Bioinvent Int Ab | Screening methods |
| GB0227644D0 (en) * | 2002-11-27 | 2003-01-08 | Cancer Rec Tech Ltd | Specific binding members and uses thereof |
| US8088387B2 (en) | 2003-10-10 | 2012-01-03 | Immunogen Inc. | Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates |
| US8494781B2 (en) | 2003-06-06 | 2013-07-23 | Samuel Bogoch | Systems and methods for identifying replikin scaffolds and uses of said replikin scaffolds |
| EP1694845B8 (de) * | 2003-11-28 | 2017-12-20 | National Research Council of Canada | Antikarzinom-antikörper und verwendungen davon |
| EP1749538A4 (de) * | 2004-03-31 | 2009-11-11 | Kirin Pharma Kk | Verfahren zur auslösung der differenzierung von regulatorischen t-zellen und ihrer proliferation mit gpi-anker-protein-agonisten und medizinische zusammensetzung dafür |
| US9254315B2 (en) | 2004-04-28 | 2016-02-09 | Samuel Bogoch | Systems and methods for identifying replikin scaffolds and uses of said replikin scaffolds |
| EP1623996A1 (de) * | 2004-08-06 | 2006-02-08 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Verbessertes Verfahren zur Auswahl eines Proteins von einer Bibliothek |
| WO2006049498A1 (en) * | 2004-11-05 | 2006-05-11 | Modiquest B.V. | Means and methods for isolating and/or identifying a target molecule |
| US20050181479A1 (en) * | 2005-03-04 | 2005-08-18 | Medimmune, Inc. | Periplasmic expression of antibodies using a single signal sequence |
| EP1885396A2 (de) * | 2005-05-04 | 2008-02-13 | Quark Pharmaceuticals, Inc. | Rekombinante antikörper gegen cd55 und cd59 und ihre verwendungen |
| US8211648B2 (en) * | 2005-07-22 | 2012-07-03 | Kalobios Pharmaceuticals, Inc. | Secretion of antibodies without signal peptides from bacteria |
| WO2007033167A2 (en) * | 2005-09-12 | 2007-03-22 | The Regents Of The University Of Michigan | Compositions and methods for detecting and treating cancer |
| TW200812615A (en) | 2006-03-22 | 2008-03-16 | Hoffmann La Roche | Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2 |
| JP5675348B2 (ja) | 2007-05-30 | 2015-02-25 | ボゴーク,サミュエル | 水産養殖における無脊椎動物の病原性感染に対する合成レプリキンペプチド |
| MX338397B (es) | 2007-08-29 | 2016-04-15 | Sanofi Aventis | Anticuerpos anti - cxcr5 humanizados, derivados de los mismos y su uso. |
| AU2013203261B2 (en) * | 2007-08-29 | 2016-07-14 | Sanofi | Humanized anti-cxcr5 antibodies, derivatives thereof and their use |
| US8541183B2 (en) | 2007-09-11 | 2013-09-24 | Cancer Prevention And Cure, Ltd. | Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof |
| EP2088432A1 (de) | 2008-02-11 | 2009-08-12 | MorphoSys AG | Verfahren zur Identifikation eines Antikörpers oder eines Targets |
| US9233148B2 (en) | 2009-01-09 | 2016-01-12 | Samuel Bogoch | Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza |
| CN108181457B (zh) | 2009-03-12 | 2021-03-30 | 癌症预防和治疗有限公司 | 鉴定、评估、预防以及治疗肺疾病的方法及试剂盒 |
| CA2758356C (en) | 2009-05-29 | 2016-07-26 | Morphosys Ag | A collection of vh and vl pairs having favourable biophysical properties and methods for its use |
| US8367586B2 (en) | 2010-11-19 | 2013-02-05 | Morphosys Ag | Collection and methods for its use |
| AU2012249288C1 (en) | 2011-04-29 | 2017-12-21 | Lung Cancer Proteomics Llc | Methods of identification and diagnosis of lung diseases using classification systems and kits thereof |
| WO2013013075A2 (en) | 2011-07-20 | 2013-01-24 | Samuel Bogoch | Peptides shared among lethal cancers and therapeutic compositions comprising said peptides |
| GB201116364D0 (en) | 2011-09-22 | 2011-11-02 | Bioinvent Int Ab | Screening methods and uses thereof |
| US9592289B2 (en) | 2012-03-26 | 2017-03-14 | Sanofi | Stable IgG4 based binding agent formulations |
| US9382329B2 (en) | 2012-08-14 | 2016-07-05 | Ibc Pharmaceuticals, Inc. | Disease therapy by inducing immune response to Trop-2 expressing cells |
| AU2016252771B2 (en) | 2015-04-22 | 2021-12-16 | Immunomedics, Inc. | Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells |
| KR101875912B1 (ko) * | 2016-10-13 | 2018-07-06 | 한국원자력연구원 | 암 표적 치료를 위한 방사성 동위원소가 표지된 cd55 표적 항체 및 이의 용도 |
| CN110709936A (zh) | 2017-04-04 | 2020-01-17 | 肺癌蛋白质组学有限责任公司 | 用于早期肺癌预后的基于血浆的蛋白质概况分析 |
| CN113660945A (zh) * | 2019-02-20 | 2021-11-16 | 艾根奥克思公司 | 抗cd55抗体和相关组合物和方法 |
| CN116646088B (zh) * | 2023-07-27 | 2023-12-01 | 广东省人民医院 | 一种预测方法、装置、设备及介质 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| EP0223842A4 (de) * | 1985-05-24 | 1987-08-24 | Univ New York | Monoklonaler antikörper gegen zerfallakzelerationsfaktor, dessen herstellung und verwendung. |
| US5374548A (en) * | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
| JP3095169B2 (ja) | 1988-10-17 | 2000-10-03 | キャンサー リサーチ キャンペーン テクノロジー リミティド | 抗イディオタイプ抗体による抗腫瘍応答の誘導 |
| US5565332A (en) * | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| US5733743A (en) * | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| WO1994026787A1 (en) | 1993-05-07 | 1994-11-24 | The Board Of Trustees Of The Leland Stanford Junior University | Method for generating cell type specific phage antibody libraries |
| WO1995015982A2 (en) | 1993-12-08 | 1995-06-15 | Genzyme Corporation | Process for generating specific antibodies |
| JP3562834B2 (ja) * | 1994-06-01 | 2004-09-08 | 孝夫 辻 | 便中daf分子の検査方法 |
| WO1997002479A2 (en) | 1995-06-30 | 1997-01-23 | Yale University | Human monoclonal anti-tumor antibodies |
| ES2434840T3 (es) | 1995-07-27 | 2013-12-17 | Genentech, Inc. | Formulación de proteína liofilizada isotónica estable |
| DK0934526T3 (da) | 1996-10-08 | 2003-05-05 | Bisys B V U | Fremgangsmåder og midler til udvælgelse af peptider og proteiner, der har specifik affinitet til et mål |
| US5985543A (en) | 1996-10-11 | 1999-11-16 | The Trustees Of The University Of Pennsylvania | Compositions and methods for detection of antibody binding to cells |
| JP2001515589A (ja) | 1997-03-06 | 2001-09-18 | バイオン ダイアグノスティック サイエンシーズ,インコーポレイテッド | 補体レギュレーターまたはレセプタータンパク質を使用するスクリーニングおよび処置 |
| ATE299938T1 (de) * | 1997-05-02 | 2005-08-15 | Genentech Inc | Ein verfahren zur herstellung multispezifischer antikörper die heteromultimere und gemeinsame komponenten besitzen |
| GB9804065D0 (en) * | 1998-02-26 | 1998-04-22 | Cancer Res Campaign Tech | Tumour associated antigen 791Tgp72 |
| US6794128B2 (en) | 1998-04-24 | 2004-09-21 | The Regents Of The University Of California | Methods of selecting internalizing antibodies |
| IL144559A0 (en) | 1999-03-01 | 2002-05-23 | Genentech Inc | Antibodies for cancer therapy and diagnosis |
| US20030129677A1 (en) * | 2000-05-12 | 2003-07-10 | Martens Mark G. | Diagnostic method for screening complement regulatory protein levels |
| WO2007033167A2 (en) * | 2005-09-12 | 2007-03-22 | The Regents Of The University Of Michigan | Compositions and methods for detecting and treating cancer |
-
2000
- 2000-02-29 IL IL14455900A patent/IL144559A0/xx active IP Right Grant
- 2000-02-29 JP JP2000602278A patent/JP2002543044A/ja not_active Withdrawn
- 2000-02-29 AT AT00912115T patent/ATE296839T1/de not_active IP Right Cessation
- 2000-02-29 DE DE60020529T patent/DE60020529T2/de not_active Revoked
- 2000-02-29 AU AU33898/00A patent/AU770952B2/en not_active Expired
- 2000-02-29 WO PCT/US2000/005352 patent/WO2000052054A2/en not_active Ceased
- 2000-02-29 EP EP00912115A patent/EP1157041B1/de not_active Revoked
- 2000-02-29 CA CA002361877A patent/CA2361877A1/en not_active Abandoned
- 2000-02-29 ES ES00912115T patent/ES2243240T3/es not_active Expired - Lifetime
- 2000-02-29 PT PT00912115T patent/PT1157041E/pt unknown
-
2001
- 2001-07-25 IL IL144559A patent/IL144559A/en not_active IP Right Cessation
-
2003
- 2003-05-28 US US10/447,331 patent/US7288249B2/en not_active Expired - Lifetime
-
2007
- 2007-06-19 US US11/765,336 patent/US20080166698A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60020529T2 (de) | 2006-04-27 |
| AU3389800A (en) | 2000-09-21 |
| DE60020529D1 (de) | 2005-07-07 |
| US20080166698A1 (en) | 2008-07-10 |
| IL144559A (en) | 2006-12-10 |
| US7288249B2 (en) | 2007-10-30 |
| ES2243240T3 (es) | 2005-12-01 |
| EP1157041A2 (de) | 2001-11-28 |
| PT1157041E (pt) | 2005-10-31 |
| CA2361877A1 (en) | 2000-09-08 |
| US20030219434A1 (en) | 2003-11-27 |
| AU770952B2 (en) | 2004-03-11 |
| WO2000052054A2 (en) | 2000-09-08 |
| WO2000052054A3 (en) | 2001-08-23 |
| EP1157041B1 (de) | 2005-06-01 |
| IL144559A0 (en) | 2002-05-23 |
| JP2002543044A (ja) | 2002-12-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1157041 Country of ref document: EP |
|
| RZN | Patent revoked |