ATE299697T1 - Feste zubereitungen mit ramipril - Google Patents
Feste zubereitungen mit ramiprilInfo
- Publication number
- ATE299697T1 ATE299697T1 AT02758020T AT02758020T ATE299697T1 AT E299697 T1 ATE299697 T1 AT E299697T1 AT 02758020 T AT02758020 T AT 02758020T AT 02758020 T AT02758020 T AT 02758020T AT E299697 T1 ATE299697 T1 AT E299697T1
- Authority
- AT
- Austria
- Prior art keywords
- ramipril
- solid preparations
- hydrate
- mixture
- pharmaceutical composition
- Prior art date
Links
- HDACQVRGBOVJII-JBDAPHQKSA-N ramipril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](C[C@@H]2CCC[C@@H]21)C(O)=O)CC1=CC=CC=C1 HDACQVRGBOVJII-JBDAPHQKSA-N 0.000 title abstract 2
- 229960003401 ramipril Drugs 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- WSVLPVUVIUVCRA-KPKNDVKVSA-N Alpha-lactose monohydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-KPKNDVKVSA-N 0.000 abstract 1
- 229960001021 lactose monohydrate Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Road Signs Or Road Markings (AREA)
- Food-Manufacturing Devices (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002357982A CA2357982A1 (en) | 2001-09-28 | 2001-09-28 | Solid compositions comprising ramipril |
| PCT/CA2002/001379 WO2003028707A1 (en) | 2001-09-28 | 2002-09-12 | Solid compositions comprising ramipril |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE299697T1 true ATE299697T1 (de) | 2005-08-15 |
Family
ID=4170122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02758020T ATE299697T1 (de) | 2001-09-28 | 2002-09-12 | Feste zubereitungen mit ramipril |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050169981A1 (de) |
| EP (1) | EP1429748B1 (de) |
| AT (1) | ATE299697T1 (de) |
| CA (1) | CA2357982A1 (de) |
| DE (1) | DE60205125T2 (de) |
| WO (1) | WO2003028707A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2394660A (en) * | 2003-12-17 | 2004-05-05 | Niche Generics Ltd | Stabilisation of pharmaceutical compositions comprising ACE inhibitor by absence of acidic excipients having large specific surface area, eg silicon dioxide |
| GB2411355B (en) | 2004-02-27 | 2006-02-22 | Niche Generics Ltd | Pharmaceutical composition |
| WO2005067887A2 (en) * | 2004-03-24 | 2005-07-28 | Actavis Group | Formulations of ramipril |
| PT1729739T (pt) | 2004-03-29 | 2016-12-01 | Servier Lab | Processo para a preparação de uma composição farmacêutica sólida |
| KR100593795B1 (ko) * | 2004-10-12 | 2006-06-30 | 대원제약주식회사 | 안정성이 개선된 라미프릴을 포함하는 경구투여용 제제 |
| GB0518129D0 (en) * | 2005-09-06 | 2005-10-12 | Arrow Int Ltd | Ramipril formulation |
| US20070098782A1 (en) * | 2005-10-28 | 2007-05-03 | Selamine Limited | Ramipril Formulation |
| GB2431579A (en) * | 2005-10-28 | 2007-05-02 | Arrow Int Ltd | Ramipril formulations |
| GB0624090D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amine salts |
| GB0624087D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril combination salt |
| GB0624084D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amino acid salts |
| TR200906322A2 (tr) | 2009-08-17 | 2011-07-21 | Bi̇lgi̇ç Mahmut | Çözünürlük ve stabilite özellikleri geliştirilmiş granüller. |
| ES2364011B1 (es) | 2009-11-20 | 2013-01-24 | Gp Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares. |
| PL227900B1 (pl) | 2012-11-15 | 2018-01-31 | Adamed Spolka Z Ograniczona Odpowiedzialnoscia | Kompozycja farmaceutyczna zawierająca inhibitor ACE i bloker kanałów wapniowych, sposób jej wytwarzania i jednostka dawkowania zawierająca tę kompozycję |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3739690A1 (de) * | 1987-11-24 | 1989-06-08 | Hoechst Ag | Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen |
| DE4420102A1 (de) * | 1994-06-09 | 1995-12-14 | Asta Medica Ag | Arzneimittelkombinationen aus alpha-Liponsäure und herz-kreislaufaktiven Substanzen |
| US5562921A (en) * | 1994-07-15 | 1996-10-08 | Sherman; Bernard C. | Stable solid pharmaceutical compositions containing enalapril maleate |
| TW483763B (en) * | 1994-09-02 | 2002-04-21 | Astra Ab | Pharmaceutical composition comprising of ramipril and dihydropyridine compound |
| NZ333206A (en) * | 1998-12-08 | 2000-07-28 | Bernard Charles Sherman | Solid pharmaceutical compositions comprising a stable magnesium salt of quinapril that acts as a ACE (Angiotensin Converting Enzyme) inhibitor |
| DE10038364A1 (de) * | 2000-08-05 | 2002-05-02 | Hexal Ag | Pharmazeutische, Ramipril enthaltende Brauseformulierung |
-
2001
- 2001-09-28 CA CA002357982A patent/CA2357982A1/en not_active Abandoned
-
2002
- 2002-09-12 AT AT02758020T patent/ATE299697T1/de not_active IP Right Cessation
- 2002-09-12 DE DE60205125T patent/DE60205125T2/de not_active Expired - Fee Related
- 2002-09-12 WO PCT/CA2002/001379 patent/WO2003028707A1/en not_active Ceased
- 2002-09-12 US US10/489,774 patent/US20050169981A1/en not_active Abandoned
- 2002-09-12 EP EP02758020A patent/EP1429748B1/de not_active Revoked
Also Published As
| Publication number | Publication date |
|---|---|
| DE60205125D1 (de) | 2005-08-25 |
| US20050169981A1 (en) | 2005-08-04 |
| DE60205125T2 (de) | 2006-05-24 |
| CA2357982A1 (en) | 2003-03-28 |
| EP1429748A1 (de) | 2004-06-23 |
| EP1429748B1 (de) | 2005-07-20 |
| WO2003028707A1 (en) | 2003-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60205125D1 (de) | Feste zubereitungen mit ramipril | |
| PT1412384E (pt) | Formulação estável de glp-1 modificado | |
| HUP0101237A1 (hu) | Elnyújtott kioldódású gyógyszerkészítmények | |
| CY1108532T1 (el) | Ενωσεις και συνθεσεις για την παροχη δραστικων παραγοντων | |
| GEP20074047B (en) | Pramipexole once-daily dosage form | |
| WO2004043363A8 (en) | Protein-stabilized liposomal formulations of pharmaceutical agents | |
| HUP9803044A2 (hu) | Ibuprofentartalmú készítmény | |
| BR0210078A (pt) | Composto, uso do mesmo, e, formulação farmacêutica | |
| EE04911B1 (et) | Ühend ja farmatseutiline kompositsioon proteaasi inhibiitoritena, nende kasutamine ning meetod selle ühendi valmistamiseks | |
| NO20043367L (no) | Oralt farmasoytisk preparat | |
| EA200401517A1 (ru) | Фармацевтический препарат для местного применения | |
| AR021981A1 (es) | Composicion farmaceutica para una administracion por via oral destinada a evitar la desviacion de uso en detrimento de un tercero | |
| PL356358A1 (en) | Solid dosage form of someticone for oral administration | |
| DE60030741D1 (de) | Chinazoline verbindungen als heilmittel | |
| EA200300937A1 (ru) | Оральная фармацевтическая композиция цефподоксима проксетила | |
| ATE291908T1 (de) | Ibuprofen-wirkstoffzubereitung | |
| DE60336225D1 (de) | Neue pharmazeutische zusammenstezungen, flibanserin polymorph a enthaltend | |
| NO20013060D0 (no) | Kontrollert frigjörende farmasöytisk preparat med tilidinmesylat som virkestoff | |
| WO2003051398A8 (en) | Parenteral composition of paracetamol | |
| IS7097A (is) | Lyfjablanda til að gefa fúlvestrant í vöðva | |
| WO2001068645A3 (en) | N-cyanomethylcarboxamides and their use as protease inhibitors | |
| NO20014855D0 (no) | N-(2-fenyl-4-aminobutyl)-1-naftamider som neurokinin-1- reseptorantagonister | |
| BG108452A (en) | Tablet comprising cetirizine and pseudoephedrine | |
| ATE400563T1 (de) | Neue neurokinin-antagonisten zum gebrauch als arzneimittel | |
| AU2002341555A1 (en) | Levothyroxine pharmaceutical compositions, methods of making and methods of administration |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |