ATE302199T1 - Quinalozinon-derivate - Google Patents
Quinalozinon-derivateInfo
- Publication number
- ATE302199T1 ATE302199T1 AT99970659T AT99970659T ATE302199T1 AT E302199 T1 ATE302199 T1 AT E302199T1 AT 99970659 T AT99970659 T AT 99970659T AT 99970659 T AT99970659 T AT 99970659T AT E302199 T1 ATE302199 T1 AT E302199T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen atom
- alkyl group
- äwherein
- chem
- group
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 102000014415 Muscarinic acetylcholine receptor Human genes 0.000 abstract 1
- 108050003473 Muscarinic acetylcholine receptor Proteins 0.000 abstract 1
- 206010036018 Pollakiuria Diseases 0.000 abstract 1
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000001078 anti-cholinergic effect Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Chemical group 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP29505098 | 1998-10-16 | ||
| PCT/JP1999/005560 WO2000023436A1 (en) | 1998-10-16 | 1999-10-07 | Quinazolinone derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE302199T1 true ATE302199T1 (de) | 2005-09-15 |
Family
ID=17815680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99970659T ATE302199T1 (de) | 1998-10-16 | 1999-10-07 | Quinalozinon-derivate |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6645971B1 (de) |
| EP (1) | EP1122253B1 (de) |
| JP (1) | JP4484368B2 (de) |
| KR (1) | KR100607634B1 (de) |
| AT (1) | ATE302199T1 (de) |
| CA (1) | CA2347506C (de) |
| DE (1) | DE69926776T2 (de) |
| ES (1) | ES2244243T3 (de) |
| PT (1) | PT1122253E (de) |
| WO (1) | WO2000023436A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1424334T3 (da) | 2001-08-09 | 2008-02-11 | Dainippon Sumitomo Pharma Co | Quinazolinonderivat |
| JP2007516292A (ja) * | 2003-12-23 | 2007-06-21 | ダーファーマ，インコーポレイテッド | ドーパミン受容体結合化合物の共投与 |
| JP4643948B2 (ja) * | 2004-08-23 | 2011-03-02 | 大日本住友製薬株式会社 | キナゾリノン化合物の安定化方法 |
| JP4667789B2 (ja) * | 2004-08-23 | 2011-04-13 | 大日本住友製薬株式会社 | キナゾリノン化合物の酸付加塩の製造方法 |
| US20090275574A1 (en) * | 2008-05-05 | 2009-11-05 | Astrazeneca Ab | Novel compounds-300 |
| PE20120031A1 (es) | 2008-11-20 | 2012-02-05 | Merck Sharp & Dohme | Compuestos aril metil benzoquinazolinona como moduladores alostericos positivos del receptor m1 |
| EP2512245B1 (de) * | 2009-12-14 | 2014-07-23 | Merck Sharp & Dohme Corp. | Positive allosterische pyridochinolizidinon-m1-rezeptormodulatoren |
| US8383638B2 (en) * | 2009-12-21 | 2013-02-26 | Merck Sharp & Dohme | Aminobenzoquinazolinone M1 receptor positive allosteric modulators |
| US11739070B2 (en) | 2018-01-19 | 2023-08-29 | Idorsia Pharmaceuticals Ltd. | C5A receptor modulators |
| JP7281470B2 (ja) * | 2018-01-19 | 2023-05-25 | イドーシア ファーマシューティカルズ リミテッド | Ｃ５ａ受容体調節剤 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4822716B1 (de) * | 1968-07-01 | 1973-07-07 | ||
| US3819627A (en) * | 1968-07-01 | 1974-06-25 | Sandoz Ag | 1-substituted-3,4-dihydro-2(1h)-quinazolinones |
| FR2027023A1 (en) * | 1968-12-24 | 1970-09-25 | Farmaceutici Italia | Substd quinazoline derivs prepn cns depress - ants |
| US3547921A (en) | 1968-12-26 | 1970-12-15 | Sandoz Ag | Preparation of 1-substituted-4-aryl-3,4-dihydro-2(1h)-quinazolinones |
| JPS4834598B1 (de) | 1970-12-23 | 1973-10-22 | ||
| US3829420A (en) | 1970-07-13 | 1974-08-13 | Sumitomo Chemical Co | 3,4-dihydro-2(1h)-quinazolinones and preparation thereof |
| US4099002A (en) | 1970-12-23 | 1978-07-04 | Sumitomo Chemical Company, Limited | Quinazolinone derivatives and a process for production thereof |
| AU438472B2 (en) * | 1970-12-23 | 1973-08-09 | Sumitomo Chemical Company, Limited | Quinazolinone derivatives anda process for production thereof |
| BE795519A (fr) * | 1972-02-18 | 1973-06-18 | Sumitomo Chemical Co | Procede de preparation d'un agent uricosurique |
| US3812257A (en) * | 1972-04-07 | 1974-05-21 | Sumitomo Chemical Co | Uricosuric agent |
| JPS4925270B1 (de) * | 1973-04-09 | 1974-06-28 | ||
| US4335127A (en) * | 1979-01-08 | 1982-06-15 | Janssen Pharmaceutica, N.V. | Piperidinylalkyl quinazoline compounds, composition and method of use |
| JPS56113769A (en) * | 1980-02-13 | 1981-09-07 | Sumitomo Chem Co Ltd | Novel 2 1h -quinazolinone derivative and its preparation |
| JPS5795966A (en) * | 1980-12-04 | 1982-06-15 | Sumitomo Chem Co Ltd | Novel 2(1h)-quinazolinone derivative |
| EP0626373B1 (de) | 1993-05-26 | 1998-12-23 | Sumitomo Pharmaceuticals Company, Limited | Chinazolinonderivate |
| JP3859738B2 (ja) | 1993-05-26 | 2006-12-20 | 大日本住友製薬株式会社 | キナゾリノン誘導体 |
-
1999
- 1999-10-07 ES ES99970659T patent/ES2244243T3/es not_active Expired - Lifetime
- 1999-10-07 AT AT99970659T patent/ATE302199T1/de active
- 1999-10-07 US US09/807,173 patent/US6645971B1/en not_active Expired - Fee Related
- 1999-10-07 EP EP99970659A patent/EP1122253B1/de not_active Expired - Lifetime
- 1999-10-07 KR KR1020017004718A patent/KR100607634B1/ko not_active Expired - Fee Related
- 1999-10-07 CA CA002347506A patent/CA2347506C/en not_active Expired - Fee Related
- 1999-10-07 DE DE69926776T patent/DE69926776T2/de not_active Expired - Lifetime
- 1999-10-07 WO PCT/JP1999/005560 patent/WO2000023436A1/ja not_active Ceased
- 1999-10-07 PT PT99970659T patent/PT1122253E/pt unknown
- 1999-10-07 JP JP2000577163A patent/JP4484368B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| PT1122253E (pt) | 2005-11-30 |
| DE69926776D1 (de) | 2005-09-22 |
| DE69926776T2 (de) | 2006-06-08 |
| EP1122253A4 (de) | 2003-05-28 |
| JP4484368B2 (ja) | 2010-06-16 |
| WO2000023436A1 (en) | 2000-04-27 |
| US6645971B1 (en) | 2003-11-11 |
| CA2347506A1 (en) | 2000-04-27 |
| CA2347506C (en) | 2009-06-23 |
| ES2244243T3 (es) | 2005-12-01 |
| EP1122253B1 (de) | 2005-08-17 |
| EP1122253A1 (de) | 2001-08-08 |
| KR20010080159A (ko) | 2001-08-22 |
| KR100607634B1 (ko) | 2006-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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