ATE300542T1 - 1-glyoxlylamidindolizine zur behandlung von krebs - Google Patents

1-glyoxlylamidindolizine zur behandlung von krebs

Info

Publication number
ATE300542T1
ATE300542T1 AT02798231T AT02798231T ATE300542T1 AT E300542 T1 ATE300542 T1 AT E300542T1 AT 02798231 T AT02798231 T AT 02798231T AT 02798231 T AT02798231 T AT 02798231T AT E300542 T1 ATE300542 T1 AT E300542T1
Authority
AT
Austria
Prior art keywords
substituted
group
unsubstituted
independently
aryl group
Prior art date
Application number
AT02798231T
Other languages
English (en)
Inventor
Keizo Koya
Lijun Sun
Mitsunori Ono
Weiwen Ying
Hao Li
Original Assignee
Synta Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synta Pharmaceuticals Corp filed Critical Synta Pharmaceuticals Corp
Application granted granted Critical
Publication of ATE300542T1 publication Critical patent/ATE300542T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT02798231T 2001-09-13 2002-09-13 1-glyoxlylamidindolizine zur behandlung von krebs ATE300542T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32202001P 2001-09-13 2001-09-13
PCT/US2002/029154 WO2003022846A1 (en) 2001-09-13 2002-09-13 1-glyoxlylamide indolizines for treating cancer

Publications (1)

Publication Number Publication Date
ATE300542T1 true ATE300542T1 (de) 2005-08-15

Family

ID=23253054

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02798231T ATE300542T1 (de) 2001-09-13 2002-09-13 1-glyoxlylamidindolizine zur behandlung von krebs

Country Status (19)

Country Link
US (2) US6861436B2 (de)
EP (1) EP1432709B8 (de)
JP (1) JP2005504795A (de)
KR (1) KR20040053125A (de)
CN (1) CN1568324A (de)
AT (1) ATE300542T1 (de)
AU (1) AU2002333626B2 (de)
BR (1) BR0212794A (de)
CA (1) CA2459886A1 (de)
DE (1) DE60205265T2 (de)
ES (1) ES2245747T3 (de)
IL (1) IL160810A0 (de)
IS (1) IS7176A (de)
MX (1) MXPA04002323A (de)
NO (1) NO20041035L (de)
NZ (1) NZ531700A (de)
PT (1) PT1432709E (de)
WO (1) WO2003022846A1 (de)
ZA (1) ZA200401996B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2459886A1 (en) * 2001-09-13 2003-03-20 Synta Pharmaceuticals Corp. 1-glyoxlylamide indolizines for treating cancer
US20040116462A1 (en) * 2002-12-12 2004-06-17 Mitsunori Ono Indolizine compounds
WO2004024727A2 (en) * 2002-09-13 2004-03-25 Synta Pharmaceuticals Corp. Synthesis of indolizines
DE10318611A1 (de) 2003-04-24 2004-11-11 Elbion Ag 4-, 6- oder 7-Hydroxyindole mit N-Oxidgruppen und deren Verwendung als Therapeutika
WO2005099824A1 (en) * 2004-03-30 2005-10-27 Synta Pharmaceuticals, Corp. 1-glyoxylamide indolizines for treating lung and ovarian cancer
GB0413605D0 (en) 2004-06-17 2004-07-21 Addex Pharmaceuticals Sa Novel compounds
US20070293456A9 (en) * 2004-12-30 2007-12-20 Anthony Hayford Method for the synthesis of 3-substituted indolizine and benzoindolizine compounds
US20060293345A1 (en) * 2005-05-20 2006-12-28 Christoph Steeneck Heterobicyclic metalloprotease inhibitors
US20070155738A1 (en) * 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors
CA2733247C (en) * 2008-08-14 2018-04-03 Beta Pharma Canada Inc. Heterocyclic amide derivatives as ep4 receptor antagonists
CN104042617A (zh) 2009-04-29 2014-09-17 阿马里纳药物爱尔兰有限公司 含有epa和心血管剂的药物组合物以及使用其的方法
AR077428A1 (es) * 2009-07-29 2011-08-24 Sanofi Aventis (aza) indolizinacarboxamidas ciclicas su preparacion y su uso como agentes farmaceuticos
CN113603694B (zh) * 2021-07-16 2022-07-22 浙江工业大学 一种1,2-二酮类化合物及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2287706A (en) 1994-03-21 1995-09-27 Fujisawa Pharmaceutical Co Indolizine derivatives
FR2757166B1 (fr) * 1996-12-12 1999-01-29 Rhone Poulenc Rorer Sa Derives du pyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent
WO1998047507A1 (en) 1997-04-24 1998-10-29 Shionogi & Co., Ltd. Method for the treatment of stroke using n-heterocyclic glyoxylamide compounds
EP1085021A4 (de) 1998-05-21 2003-01-08 Shionogi & Co PYRROLO[1,2-B]PYRIDAZIN-DERIVATE MIT sPLA 2? HEMMENDEM EFFEKT
EP1157704B1 (de) 1998-10-14 2006-06-14 Shionogi & Co., Ltd. Spla2-inhibitoren zur behandlung von ischämischen reperfusionsschäden
US6461538B2 (en) * 1999-12-16 2002-10-08 Fuji Photo Film Co., Ltd. Production process for indolizine compounds and their use in organic light-emitting devices
US20040116462A1 (en) * 2002-12-12 2004-06-17 Mitsunori Ono Indolizine compounds
CA2459886A1 (en) * 2001-09-13 2003-03-20 Synta Pharmaceuticals Corp. 1-glyoxlylamide indolizines for treating cancer

Also Published As

Publication number Publication date
EP1432709B1 (de) 2005-07-27
WO2003022846A1 (en) 2003-03-20
MXPA04002323A (es) 2005-04-08
NZ531700A (en) 2006-10-27
US20030153759A1 (en) 2003-08-14
EP1432709B8 (de) 2005-11-02
NO20041035L (no) 2004-04-30
KR20040053125A (ko) 2004-06-23
IS7176A (is) 2004-03-11
AU2002333626B2 (en) 2006-06-29
ES2245747T3 (es) 2006-01-16
DE60205265T2 (de) 2006-03-30
IL160810A0 (en) 2004-08-31
CN1568324A (zh) 2005-01-19
JP2005504795A (ja) 2005-02-17
US20040214850A1 (en) 2004-10-28
EP1432709A1 (de) 2004-06-30
CA2459886A1 (en) 2003-03-20
PT1432709E (pt) 2005-10-31
ZA200401996B (en) 2005-05-31
BR0212794A (pt) 2004-10-05
DE60205265D1 (de) 2005-09-01
US6861436B2 (en) 2005-03-01
HK1063322A1 (en) 2004-12-24

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