ATE298081T1 - Bilderzeugungsvorrichtung mit einem laser unter verwendung von biomedizinischen markern, die sich an krebszellen binden - Google Patents

Bilderzeugungsvorrichtung mit einem laser unter verwendung von biomedizinischen markern, die sich an krebszellen binden

Info

Publication number
ATE298081T1
ATE298081T1 AT99916113T AT99916113T ATE298081T1 AT E298081 T1 ATE298081 T1 AT E298081T1 AT 99916113 T AT99916113 T AT 99916113T AT 99916113 T AT99916113 T AT 99916113T AT E298081 T1 ATE298081 T1 AT E298081T1
Authority
AT
Austria
Prior art keywords
cancer cells
laser beam
bind
imaging device
laser imaging
Prior art date
Application number
AT99916113T
Other languages
English (en)
Inventor
Robert H Wake
Richard J Grable
Original Assignee
Imaging Diagnostic Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imaging Diagnostic Systems Inc filed Critical Imaging Diagnostic Systems Inc
Application granted granted Critical
Publication of ATE298081T1 publication Critical patent/ATE298081T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0091—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for mammography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312—Breast evaluation or disorder diagnosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Laser Surgery Devices (AREA)
  • Radiation-Therapy Devices (AREA)
AT99916113T 1997-01-17 1999-04-01 Bilderzeugungsvorrichtung mit einem laser unter verwendung von biomedizinischen markern, die sich an krebszellen binden ATE298081T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US3608897P 1997-01-17 1997-01-17
US6359097P 1997-10-30 1997-10-30
US09/008,477 US5952664A (en) 1997-01-17 1998-01-16 Laser imaging apparatus using biomedical markers that bind to cancer cells
PCT/US1999/004287 WO2000060323A1 (en) 1997-01-17 1999-04-01 Laser imaging apparatus using biomedical markers that bind to cancer cells

Publications (1)

Publication Number Publication Date
ATE298081T1 true ATE298081T1 (de) 2005-07-15

Family

ID=27485783

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99916113T ATE298081T1 (de) 1997-01-17 1999-04-01 Bilderzeugungsvorrichtung mit einem laser unter verwendung von biomedizinischen markern, die sich an krebszellen binden

Country Status (9)

Country Link
US (2) US5952664A (de)
EP (2) EP1477785A1 (de)
AT (1) ATE298081T1 (de)
AU (1) AU775069B2 (de)
CA (1) CA2373299C (de)
DE (1) DE69925869T2 (de)
HK (1) HK1043480B (de)
MX (1) MXPA01010466A (de)
WO (1) WO2000060323A1 (de)

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US6100520A (en) * 1996-11-29 2000-08-08 Imaging Diagnostic Systems, Inc. Detector array for use in a laser imaging apparatus
EP1006866A4 (de) 1996-11-29 2000-06-14 Imaging Diagnostic Systems Inc Detektor-anordnung zum gebrauch in einem laser-bilderzeugungsgerät
US5952664A (en) * 1997-01-17 1999-09-14 Imaging Diagnostic Systems, Inc. Laser imaging apparatus using biomedical markers that bind to cancer cells
US6592847B1 (en) * 1998-05-14 2003-07-15 The General Hospital Corporation Intramolecularly-quenched near infrared flourescent probes
WO2000046979A2 (en) * 1999-02-05 2000-08-10 Imaging Diagnostic Systems, Inc. Ccd array as a multiple-detector in an optical imaging apparatus
US7840257B2 (en) 2003-01-04 2010-11-23 Non Invasive Technology, Inc. Examination of biological tissue using non-contact optical probes
US7904139B2 (en) * 1999-08-26 2011-03-08 Non-Invasive Technology Inc. Optical examination of biological tissue using non-contact irradiation and detection
US6317616B1 (en) * 1999-09-15 2001-11-13 Neil David Glossop Method and system to facilitate image guided surgery
US7006676B1 (en) 2000-01-21 2006-02-28 Medical Optical Imaging, Inc. Method and apparatus for detecting an abnormality within a host medium utilizing frequency-swept modulation diffusion tomography
EP1284654A4 (de) * 2000-05-09 2004-03-24 Imaging Diagnostic Systems Inc Medizinischer optischer bildgebungsscanner unter verwendung von simultaner multiwellenlängendatengewinnung zur brustbildgebung
US6615063B1 (en) 2000-11-27 2003-09-02 The General Hospital Corporation Fluorescence-mediated molecular tomography
US7383076B2 (en) * 2000-11-27 2008-06-03 The General Hospital Corporation Fluorescence-mediated molecular tomography
US6542769B2 (en) 2000-12-18 2003-04-01 The General Hospital Corporation Imaging system for obtaining quantative perfusion indices
US20030044353A1 (en) * 2001-01-05 2003-03-06 Ralph Weissleder Activatable imaging probes
JP4781548B2 (ja) * 2001-03-14 2011-09-28 浜松ホトニクス株式会社 乳がん検出装置
US7016717B2 (en) * 2002-07-05 2006-03-21 The Regents Of The University Of California Near-infrared spectroscopic tissue imaging for medical applications
US20040068180A1 (en) * 2002-10-04 2004-04-08 Jeffrey Collins Rotary ultrasound scanner for soft tissue examination
US7555334B2 (en) * 2003-10-20 2009-06-30 Xenogen Corporation Small animal light intensity monitor
US7155274B1 (en) * 2003-11-21 2006-12-26 Imaging Diagnostic Systems, Inc. Optical computed tomography scanner for small laboratory animals
US8068896B2 (en) * 2005-02-25 2011-11-29 Intramedical Imaging, Llc Detection of radiation labeled sites using a radiation detection probe or camera incorporating a solid state photo-multiplier
US7714268B2 (en) * 2005-09-08 2010-05-11 Koninklijke Philips Electronics N.V. Determination of low currents with high dynamic range for optical imaging
JP2009515630A (ja) * 2005-11-18 2009-04-16 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 濁質の内部を画像化する装置
EP1956966A2 (de) * 2005-11-25 2008-08-20 Philips Intellectual Property & Standards GmbH Optische fluoreszenz-tomographie
RU2454921C2 (ru) * 2006-07-07 2012-07-10 Конинклейке Филипс Электроникс Н.В. Оптическая отображающая система и способ
EP2049886A2 (de) * 2006-07-31 2009-04-22 Koninklijke Philips Electronics N.V. Schnell fluoreszierende abbildungsvorrichtung für diffuse optische tomographie
EP2244741B1 (de) 2008-01-18 2015-03-25 VisEn Medical, Inc. Fluoreszierende bildgebungsmittel
EP2274051A4 (de) * 2008-05-09 2011-07-20 Hugh Beckman Medizinisches gerät zur diagnostizierung und behandlung von gewebeanomalien und verfahren dafür
CA2724973C (en) 2008-05-20 2015-08-11 University Health Network Device and method for fluorescence-based imaging and monitoring
WO2015138343A1 (en) 2014-03-10 2015-09-17 Click Diagnostics, Inc. Cartridge-based thermocycler
WO2016011534A1 (en) 2014-07-24 2016-01-28 University Health Network Collection and analysis of data for diagnostic purposes
US9623415B2 (en) 2014-12-31 2017-04-18 Click Diagnostics, Inc. Devices and methods for molecular diagnostic testing
WO2017197040A1 (en) 2016-05-11 2017-11-16 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
EP3478857A1 (de) 2016-06-29 2019-05-08 Click Diagnostics, Inc. Vorrichtungen und verfahren zur detektion von molekülen unter verwendung einer durchflusszelle
MX2020004783A (es) 2017-11-09 2020-08-13 Visby Medical Inc Dispositivo portatil para el diagnostico molecular y metodos para la deteccion de virus objetivo.
US12263478B2 (en) 2019-04-28 2025-04-01 Visby Medical, Inc. Molecular diagnostic devices with digital detection capability and wireless connectivity

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US5205291A (en) * 1988-11-08 1993-04-27 Health Research, Inc. In vivo fluorescence photometer
US5353799A (en) * 1991-01-22 1994-10-11 Non Invasive Technology, Inc. Examination of subjects using photon migration with high directionality techniques
US5555885A (en) * 1988-12-21 1996-09-17 Non-Invasive Technology, Inc. Examination of breast tissue using time-resolved spectroscopy
DE4129438A1 (de) * 1991-09-04 1993-03-18 Siemens Ag Messanordnung fuer die untersuchung eines objektes mit sichtbarem, nir- oder ir-licht
US5330741A (en) * 1992-02-24 1994-07-19 The Regents Of The University Of California Long-wavelength water soluble chlorin photosensitizers useful for photodynamic therapy and diagnosis of tumors
JP3565442B2 (ja) * 1993-04-22 2004-09-15 新日本石油化学株式会社 哺乳類の関節炎の診断剤および／または治療剤
US5692511A (en) * 1995-06-07 1997-12-02 Grable; Richard J. Diagnostic tomographic laser imaging apparatus
EP0846262A4 (de) * 1995-08-24 1999-11-03 Purdue Research Foundation Abbildung von spektroskopie von gewebe und anderen stark streuenden medien, basierend auf fluoreszenz lebensdauer
JP3621704B2 (ja) * 1995-09-26 2005-02-16 カール．ストルツ．ゲゼルシャフト．ミット．ベシュレンクテル．ハフツング．ウント．カンパニー 光力学的診断用装置
US5719399A (en) * 1995-12-18 1998-02-17 The Research Foundation Of City College Of New York Imaging and characterization of tissue based upon the preservation of polarized light transmitted therethrough
JP3662376B2 (ja) * 1996-05-10 2005-06-22 浜松ホトニクス株式会社 内部特性分布の計測方法および装置
EP1006866A4 (de) * 1996-11-29 2000-06-14 Imaging Diagnostic Systems Inc Detektor-anordnung zum gebrauch in einem laser-bilderzeugungsgerät
US5952664A (en) * 1997-01-17 1999-09-14 Imaging Diagnostic Systems, Inc. Laser imaging apparatus using biomedical markers that bind to cancer cells

Also Published As

Publication number Publication date
US6693287B2 (en) 2004-02-17
CA2373299C (en) 2004-03-30
EP1181511A1 (de) 2002-02-27
AU3449399A (en) 2000-10-23
EP1477785A1 (de) 2004-11-17
EP1181511A4 (de) 2002-09-25
US5952664A (en) 1999-09-14
US20020114765A1 (en) 2002-08-22
WO2000060323A1 (en) 2000-10-12
HK1043480B (en) 2006-01-27
DE69925869D1 (de) 2005-07-21
CA2373299A1 (en) 2000-10-12
EP1181511B1 (de) 2005-06-15
DE69925869T2 (de) 2006-05-04
AU775069B2 (en) 2004-07-15
HK1043480A1 (en) 2002-09-13
MXPA01010466A (es) 2003-08-20

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