ATE306929T1 - Inositolphosphoglycan und ribose zur behandlung von ischämischen-reperfusionschaden - Google Patents

Inositolphosphoglycan und ribose zur behandlung von ischämischen-reperfusionschaden

Info

Publication number: ATE306929T1
Authority: AT; Austria
Prior art keywords: treatment; ribose; reperfusion injury; ischemic; inositol phosphoglycan
Prior art date: 1998-06-29

Application number

AT99922293T

Other languages

English (en)

Inventor

Thomas William Rademacher

Leslie Greenbaum

Patricia Mclean

Original Assignee

Sylus Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-29

Filing date

1999-05-12

Publication date

2005-11-15

1999-05-12 Application filed by Sylus Pharmaceuticals Ltd filed Critical Sylus Pharmaceuticals Ltd

2005-11-15 Application granted granted Critical

2005-11-15 Publication of ATE306929T1 publication Critical patent/ATE306929T1/de

Links

206010063837 Reperfusion injury Diseases 0.000 title abstract 2
PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 title abstract 2
HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 title abstract 2
SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 title 1
HMFHBZSHGGEWLO-AIHAYLRMSA-N alpha-D-ribose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-AIHAYLRMSA-N 0.000 title 1
CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 title 1
229960000367 inositol Drugs 0.000 title 1
CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 title 1
239000000203 mixture Substances 0.000 abstract 2
HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 abstract 1
230000002438 mitochondrial effect Effects 0.000 abstract 1
210000000056 organ Anatomy 0.000 abstract 1
230000001590 oxidative effect Effects 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
238000002054 transplantation Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT99922293T 1998-06-29 1999-05-12 Inositolphosphoglycan und ribose zur behandlung von ischämischen-reperfusionschaden ATE306929T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9814039.5A GB9814039D0 (en)	1998-06-29	1998-06-29	Materials and methods relating to the prevention or treatment of ischaemia-reperfusion injury
PCT/GB1999/001499 WO2000000205A1 (en)	1998-06-29	1999-05-12	Inositolphosphoglycan and ribose for treatment of ischaemia-reperfusion injury

Publications (1)

Publication Number	Publication Date
ATE306929T1 true ATE306929T1 (de)	2005-11-15

Family

ID=10834599

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99922293T ATE306929T1 (de)	1998-06-29	1999-05-12	Inositolphosphoglycan und ribose zur behandlung von ischämischen-reperfusionschaden

Country Status (9)

Country	Link
US (1)	US6900182B1 (de)
EP (1)	EP1091743B1 (de)
JP (1)	JP2002519328A (de)
AT (1)	ATE306929T1 (de)
AU (1)	AU748892B2 (de)
CA (1)	CA2332969A1 (de)
DE (1)	DE69927815T2 (de)
GB (1)	GB9814039D0 (de)
WO (1)	WO2000000205A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2001245463A1 (en) *	2000-03-07	2001-09-17	Millennium Pharmaceuticals, Inc.	26583, a novel serine/threonine phosphatase and uses therefor
US6953781B2 (en) *	2000-05-12	2005-10-11	Rodaris Pharmaceuticals Limited	Compounds and their uses
JPWO2007129618A1 (ja) *	2006-05-08	2009-09-17	国立大学法人香川大学	好中球の活性化および遊走因子の抑制剤およびその利用
WO2009123742A1 (en) *	2008-04-02	2009-10-08	St Cyr John A	Use of ribose in first response to acute myocardial infarction

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0290496B2 (de) *	1986-10-06	1995-12-20	The University Of Virginia Alumni Patents Foundation	Verwendung einer adenosin, hypoxanthin und ribose enthaltender lösung zur schonung des herzens während chirurgischer eingriffe
US4871718A (en) *	1987-12-29	1989-10-03	Raymond A. Roncari	Composition of matter for increasing intracellular ATP levels and physical performance levels and for increasing the rate of wound repair
US6294520B1 (en) *	1989-03-27	2001-09-25	Albert T. Naito	Material for passage through the blood-brain barrier
WO1997047192A1 (en) *	1996-06-14	1997-12-18	Biostore New Zealand Limited	Compositions and methods for the preservation of living tissues
GB9618934D0 (en) *	1996-09-11	1996-10-23	Univ London	Inositol phosphoglycans for therapeutic use in the treatment of diabetes and obesity
DE19649350A1 (de) *	1996-11-28	1998-06-04	Hoechst Ag	Inositolglykane mit insulinartiger Wirkung

1998
- 1998-06-29 GB GBGB9814039.5A patent/GB9814039D0/en not_active Ceased
1999
- 1999-05-12 US US09/719,909 patent/US6900182B1/en not_active Expired - Fee Related
- 1999-05-12 DE DE69927815T patent/DE69927815T2/de not_active Expired - Fee Related
- 1999-05-12 AU AU39402/99A patent/AU748892B2/en not_active Ceased
- 1999-05-12 JP JP2000556790A patent/JP2002519328A/ja active Pending
- 1999-05-12 AT AT99922293T patent/ATE306929T1/de not_active IP Right Cessation
- 1999-05-12 EP EP99922293A patent/EP1091743B1/de not_active Expired - Lifetime
- 1999-05-12 WO PCT/GB1999/001499 patent/WO2000000205A1/en not_active Ceased
- 1999-05-12 CA CA002332969A patent/CA2332969A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US6900182B1 (en)	2005-05-31
EP1091743A1 (de)	2001-04-18
WO2000000205A1 (en)	2000-01-06
CA2332969A1 (en)	2000-01-06
JP2002519328A (ja)	2002-07-02
AU748892B2 (en)	2002-06-13
DE69927815D1 (de)	2006-03-02
AU3940299A (en)	2000-01-17
EP1091743B1 (de)	2005-10-19
GB9814039D0 (en)	1998-08-26
DE69927815T2 (de)	2006-07-20

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Legal Events

Date	Code	Title	Description
2006-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties