ATE304021T1 - Lektin-ähnliche domäne von thrombomodulin und therapeutische verwendung davon - Google Patents

Lektin-ähnliche domäne von thrombomodulin und therapeutische verwendung davon

Info

Publication number: ATE304021T1
Authority: AT; Austria
Prior art keywords: domain; lectin; thrombomodulin; meaning; inflammatory
Prior art date: 2001-05-25

Application number

AT02738105T

Other languages

English (en)

Inventor

Edward M Conway

Desire Collen

Original Assignee

Vlaams Interuniv Inst Biotech

D Collen Res Foundation Vzw

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-25

Filing date

2002-05-24

Publication date

2005-09-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8180374&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE304021(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-05-24 Application filed by Vlaams Interuniv Inst Biotech, D Collen Res Foundation Vzw filed Critical Vlaams Interuniv Inst Biotech

2005-09-15 Application granted granted Critical

2005-09-15 Publication of ATE304021T1 publication Critical patent/ATE304021T1/de

Links

102000012607 Thrombomodulin Human genes 0.000 title abstract 3
108010079274 Thrombomodulin Proteins 0.000 title abstract 3
230000000503 lectinlike effect Effects 0.000 title abstract 3
230000001225 therapeutic effect Effects 0.000 title 1
241000699670 Mus sp. Species 0.000 abstract 3
206010015866 Extravasation Diseases 0.000 abstract 1
241001529936 Murinae Species 0.000 abstract 1
101800004937 Protein C Proteins 0.000 abstract 1
102100036546 Salivary acidic proline-rich phosphoprotein 1/2 Human genes 0.000 abstract 1
101800001700 Saposin-D Proteins 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
230000036251 extravasation Effects 0.000 abstract 1
230000006801 homologous recombination Effects 0.000 abstract 1
238000002744 homologous recombination Methods 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
230000002757 inflammatory effect Effects 0.000 abstract 1
230000023404 leukocyte cell-cell adhesion Effects 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000035772 mutation Effects 0.000 abstract 1
210000000440 neutrophil Anatomy 0.000 abstract 1
210000000056 organ Anatomy 0.000 abstract 1
230000037361 pathway Effects 0.000 abstract 1
239000003805 procoagulant Substances 0.000 abstract 1
229960000856 protein c Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/7455—Thrombomodulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AT02738105T 2001-05-25 2002-05-24 Lektin-ähnliche domäne von thrombomodulin und therapeutische verwendung davon ATE304021T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01201979		2001-05-25
PCT/EP2002/005727 WO2002096947A2 (en)	2001-05-25	2002-05-24	The lectin-like domain of thrombomodulin and its therapeutic use

Publications (1)

Publication Number	Publication Date
ATE304021T1 true ATE304021T1 (de)	2005-09-15

Family

ID=8180374

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02738105T ATE304021T1 (de)	2001-05-25	2002-05-24	Lektin-ähnliche domäne von thrombomodulin und therapeutische verwendung davon

Country Status (7)

Country	Link
US (1)	US7341992B2 (de)
EP (1)	EP1390407B1 (de)
AT (1)	ATE304021T1 (de)
CA (1)	CA2447629A1 (de)
DE (1)	DE60206037T2 (de)
ES (1)	ES2249586T3 (de)
WO (1)	WO2002096947A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE304021T1 (de)	2001-05-25	2005-09-15	Vlaams Interuniv Inst Biotech	Lektin-ähnliche domäne von thrombomodulin und therapeutische verwendung davon
US20060148695A1 (en) *	2005-01-03	2006-07-06	National Cheng Kung University	Novel angiogenic composition and use thereof
AR067345A1 (es) *	2007-07-10	2009-10-07	Paion Deutschland Gmbh	Uso de trombomodulina para la preparacion de un medicamento trombolitico
EP2014296A1 (de) *	2007-07-10	2009-01-14	PAION Deutschland GmbH	Neuartige Strategien zur Erhöhung der Reperfusion in einem verstopften Blutgefäß
US20100113568A1 (en) *	2008-10-30	2010-05-06	Hua-Lin Wu	Methods for binding lewis y antigen
US20120165244A1 (en) *	2008-10-30	2012-06-28	Hua-Lin Wu	Methods for binding lewis y antigen
US9775885B2 (en) *	2016-01-29	2017-10-03	Kaohsiung Medical Univeristy	TMD1 protein for treating bone loss diseases
US11895994B2 (en)	2019-10-27	2024-02-13	Shanghai Raas Blood Products Co., Ltd.	Humanized knock-in mouse expressing human Protein C
CN111296364B (zh) *	2019-10-27	2022-06-24	上海莱士血液制品股份有限公司	一种基因改造的小鼠动物模型基因改造方法及其应用
US11338019B2 (en) *	2020-05-24	2022-05-24	Yi-Hsun Huang	Recombinant thrombomodulin domain 1 for use in treating eye diseases associated with pathological ocular angiogenesis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4912207A (en) *	1987-05-06	1990-03-27	Washington University	DNA clone of human thrombomodulin and portions thereof
CA2065409C (en) *	1990-06-27	2002-05-14	Mochida Pharmaceutical Co., Ltd.	Anticoagulant polypeptides
WO1998029453A1 (en) *	1996-12-27	1998-07-09	Mochida Pharmaceutical Co., Ltd.	Cell membrane-directed drugs
JP4256497B2 (ja) *	1998-08-06	2009-04-22	旭化成ファーマ株式会社	血管炎治療剤
DE10106852A1 (de) *	2001-02-14	2002-09-05	T Luger	Entzündungshemmende Verbindungen
ATE304021T1 (de)	2001-05-25	2005-09-15	Vlaams Interuniv Inst Biotech	Lektin-ähnliche domäne von thrombomodulin und therapeutische verwendung davon

2002
- 2002-05-24 AT AT02738105T patent/ATE304021T1/de active
- 2002-05-24 US US10/478,360 patent/US7341992B2/en not_active Expired - Fee Related
- 2002-05-24 WO PCT/EP2002/005727 patent/WO2002096947A2/en not_active Ceased
- 2002-05-24 CA CA002447629A patent/CA2447629A1/en not_active Abandoned
- 2002-05-24 ES ES02738105T patent/ES2249586T3/es not_active Expired - Lifetime
- 2002-05-24 EP EP02738105A patent/EP1390407B1/de not_active Expired - Lifetime
- 2002-05-24 DE DE60206037T patent/DE60206037T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE60206037T2 (de)	2006-07-13
US20050014220A1 (en)	2005-01-20
WO2002096947A3 (en)	2003-09-04
WO2002096947A2 (en)	2002-12-05
CA2447629A1 (en)	2002-12-05
DE60206037D1 (de)	2005-10-13
ES2249586T3 (es)	2006-04-01
EP1390407A2 (de)	2004-02-25
US7341992B2 (en)	2008-03-11
WO2002096947A8 (en)	2003-02-13
EP1390407B1 (de)	2005-09-07

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2006-11-15

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