ATE297884T1 - Verfahren zur herstellung von 2-(4-(2,2,- dihalocyclopropyl)phenoxy)-alkansäuren und ihre estern - Google Patents

Verfahren zur herstellung von 2-(4-(2,2,- dihalocyclopropyl)phenoxy)-alkansäuren und ihre estern

Info

Publication number: ATE297884T1
Authority: AT; Austria
Prior art keywords: dihalocyclopropyl; phenoxy; esters; producing; alkanoic acids
Prior art date: 2001-05-08

Application number

AT02727585T

Other languages

English (en)

Inventor

Flavio Villani

Antonio Nardi

Annibale Salvi

Giovanna Falabella

Original Assignee

Laboratorio Chimico Int Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-08

Filing date

2002-04-30

Publication date

2005-07-15

2002-04-30 Application filed by Laboratorio Chimico Int Spa filed Critical Laboratorio Chimico Int Spa

2005-07-15 Application granted granted Critical

2005-07-15 Publication of ATE297884T1 publication Critical patent/ATE297884T1/de

Links

150000002148 esters Chemical class 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
KHUXNRRPPZOJPT-UHFFFAOYSA-N phenoxy radical Chemical class O=C1C=C[CH]C=C1 KHUXNRRPPZOJPT-UHFFFAOYSA-N 0.000 title 1
238000006220 Baeyer-Villiger oxidation reaction Methods 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/39—Preparation of carboxylic acid esters by oxidation of groups which are precursors for the acid moiety of the ester
- C07C67/42—Preparation of carboxylic acid esters by oxidation of groups which are precursors for the acid moiety of the ester by oxidation of secondary alcohols or ketones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT02727585T 2001-05-08 2002-04-30 Verfahren zur herstellung von 2-(4-(2,2,- dihalocyclopropyl)phenoxy)-alkansäuren und ihre estern ATE297884T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2001MI000936A ITMI20010936A1 (it)	2001-05-08	2001-05-08	Processo per la produzione di acidi 2-4-(2,2-dialociclopropil)fenossi\|-alcanoici e loro esteri
PCT/EP2002/004747 WO2002090307A1 (en)	2001-05-08	2002-04-30	2-[4-(2, 2-dihalocyclopropyl)phenoxy]-alkanoic acids and esters thereof production process

Publications (1)

Publication Number	Publication Date
ATE297884T1 true ATE297884T1 (de)	2005-07-15

Family

ID=11447607

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02727585T ATE297884T1 (de)	2001-05-08	2002-04-30	Verfahren zur herstellung von 2-(4-(2,2,- dihalocyclopropyl)phenoxy)-alkansäuren und ihre estern

Country Status (7)

Country	Link
EP (1)	EP1387822B1 (de)
CN (1)	CN1238324C (de)
AT (1)	ATE297884T1 (de)
DE (1)	DE60204681T2 (de)
ES (1)	ES2244770T3 (de)
IT (1)	ITMI20010936A1 (de)
WO (1)	WO2002090307A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2892721B1 (fr)	2005-10-28	2009-07-24	Synkem Sa	Nouveau procede de preparation de sels d'acides et d'ammonium quaternaires
CN103342637B (zh) *	2013-06-14	2015-08-12	苏州汇和药业有限公司	一种高纯度环丙贝特的精制方法
CN103613498B (zh) *	2013-11-20	2015-08-26	浙江三门恒康制药有限公司	环丙贝特的合成方法
CN104909994A (zh) *	2015-04-10	2015-09-16	浙江三门恒康制药有限公司	环丙贝特中间体的合成方法及中间体
CN105152925B (zh) *	2015-10-08	2017-12-01	常州强达宝成化工有限公司	环丙贝特的合成方法
CN108658764A (zh) *	2018-06-01	2018-10-16	新昌县泰如科技有限公司	一种4-（2,2-二氯环丙基）苯酚乙酸酯的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3948973A (en) *	1972-08-29	1976-04-06	Sterling Drug Inc.	Halocyclopropyl substituted phenoxyalkanoic acids
FR2598146B1 (fr) *	1986-04-30	1989-01-20	Rech Ind	Nouveau procede de preparation de fibrates.
IT1244036B (it) *	1990-12-19	1994-06-28	Zambon Spa	Processo per la preparazione del 4-nitro-benzoato di 4-(2,4- difluorofenil)-fenile

2001
- 2001-05-08 IT IT2001MI000936A patent/ITMI20010936A1/it unknown
2002
- 2002-04-30 CN CNB028094778A patent/CN1238324C/zh not_active Expired - Fee Related
- 2002-04-30 DE DE60204681T patent/DE60204681T2/de not_active Expired - Lifetime
- 2002-04-30 EP EP02727585A patent/EP1387822B1/de not_active Expired - Lifetime
- 2002-04-30 AT AT02727585T patent/ATE297884T1/de not_active IP Right Cessation
- 2002-04-30 WO PCT/EP2002/004747 patent/WO2002090307A1/en not_active Ceased
- 2002-04-30 ES ES02727585T patent/ES2244770T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CN1514819A (zh)	2004-07-21
CN1238324C (zh)	2006-01-25
DE60204681T2 (de)	2006-05-18
DE60204681D1 (de)	2005-07-21
ITMI20010936A1 (it)	2002-11-08
WO2002090307A1 (en)	2002-11-14
ITMI20010936A0 (it)	2001-05-08
EP1387822A1 (de)	2004-02-11
EP1387822B1 (de)	2005-06-15
ES2244770T3 (es)	2005-12-16

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Legal Events

Date	Code	Title	Description
2005-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties