ATE301469T1 - Pharmazeutische diclofenac-verbindung basierend auf vitamin e, papain und hyaluronidase - Google Patents
Pharmazeutische diclofenac-verbindung basierend auf vitamin e, papain und hyaluronidaseInfo
- Publication number
- ATE301469T1 ATE301469T1 AT01913407T AT01913407T ATE301469T1 AT E301469 T1 ATE301469 T1 AT E301469T1 AT 01913407 T AT01913407 T AT 01913407T AT 01913407 T AT01913407 T AT 01913407T AT E301469 T1 ATE301469 T1 AT E301469T1
- Authority
- AT
- Austria
- Prior art keywords
- hyaluronidase
- papain
- vitamin
- pharmaceutical
- compound based
- Prior art date
Links
- 108010003272 Hyaluronate lyase Proteins 0.000 title abstract 2
- 102000001974 Hyaluronidases Human genes 0.000 title abstract 2
- 229960001259 diclofenac Drugs 0.000 title abstract 2
- 229960002773 hyaluronidase Drugs 0.000 title abstract 2
- 229940088594 vitamin Drugs 0.000 title abstract 2
- 229930003231 vitamin Natural products 0.000 title abstract 2
- 235000013343 vitamin Nutrition 0.000 title abstract 2
- 239000011782 vitamin Substances 0.000 title abstract 2
- 150000003722 vitamin derivatives Chemical class 0.000 title abstract 2
- -1 DICLOFENAC COMPOUND Chemical class 0.000 title 1
- 108090000526 Papain Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940055729 papain Drugs 0.000 abstract 1
- 235000019834 papain Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/51—Lyases (4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0001144-4B1A BR0001144B1 (pt) | 2000-02-21 | 2000-02-21 | Composicão farmacêutica de diclofenaco à base de vitamina-e, papaína e hialuronidase |
| PCT/BR2001/000019 WO2001060399A1 (en) | 2000-02-21 | 2001-02-20 | Diclofenac pharmaceutical composition based on vitamin-e, papain and hyaluronidase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE301469T1 true ATE301469T1 (de) | 2005-08-15 |
Family
ID=3943888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01913407T ATE301469T1 (de) | 2000-02-21 | 2001-02-20 | Pharmazeutische diclofenac-verbindung basierend auf vitamin e, papain und hyaluronidase |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20030103955A1 (de) |
| EP (1) | EP1299114B1 (de) |
| AT (1) | ATE301469T1 (de) |
| AU (1) | AU3903701A (de) |
| BR (1) | BR0001144B1 (de) |
| CA (1) | CA2399219C (de) |
| DE (1) | DE60112578T2 (de) |
| ES (1) | ES2244591T3 (de) |
| MX (1) | MXPA02008116A (de) |
| PT (1) | PT1299114E (de) |
| WO (1) | WO2001060399A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0000426B1 (pt) * | 2000-01-28 | 2014-09-30 | Biolab Sanus Farmaceutica Ltda | Composição farmacêutica |
| BR0006719A (pt) * | 2000-05-04 | 2001-09-25 | Cristiano Alberto Ribeiro Sant | Composição em forma de creme, gel e creme gel aplicada na terapêutica da doença de peyronie, de colagenoses e patologias fibróticas à base de vitamina-e, papaìna 2% e hialuronidase |
| WO2003018063A1 (en) * | 2001-08-27 | 2003-03-06 | Medtopic Empreendimentos E Particapações S/C Ltda. | Composition of a carrier substance for products based on papain and hyaluronidase |
| ES2223277B1 (es) * | 2003-06-19 | 2006-03-01 | Fernando Bouffard Fita | Composicion anestesica para administracion topica. |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2448903A1 (fr) * | 1979-02-19 | 1980-09-12 | Martin Henri | Medicament nouveau a base d'agents antimicrobiens, d'enzymes, d'anti-inflammatoires, d'anesthesique local, d'agents keratolytiques, d'agents mucolytiques et d'au moins un emulsionnant |
| US4855142A (en) * | 1987-02-27 | 1989-08-08 | Ciba-Geigy Corporation | Pharmaceutical plaster |
| US5296222A (en) * | 1989-02-23 | 1994-03-22 | University Of Utah | Percutaneous drug delivery system |
| US5242391A (en) * | 1990-04-25 | 1993-09-07 | Alza Corporation | Urethral insert for treatment of erectile dysfunction |
| JP3765579B2 (ja) * | 1990-08-24 | 2006-04-12 | イーデーエーアー アーゲー | 作用物質投与用超微小滴状調剤 |
| US6165500A (en) * | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
| DK42093D0 (da) * | 1993-04-07 | 1993-04-07 | Bukh Meditec | Administrationsmetode |
| DE4313402A1 (de) * | 1993-04-23 | 1994-10-27 | Hexal Pharma Gmbh | Transdermale Wirkstoffzubereitung |
| US5795916A (en) * | 1994-08-09 | 1998-08-18 | Tsumura & Co. | Composition of external preparation |
-
2000
- 2000-02-21 BR BRPI0001144-4B1A patent/BR0001144B1/pt not_active IP Right Cessation
-
2001
- 2001-02-20 PT PT01913407T patent/PT1299114E/pt unknown
- 2001-02-20 AU AU39037/01A patent/AU3903701A/en not_active Abandoned
- 2001-02-20 ES ES01913407T patent/ES2244591T3/es not_active Expired - Lifetime
- 2001-02-20 EP EP01913407A patent/EP1299114B1/de not_active Expired - Lifetime
- 2001-02-20 CA CA2399219A patent/CA2399219C/en not_active Expired - Fee Related
- 2001-02-20 US US10/204,464 patent/US20030103955A1/en not_active Abandoned
- 2001-02-20 DE DE60112578T patent/DE60112578T2/de not_active Expired - Lifetime
- 2001-02-20 WO PCT/BR2001/000019 patent/WO2001060399A1/en not_active Ceased
- 2001-02-20 MX MXPA02008116A patent/MXPA02008116A/es active IP Right Grant
- 2001-02-20 AT AT01913407T patent/ATE301469T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BR0001144B1 (pt) | 2013-10-22 |
| PT1299114E (pt) | 2005-11-30 |
| US20030103955A1 (en) | 2003-06-05 |
| DE60112578T2 (de) | 2006-05-24 |
| AU3903701A (en) | 2001-08-27 |
| DE60112578D1 (de) | 2005-09-15 |
| EP1299114B1 (de) | 2005-08-10 |
| CA2399219A1 (en) | 2001-08-23 |
| MXPA02008116A (es) | 2004-06-29 |
| EP1299114A1 (de) | 2003-04-09 |
| ES2244591T3 (es) | 2005-12-16 |
| CA2399219C (en) | 2013-04-09 |
| BR0001144A (pt) | 2001-11-27 |
| WO2001060399A1 (en) | 2001-08-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1299114 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |