ATE304047T1 - Verbesserte methoden um säugetierzellen in vitro zu züchten - Google Patents

Verbesserte methoden um säugetierzellen in vitro zu züchten

Info

Publication number
ATE304047T1
ATE304047T1 AT03004806T AT03004806T ATE304047T1 AT E304047 T1 ATE304047 T1 AT E304047T1 AT 03004806 T AT03004806 T AT 03004806T AT 03004806 T AT03004806 T AT 03004806T AT E304047 T1 ATE304047 T1 AT E304047T1
Authority
AT
Austria
Prior art keywords
vitro
improved methods
mammal cells
citrate
growing
Prior art date
Application number
AT03004806T
Other languages
English (en)
Inventor
Ulrich Behrendt
Horst Eberhardt
Berthold Szperalski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27798778&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE304047(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Application granted granted Critical
Publication of ATE304047T1 publication Critical patent/ATE304047T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT03004806T 2002-03-05 2003-03-04 Verbesserte methoden um säugetierzellen in vitro zu züchten ATE304047T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02004366 2002-03-05

Publications (1)

Publication Number Publication Date
ATE304047T1 true ATE304047T1 (de) 2005-09-15

Family

ID=27798778

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03004806T ATE304047T1 (de) 2002-03-05 2003-03-04 Verbesserte methoden um säugetierzellen in vitro zu züchten

Country Status (11)

Country Link
US (1) US7390660B2 (de)
EP (1) EP1342780B1 (de)
JP (2) JP4476554B2 (de)
KR (1) KR100576589B1 (de)
CN (1) CN100398640C (de)
AT (1) ATE304047T1 (de)
CA (1) CA2417689C (de)
DE (1) DE60301510T2 (de)
DK (1) DK1342780T3 (de)
ES (1) ES2248657T3 (de)
MX (1) MXPA03001487A (de)

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KR20130101161A (ko) * 2005-01-05 2013-09-12 추가이 세이야쿠 가부시키가이샤 세포의 배양 방법 및 그 이용
DE102005046225B4 (de) * 2005-09-28 2012-01-05 Cellca Gmbh Verbessertes Zellkulturmedium
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
NZ597334A (en) 2006-09-13 2014-02-28 Abbott Lab Cell culture improvements
TW200902708A (en) 2007-04-23 2009-01-16 Wyeth Corp Methods of protein production using anti-senescence compounds
WO2009023562A2 (en) * 2007-08-09 2009-02-19 Wyeth Use of perfusion to enhance production of fed-batch cell culture in bioreactors
MX2011004201A (es) 2008-10-20 2011-05-24 Abbott Lab Desactivacion viral durante purificacion de anticuerpos.
AU2009347206C1 (en) 2008-10-20 2016-12-08 Abbvie Inc. Isolation and purification of antibodies using Protein A affinity chromatography
HUE067718T2 (hu) 2009-10-26 2024-11-28 Hoffmann La Roche Eljárás glikozilált immunglobulin elõállítására
JP5882913B2 (ja) 2010-12-27 2016-03-09 協和発酵キリン株式会社 培地およびキレート剤を含む水溶液の調製方法
EP2702077A2 (de) 2011-04-27 2014-03-05 AbbVie Inc. Verfahren zur steuerung des galactosylierungsprofil von rekombinant exprimierten proteinen
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9334319B2 (en) 2012-04-20 2016-05-10 Abbvie Inc. Low acidic species compositions
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
KR20150043523A (ko) 2012-09-02 2015-04-22 애브비 인코포레이티드 단백질 불균일성의 제어 방법
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
WO2014143205A1 (en) 2013-03-12 2014-09-18 Abbvie Inc. Human antibodies that bind human tnf-alpha and methods of preparing the same
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
US9499614B2 (en) 2013-03-14 2016-11-22 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
US8921526B2 (en) 2013-03-14 2014-12-30 Abbvie, Inc. Mutated anti-TNFα antibodies and methods of their use
WO2015051293A2 (en) 2013-10-04 2015-04-09 Abbvie, Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US11390663B2 (en) 2013-10-11 2022-07-19 Regeneron Pharmaceuticals, Inc. Metabolically optimized cell culture
JP6663854B2 (ja) 2013-10-11 2020-03-13 リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. 代謝が最適化された細胞培養
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
KR20160127822A (ko) 2014-04-07 2016-11-04 도요세이칸 그룹 홀딩스 가부시키가이샤 동물 세포용 배양액 및 배양 용기
CA3253362A1 (en) 2022-03-02 2023-09-07 Regeneron Pharmaceuticals, Inc. PROCESS FOR MANUFACTURED HIGH-TITLE ANTIBODY
WO2025209979A1 (en) 2024-04-04 2025-10-09 Roche Diagnostics Gmbh METHOD FOR PRODUCING RECOMBINANT VIRUSES OR VIRUS-LIKE PARTICLES (VLPs) IN MAMMALIAN CELL LINES

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
US5328844A (en) 1990-05-09 1994-07-12 University Of Colorado Foundation, Inc. Culture media for mammalian cells
WO1993000423A1 (en) 1991-06-21 1993-01-07 Novo Nordisk A/S Iron chelate culture medium additive
JP3046415B2 (ja) * 1991-10-04 2000-05-29 日水製薬株式会社 浮遊細胞用無血清合成培地
JPH0870858A (ja) * 1993-12-24 1996-03-19 Eiken Chem Co Ltd 動物細胞培養用培地
US5719050A (en) * 1993-12-24 1998-02-17 Eiken Chemical Co., Ltd. Animal cell culturing media containing N-acetyl-L-glutamic acid
US5856179A (en) * 1994-03-10 1999-01-05 Genentech, Inc. Polypeptide production in animal cell culture
WO1998041611A1 (en) 1997-03-20 1998-09-24 Regents Of The University Of Minnesota Process for the continuous culture of cells
UA74557C2 (en) * 1999-09-03 2006-01-16 Applied Research Systems A method for producing a heterologous secreted protein from chinese hamster ovaries cells grown on microcarriers
US6762053B2 (en) * 2000-06-09 2004-07-13 Vitrolife, Inc. Mammalian gamete and embryo culture media and culture media supplements
CA2438148A1 (en) * 2001-02-15 2002-08-29 Centocor, Inc. Chemically defined medium for cultured mammalian cells

Also Published As

Publication number Publication date
CA2417689C (en) 2006-05-09
CN100398640C (zh) 2008-07-02
JP4476554B2 (ja) 2010-06-09
JP5191970B2 (ja) 2013-05-08
CN1442478A (zh) 2003-09-17
KR100576589B1 (ko) 2006-05-04
JP2003250533A (ja) 2003-09-09
DK1342780T3 (da) 2005-12-12
KR20030074204A (ko) 2003-09-19
JP2010000094A (ja) 2010-01-07
US20030175951A1 (en) 2003-09-18
DE60301510T2 (de) 2006-06-14
CA2417689A1 (en) 2003-09-05
US7390660B2 (en) 2008-06-24
DE60301510D1 (de) 2005-10-13
ES2248657T3 (es) 2006-03-16
EP1342780A1 (de) 2003-09-10
EP1342780B1 (de) 2005-09-07
MXPA03001487A (es) 2005-09-08

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