ATE298463T1 - Verfahren zur reduzierung der raumladung in einem linearen quadrupol-ionenfalle-massenspektrometer - Google Patents

Verfahren zur reduzierung der raumladung in einem linearen quadrupol-ionenfalle-massenspektrometer

Info

Publication number
ATE298463T1
ATE298463T1 AT02754034T AT02754034T ATE298463T1 AT E298463 T1 ATE298463 T1 AT E298463T1 AT 02754034 T AT02754034 T AT 02754034T AT 02754034 T AT02754034 T AT 02754034T AT E298463 T1 ATE298463 T1 AT E298463T1
Authority
AT
Austria
Prior art keywords
mass spectrometer
ion trap
ion
trap
space charge
Prior art date
Application number
AT02754034T
Other languages
English (en)
Inventor
James W Hager
Original Assignee
Mds Inc Dba Mds Sciex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mds Inc Dba Mds Sciex filed Critical Mds Inc Dba Mds Sciex
Application granted granted Critical
Publication of ATE298463T1 publication Critical patent/ATE298463T1/de

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/426—Methods for controlling ions
    • H01J49/4265—Controlling the number of trapped ions; preventing space charge effects
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps
    • H01J49/4225—Multipole linear ion traps, e.g. quadrupoles, hexapoles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S430/00—Radiation imagery chemistry: process, composition, or product thereof
    • Y10S430/143—Electron beam

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AT02754034T 2001-08-30 2002-08-14 Verfahren zur reduzierung der raumladung in einem linearen quadrupol-ionenfalle-massenspektrometer ATE298463T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31571501P 2001-08-30 2001-08-30
PCT/CA2002/001257 WO2003019614A2 (en) 2001-08-30 2002-08-14 A method of reducing space charge in a linear ion trap mass spectrometer

Publications (1)

Publication Number Publication Date
ATE298463T1 true ATE298463T1 (de) 2005-07-15

Family

ID=23225723

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02754034T ATE298463T1 (de) 2001-08-30 2002-08-14 Verfahren zur reduzierung der raumladung in einem linearen quadrupol-ionenfalle-massenspektrometer

Country Status (8)

Country Link
US (2) US20040238737A1 (de)
EP (1) EP1421600B1 (de)
JP (1) JP4303108B2 (de)
AT (1) ATE298463T1 (de)
AU (1) AU2002322895A1 (de)
CA (1) CA2457631C (de)
DE (1) DE60204785T2 (de)
WO (1) WO2003019614A2 (de)

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US6720554B2 (en) * 2000-07-21 2004-04-13 Mds Inc. Triple quadrupole mass spectrometer with capability to perform multiple mass analysis steps
WO2003019614A2 (en) * 2001-08-30 2003-03-06 Mds Inc., Doing Busness As Mds Sciex A method of reducing space charge in a linear ion trap mass spectrometer
US7045797B2 (en) * 2002-08-05 2006-05-16 The University Of British Columbia Axial ejection with improved geometry for generating a two-dimensional substantially quadrupole field
US6897438B2 (en) * 2002-08-05 2005-05-24 University Of British Columbia Geometry for generating a two-dimensional substantially quadrupole field
CN101685755B (zh) * 2003-01-24 2011-12-14 萨莫芬尼根有限责任公司 控制质量分析器中的离子数目
GB0312940D0 (en) * 2003-06-05 2003-07-09 Shimadzu Res Lab Europe Ltd A method for obtaining high accuracy mass spectra using an ion trap mass analyser and a method for determining and/or reducing chemical shift in mass analysis
CA2539221A1 (en) * 2003-09-25 2005-03-31 Mds Inc., Doing Business As Mds Sciex Method and apparatus for providing two-dimensional substantially quadrupole fields having selected hexapole components
DE102004001514A1 (de) * 2004-01-09 2005-08-04 Marcus Dr.-Ing. Gohl Verfahren und Vorrichtung zur Bestimmung des Schmierölgehalts in einem Abgasgemisch
US7709785B2 (en) * 2005-05-18 2010-05-04 Mds Inc. Method and apparatus for mass selective axial transport using quadrupolar DC
GB0511083D0 (en) 2005-05-31 2005-07-06 Thermo Finnigan Llc Multiple ion injection in mass spectrometry
DE102005025498B4 (de) * 2005-06-03 2008-12-24 Bruker Daltonik Gmbh Füllstandsregelung in Ionenzyklotronresonanz- Massenspetrometern
JP4636943B2 (ja) * 2005-06-06 2011-02-23 株式会社日立ハイテクノロジーズ 質量分析装置
JP4369454B2 (ja) 2006-09-04 2009-11-18 株式会社日立ハイテクノロジーズ イオントラップ質量分析方法
US7633059B2 (en) 2006-10-13 2009-12-15 Agilent Technologies, Inc. Mass spectrometry system having ion deflector
GB0624679D0 (en) * 2006-12-11 2007-01-17 Shimadzu Corp A time-of-flight mass spectrometer and a method of analysing ions in a time-of-flight mass spectrometer
US8334506B2 (en) 2007-12-10 2012-12-18 1St Detect Corporation End cap voltage control of ion traps
US7629575B2 (en) * 2007-12-19 2009-12-08 Varian, Inc. Charge control for ionic charge accumulation devices
US7973277B2 (en) 2008-05-27 2011-07-05 1St Detect Corporation Driving a mass spectrometer ion trap or mass filter
EP2308077B1 (de) * 2008-06-09 2019-09-11 DH Technologies Development Pte. Ltd. Verfahren für den betrieb von tandemionenfallen
US8008618B2 (en) * 2008-06-09 2011-08-30 Frank Londry Multipole ion guide for providing an axial electric field whose strength increases with radial position, and a method of operating a multipole ion guide having such an axial electric field
US8822916B2 (en) 2008-06-09 2014-09-02 Dh Technologies Development Pte. Ltd. Method of operating tandem ion traps
GB0810599D0 (en) 2008-06-10 2008-07-16 Micromass Ltd Mass spectrometer
US20100096544A1 (en) * 2008-10-16 2010-04-22 Battelle Memorial Institute Surface Sampling Probe for Field Portable Surface Sampling Mass Spectrometer
GB0900917D0 (en) 2009-01-20 2009-03-04 Micromass Ltd Mass spectrometer
US20100237236A1 (en) * 2009-03-20 2010-09-23 Applera Corporation Method Of Processing Multiple Precursor Ions In A Tandem Mass Spectrometer
US8552365B2 (en) * 2009-05-11 2013-10-08 Thermo Finnigan Llc Ion population control in a mass spectrometer having mass-selective transfer optics
GB2490958B (en) * 2011-05-20 2016-02-10 Thermo Fisher Scient Bremen Method and apparatus for mass analysis
US9318310B2 (en) * 2011-07-11 2016-04-19 Dh Technologies Development Pte. Ltd. Method to control space charge in a mass spectrometer
EP2786399B1 (de) * 2011-11-29 2019-10-09 Thermo Finnigan LLC Verfahren zur automatisierten prüfung und einstellung einer massenspektrometer-kalibrierung
WO2013093582A2 (en) * 2011-12-23 2013-06-27 Dh Technologies Development Pte. Ltd. Method and system for quantitative and qualitative analysis using mass spectrometry
US8759752B2 (en) 2012-03-12 2014-06-24 Thermo Finnigan Llc Corrected mass analyte values in a mass spectrum
WO2014140622A1 (en) 2013-03-14 2014-09-18 Micromass Uk Limited Improved method of data dependent control
US8969794B2 (en) * 2013-03-15 2015-03-03 1St Detect Corporation Mass dependent automatic gain control for mass spectrometer
GB201307404D0 (en) * 2013-04-24 2013-06-05 Micromass Ltd Improved ion mobility spectrometer
US10088451B2 (en) 2013-04-24 2018-10-02 Micromass Uk Limited Ion mobility spectrometer
GB201316164D0 (en) 2013-09-11 2013-10-23 Thermo Fisher Scient Bremen Targeted mass analysis
EP3321953B1 (de) * 2016-11-10 2019-06-26 Thermo Finnigan LLC Systeme und verfahren zur skalierung einer injektion-wellenformsamplitude während der ionenisolation
US10128099B1 (en) * 2017-07-20 2018-11-13 Thermo Finnigan Llc Systems and methods for regulating the ion population in an ion trap for MSn scans
CN113366609B (zh) * 2019-02-01 2025-03-11 Dh科技发展私人贸易有限公司 用于优化离子阱填充的自动增益控制
GB201906546D0 (en) 2019-05-09 2019-06-26 Thermo Fisher Scient Bremen Gmbh Charge detection for ion current control

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US6011259A (en) * 1995-08-10 2000-01-04 Analytica Of Branford, Inc. Multipole ion guide ion trap mass spectrometry with MS/MSN analysis
US5420425A (en) * 1994-05-27 1995-05-30 Finnigan Corporation Ion trap mass spectrometer system and method
US5572022A (en) * 1995-03-03 1996-11-05 Finnigan Corporation Method and apparatus of increasing dynamic range and sensitivity of a mass spectrometer
US6177668B1 (en) * 1996-06-06 2001-01-23 Mds Inc. Axial ejection in a multipole mass spectrometer
WO2003019614A2 (en) * 2001-08-30 2003-03-06 Mds Inc., Doing Busness As Mds Sciex A method of reducing space charge in a linear ion trap mass spectrometer

Also Published As

Publication number Publication date
DE60204785D1 (de) 2005-07-28
EP1421600A2 (de) 2004-05-26
AU2002322895A1 (en) 2003-03-10
JP2005500662A (ja) 2005-01-06
US6627876B2 (en) 2003-09-30
US20030042415A1 (en) 2003-03-06
US20040238737A1 (en) 2004-12-02
EP1421600B1 (de) 2005-06-22
WO2003019614A2 (en) 2003-03-06
CA2457631C (en) 2010-04-27
CA2457631A1 (en) 2003-03-06
JP4303108B2 (ja) 2009-07-29
WO2003019614A3 (en) 2003-06-19
DE60204785T2 (de) 2006-05-04

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