ATE300612T1 - Theta-untereinheit des menschlichen gaba-a rezeptors - Google Patents

Theta-untereinheit des menschlichen gaba-a rezeptors

Info

Publication number
ATE300612T1
ATE300612T1 AT98917470T AT98917470T ATE300612T1 AT E300612 T1 ATE300612 T1 AT E300612T1 AT 98917470 T AT98917470 T AT 98917470T AT 98917470 T AT98917470 T AT 98917470T AT E300612 T1 ATE300612 T1 AT E300612T1
Authority
AT
Austria
Prior art keywords
receptor
human gaba
theta subunit
cell line
subunit
Prior art date
Application number
AT98917470T
Other languages
English (en)
Inventor
Timothy Peter Bonnert
Paul John Whiting
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE300612T1 publication Critical patent/ATE300612T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Radio Relay Systems (AREA)
AT98917470T 1997-04-25 1998-04-24 Theta-untereinheit des menschlichen gaba-a rezeptors ATE300612T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9708479.2A GB9708479D0 (en) 1997-04-25 1997-04-25 Nucleic acids
PCT/GB1998/001206 WO1998049293A1 (en) 1997-04-25 1998-04-24 Human theta subunit of the gaba-a receptor

Publications (1)

Publication Number Publication Date
ATE300612T1 true ATE300612T1 (de) 2005-08-15

Family

ID=10811405

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98917470T ATE300612T1 (de) 1997-04-25 1998-04-24 Theta-untereinheit des menschlichen gaba-a rezeptors

Country Status (11)

Country Link
US (1) US6555341B1 (de)
EP (1) EP0977848B1 (de)
JP (1) JP2002501382A (de)
AT (1) ATE300612T1 (de)
AU (1) AU7069498A (de)
CA (1) CA2287782A1 (de)
DE (1) DE69830989T2 (de)
DK (1) DK0977848T3 (de)
ES (1) ES2244057T3 (de)
GB (1) GB9708479D0 (de)
WO (1) WO1998049293A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1500703A3 (de) * 2000-06-27 2005-02-16 Lexicon Genetics Incorporated Menschliche Gaba-rezeptoren und für diese kodierende Polynukleotide
AU7151601A (en) 2000-06-27 2002-01-08 Lexicon Genetics Inc Novel human gaba receptors and polynucleotides encoding the same
WO2007002359A2 (en) * 2005-06-24 2007-01-04 The Regents Of The University Of California Methods for identifying delta subunit-containing gaba receptor modulatory agents
NZ601353A (en) * 2008-02-01 2014-06-27 Chromocell Corp Cell lines and methods for making and using them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994013799A1 (en) 1992-12-10 1994-06-23 Merck Sharp & Dohme Limited Stably transfected cell lines expressing gaba-a receptors
GB9408064D0 (en) 1994-04-22 1994-06-15 Merck Sharp & Dohme Nucleic acids

Also Published As

Publication number Publication date
US6555341B1 (en) 2003-04-29
DE69830989D1 (de) 2005-09-01
JP2002501382A (ja) 2002-01-15
DK0977848T3 (da) 2005-11-14
EP0977848B1 (de) 2005-07-27
DE69830989T2 (de) 2006-04-20
ES2244057T3 (es) 2005-12-01
WO1998049293A1 (en) 1998-11-05
EP0977848A1 (de) 2000-02-09
GB9708479D0 (en) 1997-06-18
CA2287782A1 (en) 1998-11-05
AU7069498A (en) 1998-11-24

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Legal Events

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