ATE29717T1 - 4',8-bis-hydrogensulfate von fenoldopam. - Google Patents

4',8-bis-hydrogensulfate von fenoldopam.

Info

Publication number: ATE29717T1
Authority: AT; Austria
Prior art keywords: fenoldopam; bis; hydrogen sulfate; saltsthereof; prodrugs
Prior art date: 1984-04-26

Application number

AT85302892T

Other languages

English (en)

Inventor

Dimitri Eustrati Gaitanopoulos

Joseph Weinstock

Original Assignee

Smithkline Beckman Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-04-26

Filing date

1985-04-25

Publication date

1987-10-15

1985-04-25 Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp

1987-10-15 Application granted granted Critical

1987-10-15 Publication of ATE29717T1 publication Critical patent/ATE29717T1/de

Links

TVURRHSHRRELCG-UHFFFAOYSA-N fenoldopam Chemical compound C1=CC(O)=CC=C1C1C2=CC(O)=C(O)C(Cl)=C2CCNC1 TVURRHSHRRELCG-UHFFFAOYSA-N 0.000 title abstract 3
229960002724 fenoldopam Drugs 0.000 title abstract 3
KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical class [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 abstract 1
230000003291 dopaminomimetic effect Effects 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Other In-Based Heterocyclic Compounds (AREA)

AT85302892T 1984-04-26 1985-04-25 4',8-bis-hydrogensulfate von fenoldopam. ATE29717T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/604,101 US4600714A (en)	1984-04-26	1984-04-26	Fenoldopam 4',8-bis-hydrogen sulfate and dopaminergic use thereof
EP85302892A EP0160513B1 (de)	1984-04-26	1985-04-25	4',8-Bis-hydrogensulfate von Fenoldopam

Publications (1)

Publication Number	Publication Date
ATE29717T1 true ATE29717T1 (de)	1987-10-15

Family

ID=24418182

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85302892T ATE29717T1 (de)	1984-04-26	1985-04-25	4',8-bis-hydrogensulfate von fenoldopam.

Country Status (11)

Country	Link
US (1)	US4600714A (de)
EP (1)	EP0160513B1 (de)
JP (1)	JPS60233059A (de)
AT (1)	ATE29717T1 (de)
AU (1)	AU582575B2 (de)
CA (1)	CA1248098A (de)
DE (1)	DE3560633D1 (de)
DK (1)	DK184685A (de)
ES (1)	ES8604883A1 (de)
PT (1)	PT80351B (de)
ZA (1)	ZA852983B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5843984A (en) *	1996-05-09	1998-12-01	Eli Lilly And Company	Sulfated benzothiophene derivatives, methods of use and formulations containing same
RU2326870C2 (ru) *	2003-08-04	2008-06-20	Валерий Хажмуратович ЖИЛОВ	Применение циклических биоизостеров производных пуриновой системы для лечения расстройств, вызванных нарушениями нитрергической и дофаминергической систем
EP1655301B1 (de)	2003-08-04	2015-03-11	Valery Khazhmuratovich Zhilov	Cyclische bioisostere von purinsystemderivaten und darauf basierende pharmazeutische zusammensetzung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4197297A (en) *	1976-11-17	1980-04-08	Smithkline Corporation	6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines
US4104379A (en) *	1977-01-19	1978-08-01	Smithkline Corporation	Substituted 1-alkylthiophenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
EP0022330B1 (de) *	1979-07-10	1983-12-21	Smithkline Beckman Corporation	Synergistische blutdrucksenkende Zusammensetzungen
US4388240A (en) *	1982-01-06	1983-06-14	Smithkline Beckman Corporation	6-Chloro-7,8-dihydroxy-1-(p-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine sulfate esters
NZ203064A (en) *	1982-02-24	1985-05-31	Smithkline Beckman Corp	R-or s-6-chloro-7,8-dihydroxy-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1h-3-benzazepine
US4514394A (en) *	1983-05-25	1985-04-30	Smithkline Beckman Corporation	Anti-hypertensive use of 1-(4'-branched alkylsulfonylphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepines

1984
- 1984-04-26 US US06/604,101 patent/US4600714A/en not_active Expired - Fee Related
1985
- 1985-04-19 CA CA000479559A patent/CA1248098A/en not_active Expired
- 1985-04-22 AU AU41476/85A patent/AU582575B2/en not_active Ceased
- 1985-04-22 ZA ZA852983A patent/ZA852983B/xx unknown
- 1985-04-24 JP JP60089881A patent/JPS60233059A/ja active Pending
- 1985-04-24 PT PT80351A patent/PT80351B/pt unknown
- 1985-04-25 AT AT85302892T patent/ATE29717T1/de not_active IP Right Cessation
- 1985-04-25 ES ES542551A patent/ES8604883A1/es not_active Expired
- 1985-04-25 EP EP85302892A patent/EP0160513B1/de not_active Expired
- 1985-04-25 DK DK184685A patent/DK184685A/da not_active Application Discontinuation
- 1985-04-25 DE DE8585302892T patent/DE3560633D1/de not_active Expired

Also Published As

Publication number	Publication date
ZA852983B (en)	1986-10-29
AU4147685A (en)	1985-10-31
US4600714A (en)	1986-07-15
ES8604883A1 (es)	1986-03-01
PT80351A (en)	1985-05-01
DK184685A (da)	1985-10-27
AU582575B2 (en)	1989-04-06
EP0160513B1 (de)	1987-09-16
CA1248098A (en)	1989-01-03
EP0160513A1 (de)	1985-11-06
PT80351B (en)	1986-11-13
JPS60233059A (ja)	1985-11-19
ES542551A0 (es)	1986-03-01
DK184685D0 (da)	1985-04-25
DE3560633D1 (de)	1987-10-22

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Legal Events

Date	Code	Title	Description
1988-04-15	UEP	Publication of translation of european patent specification
1991-01-15	REN	Ceased due to non-payment of the annual fee