ATE306255T1 - 19-nor-vitamin d3 derivate mit calciumspiegel erhöhender wirkung - Google Patents

19-nor-vitamin d3 derivate mit calciumspiegel erhöhender wirkung

Info

Publication number: ATE306255T1
Authority: AT; Austria
Prior art keywords: vitamin; derivatives; increase effect; calcium level; cancer
Prior art date: 1998-08-18

Application number

AT99928692T

Other languages

English (en)

Inventor

Hector F Deluca

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-18

Filing date

1999-06-16

Publication date

2005-10-15

1999-06-16 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

2005-10-15 Application granted granted Critical

2005-10-15 Publication of ATE306255T1 publication Critical patent/ATE306255T1/de

Links

OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title 1
229910052791 calcium Inorganic materials 0.000 title 1
239000011575 calcium Substances 0.000 title 1
206010006187 Breast cancer Diseases 0.000 abstract 1
208000026310 Breast neoplasm Diseases 0.000 abstract 1
206010009944 Colon cancer Diseases 0.000 abstract 1
206010060862 Prostate cancer Diseases 0.000 abstract 1
208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
239000011612 calcitriol Substances 0.000 abstract 1
208000029742 colonic neoplasm Diseases 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT99928692T 1998-08-18 1999-06-16 19-nor-vitamin d3 derivate mit calciumspiegel erhöhender wirkung ATE306255T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/135,947 US5962707A (en)	1998-08-18	1998-08-18	19-nor-vitamin D3 compounds with calcemic activity
PCT/US1999/013541 WO2000010548A2 (en)	1998-08-18	1999-06-16	19-nor-vitamin d3 compounds with calcemic activity

Publications (1)

Publication Number	Publication Date
ATE306255T1 true ATE306255T1 (de)	2005-10-15

Family

ID=22470513

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99928692T ATE306255T1 (de)	1998-08-18	1999-06-16	19-nor-vitamin d3 derivate mit calciumspiegel erhöhender wirkung

Country Status (8)

Country	Link
US (2)	US5962707A (de)
EP (2)	EP1433780A1 (de)
JP (1)	JP4282234B2 (de)
AT (1)	ATE306255T1 (de)
AU (1)	AU4569599A (de)
DE (1)	DE69927714T2 (de)
ES (1)	ES2249013T3 (de)
WO (1)	WO2000010548A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6306844B1 (en) *	1997-03-17	2001-10-23	Wisconsin Alumni Research Foundation	Use of 2α-methyl-19-nor-20(S)-1α, 25-dihydroxyvitamin D3 to increase bone strength
US6392071B1 (en)	1997-03-17	2002-05-21	Wisconsin Alumni: Research Foundation	26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds
US6316642B1 (en)	1997-03-17	2001-11-13	Wisconsin Alumni Research Foundation	26,27-Homologated-20-EPI-2alkyl-19-nor-vitamin D compounds
US20030114482A1 (en) *	1999-12-15	2003-06-19	Maurizio Pacifici	Use of retinoid receptor antagonists or agonists in the treatment of cartilage and bone pathologies
EP1598360A4 (de)	2003-02-25	2010-04-07	Knc Lab Co Ltd	Neue zwischenprodukte für die synthese von vitamin-d-derivaten
CA2586679A1 (en)	2004-11-12	2006-05-18	Bioxell Spa	Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
WO2006057884A2 (en) *	2004-11-22	2006-06-01	Wisconsin Alumni Research Foundation	2α-METHYL AND 2ß-METHYL ANALOGS OF 19,26,27-TRINOR-(20S)-1α-HYDROXYVITAMIN D3 AND THEIR USES
WO2006093291A1 (ja) *	2005-03-04	2006-09-08	Tokyo Medical And Dental University	１９－ノルビタミンｄ誘導体

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4847012A (en) *	1988-04-29	1989-07-11	Wisconsin Alumni Research Foundation	Vitamin D related compounds and processes for their preparation
US4851401A (en) *	1988-07-14	1989-07-25	Wisconsin Alumni Research Foundation	Novel cyclopentano-vitamin D analogs
GB8904154D0 (en) *	1989-02-23	1989-04-05	Leo Pharm Prod Ltd	Chemical compounds
US5246925A (en) *	1989-03-09	1993-09-21	Wisconsin Alumni Research Foundation	19-nor-vitamin D compounds for use in treating hyperparathyroidism
CA1333616C (en) *	1989-03-09	1994-12-20	Hector F. Deluca	19-nor-vitamin d compounds
ATE173401T1 (de) *	1990-09-07	1998-12-15	Wisconsin Alumni Res Found	Neue verwendung von 1-alpha-hydroxylierten-19-nor-vitamin-d-verbind ngen zur behandlung von psoriasis
AU650751B2 (en) *	1991-05-28	1994-06-30	Wisconsin Alumni Research Foundation	Novel synthesis of 19-nor vitamin D compounds
US5086191A (en) *	1991-05-28	1992-02-04	Wisconsin Alumni Research Foundation	Intermediates for the synthesis of 19-nor vitamin D compounds
KR960013798B1 (ko) *	1992-04-24	1996-10-10	재단법인 한국전자통신연구소	평면 도파로형 공간 스위치
AU699200B2 (en) *	1993-07-09	1998-11-26	Roger Bouillon	Novel structural analogues of vitamin D

1998
- 1998-08-18 US US09/135,947 patent/US5962707A/en not_active Expired - Fee Related
1999
- 1999-05-13 US US09/311,403 patent/US5981780A/en not_active Expired - Fee Related
- 1999-06-16 WO PCT/US1999/013541 patent/WO2000010548A2/en not_active Ceased
- 1999-06-16 EP EP04003399A patent/EP1433780A1/de not_active Withdrawn
- 1999-06-16 JP JP2000565870A patent/JP4282234B2/ja not_active Expired - Fee Related
- 1999-06-16 DE DE69927714T patent/DE69927714T2/de not_active Expired - Fee Related
- 1999-06-16 AT AT99928692T patent/ATE306255T1/de not_active IP Right Cessation
- 1999-06-16 ES ES99928692T patent/ES2249013T3/es not_active Expired - Lifetime
- 1999-06-16 EP EP99928692A patent/EP1143949B1/de not_active Expired - Lifetime
- 1999-06-16 AU AU45695/99A patent/AU4569599A/en not_active Abandoned

Also Published As

Publication number	Publication date
JP4282234B2 (ja)	2009-06-17
EP1143949A3 (de)	2002-09-11
AU4569599A (en)	2000-03-14
US5981780A (en)	1999-11-09
DE69927714D1 (de)	2006-02-23
EP1143949B1 (de)	2005-10-12
EP1433780A1 (de)	2004-06-30
WO2000010548A2 (en)	2000-03-02
US5962707A (en)	1999-10-05
JP2002537222A (ja)	2002-11-05
EP1143949A2 (de)	2001-10-17
DE69927714T2 (de)	2006-07-06
ES2249013T3 (es)	2006-03-16
WO2000010548A3 (en)	2001-11-29

Legal Events

Date	Code	Title	Description
2006-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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IL150767A (en)	2013-09-30	Benzopyran-containing compounds and their use in manufacture of medicaments for treatment of estrogen sensitive diseases such as endometrial cancer
MX9200675A (es)	1992-08-01	Derivados de 2,4-diaminoquinazolinas para mejorar la actividad antitumoral.
AR020019A1 (es)	2002-03-27	Composicion farmaceutica para la prevencion o el tratamiento de cancer de mama
CY1107116T1 (el)	2012-10-24	Νεες κυκλοεξυλ σουλφονες
DE60041333D1 (de)	2009-02-26	Hen prostatkrebs exprimiert wird, und deren verwendungen
ES2391382T8 (es)	2018-08-23	Compuestos de aril-urea en combinación con otros agentes citostáticos o citotóxicos para tratamiento de cánceres humanos
FR2657259B1 (de)	1994-08-19
DK0944389T3 (da)	2008-11-17	Oprensede sammensætninger af 10-propargyl-10-deazaaminopterin og fremgangsmåder til anvendelse deraf i behandlingen af tumorer
ES2056180T3 (es)	1994-10-01	Nuevos derivados de 2'-halometiliden, 2'-eteniliden y 2'-etinil citidina.
DE69927714D1 (de)	2006-02-23	19-nor-vitamin d3 derivate mit calciumspiegel erhöhender wirkung
ES2179204T3 (es)	2003-01-16	Hidrazinas 2-aminocarbonil-1,2-bis(metilsulfonil)-1-sustituidas antitumorales.
ATE471309T1 (de)	2010-07-15	Neuartige retinoide und deren verwendung
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DE69735892D1 (de)	2006-06-22	Mittel zur vorbeugung bzw. heilung der stomatitis
PT1472375E (pt)	2009-05-19	Produtos génicos expressos diferencialmente em células cancerígenas da mama e seus métodos de utilização
DK0510913T3 (da)	2000-10-16	Farmaceutiske sammensætninger indeholdende calcitonin
AU1128801A (en)	2001-04-17	Agents for treating human diseases, especially for treating tumors such as colonic cancers and melanomas or for regenerating tissue and promoting hair growth
DK1140147T3 (da)	2007-03-26	hCG-terapi til behandling af metastatisk brystcancer
FI913531A0 (fi)	1991-07-23	Anvaendning av 1,2-bensopyronderivater till behandling av maligna tumoerer hos maenniskan.
MX9709683A (es)	1998-06-28	Uso de derivados de vitamina d4 para tratamiento contra el cancer.
ITAR980038A0 (it)	1998-12-04	Suola per calzature e mezzi perfezionati per l'aerazione del piede
IT241482Y1 (it)	2001-05-09	Lacci da scarpe atti a consentire l'entrata e l'uscita del piedesenza slegare le scarpe