ATE303801T1 - Retinoid-formulierungen zur aerosolbildung und zur inhalation - Google Patents

Retinoid-formulierungen zur aerosolbildung und zur inhalation

Info

Publication number: ATE303801T1
Authority: AT; Austria
Prior art keywords: inhalation; aerosol formation; formulations; retinoid formulations; retinoid
Prior art date: 2000-03-07

Application number

AT01918375T

Other languages

English (en)

Inventor

Alan R Dahl

Michael E Placke

William C Zimlich Jr

Luca Luigi M De

James L Mulshine

Original Assignee

Battelle Memorial Institute

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-07

Filing date

2001-03-07

Publication date

2005-09-15

2001-03-07 Application filed by Battelle Memorial Institute filed Critical Battelle Memorial Institute

2005-09-15 Application granted granted Critical

2005-09-15 Publication of ATE303801T1 publication Critical patent/ATE303801T1/de

Links

239000000443 aerosol Substances 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
230000015572 biosynthetic process Effects 0.000 title 1
150000004492 retinoid derivatives Chemical class 0.000 title 1
SHGAZHPCJJPHSC-NUEINMDLSA-N Isotretinoin Chemical compound OC(=O)C=C(C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-NUEINMDLSA-N 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
210000004072 lung Anatomy 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000009826 neoplastic cell growth Effects 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Otolaryngology (AREA)
Pulmonology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Dispersion Chemistry (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT01918375T 2000-03-07 2001-03-07 Retinoid-formulierungen zur aerosolbildung und zur inhalation ATE303801T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US18753900P	2000-03-07	2000-03-07
PCT/US2001/007123 WO2001066104A2 (en)	2000-03-07	2001-03-07	Retinoid formulations for aerosolization and inhalation

Publications (1)

Publication Number	Publication Date
ATE303801T1 true ATE303801T1 (de)	2005-09-15

Family

ID=22689393

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01918375T ATE303801T1 (de)	2000-03-07	2001-03-07	Retinoid-formulierungen zur aerosolbildung und zur inhalation

Country Status (5)

Country	Link
EP (1)	EP1263420B1 (de)
AT (1)	ATE303801T1 (de)
AU (1)	AU2001245459A1 (de)
DE (1)	DE60113240T2 (de)
WO (1)	WO2001066104A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20080038738A1 (en) *	2006-05-10	2008-02-14	The Board Of Regents Of The University Of Texas System	Detecting tumor biomarker in oral cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0003064A3 (de) *	1977-12-07	1979-08-08	Rabam Limited	Verfahren zum Einführen von Vitamin A-Analogen in die Atemwege eines Zigarettenrauchers
DE3815221C2 (de) *	1988-05-04	1995-06-29	Gradinger F Hermes Pharma	Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen
US6251941B1 (en) *	1996-04-19	2001-06-26	Sloan-Kettering Institute For Cancer Research	Use of inhaled retinoids in the prevention of cancer
EP1239745A1 (de) *	1999-08-11	2002-09-18	Therapeutics 2000, Inc.	Antioxidans-inhalator und korrespondierendes verfahren

2001
- 2001-03-07 WO PCT/US2001/007123 patent/WO2001066104A2/en not_active Ceased
- 2001-03-07 AT AT01918375T patent/ATE303801T1/de not_active IP Right Cessation
- 2001-03-07 DE DE60113240T patent/DE60113240T2/de not_active Expired - Fee Related
- 2001-03-07 EP EP01918375A patent/EP1263420B1/de not_active Expired - Lifetime
- 2001-03-07 AU AU2001245459A patent/AU2001245459A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE60113240T2 (de)	2006-06-29
WO2001066104A3 (en)	2002-01-24
EP1263420B1 (de)	2005-09-07
AU2001245459A1 (en)	2001-09-17
WO2001066104A2 (en)	2001-09-13
EP1263420A2 (de)	2002-12-11
DE60113240D1 (de)	2005-10-13

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Legal Events

Date	Code	Title	Description
2006-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties