ATE304047T1 - Verbesserte methoden um säugetierzellen in vitro zu züchten - Google Patents

Verbesserte methoden um säugetierzellen in vitro zu züchten

Info

Publication number: ATE304047T1
Authority: AT; Austria
Prior art keywords: vitro; improved methods; mammal cells; citrate; growing
Prior art date: 2002-03-05

Application number

AT03004806T

Other languages

English (en)

Inventor

Ulrich Behrendt

Horst Eberhardt

Berthold Szperalski

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-05

Filing date

2003-03-04

Publication date

2005-09-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27798778&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE304047(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-03-04 Application filed filed Critical

2005-09-15 Application granted granted Critical

2005-09-15 Publication of ATE304047T1 publication Critical patent/ATE304047T1/de

Links

238000000034 method Methods 0.000 title abstract 2
241000124008 Mammalia Species 0.000 title 1
238000000338 in vitro Methods 0.000 title 1
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 6
KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 2
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
SYHPANJAVIEQQL-UHFFFAOYSA-N dicarboxy carbonate Chemical compound OC(=O)OC(=O)OC(O)=O SYHPANJAVIEQQL-UHFFFAOYSA-N 0.000 abstract 2
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 abstract 1
210000004102 animal cell Anatomy 0.000 abstract 1
150000004697 chelate complex Chemical class 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
229910052742 iron Inorganic materials 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910001428 transition metal ion Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins

Landscapes

Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Cell Biology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT03004806T 2002-03-05 2003-03-04 Verbesserte methoden um säugetierzellen in vitro zu züchten ATE304047T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02004366		2002-03-05

Publications (1)

Publication Number	Publication Date
ATE304047T1 true ATE304047T1 (de)	2005-09-15

Family

ID=27798778

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03004806T ATE304047T1 (de)	2002-03-05	2003-03-04	Verbesserte methoden um säugetierzellen in vitro zu züchten

Country Status (11)

Country	Link
US (1)	US7390660B2 (de)
EP (1)	EP1342780B1 (de)
JP (2)	JP4476554B2 (de)
KR (1)	KR100576589B1 (de)
CN (1)	CN100398640C (de)
AT (1)	ATE304047T1 (de)
CA (1)	CA2417689C (de)
DE (1)	DE60301510T2 (de)
DK (1)	DK1342780T3 (de)
ES (1)	ES2248657T3 (de)
MX (1)	MXPA03001487A (de)

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EP1835022B1 (de) *	2005-01-05	2015-02-11	Chugai Seiyaku Kabushiki Kaisha	Zellkulturverfahren und dessen nutzung
DE102005046225B4 (de)	2005-09-28	2012-01-05	Cellca Gmbh	Verbessertes Zellkulturmedium
US8911964B2 (en)	2006-09-13	2014-12-16	Abbvie Inc.	Fed-batch method of making human anti-TNF-alpha antibody
AU2007294731B2 (en)	2006-09-13	2014-04-17	Abbvie Inc.	Cell culture improvements
TW200902708A (en)	2007-04-23	2009-01-16	Wyeth Corp	Methods of protein production using anti-senescence compounds
ES2657055T3 (es) *	2007-08-09	2018-03-01	Wyeth Llc	Uso de perfusión para mejorar la producción de un cultivo de células alimentado por lotes en biorreactores
BRPI0920572A8 (pt)	2008-10-20	2015-10-27	Abbott Lab	Inativação viral durante a purificação dos anticorpos
NZ592095A (en)	2008-10-20	2013-01-25	Abbott Lab	Isolation and purification of il-12 and tnf-alpha antibodies using protein a affinity chromatography
SI2493922T1 (sl)	2009-10-26	2017-06-30	F. Hoffmann-La Roche Ag	Postopek za proizvodnjo glikoziliranega imunoglobulina
WO2012091023A1 (ja)	2010-12-27	2012-07-05	協和発酵キリン株式会社	培地およびキレート剤を含む水溶液の調製方法
US9062106B2 (en)	2011-04-27	2015-06-23	Abbvie Inc.	Methods for controlling the galactosylation profile of recombinantly-expressed proteins
WO2013158279A1 (en)	2012-04-20	2013-10-24	Abbvie Inc.	Protein purification methods to reduce acidic species
US9067990B2 (en)	2013-03-14	2015-06-30	Abbvie, Inc.	Protein purification using displacement chromatography
WO2013158273A1 (en)	2012-04-20	2013-10-24	Abbvie Inc.	Methods to modulate c-terminal lysine variant distribution
WO2013176754A1 (en)	2012-05-24	2013-11-28	Abbvie Inc.	Novel purification of antibodies using hydrophobic interaction chromatography
HK1211981A1 (en)	2012-09-02	2016-06-03	Abbvie Inc.	Methods to control protein heterogeneity
US9512214B2 (en)	2012-09-02	2016-12-06	Abbvie, Inc.	Methods to control protein heterogeneity
HK1207960A1 (en)	2013-03-12	2016-02-19	Abbvie Inc.	Human antibodies that bind human tnf-alpha and methods of preparing the same
US9017687B1 (en)	2013-10-18	2015-04-28	Abbvie, Inc.	Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014159579A1 (en)	2013-03-14	2014-10-02	Abbvie Inc.	MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
US9499614B2 (en)	2013-03-14	2016-11-22	Abbvie Inc.	Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
US9598667B2 (en)	2013-10-04	2017-03-21	Abbvie Inc.	Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US11390663B2 (en)	2013-10-11	2022-07-19	Regeneron Pharmaceuticals, Inc.	Metabolically optimized cell culture
KR102243980B1 (ko)	2013-10-11	2021-04-26	리제너론 파마슈티칼스 인코포레이티드	대사적으로 최적화된 세포 배양
US8946395B1 (en)	2013-10-18	2015-02-03	Abbvie Inc.	Purification of proteins using hydrophobic interaction chromatography
US9085618B2 (en)	2013-10-18	2015-07-21	Abbvie, Inc.	Low acidic species compositions and methods for producing and using the same
US9181337B2 (en)	2013-10-18	2015-11-10	Abbvie, Inc.	Modulated lysine variant species compositions and methods for producing and using the same
US20150139988A1 (en)	2013-11-15	2015-05-21	Abbvie, Inc.	Glycoengineered binding protein compositions
EP3130661A4 (de)	2014-04-07	2018-03-07	Toyo Seikan Group Holdings, Ltd.	Kulturflüssigkeit für tierzellen und kulturgefäss
CN119301236A (zh)	2022-03-02	2025-01-10	瑞泽恩制药公司	用于抗体生产的生物反应器
WO2025209979A1 (en)	2024-04-04	2025-10-09	Roche Diagnostics Gmbh	METHOD FOR PRODUCING RECOMBINANT VIRUSES OR VIRUS-LIKE PARTICLES (VLPs) IN MAMMALIAN CELL LINES

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5328844A (en) *	1990-05-09	1994-07-12	University Of Colorado Foundation, Inc.	Culture media for mammalian cells
WO1993000423A1 (en)	1991-06-21	1993-01-07	Novo Nordisk A/S	Iron chelate culture medium additive
JP3046415B2 (ja) *	1991-10-04	2000-05-29	日水製薬株式会社	浮遊細胞用無血清合成培地
US5719050A (en) *	1993-12-24	1998-02-17	Eiken Chemical Co., Ltd.	Animal cell culturing media containing N-acetyl-L-glutamic acid
JPH0870858A (ja) *	1993-12-24	1996-03-19	Eiken Chem Co Ltd	動物細胞培養用培地
US5856179A (en) *	1994-03-10	1999-01-05	Genentech, Inc.	Polypeptide production in animal cell culture
WO1998041611A1 (en)	1997-03-20	1998-09-24	Regents Of The University Of Minnesota	Process for the continuous culture of cells
UA74557C2 (en) *	1999-09-03	2006-01-16	Applied Research Systems	A method for producing a heterologous secreted protein from chinese hamster ovaries cells grown on microcarriers
US6762053B2 (en)	2000-06-09	2004-07-13	Vitrolife, Inc.	Mammalian gamete and embryo culture media and culture media supplements
EP1360314B1 (de) *	2001-02-15	2009-01-14	Centocor, Inc.	Chemisch definiertes medium für kultivierte säugerzellen

2003
- 2003-01-30 CA CA002417689A patent/CA2417689C/en not_active Expired - Fee Related
- 2003-02-18 MX MXPA03001487A patent/MXPA03001487A/es active IP Right Grant
- 2003-03-03 US US10/376,392 patent/US7390660B2/en not_active Expired - Lifetime
- 2003-03-04 DE DE60301510T patent/DE60301510T2/de not_active Expired - Lifetime
- 2003-03-04 EP EP03004806A patent/EP1342780B1/de not_active Expired - Lifetime
- 2003-03-04 ES ES03004806T patent/ES2248657T3/es not_active Expired - Lifetime
- 2003-03-04 AT AT03004806T patent/ATE304047T1/de active
- 2003-03-04 DK DK03004806T patent/DK1342780T3/da active
- 2003-03-05 JP JP2003058803A patent/JP4476554B2/ja not_active Expired - Lifetime
- 2003-03-05 KR KR1020030013580A patent/KR100576589B1/ko not_active Expired - Fee Related
- 2003-03-05 CN CNB031070604A patent/CN100398640C/zh not_active Expired - Fee Related
2009
- 2009-10-05 JP JP2009231190A patent/JP5191970B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US7390660B2 (en)	2008-06-24
KR20030074204A (ko)	2003-09-19
JP5191970B2 (ja)	2013-05-08
JP2010000094A (ja)	2010-01-07
US20030175951A1 (en)	2003-09-18
DK1342780T3 (da)	2005-12-12
CN1442478A (zh)	2003-09-17
CA2417689C (en)	2006-05-09
DE60301510D1 (de)	2005-10-13
KR100576589B1 (ko)	2006-05-04
CA2417689A1 (en)	2003-09-05
JP4476554B2 (ja)	2010-06-09
EP1342780B1 (de)	2005-09-07
EP1342780A1 (de)	2003-09-10
ES2248657T3 (es)	2006-03-16
CN100398640C (zh)	2008-07-02
DE60301510T2 (de)	2006-06-14
MXPA03001487A (es)	2005-09-08
JP2003250533A (ja)	2003-09-09

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2006-10-15

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