ATE30019T1 - Bicyclooxyarylthioharnstoffe und herstellungsverfahren. - Google Patents

Bicyclooxyarylthioharnstoffe und herstellungsverfahren.

Info

Publication number
ATE30019T1
ATE30019T1 AT84302209T AT84302209T ATE30019T1 AT E30019 T1 ATE30019 T1 AT E30019T1 AT 84302209 T AT84302209 T AT 84302209T AT 84302209 T AT84302209 T AT 84302209T AT E30019 T1 ATE30019 T1 AT E30019T1
Authority
AT
Austria
Prior art keywords
ring
carbocyclic
membered
mono
individually
Prior art date
Application number
AT84302209T
Other languages
English (en)
Inventor
Paul Alfred Cain
Original Assignee
Union Carbide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Union Carbide Corp filed Critical Union Carbide Corp
Application granted granted Critical
Publication of ATE30019T1 publication Critical patent/ATE30019T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/36—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/38—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring, e.g. nitrodiphenyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/24—Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
    • C07C335/26—Y being a hydrogen or a carbon atom, e.g. benzoylthioureas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
AT84302209T 1983-03-31 1984-03-30 Bicyclooxyarylthioharnstoffe und herstellungsverfahren. ATE30019T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/480,697 US4665097A (en) 1983-03-31 1983-03-31 Novel bicyclooxyaryl thioureas and process for preparation
EP84302209A EP0124282B1 (de) 1983-03-31 1984-03-30 Bicyclooxyarylthioharnstoffe und Herstellungsverfahren

Publications (1)

Publication Number Publication Date
ATE30019T1 true ATE30019T1 (de) 1987-10-15

Family

ID=23908972

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84302209T ATE30019T1 (de) 1983-03-31 1984-03-30 Bicyclooxyarylthioharnstoffe und herstellungsverfahren.

Country Status (6)

Country Link
US (1) US4665097A (de)
EP (1) EP0124282B1 (de)
JP (1) JPS59184155A (de)
AT (1) ATE30019T1 (de)
DE (1) DE3466532D1 (de)
DK (1) DK173684A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342958A (en) * 1970-05-15 1994-08-30 Solvay Duphar International Research B.V. Organic compounds derived from urea or thiourea
US5245071A (en) * 1970-05-15 1993-09-14 Duphar International Research B.V. Organic compounds derived from urea or thiourea
US5135953A (en) * 1984-12-28 1992-08-04 Ciba-Geigy Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals
CN1738797A (zh) 2002-11-19 2006-02-22 阿基里昂药品公司 取代的芳基硫脲和相关的化合物,病毒复制的抑制剂
TW200600492A (en) * 2004-05-18 2006-01-01 Achillion Pharmaceuticals Inc Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
SG11201601616SA (en) 2013-09-09 2016-04-28 Peloton Therapeutics Inc Aryl ethers and uses thereof
US9884843B2 (en) 2013-12-16 2018-02-06 Peloton Therapeutics, Inc. Cyclic sulfone and sulfoximine analogs and uses thereof
WO2016145045A1 (en) 2015-03-11 2016-09-15 Peloton Therapeutics, Inc. Compositions for use in treating glioblastoma
US10807948B2 (en) 2015-03-11 2020-10-20 Peloton Therapeutics, Inc. Aromatic compounds and uses thereof
US10278942B2 (en) 2015-03-11 2019-05-07 Peloton Therapeutics, Inc. Compositions for use in treating pulmonary arterial hypertension
WO2016144826A1 (en) 2015-03-11 2016-09-15 Peloton Therapeutics, Inc. Substituted pyridines and uses thereof
WO2016168510A1 (en) 2015-04-17 2016-10-20 Peloton Therapeutics, Inc. Combination therapy of a hif-2-alpha inhibitor and an immunotherapeutic agent and uses thereof
US9796697B2 (en) 2015-06-12 2017-10-24 Peloton Therapeutics, Inc. Tricyclic inhibitors of HIF-2-alpha and uses thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL160809C (nl) * 1970-05-15 1979-12-17 Duphar Int Res Werkwijze ter bereiding van benzoylureumverbindingen, alsmede werkwijze ter bereiding van insekticide prepara- ten op basis van benzoylureumverbindingen.
DE2059872A1 (de) * 1970-12-05 1972-06-15 Merck Patent Gmbh Thioharnstoffe,Verfahren zu ihrer Herstellung und ihre Verwendung zur Schaedlingsbekaempfung
US4160037A (en) * 1977-09-30 1979-07-03 The Upjohn Company Compounds, compositions and methods of combatting pest employing thioureas
ZA793186B (en) * 1978-07-06 1981-02-25 Duphar Int Res New urea and thiourea compounds, method of preparing the new compounds, as well as insecticidal compositions on the basis of these compounds
DE2837086A1 (de) * 1978-08-24 1980-03-06 Bayer Ag Substituierte n-phenyl-n'-benzoyl- thioharnstoffe, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
US4264605A (en) * 1978-08-31 1981-04-28 Eli Lilly And Company 1-Benzoyl-3-(aryloxy- or arylthiopyridinyl) urea compounds
GR73690B (de) * 1979-01-15 1984-04-02 Celamerck Gmbh & Co Kg
CA1138451A (en) * 1979-04-03 1982-12-28 Fujisawa Pharmaceutical Co., Ltd. 2-imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same
AU532156B2 (en) * 1979-09-07 1983-09-22 Ishihara Sangyo Kaisha Ltd. N-benzoyl-n'-pyridyloxy phenyl urea
US4426385A (en) * 1980-10-16 1984-01-17 Union Carbide Corporation Insecticidal bicyclooxyphenyl ureas
DE3161657D1 (en) * 1980-11-22 1984-01-19 Celamerck Gmbh & Co Kg Urea derivatives, preparation and use
US4468405A (en) * 1981-07-30 1984-08-28 The Dow Chemical Company Substituted N-aroyl N'-phenyl urea compounds
DE3217620A1 (de) * 1982-05-11 1983-11-17 Bayer Ag, 5090 Leverkusen 2,5-dihalogenbenzoyl-(thio)harnstoffe, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel

Also Published As

Publication number Publication date
US4665097A (en) 1987-05-12
EP0124282A1 (de) 1984-11-07
DE3466532D1 (en) 1987-11-05
DK173684A (da) 1984-10-01
JPS59184155A (ja) 1984-10-19
EP0124282B1 (de) 1987-09-30
DK173684D0 (da) 1984-03-30

Similar Documents

Publication Publication Date Title
DE3587568D1 (de) Diazepine enthaltende pharmazeutische Zusammensetzungen mit Plättchen aktivierender Faktor (PAF)-antagonistischer Wirkung.
ES2021266B3 (es) Nuevos derivados de quinazolina, procedimiento para su produccion y composiciones farmaceuticas que los contienen.
ATE86252T1 (de) Indolsaeureverbindungen und ihre anwendung als antiallergische heilmittel.
DE3466532D1 (en) Bicyclooxyaryl thioureas and process for preparation
MX9203165A (es) Derivados de succinimida y composicion farmaceutica que los contiene .
ATE37179T1 (de) Dihydropyridazinone.
CO5070570A1 (es) DERIVADOS DE TIROSINA COMO ACTIVADORES DE hPPAR Y hPPARalfa Y UNA COMPOSICION FARMACEUTICA QUE LOS CONTIENE
BG97221A (bg) Ортозаместени бифениламидини и бифенилизанидини и съдържащите ги антидиабетични или хипогликемични средства
ES546377A0 (es) Un procedimiento para la preparacion de oxindal-carboxamidas triciclicas.
ES2010284A6 (es) Procedimiento para preparar derivados de tiourea.
ES2000456A6 (es) Procedimiento para preparar deirvados de acido eicosatriinoico-5,8,11 y utilizacion de estos en composiciones farmaceuticas y cosmeticas.
ES2175405T3 (es) Derivados de adenosina.
ES450799A1 (es) Un procedimiento para la preparacion de nuevas 3-fenilespino(esobenzofuran-1,4&#39;-piperidemo) sulfenamidas y derivados.
GB1260386A (en) Trifluoromethyl-phenyl-ureas and pesticidal preparations containing them
ES548187A0 (es) Procedimiento para la preparacion de 1,4-dihidropiridina-hidroximina.
EP1144393A3 (de) Heterocyclische derivate und ihre verwendung als integrininhibitore
DE3877036D1 (de) Biologisch aktive verbindungen.
FI851308L (fi) Foerfarande foer framstaellning av nya 1,2,4-tiadiaziner.
ES2038159T3 (es) Procedimiento para preparar derivados sustituidos de 2-aminoacetamida.
DE3674546D1 (de) Amidderivate.
NZ501982A (en) N-oxide forms of 2,4,4-trisubstituted-1,3-dioxolane as anti-fungal agents
ES508257A0 (es) &#34;procedimiento para la preparacion de cetohidroxi-iminocefalosporinas&#34;.
DK389683A (da) Fremgangsmaade til fremstilling af substituerede 1,3,4-benzotriazepiner eller farmaceutisk acceptable syreadditionssalte deraf
IL63649A0 (en) Urea derivatives,their preparation and their use as fungicides
DK210387D0 (da) Heterocykliske forbindelser og fremgangsmaade til deres fremstilling samt farmaceutiske midler indeholdende disse

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee