ATE297229T1 - Rekonstruierter muskel - Google Patents

Rekonstruierter muskel

Info

Publication number
ATE297229T1
ATE297229T1 AT00953780T AT00953780T ATE297229T1 AT E297229 T1 ATE297229 T1 AT E297229T1 AT 00953780 T AT00953780 T AT 00953780T AT 00953780 T AT00953780 T AT 00953780T AT E297229 T1 ATE297229 T1 AT E297229T1
Authority
AT
Austria
Prior art keywords
extracellular matrix
muscle
reconstructed
mandrel
matrix
Prior art date
Application number
AT00953780T
Other languages
English (en)
Inventor
Gary Bowlin
Gary Wnek
David Simpson
Louis Terracio
Original Assignee
Univ Virginia Commonwealth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/386,273 external-priority patent/US6592623B1/en
Application filed by Univ Virginia Commonwealth filed Critical Univ Virginia Commonwealth
Application granted granted Critical
Publication of ATE297229T1 publication Critical patent/ATE297229T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3826—Muscle cells, e.g. smooth muscle cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3873—Muscle tissue, e.g. sphincter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/30—Materials or treatment for tissue regeneration for muscle reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rehabilitation Therapy (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Saccharide Compounds (AREA)
  • Braking Arrangements (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Eye Examination Apparatus (AREA)
AT00953780T 1999-08-31 2000-08-02 Rekonstruierter muskel ATE297229T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/386,273 US6592623B1 (en) 1999-08-31 1999-08-31 Engineered muscle
US51208100A 2000-02-24 2000-02-24
PCT/US2000/020974 WO2001015754A1 (en) 1999-08-31 2000-08-02 Engineered muscle

Publications (1)

Publication Number Publication Date
ATE297229T1 true ATE297229T1 (de) 2005-06-15

Family

ID=27011345

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00953780T ATE297229T1 (de) 1999-08-31 2000-08-02 Rekonstruierter muskel

Country Status (11)

Country Link
EP (1) EP1212107B1 (de)
JP (2) JP2003508130A (de)
KR (1) KR20020059382A (de)
AT (1) ATE297229T1 (de)
AU (1) AU6617300A (de)
BR (1) BR0013639A (de)
CA (1) CA2383145A1 (de)
DE (1) DE60020721T2 (de)
MX (1) MXPA02002268A (de)
PL (1) PL353742A1 (de)
WO (1) WO2001015754A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7615373B2 (en) 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
US20020081732A1 (en) 2000-10-18 2002-06-27 Bowlin Gary L. Electroprocessing in drug delivery and cell encapsulation
CA2457162A1 (en) 2000-09-01 2002-03-07 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed fibrin-based matrices and tissues
AU2001287023A1 (en) * 2000-09-01 2002-03-13 Virginia Commonwealth University Intellectual Property Foundation Plasma-derived-fibrin-based matrices and tissue
WO2002022059A1 (en) * 2000-09-12 2002-03-21 Virginia Commonwealth University Treatment for high pressure bleeding
US20040013715A1 (en) 2001-09-12 2004-01-22 Gary Wnek Treatment for high pressure bleeding
AU2002224387B2 (en) 2000-10-18 2008-02-14 Virginia Commonwealth University Intellectual Property Foundation Electroprocessing in drug delivery and cell encapsulation
DE60135019D1 (de) 2000-11-17 2008-09-04 Univ Virginia Commonwealth Elektroverarbeitetes kollagen
US7762801B2 (en) 2004-04-08 2010-07-27 Research Triangle Institute Electrospray/electrospinning apparatus and method
US7134857B2 (en) 2004-04-08 2006-11-14 Research Triangle Institute Electrospinning of fibers using a rotatable spray head
US7297305B2 (en) 2004-04-08 2007-11-20 Research Triangle Institute Electrospinning in a controlled gaseous environment
US7592277B2 (en) 2005-05-17 2009-09-22 Research Triangle Institute Nanofiber mats and production methods thereof
WO2008047766A1 (en) * 2006-10-17 2008-04-24 Shoji Yamamoto Cardiac performance simulation system, cardiac performance simulation method, cardiac performance simulation program and composite material sheet
WO2010042207A2 (en) 2008-10-09 2010-04-15 Mimedx, Inc. Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and patches
JP2011130995A (ja) * 2009-12-25 2011-07-07 Japan Health Science Foundation 管腔構造体及び管腔構造体の製造方法
US10227568B2 (en) 2011-03-22 2019-03-12 Nanofiber Solutions, Llc Fiber scaffolds for use in esophageal prostheses
KR101318393B1 (ko) * 2011-06-15 2013-10-15 한국기계연구원 세포배양지지체의 제조장치 및 세포배양지지체의 제조방법
US9126366B2 (en) 2011-06-15 2015-09-08 Korea Institute Of Machinery & Materials Apparatus and method for manufacturing cell culture scaffold
US8986378B2 (en) 2011-11-02 2015-03-24 Mimedx Group, Inc. Implantable collagen devices and related methods and systems of making same
US10239262B2 (en) 2011-11-21 2019-03-26 Nanofiber Solutions, Llc Fiber scaffolds for use in tracheal prostheses
WO2013106822A1 (en) 2012-01-12 2013-07-18 Johnson Jed K Nanofiber scaffolds for biological structures
EP3950019A1 (de) * 2013-03-15 2022-02-09 Nanofiber Solutions, LLC Biokompatible fasertextilien zur implantation
WO2015048224A1 (en) 2013-09-25 2015-04-02 Johnson Jed K Fiber scaffolds for use creating implantable structures
US10279540B2 (en) 2014-02-20 2019-05-07 Okinawa Institute Of Science And Technology Schoo Controllable and reversible pH-responsive rollable 2D nano structures
US10166315B2 (en) 2015-05-04 2019-01-01 Nanofiber Solutions, Inc. Chitosan-enhanced electrospun fiber compositions
EP3370788A4 (de) 2015-11-02 2019-07-31 Nanofiber Solutions, LLC Elektrogesponnene fasern mit kontrastmitteln und verfahren zur herstellung davon
AU2017225766B2 (en) 2016-03-02 2021-12-16 The Regents Of The University Of Michigan Engineered tendon graft for rotator cuff repair
WO2018144858A1 (en) 2017-02-02 2018-08-09 Nanofiber Solutions, Inc. Methods of improving bone-soft tissue healing using electrospun fibers
CN108434525A (zh) * 2018-03-06 2018-08-24 西安交通大学 一种带血管网的人工肌组织及其制备方法
US11576927B2 (en) 2018-12-11 2023-02-14 Nanofiber Solutions, Llc Methods of treating chronic wounds using electrospun fibers
CN115551995B (zh) * 2020-03-26 2025-04-18 国立大学法人大阪大学 通过生物打印制造的肌肉组织
DK3988138T3 (da) * 2020-10-22 2024-02-26 Georg August Univ Goettingen Stiftung Oeffentlichen Rechts Univsmedizin Flerlaget kunstig hjertemuskel
CN113875878A (zh) * 2021-08-31 2022-01-04 深圳市星期零食品科技有限公司 一种植物蛋白肉仿生纤维的加工方法
CN115029867A (zh) * 2022-06-22 2022-09-09 北京建筑大学 一种胞外聚合物复合纳米纤维膜的制备方法

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US4600533A (en) * 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
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US5863531A (en) * 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
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GB2195251A (en) * 1986-09-02 1988-04-07 Ethicon Inc Improvements in synthetic vascular grafts
EP0334567A3 (de) * 1988-03-21 1990-04-25 Ethicon, Inc. Synthetisches Gefässtransplantat
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
GB8917916D0 (en) * 1989-08-04 1989-09-20 Ethicon Inc Improvements in synthetic vascular grafts and their methods of manufacture
JPH03161563A (ja) * 1989-11-17 1991-07-11 I C I Japan Kk 繊維状集合体
US5171579A (en) * 1991-10-11 1992-12-15 Genetics Institute, Inc. Formulations of blood clot-polymer matrix for delivery of osteogenic proteins
DE4219321A1 (de) * 1992-06-12 1993-12-16 Draenert Klaus Polymergranulat und Verfahren zu seiner Herstellung
JPH10505250A (ja) * 1994-06-06 1998-05-26 ケース ウエスターン リザーブ ユニバーシティ 組織再生のためのバイオマトリックス
US5714359A (en) * 1995-10-12 1998-02-03 The University Of Akron Apparatus and method for electrostatic endothelial cell seeding in a vascular prosthesis

Also Published As

Publication number Publication date
PL353742A1 (en) 2003-12-01
CA2383145A1 (en) 2001-03-08
AU6617300A (en) 2001-03-26
EP1212107A1 (de) 2002-06-12
MXPA02002268A (es) 2003-08-20
KR20020059382A (ko) 2002-07-12
DE60020721T2 (de) 2006-03-16
DE60020721D1 (de) 2005-07-14
JP2011131076A (ja) 2011-07-07
WO2001015754A1 (en) 2001-03-08
JP2003508130A (ja) 2003-03-04
EP1212107B1 (de) 2005-06-08
BR0013639A (pt) 2004-06-15

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